Mus musculus

0 known processes

Siah1b

seven in absentia 1B

(Aliases: Sinh1b,AA960570)

Siah1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.266
Human
intrinsic apoptotic signaling pathway GO:0097193 132 0.262
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.174
Human Mouse
regulation of cell cycle GO:0051726 281 0.151
positive regulation of apoptotic signaling pathway GO:2001235 95 0.150
Human
positive regulation of programmed cell death GO:0043068 218 0.144
Human
protein ubiquitination GO:0016567 171 0.131
Human Mouse
cellular protein catabolic process GO:0044257 155 0.113
Human Mouse Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.104
Human
meiotic nuclear division GO:0007126 115 0.088
Mouse
organelle fission GO:0048285 170 0.084
Mouse
pole plasm assembly GO:0007315 2 0.084
negative regulation of cellular protein metabolic process GO:0032269 247 0.080
negative regulation of protein metabolic process GO:0051248 282 0.080
nucleoside triphosphate metabolic process GO:0009141 230 0.079
nuclear division GO:0000280 158 0.072
Mouse
negative regulation of molecular function GO:0044092 258 0.070
response to radiation GO:0009314 165 0.069
meiotic cell cycle GO:0051321 122 0.068
Mouse
regulation of cell cycle process GO:0010564 160 0.068
oocyte anterior posterior axis specification GO:0007314 2 0.067
intracellular mrna localization GO:0008298 4 0.065
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.064
cellular amine metabolic process GO:0044106 44 0.063
maintenance of location GO:0051235 89 0.061
oocyte axis specification GO:0007309 2 0.059
ribonucleoside catabolic process GO:0042454 206 0.059
proteasomal protein catabolic process GO:0010498 98 0.056
Mouse Fly
nucleoside monophosphate metabolic process GO:0009123 85 0.054
purine nucleotide metabolic process GO:0006163 302 0.054
mrna processing GO:0006397 63 0.053
male gamete generation GO:0048232 285 0.053
Mouse
oocyte construction GO:0007308 2 0.052
cellular ketone metabolic process GO:0042180 84 0.052
modification dependent macromolecule catabolic process GO:0043632 133 0.051
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
hematopoietic progenitor cell differentiation GO:0002244 143 0.050
ubiquitin dependent protein catabolic process GO:0006511 129 0.050
Human Mouse Fly
maternal determination of anterior posterior axis embryo GO:0008358 2 0.049
nucleotide metabolic process GO:0009117 332 0.049
positive regulation of apoptotic process GO:0043065 217 0.048
Human
cellular response to dna damage stimulus GO:0006974 207 0.047
amine metabolic process GO:0009308 45 0.046
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.046
regulation of cellular catabolic process GO:0031329 242 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.042
cellular macromolecule catabolic process GO:0044265 206 0.041
Human Mouse Fly
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.041
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.041
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.039
protein processing GO:0016485 163 0.037
response to ionizing radiation GO:0010212 42 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.036
Human Mouse Fly
purine nucleoside monophosphate metabolic process GO:0009126 81 0.036
rna processing GO:0006396 105 0.035
mrna metabolic process GO:0016071 84 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
Human Mouse
glycosyl compound metabolic process GO:1901657 246 0.034
organelle assembly GO:0070925 177 0.034
cation transport GO:0006812 399 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
ribonucleoside monophosphate metabolic process GO:0009161 80 0.033
cellular amino acid metabolic process GO:0006520 103 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
nucleoside metabolic process GO:0009116 246 0.032
regulation of autophagy GO:0010506 30 0.032
regulation of cell division GO:0051302 76 0.031
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.031
mitotic cell cycle process GO:1903047 159 0.031
rhythmic process GO:0048511 174 0.031
centromere complex assembly GO:0034508 3 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
purine containing compound catabolic process GO:0072523 213 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
positive regulation of protein modification process GO:0031401 299 0.029
methylation GO:0032259 134 0.029
regulation of proteolysis GO:0030162 164 0.029
homeostasis of number of cells GO:0048872 210 0.029
regulation of protein kinase activity GO:0045859 232 0.028
nucleoside monophosphate catabolic process GO:0009125 59 0.028
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.028
ribonucleoprotein complex subunit organization GO:0071826 28 0.028
synaptic transmission GO:0007268 329 0.028
cellular homeostasis GO:0019725 240 0.027
response to light stimulus GO:0009416 135 0.027
protein catabolic process GO:0030163 221 0.026
Human Mouse Fly
microtubule polymerization or depolymerization GO:0031109 26 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
regulation of cell cycle phase transition GO:1901987 77 0.026
protein alkylation GO:0008213 81 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
cell cycle switching GO:0060184 1 0.026
positive regulation of cell death GO:0010942 224 0.026
