|
ion transmembrane transport
|
GO:0034220 |
361 |
0.987
|
Mouse Fly |
|
synaptic transmission
|
GO:0007268 |
329 |
0.943
|
Fly |
|
cation transport
|
GO:0006812 |
399 |
0.936
|
Mouse Fly |
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.820
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.810
|
Mouse Fly |
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.794
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.770
|
Mouse |
|
cellular homeostasis
|
GO:0019725 |
240 |
0.753
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.704
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.672
|
|
|
cognition
|
GO:0050890 |
149 |
0.642
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.626
|
Fly |
|
visual learning
|
GO:0008542 |
44 |
0.623
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.619
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.616
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.598
|
Mouse |
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.589
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.588
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.588
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.579
|
Mouse |
|
transmembrane transport
|
GO:0055085 |
412 |
0.573
|
Mouse Fly |
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.572
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.571
|
Fly |
|
learning or memory
|
GO:0007611 |
148 |
0.564
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.561
|
Fly |
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.558
|
Mouse |
|
axonogenesis
|
GO:0007409 |
274 |
0.542
|
Fly |
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.537
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.536
|
Fly |
|
locomotory behavior
|
GO:0007626 |
195 |
0.525
|
Fly |
|
action potential
|
GO:0001508 |
78 |
0.498
|
Mouse Fly |
|
cation homeostasis
|
GO:0055080 |
212 |
0.494
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.491
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.485
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.479
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.478
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.476
|
Mouse |
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.470
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.459
|
Mouse |
|
visual behavior
|
GO:0007632 |
45 |
0.457
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.450
|
Mouse Fly |
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.427
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.427
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.423
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.423
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.416
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.416
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.411
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.409
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.392
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.389
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.379
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.379
|
Mouse |
|
adult walking behavior
|
GO:0007628 |
41 |
0.378
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.377
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.362
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.355
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.355
|
Fly |
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.355
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.354
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.353
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.352
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.351
|
Mouse |
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.345
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.342
|
Fly |
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.340
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.339
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.338
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.335
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.323
|
|
|
nerve development
|
GO:0021675 |
67 |
0.321
|
Mouse |
|
amide transport
|
GO:0042886 |
138 |
0.317
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.315
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.313
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.308
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.307
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.307
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.306
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.303
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.303
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.297
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.297
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.286
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.283
|
Fly |
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.282
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.282
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.278
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.278
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.278
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.276
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.276
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.270
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.269
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.269
|
|
|
associative learning
|
GO:0008306 |
61 |
0.266
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.266
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.265
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.258
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.257
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.254
|
Mouse |
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.254
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.254
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.248
|
Fly |
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.246
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.246
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.243
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.242
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.239
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.239
|
|
|
optic nerve structural organization
|
GO:0021633 |
2 |
0.235
|
Mouse |
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.234
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.233
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.232
|
Mouse |
|
mapk cascade
|
GO:0000165 |
281 |
0.230
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.229
|
Mouse |
|
organic anion transport
|
GO:0015711 |
137 |
0.227
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.224
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.224
|
|
|
heart process
|
GO:0003015 |
94 |
0.224
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.224
|
|
|
regulation of lyase activity
|
GO:0051339 |
13 |
0.223
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
8 |
0.222
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.221
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.216
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.213
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.212
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.210
|
|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
4 |
0.209
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.208
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.206
|
Fly |
|
synapse assembly
|
GO:0007416 |
56 |
0.205
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.203
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.202
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.202
|
|
|
bone development
|
GO:0060348 |
120 |
0.200
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.200
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.200
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.200
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.199
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.198
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.198
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.197
|
Mouse |
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.197
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.194
|
|
|
fear response
|
GO:0042596 |
33 |
0.193
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.191
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.191
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.187
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.187
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.186
|
Fly |
|
regulation of heart rate
|
GO:0002027 |
36 |
0.184
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.184
|
|
|
anion transport
|
GO:0006820 |
177 |
0.180
|
|
|
learning
|
GO:0007612 |
98 |
0.180
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.178
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.178
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.176
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.175
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.173
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.173
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.173
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.170
|
Fly |
|
neuron migration
|
GO:0001764 |
122 |
0.170
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.169
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.168
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.167
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.161
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.161
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.160
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.160
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.157
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.155
|
|
|
regulation of g protein activated inward rectifier potassium channel activity
|
GO:1900128 |
1 |
0.155
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.154
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.154
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.154
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.153
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.153
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.153
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.152
|
|
|
positive regulation of heart rate
|
GO:0010460 |
10 |
0.150
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.150
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.150
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.149
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.148
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.146
|
|
|
memory
|
GO:0007613 |
58 |
0.144
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.144
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.144
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.144
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.143
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.142
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.142
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.141
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.141
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.141
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.140
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.140
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.139
|
|
|
response to amine
|
GO:0014075 |
16 |
0.139
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
18 |
0.139
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.139
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.138
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.136
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.135
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.135
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.135
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.135
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.133
|
|
|
regulation of acetylcholine secretion neurotransmission
|
GO:0014056 |
2 |
0.132
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.131
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.131
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.131
|
Mouse Fly |
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.131
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.130
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.129
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.128
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.127
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.127
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.127
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.126
|
|
|
mating
|
GO:0007618 |
27 |
0.126
|
Fly |
|
gonadotrophin releasing hormone neuronal migration to the hypothalamus
|
GO:0021828 |
3 |
0.125
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.125
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.124
|
|
|
cell division
|
GO:0051301 |
120 |
0.124
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
10 |
0.124
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.123
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.123
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.123
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.122
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.122
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.122
|
Fly |
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.121
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.118
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.118
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.118
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.118
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.118
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.118
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.117
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.117
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.117
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.117
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.117
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.115
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.115
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.115
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
16 |
0.115
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.115
