Mus musculus

111 known processes

Abca1

ATP-binding cassette, sub-family A (ABC1), member 1

(Aliases: Abc1)

Abca1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reverse cholesterol transport GO:0043691 6 1.000
regulation of sterol transport GO:0032371 17 0.999
positive regulation of sterol transport GO:0032373 9 0.999
protein lipid complex subunit organization GO:0071825 12 0.999
Human
cholesterol homeostasis GO:0042632 44 0.997
Human
phospholipid transport GO:0015914 21 0.996
sterol homeostasis GO:0055092 45 0.996
Human
lipid homeostasis GO:0055088 63 0.996
Human Mouse
sterol metabolic process GO:0016125 58 0.995
sterol transport GO:0015918 38 0.995
plasma lipoprotein particle remodeling GO:0034369 6 0.994
intracellular cholesterol transport GO:0032367 3 0.994
Human
cholesterol transport GO:0030301 38 0.991
organophosphate ester transport GO:0015748 28 0.989
regulation of cholesterol transport GO:0032374 17 0.988
cholesterol efflux GO:0033344 24 0.988
plasma lipoprotein particle organization GO:0071827 11 0.981
Human
positive regulation of cholesterol transport GO:0032376 9 0.981
regulation of plasma lipoprotein particle levels GO:0097006 23 0.972
Human
cholesterol metabolic process GO:0008203 56 0.963
organic anion transport GO:0015711 137 0.960
negative regulation of sterol transport GO:0032372 4 0.936
phospholipid efflux GO:0033700 3 0.934
organic hydroxy compound transport GO:0015850 93 0.934
intracellular sterol transport GO:0032366 3 0.922
Human
negative regulation of cholesterol transport GO:0032375 4 0.907
intracellular lipid transport GO:0032365 3 0.902
Human
positive regulation of lipid transport GO:0032370 22 0.898
regulation of lipid transport GO:0032368 36 0.896
cholesterol esterification GO:0034435 3 0.882
negative regulation of lipid transport GO:0032369 8 0.868
regulation of cholesterol metabolic process GO:0090181 14 0.864
positive regulation of cholesterol efflux GO:0010875 9 0.858
regulation of cholesterol biosynthetic process GO:0045540 8 0.857
lipid localization GO:0010876 126 0.846
high density lipoprotein particle remodeling GO:0034375 4 0.843
lipid transport GO:0006869 98 0.839
anion transport GO:0006820 177 0.834
plasma lipoprotein particle clearance GO:0034381 13 0.825
amine metabolic process GO:0009308 45 0.816
positive regulation of lipid biosynthetic process GO:0046889 18 0.813
sterol esterification GO:0034434 3 0.806
steroid metabolic process GO:0008202 119 0.803
regulation of cholesterol efflux GO:0010874 13 0.713
alcohol metabolic process GO:0006066 116 0.696
macromolecular complex remodeling GO:0034367 6 0.690
positive regulation of lipid metabolic process GO:0045834 40 0.682
cholesterol biosynthetic process GO:0006695 15 0.638
lipid biosynthetic process GO:0008610 179 0.637
steroid esterification GO:0034433 3 0.636
negative regulation of immune system process GO:0002683 209 0.607
regulation of lipid metabolic process GO:0019216 118 0.600
regulation of defense response GO:0031347 233 0.593
triglyceride metabolic process GO:0006641 51 0.591
organic hydroxy compound metabolic process GO:1901615 203 0.564
regulation of beta amyloid clearance GO:1900221 1 0.562
Mouse
cytokine production GO:0001816 319 0.561
Human
regulation of cellular catabolic process GO:0031329 242 0.551
glycerolipid metabolic process GO:0046486 122 0.530
regulation of response to wounding GO:1903034 189 0.526
innate immune response GO:0045087 157 0.521
anion homeostasis GO:0055081 16 0.511
Human
adaptive immune response GO:0002250 155 0.494
glucocorticoid metabolic process GO:0008211 9 0.483
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.479
intestinal cholesterol absorption GO:0030299 5 0.465
regulation of cellular ketone metabolic process GO:0010565 66 0.463
glycerophospholipid metabolic process GO:0006650 71 0.460
low density lipoprotein particle remodeling GO:0034374 2 0.458
sterol biosynthetic process GO:0016126 17 0.450