Human
regulation of transferase activity GO:0051338 263 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
spliceosomal complex disassembly GO:0000390 1 0.025
peptidyl amino acid modification GO:0018193 336 0.025
nucleoside catabolic process GO:0009164 206 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
calcium ion transport GO:0006816 159 0.025
cell adhesion GO:0007155 329 0.025
lymphocyte differentiation GO:0030098 242 0.025
fatty acid metabolic process GO:0006631 121 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
macromolecule catabolic process GO:0009057 281 0.024
Human Mouse Fly
oocyte differentiation GO:0009994 35 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
establishment or maintenance of cell polarity GO:0007163 86 0.024
response to organonitrogen compound GO:0010243 246 0.023
response to organic cyclic compound GO:0014070 198 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
mrna splicing via spliceosome GO:0000398 43 0.023
negative regulation of fatty acid metabolic process GO:0045922 10 0.023
dephosphorylation GO:0016311 129 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
negative regulation of cellular senescence GO:2000773 3 0.022
macromolecule methylation GO:0043414 120 0.022
aromatic compound catabolic process GO:0019439 286 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
circadian rhythm GO:0007623 114 0.022
regulation of homeostatic process GO:0032844 182 0.022
female gamete generation GO:0007292 74 0.022
regulation of response to wounding GO:1903034 189 0.022
cell maturation GO:0048469 127 0.021
microtubule based process GO:0007017 236 0.021
negative regulation of cell cycle GO:0045786 123 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
negative regulation of cell size GO:0045792 3 0.021
cellular lipid metabolic process GO:0044255 323 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
oxidation reduction process GO:0055114 342 0.021
myotube differentiation GO:0014902 105 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.020
Mouse
negative regulation of cell cycle phase transition GO:1901988 48 0.020
divalent inorganic cation transport GO:0072511 178 0.020
cellular response to starvation GO:0009267 57 0.020
compound eye development GO:0048749 1 0.019
Fly
regulation of chromatin silencing GO:0031935 2 0.019
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
Human
megakaryocyte differentiation GO:0030219 26 0.019
glucose homeostasis GO:0042593 128 0.019
t cell activation GO:0042110 289 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
anatomical structure homeostasis GO:0060249 145 0.019
oocyte development GO:0048599 33 0.019
male meiosis GO:0007140 37 0.019
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
atp metabolic process GO:0046034 75 0.018
divalent metal ion transport GO:0070838 172 0.018
negative regulation of protein modification process GO:0031400 163 0.018
peptidyl lysine deacetylation GO:0034983 1 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
negative regulation of protein processing GO:0010955 79 0.018
lipid localization GO:0010876 126 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
carbohydrate homeostasis GO:0033500 128 0.018
cellular response to external stimulus GO:0071496 88 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
respiratory system development GO:0060541 190 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
myeloid cell homeostasis GO:0002262 114 0.017
erythrocyte differentiation GO:0030218 88 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
germ cell development GO:0007281 185 0.017
regulation of kinase activity GO:0043549 249 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.017
multi multicellular organism process GO:0044706 109 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of meiotic cell cycle GO:0051445 34 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
cellular protein complex assembly GO:0043623 116 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
rna splicing via transesterification reactions GO:0000375 43 0.016
regulation of cell size GO:0008361 72 0.016
establishment of organelle localization GO:0051656 122 0.016
regulation of organelle organization GO:0033043 289 0.016
calcium ion transmembrane transport GO:0070588 85 0.016
regulation of tor signaling GO:0032006 17 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
peptidyl lysine modification GO:0018205 77 0.016
cellular response to hormone stimulus GO:0032870 150 0.015
muscle cell differentiation GO:0042692 261 0.015
heart process GO:0003015 94 0.015
regulation of hydrolase activity GO:0051336 246 0.015
t cell differentiation GO:0030217 174 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
mitotic nuclear division GO:0007067 48 0.015
cation transmembrane transport GO:0098655 266 0.015
endocytosis GO:0006897 168 0.015
negative regulation of transferase activity GO:0051348 85 0.015
developmental maturation GO:0021700 193 0.015
sensory perception GO:0007600 245 0.015
cellular response to oxidative stress GO:0034599 76 0.015
histone modification GO:0016570 159 0.015
mitotic cell cycle GO:0000278 195 0.015