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.114
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.114
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.113
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.113
|
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.113
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.113
|
|
|
sensitization
|
GO:0046960 |
2 |
0.113
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.113
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.111
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.109
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.108
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.108
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.108
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.107
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.106
|
|
|
ear development
|
GO:0043583 |
200 |
0.105
|
|
|
mating behavior sex discrimination
|
GO:0048047 |
1 |
0.105
|
Fly |
|
acetylcholine transport
|
GO:0015870 |
2 |
0.104
|
|
|
visual perception
|
GO:0007601 |
52 |
0.104
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.104
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.103
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.103
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.102
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.101
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.101
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.100
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.099
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.099
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.099
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.098
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.098
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.098
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.097
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.097
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.097
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.097
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.095
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.095
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.095
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.094
|
|
|
regulation of inward rectifier potassium channel activity
|
GO:1901979 |
1 |
0.093
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.093
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.093
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
16 |
0.093
|
Mouse |
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.092
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.092
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.091
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.091
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.090
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.090
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.090
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.089
|
|
|
cell growth
|
GO:0016049 |
130 |
0.089
|
Fly |
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.088
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.088
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
11 |
0.088
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.088
|
|
|
regulation of saliva secretion
|
GO:0046877 |
2 |
0.087
|
|
|
relaxation of muscle
|
GO:0090075 |
18 |
0.087
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.087
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.086
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.086
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.086
|
|
|
myelination
|
GO:0042552 |
74 |
0.086
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.086
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.085
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.085
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.085
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.085
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.085
|
|
|
tube formation
|
GO:0035148 |
140 |
0.083
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.083
|
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
6 |
0.083
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.083
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.083
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.083
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.082
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.082
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.082
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.081
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.080
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.080
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.080
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.079
|
|
|
cranial nerve structural organization
|
GO:0021604 |
13 |
0.079
|
Mouse |
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
5 |
0.079
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.078
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.078
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.078
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.078
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.077
|
|
|
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering
|
GO:0097113 |
3 |
0.077
|
|
|
long term synaptic depression
|
GO:0060292 |
13 |
0.076
|
|
|
dicarboxylic acid transport
|
GO:0006835 |
29 |
0.076
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.076
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.076
|
Mouse |
|
glucose homeostasis
|
GO:0042593 |
128 |
0.075
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.075
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.074
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
7 |
0.074
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.073
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.073
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
23 |
0.072
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.072
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.072
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.072
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.072
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.072
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
24 |
0.072
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.071
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.071
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.070
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.070
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.068
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.068
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.068
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.068
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.068
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.068
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.068
|
|
|
detection of visible light
|
GO:0009584 |
14 |
0.068
|
Fly |
|
neural tube development
|
GO:0021915 |
160 |
0.067
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.067
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.067
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.067
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.066
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.066
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.066
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.065
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.065
|
Fly |
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.065
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.065
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.065
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.065
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.065
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.065
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.064
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.064
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.064
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.064
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.064
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.063
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.063
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.063
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
44 |
0.063
|
|
|
digestion
|
GO:0007586 |
40 |
0.063
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.063
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.063
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.062
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.062
|
|
|
receptor internalization
|
GO:0031623 |
16 |
0.062
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.060
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.060
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.060
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
7 |
0.060
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.060
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.060
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.060
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.060
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.060
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.060
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.059
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
26 |
0.059
|
Mouse |
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.059
|
Fly |
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.059
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.058
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.058
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.057
|
|
|
dopamine metabolic process
|
GO:0042417 |
23 |
0.057
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.057
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.057
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.057
|
|
|
positive regulation of synaptic transmission glutamatergic
|
GO:0051968 |
8 |
0.057
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.057
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.057
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.056
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.056
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.056
|
|
|
cerebral cortex gabaergic interneuron differentiation
|
GO:0021892 |
9 |
0.056
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.055
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.055
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.055
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.055
|
|
|
tube closure
|
GO:0060606 |
91 |
0.054
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.054
|
Mouse |
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.054
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.054
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.054
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
12 |
0.054
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.054
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.054
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.054
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.054
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.054
|
|
|
serotonin metabolic process
|
GO:0042428 |
8 |
0.054
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.054
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.053
|
|
|
substrate independent telencephalic tangential migration
|
GO:0021826 |
8 |
0.053
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.052
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.052
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.052
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.052
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.052
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.052
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
14 |
0.052
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.052
|
|
|
negative regulation of behavior
|
GO:0048521 |
14 |
0.051
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.051
|
Fly |
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.051
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.051
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.051
|
|
|
optic nerve development
|
GO:0021554 |
8 |
0.051
|
Mouse |
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.050
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.050
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
22 |
0.049
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.049
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.049
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.048
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.048
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.048
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.048
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.048
|
|
|
renal system development
|
GO:0072001 |
225 |
0.048
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.048
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
19 |
0.048
|
|
|
regulation of white fat cell proliferation
|
GO:0070350 |
2 |
0.048
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.048
|
Mouse Fly |
|
membrane depolarization during sa node cell action potential
|
GO:0086046 |
2 |
0.047
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.047
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.047
|
Fly |
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.047
|
|
|
pallium development
|
GO:0021543 |
120 |
0.047
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.047
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.047
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.047
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.047
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.047
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.047
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.047
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.046
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.046
|
|
|
directional locomotion
|
GO:0033058 |
3 |
0.046
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.046
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.045
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
16 |
0.045
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.045
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.045
|
|