Mus musculus

0 known processes

Gls2

glutaminase 2 (liver, mitochondrial)

(Aliases: Lga,A330074B06Rik,AI195532,KIAA4146,GA,GLS)

Gls2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.139
Mouse
amine metabolic process GO:0009308 45 0.068
transmembrane transport GO:0055085 412 0.050
cellular amine metabolic process GO:0044106 44 0.050
cellular ketone metabolic process GO:0042180 84 0.049
cellular lipid metabolic process GO:0044255 323 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
regulation of membrane potential GO:0042391 192 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
oxidation reduction process GO:0055114 342 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.032
nucleotide metabolic process GO:0009117 332 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.031
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.029
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.029
purine containing compound metabolic process GO:0072521 311 0.029
organic acid biosynthetic process GO:0016053 86 0.029
Mouse
alpha amino acid metabolic process GO:1901605 59 0.029
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.028
Mouse
regulation of organelle organization GO:0033043 289 0.027
aromatic compound catabolic process GO:0019439 286 0.027
ion transmembrane transport GO:0034220 361 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
mapk cascade GO:0000165 281 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
sulfur compound metabolic process GO:0006790 100 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
cation transport GO:0006812 399 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
heterocycle catabolic process GO:0046700 280 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
peptidyl amino acid modification GO:0018193 336 0.024
dna metabolic process GO:0006259 303 0.024
gland development GO:0048732 330 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.023
regulation of cell cycle GO:0051726 281 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
response to organonitrogen compound GO:0010243 246 0.023
membrane organization GO:0061024 245 0.023
carbohydrate metabolic process GO:0005975 230 0.023
cell type specific apoptotic process GO:0097285 268 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
positive regulation of cell development GO:0010720 237 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
camera type eye development GO:0043010 266 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
Human
macromolecule catabolic process GO:0009057 281 0.022
synaptic transmission GO:0007268 329 0.022
Mouse
lipid biosynthetic process GO:0008610 179 0.022
regulation of neuron differentiation GO:0045664 281 0.022
ras protein signal transduction GO:0007265 77 0.021
cation transmembrane transport GO:0098655 266 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
regulation of protein kinase activity GO:0045859 232 0.021
muscle tissue development GO:0060537 308 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
nucleoside metabolic process GO:0009116 246 0.021
nitrogen compound transport GO:0071705 271 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
regulation of transferase activity GO:0051338 263 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of hydrolase activity GO:0051336 246 0.020
cytoplasmic transport GO:0016482 234 0.020
spermatogenesis GO:0007283 284 0.019
regulation of cell projection organization GO:0031344 206 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
regulation of mapk cascade GO:0043408 248 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
small molecule biosynthetic process GO:0044283 132 0.018
Mouse
organelle fission GO:0048285 170 0.018
neuronal action potential GO:0019228 54 0.018
immune effector process GO:0002252 321 0.018
multicellular organismal signaling GO:0035637 91 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
skeletal system development GO:0001501 356 0.018
organophosphate catabolic process GO:0046434 232 0.018
anion transport GO:0006820 177 0.018
action potential GO:0001508 78 0.018
rho protein signal transduction GO:0007266 32 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
negative regulation of molecular function GO:0044092 258 0.018
transmission of nerve impulse GO:0019226 76 0.018
cellular homeostasis GO:0019725 240 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
axonogenesis GO:0007409 274 0.017
muscle cell differentiation GO:0042692 261 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of anatomical structure size GO:0090066 178 0.017
microtubule based process GO:0007017 236 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.016
nucleotide catabolic process GO:0009166 217 0.016
nucleoside catabolic process GO:0009164 206 0.016
striated muscle tissue development GO:0014706 293 0.016
forebrain development GO:0030900 302 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
cellular amino acid catabolic process GO:0009063 25 0.016
Mouse
purine containing compound catabolic process GO:0072523 213 0.016
positive regulation of nervous system development GO:0051962 221 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
renal system development GO:0072001 225 0.016
nuclear division GO:0000280 158 0.016
regulation of system process GO:0044057 200 0.016
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.015
intracellular protein transport GO:0006886 204 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
male gamete generation GO:0048232 285 0.015
sensory perception GO:0007600 245 0.015
protein maturation GO:0051604 176 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
protein catabolic process GO:0030163 221 0.015
regulation of neuron projection development GO:0010975 169 0.015
urogenital system development GO:0001655 261 0.015
regulation of cellular response to stress GO:0080135 159 0.015
lateral inhibition GO:0046331 1 0.015
regulation of cell migration GO:0030334 219 0.015
protein ubiquitination GO:0016567 171 0.015
cell adhesion GO:0007155 329 0.015
neuron death GO:0070997 154 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
skeletal system morphogenesis GO:0048705 203 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
positive regulation of neuron differentiation GO:0045666 141 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
glycoprotein metabolic process GO:0009100 116 0.014
cofactor metabolic process GO:0051186 80 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
alcohol metabolic process GO:0006066 116 0.014
fat cell differentiation GO:0045444 160 0.014
connective tissue development GO:0061448 179 0.014
positive regulation of cell death GO:0010942 224 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of hormone levels GO:0010817 211 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
regulation of protein localization GO:0032880 231 0.014
small molecule catabolic process GO:0044282 71 0.014
Mouse
myeloid cell differentiation GO:0030099 233 0.014
apoptotic signaling pathway GO:0097190 306 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of proteolysis GO:0030162 164 0.014