response to low density lipoprotein particle GO:0055098 2 0.443
Human
activation of immune response GO:0002253 138 0.441
defense response to other organism GO:0098542 197 0.441
response to lipopolysaccharide GO:0032496 128 0.441
positive regulation of presynaptic membrane organization GO:1901631 1 0.439
phospholipid homeostasis GO:0055091 6 0.437
Human
regulation of adaptive immune response GO:0002819 90 0.419
negative regulation of cell proliferation GO:0008285 296 0.385
cellular amino acid metabolic process GO:0006520 103 0.368
phospholipid metabolic process GO:0006644 87 0.367
blood vessel morphogenesis GO:0048514 285 0.366
cellular lipid metabolic process GO:0044255 323 0.366
neutral lipid metabolic process GO:0006638 57 0.363
cellular response to molecule of bacterial origin GO:0071219 83 0.357
protein lipid complex remodeling GO:0034368 6 0.356
negative regulation of cell activation GO:0050866 111 0.348
regulation of inflammatory response GO:0050727 147 0.347
lipid modification GO:0030258 65 0.345
alcohol catabolic process GO:0046164 16 0.332
epithelial cell proliferation GO:0050673 174 0.330
mapk cascade GO:0000165 281 0.320
Mouse
inflammatory response GO:0006954 244 0.316
high density lipoprotein particle assembly GO:0034380 3 0.316
Human
regulation of protein kinase activity GO:0045859 232 0.313
carbohydrate metabolic process GO:0005975 230 0.310
peptidyl tyrosine phosphorylation GO:0018108 143 0.307
lipid catabolic process GO:0016042 69 0.304
cation homeostasis GO:0055080 212 0.302
production of molecular mediator of immune response GO:0002440 103 0.301
formation of radial glial scaffolds GO:0021943 4 0.297
carbohydrate derivative biosynthetic process GO:1901137 183 0.287
Human Mouse
regulation of phospholipid efflux GO:1902994 2 0.284
Mouse
macromolecule catabolic process GO:0009057 281 0.281
cellular ketone metabolic process GO:0042180 84 0.279
protein catabolic process GO:0030163 221 0.278
regulation of lymphocyte activation GO:0051249 240 0.272
negative regulation of lipid storage GO:0010888 6 0.269
cytokine mediated signaling pathway GO:0019221 115 0.267
t cell activation GO:0042110 289 0.267
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.265
regulation of kinase activity GO:0043549 249 0.264
positive regulation of steroid metabolic process GO:0045940 5 0.258
positive regulation of innate immune response GO:0045089 80 0.255
cellular amine metabolic process GO:0044106 44 0.255
regulation of cellular amino acid metabolic process GO:0006521 5 0.252
regulation of transferase activity GO:0051338 263 0.247
steroid biosynthetic process GO:0006694 47 0.246
acylglycerol metabolic process GO:0006639 55 0.244
regulation of leukocyte mediated immunity GO:0002703 104 0.237
purine nucleotide metabolic process GO:0006163 302 0.237
Human Mouse
regulation of intestinal cholesterol absorption GO:0030300 4 0.234
regulation of t cell activation GO:0050863 170 0.233
small molecule biosynthetic process GO:0044283 132 0.232
sterol transmembrane transport GO:0035382 2 0.229
nucleoside phosphate metabolic process GO:0006753 338 0.229
Human Mouse
regulation of phospholipase a2 activity GO:0032429 3 0.225
positive regulation of transferase activity GO:0051347 167 0.225
regulation of cellular response to stress GO:0080135 159 0.223
acylglycerol homeostasis GO:0055090 16 0.223
protein modification by small protein conjugation or removal GO:0070647 207 0.221
regulation of cell activation GO:0050865 289 0.215
urogenital system development GO:0001655 261 0.214
cell substrate adhesion GO:0031589 130 0.212
negative regulation of cellular amide metabolic process GO:0034249 4 0.212
Mouse
response to organic cyclic compound GO:0014070 198 0.211
negative regulation of defense response GO:0031348 77 0.211
cellular biogenic amine metabolic process GO:0006576 28 0.210
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.209
cellular macromolecule catabolic process GO:0044265 206 0.208
