Mus musculus

87 known processes

Abcg2

ATP-binding cassette, sub-family G (WHITE), member 2

(Aliases: Bcrp1,ABC15,MXR,AI428558,BCRP,ABCP,MXR1)

Abcg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 338 0.092
nucleoside metabolic process GO:0009116 246 0.091
purine ribonucleoside catabolic process GO:0046130 205 0.088
nucleobase containing small molecule metabolic process GO:0055086 352 0.077
organophosphate catabolic process GO:0046434 232 0.075
purine nucleoside metabolic process GO:0042278 241 0.073
purine ribonucleotide metabolic process GO:0009150 290 0.071
oxidation reduction process GO:0055114 342 0.071
cellular amino acid metabolic process GO:0006520 103 0.068
heterocycle catabolic process GO:0046700 280 0.068
purine nucleotide metabolic process GO:0006163 302 0.067
amine metabolic process GO:0009308 45 0.066
regulation of hydrolase activity GO:0051336 246 0.066
cellular amine metabolic process GO:0044106 44 0.065
ribose phosphate metabolic process GO:0019693 291 0.065
nucleotide metabolic process GO:0009117 332 0.065
organonitrogen compound catabolic process GO:1901565 264 0.064
protein catabolic process GO:0030163 221 0.063
carbohydrate derivative catabolic process GO:1901136 231 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.063
cellular lipid metabolic process GO:0044255 323 0.062
aromatic compound catabolic process GO:0019439 286 0.061
cellular nitrogen compound catabolic process GO:0044270 280 0.061
glycosyl compound catabolic process GO:1901658 206 0.061
nucleoside triphosphate metabolic process GO:0009141 230 0.060
organic cyclic compound catabolic process GO:1901361 295 0.059
rab protein signal transduction GO:0032482 1 0.058
purine nucleoside catabolic process GO:0006152 205 0.056
negative regulation of molecular function GO:0044092 258 0.052
transmembrane transport GO:0055085 412 0.052
nucleoside catabolic process GO:0009164 206 0.052
ribonucleotide metabolic process GO:0009259 291 0.051
purine containing compound catabolic process GO:0072523 213 0.051
small gtpase mediated signal transduction GO:0007264 97 0.050
cell adhesion GO:0007155 329 0.048
ras protein signal transduction GO:0007265 77 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
ribonucleoside catabolic process GO:0042454 206 0.046
glycosyl compound metabolic process GO:1901657 246 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
ribonucleotide catabolic process GO:0009261 208 0.043
ribonucleoside metabolic process GO:0009119 245 0.041
apoptotic signaling pathway GO:0097190 306 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
nucleoside phosphate catabolic process GO:1901292 222 0.040
ion transmembrane transport GO:0034220 361 0.040
nucleoside triphosphate catabolic process GO:0009143 205 0.040
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
nitrogen compound transport GO:0071705 271 0.038
positive regulation of cell death GO:0010942 224 0.038
myeloid cell differentiation GO:0030099 233 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
intracellular protein transport GO:0006886 204 0.036
regulation of purine nucleotide catabolic process GO:0033121 122 0.036
protein localization to organelle GO:0033365 185 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
endomembrane system organization GO:0010256 147 0.036
peptidyl amino acid modification GO:0018193 336 0.035
negative regulation of cell proliferation GO:0008285 296 0.034
membrane organization GO:0061024 245 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
defense response to other organism GO:0098542 197 0.032
purine nucleotide catabolic process GO:0006195 211 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
positive regulation of apoptotic process GO:0043065 217 0.031
regulation of cell activation GO:0050865 289 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
anion transport GO:0006820 177 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
macromolecule catabolic process GO:0009057 281 0.031
endocytosis GO:0006897 168 0.031
cellular homeostasis GO:0019725 240 0.030
regulation of kinase activity GO:0043549 249 0.030
negative regulation of immune system process GO:0002683 209 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
nucleotide catabolic process GO:0009166 217 0.029
cofactor metabolic process GO:0051186 80 0.029
cellular ketone metabolic process GO:0042180 84 0.029
protein processing GO:0016485 163 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.028
regulation of nucleotide catabolic process GO:0030811 122 0.028
homeostasis of number of cells GO:0048872 210 0.028
regulation of transferase activity GO:0051338 263 0.027
guanosine containing compound metabolic process GO:1901068 144 0.027
regulation of protein localization GO:0032880 231 0.027