glucose homeostasis GO:0042593 128 0.014
nucleocytoplasmic transport GO:0006913 139 0.013
inflammatory response GO:0006954 244 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
protein localization to organelle GO:0033365 185 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cellular chemical homeostasis GO:0055082 215 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
cellular alcohol metabolic process GO:0044107 3 0.013
response to organic cyclic compound GO:0014070 198 0.013
lipoprotein metabolic process GO:0042157 43 0.013
ossification GO:0001503 216 0.013
homeostasis of number of cells GO:0048872 210 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
chromatin organization GO:0006325 206 0.013
glycerolipid metabolic process GO:0046486 122 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
blood circulation GO:0008015 195 0.013
circulatory system process GO:0003013 197 0.013
mitotic cell cycle GO:0000278 195 0.013
response to acid chemical GO:0001101 111 0.013
regulation of cytokine production GO:0001817 266 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
metal ion homeostasis GO:0055065 189 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
organic acid transport GO:0015849 101 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
cellular response to lipid GO:0071396 145 0.013
extracellular structure organization GO:0043062 148 0.013
regulation of cellular component size GO:0032535 121 0.013
regulation of transmembrane transport GO:0034762 128 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
retina development in camera type eye GO:0060041 119 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
skin development GO:0043588 220 0.013
negative regulation of phosphorylation GO:0042326 166 0.012
compound eye development GO:0048749 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of secretion by cell GO:1903530 249 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
meiotic nuclear division GO:0007126 115 0.012
bone development GO:0060348 120 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of cell activation GO:0050865 289 0.012
cytokine production GO:0001816 319 0.012
organelle localization GO:0051640 179 0.012
nuclear transport GO:0051169 139 0.012
chemotaxis GO:0006935 247 0.012
response to growth factor GO:0070848 198 0.012
sensory organ morphogenesis GO:0090596 242 0.012
protein targeting GO:0006605 143 0.012
anatomical structure homeostasis GO:0060249 145 0.012
coenzyme metabolic process GO:0006732 52 0.012
regulation of secretion GO:0051046 274 0.012
t cell activation GO:0042110 289 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of cell cycle process GO:0010564 160 0.012
hormone secretion GO:0046879 128 0.012
neuron apoptotic process GO:0051402 142 0.012
lymphocyte differentiation GO:0030098 242 0.012
leukocyte differentiation GO:0002521 342 0.012
maintenance of location GO:0051235 89 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
carbohydrate homeostasis GO:0033500 128 0.012
phospholipid metabolic process GO:0006644 87 0.012
response to extracellular stimulus GO:0009991 127 0.012
endomembrane system organization GO:0010256 147 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
hexose metabolic process GO:0019318 98 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
negative regulation of cell cycle GO:0045786 123 0.011
regulation of homeostatic process GO:0032844 182 0.011
neuron migration GO:0001764 122 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cellular ion homeostasis GO:0006873 165 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
response to oxidative stress GO:0006979 123 0.011
rna interference GO:0016246 2 0.011
cellular amide metabolic process GO:0043603 58 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
meiotic cell cycle GO:0051321 122 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
Mouse
tissue remodeling GO:0048771 102 0.011
epithelial cell development GO:0002064 159 0.011
fertilization GO:0009566 127 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
positive regulation of kinase activity GO:0033674 155 0.011
adult behavior GO:0030534 135 0.011
negative regulation of nervous system development GO:0051961 156 0.011
cartilage development GO:0051216 140 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of response to wounding GO:1903034 189 0.011
rhythmic process GO:0048511 174 0.011
organic anion transport GO:0015711 137 0.011
germ cell development GO:0007281 185 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
fatty acid metabolic process GO:0006631 121 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
response to inorganic substance GO:0010035 96 0.011
amide transport GO:0042886 138 0.011
cellular protein catabolic process GO:0044257 155 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
cell maturation GO:0048469 127 0.011
peptide transport GO:0015833 133 0.011
regulation of defense response GO:0031347 233 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
protein processing GO:0016485 163 0.011
skeletal muscle organ development GO:0060538 163 0.011
dephosphorylation GO:0016311 129 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
myelination GO:0042552 74 0.011
epithelial cell proliferation GO:0050673 174 0.011
developmental maturation GO:0021700 193 0.011
wound healing GO:0042060 157 0.011
actin cytoskeleton organization GO:0030036 220 0.011
monosaccharide metabolic process GO:0005996 106 0.010
placenta development GO:0001890 140 0.010
cation homeostasis GO:0055080 212 0.010
protein localization to nucleus GO:0034504 121 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
telencephalon development GO:0021537 186 0.010
divalent metal ion transport GO:0070838 172 0.010
kidney development GO:0001822 213 0.010
respiratory system development GO:0060541 190 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
response to lipopolysaccharide GO:0032496 128 0.010
establishment of blood nerve barrier GO:0008065 3 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
locomotory behavior GO:0007626 195 0.010
organ growth GO:0035265 117 0.010
chromatin modification GO:0016568 187 0.010
response to radiation GO:0009314 165 0.010
cell division GO:0051301 120 0.010
cardiac muscle tissue development GO:0048738 130 0.010
carboxylic acid catabolic process GO:0046395 51 0.010
Mouse
regulation of intracellular transport GO:0032386 159 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
respiratory tube development GO:0030323 167 0.010
protein polymerization GO:0051258 57 0.010
tissue homeostasis GO:0001894 115 0.010
stem cell differentiation GO:0048863 268 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
negative regulation of cell development GO:0010721 169 0.010

Gls2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.018
musculoskeletal system disease DOID:17 0 0.014
inherited metabolic disorder DOID:655 0 0.012
central nervous system disease DOID:331 0 0.012
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
bone disease DOID:0080001 0 0.010
connective tissue disease DOID:65 0 0.010
sensory system disease DOID:0050155 0 0.010