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.207
regulation of cytokine production GO:0001817 266 0.206
nucleotide metabolic process GO:0009117 332 0.205
Human Mouse
intestinal absorption GO:0050892 13 0.204
positive regulation of lymphocyte activation GO:0051251 140 0.201
low density lipoprotein particle clearance GO:0034383 8 0.199
positive regulation of protein phosphorylation GO:0001934 242 0.199
cell activation involved in immune response GO:0002263 126 0.193
protein processing GO:0016485 163 0.192
regulation of lipid storage GO:0010883 20 0.191
protein glycosylation GO:0006486 55 0.190
glycerolipid biosynthetic process GO:0045017 50 0.187
triglyceride biosynthetic process GO:0019432 17 0.186
alcohol biosynthetic process GO:0046165 43 0.184
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.184
lymphocyte differentiation GO:0030098 242 0.183
g protein coupled receptor signaling pathway GO:0007186 243 0.183
Human
spermatid differentiation GO:0048515 115 0.182
spermatid development GO:0007286 108 0.179
morphogenesis of a branching epithelium GO:0061138 193 0.179
angiogenesis GO:0001525 201 0.176
lipoprotein biosynthetic process GO:0042158 33 0.174
ribonucleotide metabolic process GO:0009259 291 0.174
Human Mouse
regulation of phospholipid transport GO:2001138 4 0.173
Mouse
protein modification by small protein conjugation GO:0032446 187 0.173
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.170
small molecule catabolic process GO:0044282 71 0.170
positive regulation of dendrite development GO:1900006 21 0.169
regulation of body fluid levels GO:0050878 162 0.168
Mouse
cellular protein catabolic process GO:0044257 155 0.168
regulation of proteolysis GO:0030162 164 0.165
cdc42 protein signal transduction GO:0032488 0 0.164
Human
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.164
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.163
positive regulation of cytokine production GO:0001819 174 0.162
peptidyl amino acid modification GO:0018193 336 0.162
cellularization GO:0007349 1 0.162
extrinsic apoptotic signaling pathway GO:0097191 126 0.159
glycosylation GO:0070085 62 0.158
glial cell differentiation GO:0010001 131 0.158
posttranscriptional regulation of gene expression GO:0010608 155 0.157
toxin transport GO:1901998 38 0.157
maintenance of location GO:0051235 89 0.156
response to nutrient levels GO:0031667 109 0.156
leukocyte activation involved in immune response GO:0002366 126 0.156
regulation of reactive oxygen species metabolic process GO:2000377 40 0.155
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.155
nucleobase containing small molecule metabolic process GO:0055086 352 0.155
Human Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.155
immune effector process GO:0002252 321 0.154
regulation of cellular protein catabolic process GO:1903362 61 0.153
regulation of secretion by cell GO:1903530 249 0.152
regulation of mapk cascade GO:0043408 248 0.152
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.150
positive regulation of nervous system development GO:0051962 221 0.150
negative regulation of inflammatory response GO:0050728 61 0.150
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.148
macromolecule glycosylation GO:0043413 55 0.148
negative regulation of protein metabolic process GO:0051248 282 0.146
Mouse
cellular chemical homeostasis GO:0055082 215 0.146
immune response activating signal transduction GO:0002757 116 0.146
regulation of cell migration GO:0030334 219 0.145
cholesterol catabolic process GO:0006707 5 0.145
ion transmembrane transport GO:0034220 361 0.145
protein ubiquitination GO:0016567 171 0.142
chemotaxis GO:0006935 247 0.141
connective tissue development GO:0061448 179 0.140
defense response to bacterium GO:0042742 119 0.140
male gamete generation GO:0048232 285 0.138
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.137
gland development GO:0048732 330 0.136
