Mus musculus

44 known processes

H2-Bl

histocompatibility 2, blastocyst

(Aliases: H2-B1)

H2-Bl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.153
lipid biosynthetic process GO:0008610 179 0.139
oxidation reduction process GO:0055114 342 0.136
positive regulation of cytokine production GO:0001819 174 0.115
cellular ketone metabolic process GO:0042180 84 0.106
defense response to other organism GO:0098542 197 0.100
cellular lipid metabolic process GO:0044255 323 0.090
defense response to bacterium GO:0042742 119 0.088
cellular amino acid metabolic process GO:0006520 103 0.085
cytokine production GO:0001816 319 0.081
carbohydrate metabolic process GO:0005975 230 0.080
regulation of cellular ketone metabolic process GO:0010565 66 0.077
monocarboxylic acid metabolic process GO:0032787 191 0.076
lymphocyte mediated immunity GO:0002449 139 0.073
t cell activation GO:0042110 289 0.073
reactive nitrogen species metabolic process GO:2001057 0 0.072
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.070
reactive oxygen species metabolic process GO:0072593 84 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.069
reactive oxygen species biosynthetic process GO:1903409 8 0.065
response to organonitrogen compound GO:0010243 246 0.061
regulation of hydrolase activity GO:0051336 246 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
amine metabolic process GO:0009308 45 0.056
organic cyclic compound catabolic process GO:1901361 295 0.055
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.054
organonitrogen compound catabolic process GO:1901565 264 0.053
protein maturation GO:0051604 176 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
regulation of cytokine production GO:0001817 266 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.048
protein processing GO:0016485 163 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.047
regulation of endopeptidase activity GO:0052548 89 0.046
fatty acid metabolic process GO:0006631 121 0.046
adaptive immune response GO:0002250 155 0.046
nucleotide metabolic process GO:0009117 332 0.045
developmental maturation GO:0021700 193 0.045
interferon gamma production GO:0032609 67 0.044
antigen processing and presentation of peptide antigen GO:0048002 29 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
cellular amine metabolic process GO:0044106 44 0.043
ribonucleoside catabolic process GO:0042454 206 0.042
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.042
regulation of hormone levels GO:0010817 211 0.042
skeletal muscle organ development GO:0060538 163 0.041
sulfur compound metabolic process GO:0006790 100 0.040
gland development GO:0048732 330 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.039
immune effector process GO:0002252 321 0.038
cellular response to lipid GO:0071396 145 0.038
negative regulation of molecular function GO:0044092 258 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
purine containing compound catabolic process GO:0072523 213 0.037
regulation of lymphocyte mediated immunity GO:0002706 84 0.037
lipid catabolic process GO:0016042 69 0.036
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
regulation of cellular catabolic process GO:0031329 242 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
cation homeostasis GO:0055080 212 0.035
cellular response to biotic stimulus GO:0071216 92 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
heterocycle catabolic process GO:0046700 280 0.035
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.035
purine containing compound metabolic process GO:0072521 311 0.034
response to lipopolysaccharide GO:0032496 128 0.034
mitochondrion organization GO:0007005 134 0.033
response to organic cyclic compound GO:0014070 198 0.033
negative regulation of hydrolase activity GO:0051346 71 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
macromolecule catabolic process GO:0009057 281 0.033
leukocyte mediated cytotoxicity GO:0001909 62 0.033
organic acid biosynthetic process GO:0016053 86 0.032
regulation of cell killing GO:0031341 40 0.032
monosaccharide metabolic process GO:0005996 106 0.032
peptidyl amino acid modification GO:0018193 336 0.031
epithelial cell proliferation GO:0050673 174 0.029
regulation of peptidase activity GO:0052547 96 0.029
regulation of interferon gamma production GO:0032649 57 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
myotube differentiation GO:0014902 105 0.029
regulation of cell activation GO:0050865 289 0.029
striated muscle cell development GO:0055002 125 0.029
positive regulation of immune effector process GO:0002699 107 0.028
hexose metabolic process GO:0019318 98 0.028
guanosine containing compound metabolic process GO:1901068 144 0.028
response to peptide GO:1901652 136 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
rho protein signal transduction GO:0007266 32 0.028
fat soluble vitamin biosynthetic process GO:0042362 4 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
innate immune response GO:0045087 157 0.028
interspecies interaction between organisms GO:0044419 83 0.028
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
regulation of proteolysis GO:0030162 164 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
cell activation involved in immune response GO:0002263 126 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
myeloid cell differentiation GO:0030099 233 0.025
response to peptide hormone GO:0043434 127 0.025
nucleoside catabolic process GO:0009164 206 0.025
muscle cell development GO:0055001 133 0.025
positive regulation of leukocyte mediated immunity GO:0002705 70 0.025
peptidyl tyrosine phosphorylation GO:0018108 143 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
muscle fiber development GO:0048747 76 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
defense response to gram positive bacterium GO:0050830 50 0.025
regulation of skeletal muscle fiber development GO:0048742 36 0.025
