Mus musculus

93 known processes

Acadl

acyl-Coenzyme A dehydrogenase, long-chain

(Aliases: C79855,AA960361,LCAD,AU018452)

Acadl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.596
lipid oxidation GO:0034440 29 0.561
fatty acid oxidation GO:0019395 28 0.519
cellular lipid metabolic process GO:0044255 323 0.507
lipid catabolic process GO:0016042 69 0.323
small molecule catabolic process GO:0044282 71 0.318
fatty acid metabolic process GO:0006631 121 0.279
cellular lipid catabolic process GO:0044242 52 0.250
nucleobase containing small molecule metabolic process GO:0055086 352 0.186
nucleotide metabolic process GO:0009117 332 0.175
carnitine metabolic process GO:0009437 7 0.165
nucleoside phosphate metabolic process GO:0006753 338 0.159
monocarboxylic acid metabolic process GO:0032787 191 0.148
cellular ketone metabolic process GO:0042180 84 0.145
fatty acid beta oxidation GO:0006635 16 0.142
carboxylic acid catabolic process GO:0046395 51 0.134
ribonucleoside triphosphate metabolic process GO:0009199 220 0.118
lipid modification GO:0030258 65 0.112
purine ribonucleoside metabolic process GO:0046128 241 0.101
fatty acid catabolic process GO:0009062 25 0.100
purine nucleoside metabolic process GO:0042278 241 0.094
purine ribonucleotide metabolic process GO:0009150 290 0.093
monocarboxylic acid catabolic process GO:0072329 27 0.085
ribose phosphate metabolic process GO:0019693 291 0.084
ribonucleotide metabolic process GO:0009259 291 0.084
cellular nitrogen compound catabolic process GO:0044270 280 0.080
lipid biosynthetic process GO:0008610 179 0.078
transmembrane transport GO:0055085 412 0.073
organic anion transport GO:0015711 137 0.072
organic hydroxy compound metabolic process GO:1901615 203 0.069
heterocycle catabolic process GO:0046700 280 0.069
nucleoside metabolic process GO:0009116 246 0.067
medium chain fatty acid metabolic process GO:0051791 1 0.066
protein oligomerization GO:0051259 67 0.064
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.063
acylglycerol metabolic process GO:0006639 55 0.062
organic acid catabolic process GO:0016054 51 0.061
purine nucleoside triphosphate metabolic process GO:0009144 226 0.060
amino acid betaine metabolic process GO:0006577 7 0.060
organic cyclic compound catabolic process GO:1901361 295 0.057
thioester metabolic process GO:0035383 19 0.057
purine nucleotide metabolic process GO:0006163 302 0.056
amine metabolic process GO:0009308 45 0.052
cellular amine metabolic process GO:0044106 44 0.050
glycosyl compound metabolic process GO:1901657 246 0.048
glycerolipid metabolic process GO:0046486 122 0.047
mitochondrion organization GO:0007005 134 0.045
nucleoside monophosphate metabolic process GO:0009123 85 0.045
ribonucleoside metabolic process GO:0009119 245 0.045
purine ribonucleoside catabolic process GO:0046130 205 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
ion transmembrane transport GO:0034220 361 0.043
purine containing compound metabolic process GO:0072521 311 0.042
cytoplasmic transport GO:0016482 234 0.041
very long chain fatty acid catabolic process GO:0042760 2 0.040
regulation of cellular catabolic process GO:0031329 242 0.040
regulation of apoptotic signaling pathway GO:2001233 197 0.039
aromatic compound catabolic process GO:0019439 286 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
organophosphate biosynthetic process GO:0090407 122 0.038
generation of precursor metabolites and energy GO:0006091 103 0.038
glycosyl compound catabolic process GO:1901658 206 0.038
purine containing compound catabolic process GO:0072523 213 0.037
anion transport GO:0006820 177 0.037
lipid transport GO:0006869 98 0.037
response to organonitrogen compound GO:0010243 246 0.035
monocarboxylic acid transport GO:0015718 44 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.035
cellular response to hormone stimulus GO:0032870 150 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
organonitrogen compound catabolic process GO:1901565 264 0.034
glycerolipid biosynthetic process GO:0045017 50 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
cofactor metabolic process GO:0051186 80 0.033
regulation of cytokine production GO:0001817 266 0.033
apoptotic signaling pathway GO:0097190 306 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
positive regulation of protein modification process GO:0031401 299 0.032
protein processing GO:0016485 163 0.032
organophosphate catabolic process GO:0046434 232 0.032
regulation of mitochondrial fission GO:0090140 3 0.032
neutral lipid metabolic process GO:0006638 57 0.032
cytokine production GO:0001816 319 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
response to nutrient levels GO:0031667 109 0.031
regulation of membrane potential GO:0042391 192 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
membrane organization GO:0061024 245 0.030
energy derivation by oxidation of organic compounds GO:0015980 77 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
triglyceride metabolic process GO:0006641 51 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
dephosphorylation GO:0016311 129 0.030