positive regulation of defense response GO:0031349 124 0.135
neuron death GO:0070997 154 0.135
transmembrane transport GO:0055085 412 0.133
regulation of cellular amine metabolic process GO:0033238 20 0.133
regulation of cholesterol esterification GO:0010872 2 0.133
negative regulation of cellular component organization GO:0051129 194 0.132
regulation of digestive system process GO:0044058 13 0.132
positive regulation of cellular protein catabolic process GO:1903364 34 0.132
peptidyl tyrosine modification GO:0018212 145 0.131
skin development GO:0043588 220 0.130
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.129
leukocyte migration GO:0050900 124 0.129
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.129
negative regulation of epithelial cell proliferation GO:0050680 64 0.129
ribose phosphate metabolic process GO:0019693 291 0.128
Human Mouse
lipoprotein metabolic process GO:0042157 43 0.128
negative regulation of cellular protein metabolic process GO:0032269 247 0.128
immune response regulating signaling pathway GO:0002764 125 0.128
kidney development GO:0001822 213 0.128
lipid storage GO:0019915 36 0.127
ribonucleoside triphosphate catabolic process GO:0009203 199 0.126
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.126
regulation of neuron differentiation GO:0045664 281 0.125
cellular response to lipid GO:0071396 145 0.124
stem cell maintenance GO:0019827 130 0.124
positive regulation of programmed cell death GO:0043068 218 0.124
modification dependent macromolecule catabolic process GO:0043632 133 0.123
membrane organization GO:0061024 245 0.121
positive regulation of steroid biosynthetic process GO:0010893 4 0.120
cytokine production involved in immune response GO:0002367 34 0.120
regulation of removal of superoxide radicals GO:2000121 4 0.119
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.119
regulation of map kinase activity GO:0043405 120 0.118
monocarboxylic acid metabolic process GO:0032787 191 0.118
organic cyclic compound catabolic process GO:1901361 295 0.117
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.116
hindbrain development GO:0030902 128 0.116
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.115
response to oxidative stress GO:0006979 123 0.114
neutral lipid biosynthetic process GO:0046460 18 0.114
cellular response to hormone stimulus GO:0032870 150 0.114
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.113
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.112
Mouse
positive regulation of cell activation GO:0050867 158 0.112
positive regulation of apoptotic process GO:0043065 217 0.112
modification dependent protein catabolic process GO:0019941 133 0.111
apoptotic signaling pathway GO:0097190 306 0.111
regulation of endocytosis GO:0030100 69 0.110
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.108
positive regulation of protein kinase b signaling GO:0051897 32 0.108
negative regulation of apoptotic signaling pathway GO:2001234 104 0.107
nucleoside monophosphate metabolic process GO:0009123 85 0.107
Mouse
sterol catabolic process GO:0016127 5 0.107
negative regulation of response to wounding GO:1903035 77 0.106
beta amyloid formation GO:0034205 9 0.106
Mouse
positive regulation of mapk cascade GO:0043410 170 0.105
Mouse
coagulation GO:0050817 78 0.104
plasma lipoprotein particle assembly GO:0034377 6 0.104
Human
b cell activation GO:0042113 161 0.104
calcium ion homeostasis GO:0055074 127 0.104
reactive oxygen species biosynthetic process GO:1903409 8 0.104
erythrocyte differentiation GO:0030218 88 0.103
negative regulation of cytokine production GO:0001818 84 0.102
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.101
organic hydroxy compound catabolic process GO:1901616 25 0.101
positive regulation of ion transport GO:0043270 65 0.101
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.101
positive regulation of lipid storage GO:0010884 10 0.100
regulation of lipid biosynthetic process GO:0046890 54 0.100