response to growth factor GO:0070848 198 0.027
protein maturation GO:0051604 176 0.027
positive regulation of protein modification process GO:0031401 299 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
response to organonitrogen compound GO:0010243 246 0.027
Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
regulation of mapk cascade GO:0043408 248 0.026
response to inorganic substance GO:0010035 96 0.026
Rat
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
immune effector process GO:0002252 321 0.026
glycerolipid metabolic process GO:0046486 122 0.025
inflammatory response GO:0006954 244 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
myeloid cell homeostasis GO:0002262 114 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
purine containing compound metabolic process GO:0072521 311 0.025
spermatogenesis GO:0007283 284 0.025
cation transport GO:0006812 399 0.025
response to lipopolysaccharide GO:0032496 128 0.025
regulation of protein kinase activity GO:0045859 232 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of cell motility GO:2000145 236 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
urogenital system development GO:0001655 261 0.024
positive regulation of programmed cell death GO:0043068 218 0.023
cytokine production GO:0001816 319 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
regulation of organelle organization GO:0033043 289 0.023
regulation of ras gtpase activity GO:0032318 88 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
positive regulation of cell development GO:0010720 237 0.023
male gamete generation GO:0048232 285 0.022
retrograde transport endosome to golgi GO:0042147 2 0.022
cell type specific apoptotic process GO:0097285 268 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
Rat
negative regulation of protein metabolic process GO:0051248 282 0.021
innate immune response GO:0045087 157 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
response to oxidative stress GO:0006979 123 0.021
leukocyte differentiation GO:0002521 342 0.021
divalent metal ion transport GO:0070838 172 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
cytoplasmic transport GO:0016482 234 0.021
multicellular organismal homeostasis GO:0048871 164 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
response to organic cyclic compound GO:0014070 198 0.020
Rat
carbohydrate metabolic process GO:0005975 230 0.020
mapk cascade GO:0000165 281 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
cation homeostasis GO:0055080 212 0.020
organic acid transport GO:0015849 101 0.020
peptidyl tyrosine modification GO:0018212 145 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
regulation of body fluid levels GO:0050878 162 0.020
anion transmembrane transport GO:0098656 71 0.019
cellular chemical homeostasis GO:0055082 215 0.019
divalent inorganic cation transport GO:0072511 178 0.019
gonad development GO:0008406 141 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
synaptic transmission GO:0007268 329 0.019
regulation of ion transport GO:0043269 215 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
regulation of membrane potential GO:0042391 192 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
sulfur compound biosynthetic process GO:0044272 37 0.018
regulation of cellular response to stress GO:0080135 159 0.018
glycoprotein metabolic process GO:0009100 116 0.018
alcohol metabolic process GO:0006066 116 0.018
sequestering of metal ion GO:0051238 19 0.018
gland development GO:0048732 330 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
response to acid chemical GO:0001101 111 0.018
Rat
regulation of response to wounding GO:1903034 189 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
development of primary sexual characteristics GO:0045137 143 0.018
dna metabolic process GO:0006259 303 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
protein localization to nucleus GO:0034504 121 0.018
blood circulation GO:0008015 195 0.018
organic acid biosynthetic process GO:0016053 86 0.018
phospholipid metabolic process GO:0006644 87 0.018
circulatory system process GO:0003013 197 0.018
gtp metabolic process GO:0046039 144 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of cell cycle GO:0051726 281 0.017
negative regulation of protein modification process GO:0031400 163 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of peptidase activity GO:0052547 96 0.017
gtp catabolic process GO:0006184 143 0.017
positive regulation of kinase activity GO:0033674 155 0.017
sensory perception GO:0007600 245 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of proteolysis GO:0030162 164 0.017
protein import GO:0017038 101 0.017
lipid biosynthetic process GO:0008610 179 0.017
regulation of cell migration GO:0030334 219 0.016
