Mus musculus

34 known processes

A1cf

APOBEC1 complementation factor

(Aliases: Acf,ASP,ACF65,1810073H04Rik,ACF64)

A1cf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
naphthalene metabolic process GO:0018931 1 0.272
fat soluble vitamin biosynthetic process GO:0042362 4 0.110
naphthalene containing compound metabolic process GO:0090420 1 0.087
activation of immune response GO:0002253 138 0.086
regulation of secretion GO:0051046 274 0.076
organic anion transport GO:0015711 137 0.071
innate immune response GO:0045087 157 0.069
lipid biosynthetic process GO:0008610 179 0.067
cellular lipid metabolic process GO:0044255 323 0.066
monocarboxylic acid metabolic process GO:0032787 191 0.065
anion transport GO:0006820 177 0.065
vitamin d3 metabolic process GO:0070640 3 0.063
calcitriol biosynthetic process from calciol GO:0036378 3 0.060
organic acid transport GO:0015849 101 0.058
apoptotic signaling pathway GO:0097190 306 0.057
alcohol metabolic process GO:0006066 116 0.057
cellular alcohol biosynthetic process GO:0044108 3 0.056
cellular amino acid metabolic process GO:0006520 103 0.056
maintenance of location GO:0051235 89 0.051
uronic acid metabolic process GO:0006063 2 0.050
immune response regulating signaling pathway GO:0002764 125 0.049
cellular ketone metabolic process GO:0042180 84 0.048
organic hydroxy compound metabolic process GO:1901615 203 0.047
negative regulation of immune system process GO:0002683 209 0.047
glycoprotein biosynthetic process GO:0009101 89 0.046
cytokine production GO:0001816 319 0.044
immune effector process GO:0002252 321 0.044
short chain fatty acid catabolic process GO:0019626 2 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
carbohydrate metabolic process GO:0005975 230 0.043
cellular alcohol metabolic process GO:0044107 3 0.042
immune response activating signal transduction GO:0002757 116 0.042
cellular amine metabolic process GO:0044106 44 0.041
vitamin d biosynthetic process GO:0042368 3 0.040
cation transport GO:0006812 399 0.040
secondary alcohol metabolic process GO:1902652 3 0.040
regulation of cytokine production GO:0001817 266 0.040
small molecule biosynthetic process GO:0044283 132 0.039
response to peptide hormone GO:0043434 127 0.038
fatty acid derivative metabolic process GO:1901568 33 0.037
lipid localization GO:0010876 126 0.036
positive regulation of antimicrobial peptide production GO:0002225 1 0.034
glycoprotein metabolic process GO:0009100 116 0.034
regulation of cell activation GO:0050865 289 0.033
alcohol biosynthetic process GO:0046165 43 0.033
positive regulation of defense response GO:0031349 124 0.033
steroid metabolic process GO:0008202 119 0.033
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.032
organelle assembly GO:0070925 177 0.032
response to inorganic substance GO:0010035 96 0.032
regulation of defense response GO:0031347 233 0.032
carboxylic acid transport GO:0046942 100 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
lipid transport GO:0006869 98 0.030
positive regulation of innate immune response GO:0045089 80 0.030
protein glycosylation GO:0006486 55 0.030
cofactor metabolic process GO:0051186 80 0.030
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.029
extrinsic apoptotic signaling pathway GO:0097191 126 0.029
transmembrane transport GO:0055085 412 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
striated muscle myosin thick filament assembly GO:0071688 1 0.028
oxidation reduction process GO:0055114 342 0.028
fatty acid metabolic process GO:0006631 121 0.028
regulation of secretion by cell GO:1903530 249 0.027
nitrogen compound transport GO:0071705 271 0.027
myosin filament organization GO:0031033 3 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
sulfur compound metabolic process GO:0006790 100 0.025
t cell activation GO:0042110 289 0.025
myosin filament assembly GO:0031034 2 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
antimicrobial peptide production GO:0002775 2 0.025
leukocyte activation involved in immune response GO:0002366 126 0.024
leukocyte differentiation GO:0002521 342 0.024
regulation of hormone levels GO:0010817 211 0.024
response to organic cyclic compound GO:0014070 198 0.024
regulation of t cell activation GO:0050863 170 0.024
cellular ion homeostasis GO:0006873 165 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
regulation of multi organism process GO:0043900 111 0.024
purine containing compound metabolic process GO:0072521 311 0.024
regulation of body fluid levels GO:0050878 162 0.024
macromolecule glycosylation GO:0043413 55 0.024
response to peptide GO:1901652 136 0.024
divalent inorganic cation transport GO:0072511 178 0.024
protein ubiquitination GO:0016567 171 0.024
monocarboxylic acid transport GO:0015718 44 0.023
regulation of feeding behavior GO:0060259 3 0.022
regulation of innate immune response GO:0045088 91 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
sensory perception GO:0007600 245 0.022
peptidyl amino acid modification GO:0018193 336 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
glucuronate metabolic process GO:0019585 2 0.022
icosanoid metabolic process GO:0006690 33 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
regulation of cell motility GO:2000145 236 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
ribonucleotide metabolic process GO:0009259 291 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
unsaturated fatty acid metabolic process GO:0033559 31 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
regulation of antimicrobial humoral response GO:0002759 3 0.021