positive regulation of histone h3 k9 methylation GO:0051574 4 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of protein processing GO:0070613 96 0.015
atp catabolic process GO:0006200 55 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.014
ribonucleoprotein complex disassembly GO:0032988 3 0.014
cellular response to lipid GO:0071396 145 0.014
nucleus organization GO:0006997 45 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of protein maturation GO:1903317 96 0.014
cytosolic calcium ion homeostasis GO:0051480 70 0.014
striated muscle tissue development GO:0014706 293 0.014
cellular chemical homeostasis GO:0055082 215 0.014
regulation of double strand break repair via homologous recombination GO:0010569 2 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
regulation of transcription by chromatin organization GO:0034401 0 0.014
cellular response to radiation GO:0071478 28 0.014
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.014
membrane organization GO:0061024 245 0.013
purine containing compound metabolic process GO:0072521 311 0.013
sequestering of calcium ion GO:0051208 18 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
dna metabolic process GO:0006259 303 0.013
skeletal system development GO:0001501 356 0.013
microtubule nucleation GO:0007020 2 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
regulation of circadian rhythm GO:0042752 58 0.013
organic anion transport GO:0015711 137 0.013
response to testosterone GO:0033574 3 0.013
fat cell differentiation GO:0045444 160 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
Human Mouse Fly
mrna 3 end processing GO:0031124 16 0.013
b cell activation GO:0042113 161 0.013
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.012
gonad development GO:0008406 141 0.012
histone h3 k9 acetylation GO:0043970 5 0.012
negative regulation of tor signaling GO:0032007 13 0.012
lipid storage GO:0019915 36 0.012
covalent chromatin modification GO:0016569 163 0.012
response to oxidative stress GO:0006979 123 0.012
transmembrane transport GO:0055085 412 0.012
gene silencing GO:0016458 38 0.012
protein acylation GO:0043543 64 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
negative regulation of kinase activity GO:0033673 81 0.012
epithelial cell proliferation GO:0050673 174 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.012
regionalization GO:0003002 337 0.012
leukocyte apoptotic process GO:0071887 71 0.012
chromosome segregation GO:0007059 48 0.012
organophosphate catabolic process GO:0046434 232 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
innate immune response GO:0045087 157 0.012
spermatogenesis GO:0007283 284 0.012
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
dna repair GO:0006281 107 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
cell death in response to oxidative stress GO:0036473 24 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
regulation of system process GO:0044057 200 0.012
male sex differentiation GO:0046661 109 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
cilium assembly GO:0042384 81 0.011
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.011
positive regulation of transferase activity GO:0051347 167 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
ossification GO:0001503 216 0.011
microtubule polymerization GO:0046785 12 0.011
positive regulation of proteolysis GO:0045862 85 0.011
regulation of cell activation GO:0050865 289 0.011
dna templated transcription initiation GO:0006352 13 0.011
histone lysine methylation GO:0034968 50 0.011
nucleotide excision repair GO:0006289 13 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of protein catabolic process GO:0042176 108 0.011
segmentation GO:0035282 93 0.011
cellular response to acid chemical GO:0071229 68 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
protein localization to membrane GO:0072657 108 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of engulfment of apoptotic cell GO:1901074 2 0.011
regulation of feeding behavior GO:0060259 3 0.011
maturation of lsu rrna GO:0000470 1 0.011
cell division GO:0051301 120 0.011
protein oligomerization GO:0051259 67 0.011
response to inorganic substance GO:0010035 96 0.011
autophagy GO:0006914 45 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
substantia nigra development GO:0021762 2 0.010
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.010
cytoplasmic transport GO:0016482 234 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
wnt signaling pathway GO:0016055 188 0.010
placenta development GO:0001890 140 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
macromolecule deacylation GO:0098732 37 0.010
cellularization GO:0007349 1 0.010
muscle fiber development GO:0048747 76 0.010
sequestering of metal ion GO:0051238 19 0.010
protein methylation GO:0006479 81 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
tissue homeostasis GO:0001894 115 0.010
positive regulation of dna templated transcription elongation GO:0032786 2 0.010
protein deacylation GO:0035601 36 0.010
positive regulation of tor signaling GO:0032008 3 0.010

Siah1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.042
cancer DOID:162 0 0.031
organ system cancer DOID:0050686 0 0.031
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017