organic anion transport GO:0015711 137 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
sequestering of calcium ion GO:0051208 18 0.016
glucose homeostasis GO:0042593 128 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
nuclear transport GO:0051169 139 0.016
regulation of defense response GO:0031347 233 0.016
regulation of t cell activation GO:0050863 170 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
anatomical structure homeostasis GO:0060249 145 0.016
regulation of secretion by cell GO:1903530 249 0.016
metal ion homeostasis GO:0055065 189 0.016
establishment of vesicle localization GO:0051650 81 0.016
cellular response to lipid GO:0071396 145 0.016
Rat
wound healing GO:0042060 157 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
chemotaxis GO:0006935 247 0.016
skeletal system development GO:0001501 356 0.016
membrane lipid biosynthetic process GO:0046467 32 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
digestive system development GO:0055123 200 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
steroid metabolic process GO:0008202 119 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
cellular protein catabolic process GO:0044257 155 0.016
tissue homeostasis GO:0001894 115 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
fatty acid metabolic process GO:0006631 121 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
regulation of transmembrane transport GO:0034762 128 0.015
cellular ion homeostasis GO:0006873 165 0.015
sensory organ morphogenesis GO:0090596 242 0.015
cellularization GO:0007349 1 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
lymphocyte differentiation GO:0030098 242 0.015
renal system development GO:0072001 225 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
cation transmembrane transport GO:0098655 266 0.015
single organism cell adhesion GO:0098602 156 0.015
positive regulation of transferase activity GO:0051347 167 0.015
organelle fission GO:0048285 170 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
atp metabolic process GO:0046034 75 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
spermatid development GO:0007286 108 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
stem cell differentiation GO:0048863 268 0.014
negative regulation of transferase activity GO:0051348 85 0.014
microtubule based process GO:0007017 236 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of cytokine production GO:0001817 266 0.014
blood coagulation GO:0007596 76 0.014
regulation of neuron differentiation GO:0045664 281 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
interleukin 8 production GO:0032637 4 0.014
neuronal action potential GO:0019228 54 0.014
transmission of nerve impulse GO:0019226 76 0.014
regulation of protein maturation GO:1903317 96 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
single organism nuclear import GO:1902593 95 0.014
negative regulation of kinase activity GO:0033673 81 0.014
regulation of hormone levels GO:0010817 211 0.014
defense response to bacterium GO:0042742 119 0.014
spermatid differentiation GO:0048515 115 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of map kinase activity GO:0043405 120 0.014
regulation of homeostatic process GO:0032844 182 0.014
fertilization GO:0009566 127 0.014
response to extracellular stimulus GO:0009991 127 0.014
Rat
regulation of clathrin mediated endocytosis GO:2000369 4 0.014
b cell activation GO:0042113 161 0.014
small molecule biosynthetic process GO:0044283 132 0.014
cellular response to oxidative stress GO:0034599 76 0.014
negative regulation of complement activation GO:0045916 3 0.014
regulation of cellular response to growth factor stimulus GO:0090287 82 0.014
lipid transport GO:0006869 98 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.013
heart morphogenesis GO:0003007 178 0.013
muscle cell differentiation GO:0042692 261 0.013
oocyte construction GO:0007308 2 0.013
regulation of multi organism process GO:0043900 111 0.013
negative regulation of cell activation GO:0050866 111 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
kidney development GO:0001822 213 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
response to radiation GO:0009314 165 0.013
regulation of neurotransmitter levels GO:0001505 87 0.013
protein import into nucleus GO:0006606 95 0.013
cholesterol metabolic process GO:0008203 56 0.013
regulation of inflammatory response GO:0050727 147 0.013
response to reactive oxygen species GO:0000302 56 0.013
amide transport GO:0042886 138 0.013
organelle localization GO:0051640 179 0.012
multi multicellular organism process GO:0044706 109 0.012
Rat
carbohydrate homeostasis GO:0033500 128 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