cellular response to inorganic substance GO:0071241 37 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
response to lipopolysaccharide GO:0032496 128 0.020
response to radiation GO:0009314 165 0.020
cation transmembrane transport GO:0098655 266 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
chemotaxis GO:0006935 247 0.020
mitotic cell cycle GO:0000278 195 0.020
endomembrane system organization GO:0010256 147 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
organophosphate catabolic process GO:0046434 232 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
myeloid cell differentiation GO:0030099 233 0.019
cell activation involved in immune response GO:0002263 126 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
defense response to bacterium GO:0042742 119 0.019
lipid catabolic process GO:0016042 69 0.019
actin cytoskeleton organization GO:0030036 220 0.019
positive regulation of secretion GO:0051047 130 0.018
cellular response to peptide hormone stimulus GO:0071375 92 0.018
cytoplasmic transport GO:0016482 234 0.018
cellular response to molecule of bacterial origin GO:0071219 83 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
regulation of organelle organization GO:0033043 289 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
cellular protein complex assembly GO:0043623 116 0.018
nucleotide metabolic process GO:0009117 332 0.018
divalent metal ion transport GO:0070838 172 0.018
establishment of blood nerve barrier GO:0008065 3 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
negative regulation of immune effector process GO:0002698 55 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
cellular response to cadmium ion GO:0071276 3 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
Mouse
inter male aggressive behavior GO:0002121 3 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
leukocyte proliferation GO:0070661 172 0.017
membrane organization GO:0061024 245 0.017
glycerolipid metabolic process GO:0046486 122 0.017
axonogenesis GO:0007409 274 0.017
cellular lipid catabolic process GO:0044242 52 0.017
aromatic compound catabolic process GO:0019439 286 0.016
response to acid chemical GO:0001101 111 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
organic hydroxy compound biosynthetic process GO:1901617 77 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
humoral immune response GO:0006959 57 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
lymphocyte differentiation GO:0030098 242 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
signal transduction in absence of ligand GO:0038034 55 0.016
anion transmembrane transport GO:0098656 71 0.016
polyol metabolic process GO:0019751 26 0.016
cytokine biosynthetic process GO:0042089 68 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
coenzyme metabolic process GO:0006732 52 0.016
inflammatory response GO:0006954 244 0.016
oxidative demethylation GO:0070989 1 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
epithelial cell development GO:0002064 159 0.015
positive regulation of immune effector process GO:0002699 107 0.015
activation of mapk activity involved in innate immune response GO:0035419 2 0.015
cellular homeostasis GO:0019725 240 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
mitotic cell cycle process GO:1903047 159 0.015
regulation of cell cycle GO:0051726 281 0.015
cellular response to peptide GO:1901653 92 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
regulation of intracellular transport GO:0032386 159 0.015
organelle fission GO:0048285 170 0.015
wound healing GO:0042060 157 0.015
leukocyte migration GO:0050900 124 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.014
cellular chemical homeostasis GO:0055082 215 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
regulation of protein localization GO:0032880 231 0.014
keratinocyte differentiation GO:0030216 48 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
male gamete generation GO:0048232 285 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
lymphocyte proliferation GO:0046651 164 0.014
t cell receptor signaling pathway GO:0050852 46 0.014
cell adhesion GO:0007155 329 0.014
camera type eye development GO:0043010 266 0.014
innate immune response activating signal transduction GO:0002758 50 0.014
myeloid leukocyte activation GO:0002274 83 0.014
regulation of cytokine biosynthetic process GO:0042035 59 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
cartilage development GO:0051216 140 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.013
response to light stimulus GO:0009416 135 0.013
response to insulin GO:0032868 100 0.013
establishment of organelle localization GO:0051656 122 0.013
bile acid and bile salt transport GO:0015721 5 0.013
angiogenesis GO:0001525 201 0.013
negative regulation of protein modification process GO:0031400 163 0.013
muscle cell differentiation GO:0042692 261 0.013
regulation of response to biotic stimulus GO:0002831 38 0.013
peptide metabolic process GO:0006518 46 0.013
glycosylation GO:0070085 62 0.013
respiratory tube development GO:0030323 167 0.013
amine metabolic process GO:0009308 45 0.013
cell growth GO:0016049 130 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
activation of innate immune response GO:0002218 56 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
antibacterial peptide biosynthetic process GO:0002780 2 0.013
response to drug GO:0042493 75 0.013
protein processing GO:0016485 163 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
nucleoside catabolic process GO:0009164 206 0.013