regulation of t cell mediated cytotoxicity GO:0001914 18 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
aromatic compound catabolic process GO:0019439 286 0.024
response to inorganic substance GO:0010035 96 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
cation transport GO:0006812 399 0.024
purine nucleotide metabolic process GO:0006163 302 0.023
nucleotide catabolic process GO:0009166 217 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
regulation of defense response GO:0031347 233 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
striated muscle tissue development GO:0014706 293 0.023
regulation of leukocyte mediated immunity GO:0002703 104 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
positive regulation of interferon gamma production GO:0032729 39 0.023
leukocyte activation involved in immune response GO:0002366 126 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
leukocyte mediated immunity GO:0002443 174 0.022
skeletal muscle fiber development GO:0048741 58 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
positive regulation of kinase activity GO:0033674 155 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
cell killing GO:0001906 67 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
cellular response to peptide GO:1901653 92 0.022
regulation of system process GO:0044057 200 0.022
ear development GO:0043583 200 0.022
glucose homeostasis GO:0042593 128 0.021
nucleoside metabolic process GO:0009116 246 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
regulation of protein processing GO:0070613 96 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cell maturation GO:0048469 127 0.021
ras protein signal transduction GO:0007265 77 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
positive regulation of protein modification process GO:0031401 299 0.021
regulation of establishment of protein localization GO:0070201 181 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
antigen processing and presentation GO:0019882 47 0.020
hormone secretion GO:0046879 128 0.020
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.020
small molecule catabolic process GO:0044282 71 0.020
synaptic transmission GO:0007268 329 0.020
sensory perception GO:0007600 245 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
blood vessel morphogenesis GO:0048514 285 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
steroid metabolic process GO:0008202 119 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
cell type specific apoptotic process GO:0097285 268 0.019
alcohol metabolic process GO:0006066 116 0.019
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.019
regulation of organelle organization GO:0033043 289 0.018
negative regulation of endopeptidase activity GO:0010951 44 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
circulatory system process GO:0003013 197 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
glucose metabolic process GO:0006006 92 0.018
cofactor metabolic process GO:0051186 80 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
natural killer cell mediated immunity GO:0002228 29 0.018
regulation of lipid biosynthetic process GO:0046890 54 0.018
organophosphate catabolic process GO:0046434 232 0.018
oocyte axis specification GO:0007309 2 0.018
carbohydrate biosynthetic process GO:0016051 74 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
endocytosis GO:0006897 168 0.018
leukocyte differentiation GO:0002521 342 0.017
regulation of ossification GO:0030278 112 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
biomineral tissue development GO:0031214 64 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
regulation of cellular response to stress GO:0080135 159 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
compound eye development GO:0048749 1 0.017
microtubule based process GO:0007017 236 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.017
maintenance of location GO:0051235 89 0.017
muscle tissue development GO:0060537 308 0.017
positive regulation of transferase activity GO:0051347 167 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
positive regulation of adaptive immune response GO:0002821 61 0.017
cellular polysaccharide metabolic process GO:0044264 38 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.016
cellular response to cadmium ion GO:0071276 3 0.016
response to steroid hormone GO:0048545 56 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
myotube cell development GO:0014904 60 0.016
calcium ion homeostasis GO:0055074 127 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of protein maturation GO:1903317 96 0.016
positive regulation of cell death GO:0010942 224 0.016
response to acid chemical GO:0001101 111 0.016
cellular macromolecule catabolic process GO:0044265 206 0.015
protein catabolic process GO:0030163 221 0.015
small molecule biosynthetic process GO:0044283 132 0.015
intracellular protein transport GO:0006886 204 0.015
cellular response to steroid hormone stimulus GO:0071383 33 0.015
energy reserve metabolic process GO:0006112 39 0.015
peptide metabolic process GO:0006518 46 0.015
regulation of adaptive immune response GO:0002819 90 0.015
positive regulation of cell killing GO:0031343 33 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of anatomical structure size GO:0090066 178 0.015
hair follicle development GO:0001942 85 0.015
cellular amide metabolic process GO:0043603 58 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
cell adhesion GO:0007155 329 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
ossification GO:0001503 216 0.014
extracellular matrix organization GO:0030198 147 0.014
glucan metabolic process GO:0044042 32 0.014
dephosphorylation GO:0016311 129 0.014
t cell mediated immunity GO:0002456 50 0.014
gtp metabolic process GO:0046039 144 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
leukocyte proliferation GO:0070661 172 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
cellular homeostasis GO:0019725 240 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.013