coagulation GO:0050817 78 0.012
response to light stimulus GO:0009416 135 0.012
regulation of endocytosis GO:0030100 69 0.012
muscle system process GO:0003012 141 0.012
mitotic cell cycle GO:0000278 195 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
respiratory system development GO:0060541 190 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
t cell activation GO:0042110 289 0.012
extracellular matrix organization GO:0030198 147 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
regulation of secretion GO:0051046 274 0.012
organic hydroxy compound transport GO:0015850 93 0.012
negative regulation of cell cycle GO:0045786 123 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
peptide transport GO:0015833 133 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
positive regulation of cytokine production GO:0001819 174 0.012
cellular protein complex assembly GO:0043623 116 0.012
dephosphorylation GO:0016311 129 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
regulation of cell adhesion GO:0030155 154 0.012
hemostasis GO:0007599 78 0.012
ossification GO:0001503 216 0.012
sulfur compound metabolic process GO:0006790 100 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
epidermis development GO:0008544 187 0.012
vesicle localization GO:0051648 86 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
positive regulation of defense response GO:0031349 124 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
fat cell differentiation GO:0045444 160 0.012
lymphocyte proliferation GO:0046651 164 0.012
meiotic cell cycle GO:0051321 122 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
neuron death GO:0070997 154 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
calcium ion transport GO:0006816 159 0.011
action potential GO:0001508 78 0.011
developmental maturation GO:0021700 193 0.011
regulation of cell projection organization GO:0031344 206 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
nucleotide transmembrane transport GO:1901679 2 0.011
heart process GO:0003015 94 0.011
response to nutrient levels GO:0031667 109 0.011
Rat
regulation of ras protein signal transduction GO:0046578 114 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
maintenance of location GO:0051235 89 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of intracellular transport GO:0032386 159 0.011
positive regulation of rab gtpase activity GO:0032851 7 0.011
exocytosis GO:0006887 121 0.011
nuclear import GO:0051170 95 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
thrombin receptor signaling pathway GO:0070493 2 0.011
interleukin 8 secretion GO:0072606 3 0.011
protein ubiquitination GO:0016567 171 0.011
ear development GO:0043583 200 0.011
response to peptide hormone GO:0043434 127 0.011
response to steroid hormone GO:0048545 56 0.011
Rat
rho protein signal transduction GO:0007266 32 0.011
negative regulation of protein processing GO:0010955 79 0.011
oocyte axis specification GO:0007309 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
regionalization GO:0003002 337 0.011
l amino acid transport GO:0015807 32 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.010
digestive tract development GO:0048565 190 0.010
skin development GO:0043588 220 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
lipid localization GO:0010876 126 0.010
nonribosomal peptide biosynthetic process GO:0019184 5 0.010
respiratory tube development GO:0030323 167 0.010
plasma membrane organization GO:0007009 90 0.010
regulation of anatomical structure size GO:0090066 178 0.010
neuron apoptotic process GO:0051402 142 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
response to peptide GO:1901652 136 0.010
protein targeting GO:0006605 143 0.010
male sex differentiation GO:0046661 109 0.010
transition metal ion homeostasis GO:0055076 54 0.010
myosin filament assembly GO:0031034 2 0.010
germ cell development GO:0007281 185 0.010
small molecule catabolic process GO:0044282 71 0.010
striated muscle tissue development GO:0014706 293 0.010
positive regulation of secretion GO:0051047 130 0.010
negative regulation of protein maturation GO:1903318 79 0.010
response to insulin GO:0032868 100 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
response to transforming growth factor beta GO:0071559 88 0.010
wnt signaling pathway GO:0016055 188 0.010
lateral inhibition GO:0046331 1 0.010

Abcg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.041
disease of metabolism DOID:0014667 0 0.041
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
immune system disease DOID:2914 0 0.020
sensory system disease DOID:0050155 0 0.016
hematopoietic system disease DOID:74 0 0.014
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
central nervous system disease DOID:331 0 0.010