spermatogenesis GO:0007283 284 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
atp metabolic process GO:0046034 75 0.029
response to lipopolysaccharide GO:0032496 128 0.029
male gamete generation GO:0048232 285 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
very long chain fatty acid metabolic process GO:0000038 8 0.029
coenzyme metabolic process GO:0006732 52 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
cholesterol homeostasis GO:0042632 44 0.028
regulation of organelle organization GO:0033043 289 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
purine nucleoside monophosphate metabolic process GO:0009126 81 0.028
regulation of lipid metabolic process GO:0019216 118 0.028
organic acid transport GO:0015849 101 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
anion transmembrane transport GO:0098656 71 0.027
mitochondrial transport GO:0006839 36 0.026
macromolecule catabolic process GO:0009057 281 0.026
intracellular protein transport GO:0006886 204 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.026
establishment of protein localization to organelle GO:0072594 118 0.025
immune effector process GO:0002252 321 0.025
cation transport GO:0006812 399 0.025
regulation of secretion GO:0051046 274 0.025
response to extracellular stimulus GO:0009991 127 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
response to inorganic substance GO:0010035 96 0.025
regulation of hydrolase activity GO:0051336 246 0.025
organelle localization GO:0051640 179 0.025
carbohydrate metabolic process GO:0005975 230 0.024
cell type specific apoptotic process GO:0097285 268 0.024
steroid metabolic process GO:0008202 119 0.024
gland development GO:0048732 330 0.024
protein localization to organelle GO:0033365 185 0.024
carboxylic acid transport GO:0046942 100 0.024
response to oxidative stress GO:0006979 123 0.023
response to organic cyclic compound GO:0014070 198 0.023
regulation of fatty acid oxidation GO:0046320 10 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
myeloid cell differentiation GO:0030099 233 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
nucleotide catabolic process GO:0009166 217 0.023
regulation of cellular response to stress GO:0080135 159 0.023
homeostasis of number of cells GO:0048872 210 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
protein localization to membrane GO:0072657 108 0.022
endomembrane system organization GO:0010256 147 0.022
protein maturation GO:0051604 176 0.022
lipid localization GO:0010876 126 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
guanosine containing compound metabolic process GO:1901068 144 0.022
cation homeostasis GO:0055080 212 0.022
positive regulation of cell death GO:0010942 224 0.022
protein targeting GO:0006605 143 0.021
protein localization to plasma membrane GO:0072659 57 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
regulation of kinase activity GO:0043549 249 0.021
negative regulation of immune system process GO:0002683 209 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
negative regulation of molecular function GO:0044092 258 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
forebrain development GO:0030900 302 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
leukocyte differentiation GO:0002521 342 0.020
alcohol metabolic process GO:0006066 116 0.020
response to oxygen levels GO:0070482 62 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
maintenance of location GO:0051235 89 0.020
pyruvate transport GO:0006848 2 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
sensory perception GO:0007600 245 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.019
mapk cascade GO:0000165 281 0.019
response to peptide GO:1901652 136 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
sulfur compound metabolic process GO:0006790 100 0.019
response to metal ion GO:0010038 47 0.019
cation transmembrane transport GO:0098655 266 0.019
nucleoside catabolic process GO:0009164 206 0.019
response to reactive oxygen species GO:0000302 56 0.019
protein homooligomerization GO:0051260 43 0.019
Rat
endocytosis GO:0006897 168 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.018
regulation of protein localization GO:0032880 231 0.018
response to growth factor GO:0070848 198 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
cellular response to lipid GO:0071396 145 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
small molecule biosynthetic process GO:0044283 132 0.018
hepaticobiliary system development GO:0061008 67 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
muscle tissue development GO:0060537 308 0.018
nitrogen compound transport GO:0071705 271 0.018
germ cell development GO:0007281 185 0.018
regulation of secretion by cell GO:1903530 249 0.018
phospholipid metabolic process GO:0006644 87 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
organelle fission GO:0048285 170 0.017
ras protein signal transduction GO:0007265 77 0.017
striated muscle tissue development GO:0014706 293 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