muscle tissue development GO:0060537 308 0.100
axonogenesis GO:0007409 274 0.100
glycoprotein biosynthetic process GO:0009101 89 0.099
Mouse
neuron apoptotic process GO:0051402 142 0.099
appendage development GO:0048736 166 0.099
regulation of hormone levels GO:0010817 211 0.098
cellular ion homeostasis GO:0006873 165 0.098
protein localization to membrane GO:0072657 108 0.098
regulation of steroid metabolic process GO:0019218 39 0.097
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 8 0.097
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.096
lipid digestion GO:0044241 7 0.096
positive regulation of cell development GO:0010720 237 0.096
cellular response to oxidative stress GO:0034599 76 0.096
ribonucleotide catabolic process GO:0009261 208 0.095
Mouse
female sex differentiation GO:0046660 84 0.095
regulation of rho protein signal transduction GO:0035023 71 0.094
Human
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.094
lipoprotein catabolic process GO:0042159 7 0.094
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.094
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.093
phagocytosis GO:0006909 66 0.093
cellular divalent inorganic cation homeostasis GO:0072503 127 0.091
spermatogenesis GO:0007283 284 0.091
positive regulation of cellular amine metabolic process GO:0033240 5 0.091
peptide metabolic process GO:0006518 46 0.091
Mouse
forebrain development GO:0030900 302 0.089
b cell proliferation GO:0042100 53 0.089
negative regulation of endothelial cell proliferation GO:0001937 8 0.088
regulation of epithelial cell proliferation GO:0050678 141 0.088
respiratory tube development GO:0030323 167 0.087
Mouse
digestive tract development GO:0048565 190 0.087
tissue remodeling GO:0048771 102 0.086
positive regulation of protein modification process GO:0031401 299 0.086
positive regulation of t cell activation GO:0050870 101 0.086
cholesterol import GO:0070508 2 0.085
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport GO:0090118 1 0.084
innate immune response activating signal transduction GO:0002758 50 0.084
response to molecule of bacterial origin GO:0002237 143 0.084
lymphocyte mediated immunity GO:0002449 139 0.084
dendritic spine maintenance GO:0097062 4 0.084
multicellular organismal signaling GO:0035637 91 0.084
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.083
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.083
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.083
negative regulation of protein phosphorylation GO:0001933 126 0.083
nuclear transport GO:0051169 139 0.082
organic acid transport GO:0015849 101 0.082
regulation of innate immune response GO:0045088 91 0.081
response to steroid hormone GO:0048545 56 0.081
wnt signaling pathway GO:0016055 188 0.081
regulation of multi organism process GO:0043900 111 0.080
regulation of fat cell differentiation GO:0045598 81 0.080
positive regulation of glial cell proliferation GO:0060252 4 0.080
response to peptide hormone GO:0043434 127 0.080
amyloid precursor protein catabolic process GO:0042987 10 0.080
Mouse
very low density lipoprotein particle remodeling GO:0034372 1 0.080
defense response to gram positive bacterium GO:0050830 50 0.079
stress activated protein kinase signaling cascade GO:0031098 81 0.078
glucose metabolic process GO:0006006 92 0.078
dendritic spine development GO:0060996 30 0.078
organonitrogen compound biosynthetic process GO:1901566 192 0.078
Human
negative regulation of phosphorylation GO:0042326 166 0.078
ribonucleoside metabolic process GO:0009119 245 0.077
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.077
regulation of neuron apoptotic process GO:0043523 122 0.077
negative regulation of neuron death GO:1901215 98 0.077
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.076
regulation of protein processing GO:0070613 96 0.076
positive regulation of protein kinase activity GO:0045860 144 0.076
positive regulation of kinase activity GO:0033674 155 0.076
