Mus musculus

141 known processes

Aars

alanyl-tRNA synthetase

(Aliases: MGC37368,C76919,AI316495,sti)

Aars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 1 0.816
trna aminoacylation for protein translation GO:0006418 1 0.694
trna metabolic process GO:0006399 11 0.421
cellular amino acid metabolic process GO:0006520 103 0.352
translation GO:0006412 93 0.164
nucleobase containing small molecule metabolic process GO:0055086 352 0.116
ribonucleoside triphosphate catabolic process GO:0009203 199 0.090
cellular amine metabolic process GO:0044106 44 0.088
nucleoside triphosphate metabolic process GO:0009141 230 0.087
purine nucleoside triphosphate catabolic process GO:0009146 203 0.082
protein modification by small protein conjugation or removal GO:0070647 207 0.080
nucleotide metabolic process GO:0009117 332 0.078
cytoplasmic translational initiation GO:0002183 3 0.074
trna aminoacylation GO:0043039 1 0.073
regulation of cellular amine metabolic process GO:0033238 20 0.065
ribonucleotide catabolic process GO:0009261 208 0.062
gonad development GO:0008406 141 0.060
organonitrogen compound catabolic process GO:1901565 264 0.057
purine ribonucleoside metabolic process GO:0046128 241 0.057
purine containing compound catabolic process GO:0072523 213 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
purine containing compound metabolic process GO:0072521 311 0.056
modification dependent macromolecule catabolic process GO:0043632 133 0.055
ribose phosphate metabolic process GO:0019693 291 0.054
purine nucleoside metabolic process GO:0042278 241 0.054
cellular protein catabolic process GO:0044257 155 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
carbohydrate metabolic process GO:0005975 230 0.047
heterocycle catabolic process GO:0046700 280 0.047
positive regulation of cellular catabolic process GO:0031331 148 0.046
male gamete generation GO:0048232 285 0.046
ribonucleoside monophosphate catabolic process GO:0009158 57 0.044
amine metabolic process GO:0009308 45 0.044
carbohydrate derivative catabolic process GO:1901136 231 0.044
carbohydrate biosynthetic process GO:0016051 74 0.043
dna metabolic process GO:0006259 303 0.043
negative regulation of protein metabolic process GO:0051248 282 0.043
glycosyl compound catabolic process GO:1901658 206 0.043
protein modification by small protein conjugation GO:0032446 187 0.041
ribonucleoside metabolic process GO:0009119 245 0.040
cellular ketone metabolic process GO:0042180 84 0.040
glucose metabolic process GO:0006006 92 0.039
cristae formation GO:0042407 3 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
nucleoside catabolic process GO:0009164 206 0.036
response to endoplasmic reticulum stress GO:0034976 53 0.036
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
regulation of cellular response to oxidative stress GO:1900407 19 0.034
monosaccharide metabolic process GO:0005996 106 0.034
macromolecule catabolic process GO:0009057 281 0.033
positive regulation of protein modification process GO:0031401 299 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
protein ubiquitination GO:0016567 171 0.032
spermatogenesis GO:0007283 284 0.032
hexose biosynthetic process GO:0019319 39 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
regulation of translation GO:0006417 71 0.032
aromatic compound catabolic process GO:0019439 286 0.031
neuron apoptotic process GO:0051402 142 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
rhythmic process GO:0048511 174 0.030
organophosphate catabolic process GO:0046434 232 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
multicellular organism growth GO:0035264 161 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
purine nucleoside catabolic process GO:0006152 205 0.028
sensory organ morphogenesis GO:0090596 242 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
cytokine production GO:0001816 319 0.028
hexose metabolic process GO:0019318 98 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
spermatid differentiation GO:0048515 115 0.026
development of primary sexual characteristics GO:0045137 143 0.026
ion transmembrane transport GO:0034220 361 0.026
mitotic cell cycle GO:0000278 195 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
negative regulation of molecular function GO:0044092 258 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
lymphocyte differentiation GO:0030098 242 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of cell cycle GO:0051726 281 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
membrane organization GO:0061024 245 0.023
gland development GO:0048732 330 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
oligosaccharide catabolic process GO:0009313 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
stem cell differentiation GO:0048863 268 0.022
nucleoside metabolic process GO:0009116 246 0.022
response to extracellular stimulus GO:0009991 127 0.022
translational initiation GO:0006413 24 0.022
methionine transport GO:0015821 1 0.022
endocytosis GO:0006897 168 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
blastocyst development GO:0001824 80 0.021
metal ion homeostasis GO:0055065 189 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
cell type specific apoptotic process GO:0097285 268 0.020
protein catabolic process GO:0030163 221 0.020
maintenance of location GO:0051235 89 0.020
nucleoside monophosphate catabolic process GO:0009125 59 0.020
cellular response to external stimulus GO:0071496 88 0.020
modification dependent protein catabolic process GO:0019941 133 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
cellular lipid metabolic process GO:0044255 323 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.019
development of primary female sexual characteristics GO:0046545 73 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
atp catabolic process GO:0006200 55 0.019
nucleotide catabolic process GO:0009166 217 0.019
attachment of spindle microtubules to kinetochore GO:0008608 4 0.019
camera type eye development GO:0043010 266 0.019
ovarian follicle development GO:0001541 40 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
protein targeting GO:0006605 143 0.018