response to growth factor GO:0070848 198 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
t cell proliferation GO:0042098 120 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
hormone secretion GO:0046879 128 0.012
organelle localization GO:0051640 179 0.012
ras protein signal transduction GO:0007265 77 0.012
positive regulation of interferon alpha production GO:0032727 4 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cellular protein catabolic process GO:0044257 155 0.012
protein localization to membrane GO:0072657 108 0.012
vitamin metabolic process GO:0006766 23 0.012
dephosphorylation GO:0016311 129 0.012
membrane lipid metabolic process GO:0006643 53 0.012
nuclear division GO:0000280 158 0.012
fat soluble vitamin metabolic process GO:0006775 11 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
negative regulation of defense response GO:0031348 77 0.012
regulation of anatomical structure size GO:0090066 178 0.012
sensory organ morphogenesis GO:0090596 242 0.012
response to organonitrogen compound GO:0010243 246 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
homeostasis of number of cells GO:0048872 210 0.012
protein localization to organelle GO:0033365 185 0.012
cytokine metabolic process GO:0042107 71 0.012
protein catabolic process GO:0030163 221 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
plasma membrane organization GO:0007009 90 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
negative regulation of cell activation GO:0050866 111 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
regulation of protein transport GO:0051223 163 0.011
positive regulation of antimicrobial humoral response GO:0002760 2 0.011
positive regulation of proteolysis GO:0045862 85 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
lipid storage GO:0019915 36 0.011
positive regulation of cytokine production GO:0001819 174 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
nucleoside metabolic process GO:0009116 246 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
cation homeostasis GO:0055080 212 0.011
antigen receptor mediated signaling pathway GO:0050851 64 0.011
epithelial cell proliferation GO:0050673 174 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
macromolecule catabolic process GO:0009057 281 0.011
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
monocyte extravasation GO:0035696 2 0.011
photoreceptor cell differentiation GO:0046530 52 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
positive regulation of cell activation GO:0050867 158 0.011
long chain fatty acid metabolic process GO:0001676 26 0.011
cellular response to lipid GO:0071396 145 0.011
glial cell apoptotic process GO:0034349 3 0.011
digestive system development GO:0055123 200 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
linoleic acid metabolic process GO:0043651 6 0.011
regulation of response to wounding GO:1903034 189 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
methionine transport GO:0015821 1 0.011
positive regulation of cell death GO:0010942 224 0.011
intracellular protein transport GO:0006886 204 0.011
negative regulation of macrophage apoptotic process GO:2000110 3 0.011
leukocyte mediated immunity GO:0002443 174 0.011
calcium mediated signaling GO:0019722 46 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
protein kinase b signaling GO:0043491 74 0.011
regulation of ion transport GO:0043269 215 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
gliogenesis GO:0042063 141 0.011
ion transmembrane transport GO:0034220 361 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
regulation of system process GO:0044057 200 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
metal ion homeostasis GO:0055065 189 0.010
protein polymerization GO:0051258 57 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
positive regulation of hormone secretion GO:0046887 38 0.010
sequestering of calcium ion GO:0051208 18 0.010
interleukin 8 production GO:0032637 4 0.010
pharynx development GO:0060465 1 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
rho protein signal transduction GO:0007266 32 0.010
defense response to other organism GO:0098542 197 0.010
mitochondrion organization GO:0007005 134 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
wnt signaling pathway GO:0016055 188 0.010
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.010
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
regulation of viral transcription GO:0046782 3 0.010
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.010
regulation of monocyte extravasation GO:2000437 2 0.010
atp metabolic process GO:0046034 75 0.010
nucleotide catabolic process GO:0009166 217 0.010
modification by symbiont of host morphology or physiology GO:0044003 4 0.010
regulation of humoral immune response GO:0002920 22 0.010

A1cf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.053
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
inherited metabolic disorder DOID:655 0 0.028
immune system disease DOID:2914 0 0.027
lipid metabolism disorder DOID:3146 0 0.020
organ system cancer DOID:0050686 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
sensory system disease DOID:0050155 0 0.013
hematopoietic system disease DOID:74 0 0.013
diabetes mellitus DOID:9351 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
type 2 diabetes mellitus DOID:9352 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
glucose metabolism disease DOID:4194 0 0.012
eye disease DOID:5614 0 0.012
eye and adnexa disease DOID:1492 0 0.012