activation of innate immune response GO:0002218 56 0.075
extracellular structure organization GO:0043062 148 0.075
regulation of b cell activation GO:0050864 81 0.075
regulation of protein serine threonine kinase activity GO:0071900 157 0.075
autophagy GO:0006914 45 0.075
cellular homeostasis GO:0019725 240 0.075
stem cell proliferation GO:0072089 117 0.075
positive regulation of amyloid precursor protein catabolic process GO:1902993 4 0.074
regulation of interleukin 6 production GO:0032675 55 0.074
positive regulation of secretion by cell GO:1903532 114 0.073
t cell proliferation GO:0042098 120 0.073
regulation of non canonical wnt signaling pathway GO:2000050 12 0.073
positive regulation of beta amyloid formation GO:1902004 4 0.073
regulation of triglyceride biosynthetic process GO:0010866 10 0.072
leukocyte proliferation GO:0070661 172 0.072
somatic cell dna recombination GO:0016444 51 0.072
regulation of hydrolase activity GO:0051336 246 0.072
heterocycle catabolic process GO:0046700 280 0.071
Mouse
negative regulation of cholesterol efflux GO:0090370 4 0.071
divalent inorganic cation homeostasis GO:0072507 138 0.071
positive regulation of neuron differentiation GO:0045666 141 0.071
regulation of nucleotide metabolic process GO:0006140 169 0.071
Human
nucleoside phosphate catabolic process GO:1901292 222 0.070
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.070
cell adhesion GO:0007155 329 0.070
glycerophospholipid biosynthetic process GO:0046474 32 0.069
regulation of lymphocyte mediated immunity GO:0002706 84 0.069
sperm individualization GO:0007291 1 0.069
regulation of leukocyte proliferation GO:0070663 121 0.069
blood coagulation GO:0007596 76 0.069
excretion GO:0007588 22 0.068
placenta development GO:0001890 140 0.068
multicellular organism growth GO:0035264 161 0.068
renal system development GO:0072001 225 0.068
endocytosis GO:0006897 168 0.068
lymphocyte activation involved in immune response GO:0002285 93 0.068
tissue homeostasis GO:0001894 115 0.068
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.067
negative regulation of alcohol biosynthetic process GO:1902931 4 0.067
cell proliferation in hindbrain GO:0021534 10 0.067
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.067
regulation of ras protein signal transduction GO:0046578 114 0.066
Human
regulation of blood coagulation GO:0030193 28 0.065
sphingolipid metabolic process GO:0006665 45 0.065
regulation of neurofibrillary tangle assembly GO:1902996 1 0.065
regulation of anatomical structure size GO:0090066 178 0.065
small gtpase mediated signal transduction GO:0007264 97 0.065
Human
defense response to gram negative bacterium GO:0050829 28 0.064
liver development GO:0001889 66 0.064
aromatic compound catabolic process GO:0019439 286 0.064
Mouse
activation of mapkk activity GO:0000186 15 0.064
organophosphate catabolic process GO:0046434 232 0.064
Mouse
regulation of angiogenesis GO:0045765 81 0.064
glycerolipid catabolic process GO:0046503 16 0.063
antigen receptor mediated signaling pathway GO:0050851 64 0.063
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.063
positive regulation of hydrolase activity GO:0051345 148 0.063
negative regulation of protein maturation GO:1903318 79 0.063
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.063
organonitrogen compound catabolic process GO:1901565 264 0.063
Mouse
digestive tract morphogenesis GO:0048546 147 0.063
digestion GO:0007586 40 0.062
regulation of tube size GO:0035150 57 0.062
regulation of protein catabolic process GO:0042176 108 0.061
triglyceride rich lipoprotein particle remodeling GO:0034370 2 0.061
neural precursor cell proliferation GO:0061351 121 0.061
negative regulation of nervous system development GO:0051961 156 0.061
somatic stem cell maintenance GO:0035019 47 0.060
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.060
negative regulation of neuron apoptotic process GO:0043524 92 0.060