response to phenylpropanoid GO:0080184 22 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
inflammatory response GO:0006954 244 0.013
regulation of protein localization GO:0032880 231 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
germ cell development GO:0007281 185 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
dna metabolic process GO:0006259 303 0.013
protein localization to nucleus GO:0034504 121 0.013
negative regulation of lipid metabolic process GO:0045833 30 0.013
negative regulation of proteolysis GO:0045861 74 0.013
cellular alcohol metabolic process GO:0044107 3 0.013
response to protozoan GO:0001562 28 0.013
glycoprotein metabolic process GO:0009100 116 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
response to oxidative stress GO:0006979 123 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of transferase activity GO:0051338 263 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
protein oligomerization GO:0051259 67 0.013
carbohydrate homeostasis GO:0033500 128 0.013
neutral lipid metabolic process GO:0006638 57 0.013
organic hydroxy compound biosynthetic process GO:1901617 77 0.013
nuclear transport GO:0051169 139 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
spermatogenesis GO:0007283 284 0.013
organic acid catabolic process GO:0016054 51 0.013
cytokine production involved in immune response GO:0002367 34 0.013
interleukin 1 beta production GO:0032611 30 0.012
regulation of mapk cascade GO:0043408 248 0.012
tissue homeostasis GO:0001894 115 0.012
positive regulation of cell activation GO:0050867 158 0.012
cellularization GO:0007349 1 0.012
cellular response to acid chemical GO:0071229 68 0.012
regulation of peptide secretion GO:0002791 77 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
interleukin 8 production GO:0032637 4 0.012
protein targeting GO:0006605 143 0.012
organ regeneration GO:0031100 2 0.012
regeneration GO:0031099 38 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.012
homeostasis of number of cells GO:0048872 210 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
response to nutrient levels GO:0031667 109 0.012
phagocytosis GO:0006909 66 0.012
lymphocyte proliferation GO:0046651 164 0.012
membrane organization GO:0061024 245 0.012
limb morphogenesis GO:0035108 149 0.012
regulation of kinase activity GO:0043549 249 0.012
appendage development GO:0048736 166 0.012
defense response to virus GO:0051607 68 0.012
positive regulation of lipid transport GO:0032370 22 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of muscle tissue development GO:1901861 97 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
response to stilbenoid GO:0035634 22 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
transition metal ion transport GO:0000041 38 0.012
multicellular organismal signaling GO:0035637 91 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
polysaccharide metabolic process GO:0005976 39 0.012
regulation of membrane potential GO:0042391 192 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
unsaturated fatty acid metabolic process GO:0033559 31 0.011
oocyte construction GO:0007308 2 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
epidermis development GO:0008544 187 0.011
defense response to gram negative bacterium GO:0050829 28 0.011
iron ion import into cell GO:0097459 4 0.011
neural tube development GO:0021915 160 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
transmembrane transport GO:0055085 412 0.011
t cell mediated cytotoxicity GO:0001913 26 0.011
anion transport GO:0006820 177 0.011
calcitriol biosynthetic process from calciol GO:0036378 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of response to biotic stimulus GO:0002831 38 0.011
skin development GO:0043588 220 0.011
blood circulation GO:0008015 195 0.011
lipid localization GO:0010876 126 0.011
apoptotic signaling pathway GO:0097190 306 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
regulation of binding GO:0051098 111 0.011
regulation of cell cycle GO:0051726 281 0.011
glycerolipid metabolic process GO:0046486 122 0.011
protein ubiquitination GO:0016567 171 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
protein import GO:0017038 101 0.011
regulation of blood pressure GO:0008217 93 0.011
carboxylic acid transport GO:0046942 100 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
cellular ion homeostasis GO:0006873 165 0.011
cofactor transport GO:0051181 4 0.011
hexose biosynthetic process GO:0019319 39 0.011
immunoglobulin mediated immune response GO:0016064 69 0.011
negative regulation of protein processing GO:0010955 79 0.011
cell substrate adhesion GO:0031589 130 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of t cell mediated immunity GO:0002709 34 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
action potential GO:0001508 78 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
negative regulation of epithelial cell proliferation GO:0050680 64 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
multi multicellular organism process GO:0044706 109 0.010
glycogen metabolic process GO:0005977 32 0.010
neuron death GO:0070997 154 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
protein homooligomerization GO:0051260 43 0.010
positive regulation of stress activated mapk cascade GO:0032874 48 0.010
cellular protein catabolic process GO:0044257 155 0.010
positive regulation of endocytosis GO:0045807 42 0.010
learning or memory GO:0007611 148 0.010
alpha beta t cell activation GO:0046631 91 0.010
hormone biosynthetic process GO:0042446 16 0.010
thermosensory behavior GO:0040040 1 0.010
negative regulation of protein modification process GO:0031400 163 0.010
establishment of protein localization to organelle GO:0072594 118 0.010

H2-Bl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
bone disease DOID:0080001 0 0.015
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011
nervous system disease DOID:863 0 0.011