regulation of cell activation GO:0050865 289 0.018
spermatid development GO:0007286 108 0.018
rna interference GO:0016246 2 0.018
divalent metal ion transport GO:0070838 172 0.018
connective tissue development GO:0061448 179 0.017
inclusion body assembly GO:0070841 3 0.017
folic acid containing compound metabolic process GO:0006760 3 0.017
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.017
negative regulation of neuron death GO:1901215 98 0.017
protein localization to organelle GO:0033365 185 0.017
transmembrane transport GO:0055085 412 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
branched chain amino acid transport GO:0015803 2 0.017
leukocyte differentiation GO:0002521 342 0.017
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.017
gluconeogenesis GO:0006094 39 0.017
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.016
regulation of transferase activity GO:0051338 263 0.016
neuron death GO:0070997 154 0.016
circadian regulation of gene expression GO:0032922 48 0.016
anion transmembrane transport GO:0098656 71 0.016
cation transmembrane transport GO:0098655 266 0.016
forebrain development GO:0030900 302 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of organelle organization GO:0033043 289 0.016
response to organic cyclic compound GO:0014070 198 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
cellular chemical homeostasis GO:0055082 215 0.016
female sex differentiation GO:0046660 84 0.016
monosaccharide biosynthetic process GO:0046364 44 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cellular homeostasis GO:0019725 240 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
muscle cell differentiation GO:0042692 261 0.015
t cell activation GO:0042110 289 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.015
carboxylic acid catabolic process GO:0046395 51 0.015
ras protein signal transduction GO:0007265 77 0.015
liver development GO:0001889 66 0.015
skeletal system development GO:0001501 356 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
response to acid chemical GO:0001101 111 0.014
pentose phosphate shunt GO:0006098 2 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
carbohydrate catabolic process GO:0016052 32 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
cation homeostasis GO:0055080 212 0.014
nuclear import GO:0051170 95 0.014
calcium ion homeostasis GO:0055074 127 0.014
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
organic acid transport GO:0015849 101 0.014
disaccharide metabolic process GO:0005984 1 0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
positive regulation of cell death GO:0010942 224 0.013
cellular protein complex assembly GO:0043623 116 0.013
positive regulation of cell development GO:0010720 237 0.013
apoptotic signaling pathway GO:0097190 306 0.013
small molecule biosynthetic process GO:0044283 132 0.013
response to nutrient levels GO:0031667 109 0.013
lung development GO:0030324 164 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
organic cyclic compound catabolic process GO:1901361 295 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
sulfur amino acid transport GO:0000101 2 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
polyamine biosynthetic process GO:0006596 2 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
cellular amide metabolic process GO:0043603 58 0.012
response to organonitrogen compound GO:0010243 246 0.012
maturation of 5 8s rrna GO:0000460 1 0.012
stem cell development GO:0048864 219 0.012
fertilization GO:0009566 127 0.012
regulation of mapk cascade GO:0043408 248 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
protein maturation GO:0051604 176 0.011
regulation of protein catabolic process GO:0042176 108 0.011
chromatin organization GO:0006325 206 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of protein kinase activity GO:0045859 232 0.011
respiratory tube development GO:0030323 167 0.011
telencephalon development GO:0021537 186 0.011
phospholipid metabolic process GO:0006644 87 0.011
germ cell development GO:0007281 185 0.011
Worm
protein polymerization GO:0051258 57 0.011
renal system development GO:0072001 225 0.011
respiratory system development GO:0060541 190 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
anion transport GO:0006820 177 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
nadph regeneration GO:0006740 2 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
microtubule based process GO:0007017 236 0.011
macromolecular complex disassembly GO:0032984 43 0.011
amino acid transmembrane transport GO:0003333 37 0.011
nuclear transport GO:0051169 139 0.010
intracellular protein transport GO:0006886 204 0.010
cation transport GO:0006812 399 0.010
circadian rhythm GO:0007623 114 0.010
ossification GO:0001503 216 0.010
hepaticobiliary system development GO:0061008 67 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
cellular response to lipid GO:0071396 145 0.010
transmission of nerve impulse GO:0019226 76 0.010
response to inorganic substance GO:0010035 96 0.010
gtp catabolic process GO:0006184 143 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.010
regulation of cytokine production GO:0001817 266 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
wnt signaling pathway GO:0016055 188 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
response to peptide GO:1901652 136 0.010
cell adhesion GO:0007155 329 0.010
epithelial cell development GO:0002064 159 0.010
regulation of neuron projection development GO:0010975 169 0.010

Aars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuropathy DOID:870 0 0.502
Human
nervous system disease DOID:863 0 0.502
Human
disease of anatomical entity DOID:7 0 0.502
Human
neuromuscular disease DOID:440 0 0.390
Human
charcot marie tooth disease type 2 DOID:0050539 0 0.385
Human
charcot marie tooth disease DOID:10595 0 0.385
Human
central nervous system disease DOID:331 0 0.077
neurodegenerative disease DOID:1289 0 0.033
sensory system disease DOID:0050155 0 0.016
eye disease DOID:5614 0 0.013
eye and adnexa disease DOID:1492 0 0.013
retinal degeneration DOID:8466 0 0.013
retinal disease DOID:5679 0 0.013