immunoglobulin mediated immune response GO:0016064 69 0.060
positive regulation of inflammatory response GO:0050729 47 0.059
glycosyl compound metabolic process GO:1901657 246 0.059
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.058
epidermis development GO:0008544 187 0.058
Mouse
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.058
ribonucleoside catabolic process GO:0042454 206 0.058
Mouse
protein kinase b signaling GO:0043491 74 0.058
glycoprotein metabolic process GO:0009100 116 0.058
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.058
cellular response to organic cyclic compound GO:0071407 87 0.058
cellular response to external stimulus GO:0071496 88 0.057
positive regulation of adaptive immune response GO:0002821 61 0.057
innate immune response in mucosa GO:0002227 3 0.057
regulation of protein kinase b signaling GO:0051896 56 0.057
regulation of presynaptic membrane organization GO:1901629 3 0.057
cerebellum development GO:0021549 77 0.056
regulation of production of molecular mediator of immune response GO:0002700 65 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.056
negative regulation of hydrolase activity GO:0051346 71 0.056
organophosphate biosynthetic process GO:0090407 122 0.056
Human
cell maturation GO:0048469 127 0.056
heart morphogenesis GO:0003007 178 0.055
low density lipoprotein receptor particle metabolic process GO:0032799 4 0.055
granulocyte chemotaxis GO:0071621 39 0.055
negative regulation of lymphocyte activation GO:0051250 91 0.055
gliogenesis GO:0042063 141 0.054
regulation of phospholipid catabolic process GO:0060696 2 0.054
cellular metal ion homeostasis GO:0006875 151 0.054
axis elongation involved in somitogenesis GO:0090245 4 0.054
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.054
lung development GO:0030324 164 0.053
Mouse
muscle cell differentiation GO:0042692 261 0.053
interleukin 1 beta production GO:0032611 30 0.053
Human
i kappab kinase nf kappab signaling GO:0007249 85 0.053
sterol import GO:0035376 2 0.053
stem cell development GO:0048864 219 0.053
engulfment of apoptotic cell GO:0043652 3 0.053
Mouse
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.052
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.052
acylglycerol biosynthetic process GO:0046463 18 0.052
cellular response to steroid hormone stimulus GO:0071383 33 0.052
dendrite development GO:0016358 115 0.052
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.052
Human
t cell activation involved in immune response GO:0002286 43 0.051
regulation of lymphocyte proliferation GO:0050670 117 0.051
granulocyte migration GO:0097530 43 0.051
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.051
pattern recognition receptor signaling pathway GO:0002221 47 0.050
regulation of platelet derived growth factor receptor beta signaling pathway GO:2000586 2 0.050
skeletal muscle organ development GO:0060538 163 0.050
cerebral cortex development GO:0021987 86 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
Mouse
regulation of amyloid precursor protein catabolic process GO:1902991 8 0.050
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.050

Abca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.686
Human
inherited metabolic disorder DOID:655 0 0.686
Human
retinal disease DOID:5679 0 0.546
sensory system disease DOID:0050155 0 0.546
disease of anatomical entity DOID:7 0 0.546
eye and adnexa disease DOID:1492 0 0.546
nervous system disease DOID:863 0 0.546
eye disease DOID:5614 0 0.546
retinal degeneration DOID:8466 0 0.291
immune system disease DOID:2914 0 0.226
lymphatic system disease DOID:75 0 0.213
lipid storage disease DOID:9455 0 0.170
lysosomal storage disease DOID:3211 0 0.170
sphingolipidosis DOID:1927 0 0.091
hemolytic anemia DOID:583 0 0.056
hemolytic uremic syndrome DOID:12554 0 0.056
normocytic anemia DOID:720 0 0.056
anemia DOID:2355 0 0.056
hematopoietic system disease DOID:74 0 0.056