regulation of transferase activity GO:0051338 263 0.017
cell adhesion GO:0007155 329 0.017
blood vessel morphogenesis GO:0048514 285 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of lipid catabolic process GO:0050994 15 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
peptide metabolic process GO:0006518 46 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
regulation of hormone levels GO:0010817 211 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
rhythmic process GO:0048511 174 0.016
ossification GO:0001503 216 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
protein ubiquitination GO:0016567 171 0.016
cellular amide metabolic process GO:0043603 58 0.016
translation GO:0006412 93 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
response to insulin GO:0032868 100 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of homeostatic process GO:0032844 182 0.016
synaptic transmission GO:0007268 329 0.015
inflammatory response GO:0006954 244 0.015
cellular response to insulin stimulus GO:0032869 78 0.015
developmental maturation GO:0021700 193 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
sterol metabolic process GO:0016125 58 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
gtp catabolic process GO:0006184 143 0.015
fatty acid transmembrane transport GO:1902001 1 0.015
regulation of cell cycle GO:0051726 281 0.015
cellular ion homeostasis GO:0006873 165 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
response to drug GO:0042493 75 0.015
cellular homeostasis GO:0019725 240 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
renal system development GO:0072001 225 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
cellular respiration GO:0045333 38 0.015
response to peptide hormone GO:0043434 127 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
positive regulation of secretion GO:0051047 130 0.015
nuclear transport GO:0051169 139 0.015
skin development GO:0043588 220 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
defense response to other organism GO:0098542 197 0.014
positive regulation of organelle organization GO:0010638 128 0.014
acyl coa metabolic process GO:0006637 19 0.014
response to oxygen radical GO:0000305 16 0.014
regulation of defense response GO:0031347 233 0.014
microtubule based process GO:0007017 236 0.014
peptidyl amino acid modification GO:0018193 336 0.014
epidermis development GO:0008544 187 0.014
neuron death GO:0070997 154 0.014
innate immune response GO:0045087 157 0.014
cellular response to peptide GO:1901653 92 0.014
sterol homeostasis GO:0055092 45 0.014
t cell activation GO:0042110 289 0.014
liver development GO:0001889 66 0.014
organic acid biosynthetic process GO:0016053 86 0.014
spermatid differentiation GO:0048515 115 0.014
plasma membrane organization GO:0007009 90 0.014
response to radiation GO:0009314 165 0.014
metal ion homeostasis GO:0055065 189 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
action potential GO:0001508 78 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
leukocyte mediated immunity GO:0002443 174 0.013
multicellular organismal signaling GO:0035637 91 0.013
lymphocyte proliferation GO:0046651 164 0.013
long chain fatty acid metabolic process GO:0001676 26 0.013
Rat
heart morphogenesis GO:0003007 178 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
transmission of nerve impulse GO:0019226 76 0.013
glucose homeostasis GO:0042593 128 0.013
positive regulation of fatty acid oxidation GO:0046321 4 0.013
regulation of neuron differentiation GO:0045664 281 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
glucan metabolic process GO:0044042 32 0.013
dna metabolic process GO:0006259 303 0.013
regulation of response to wounding GO:1903034 189 0.013
establishment of vesicle localization GO:0051650 81 0.013
phospholipid biosynthetic process GO:0008654 36 0.012
cellular chemical homeostasis GO:0055082 215 0.012
positive regulation of cell activation GO:0050867 158 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
telencephalon development GO:0021537 186 0.012
urogenital system development GO:0001655 261 0.012
positive regulation of defense response GO:0031349 124 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
establishment of protein localization to peroxisome GO:0072663 4 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
positive regulation of transferase activity GO:0051347 167 0.012
epithelial cell proliferation GO:0050673 174 0.012
divalent metal ion transport GO:0070838 172 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
response to hypoxia GO:0001666 58 0.012
compound eye development GO:0048749 1 0.012
regulation of neuron death GO:1901214 134 0.012
long chain fatty acid import GO:0044539 2 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of kinase activity GO:0033674 155 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
regulation of protein transport GO:0051223 163 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
regulation of fatty acid beta oxidation GO:0031998 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
positive regulation of growth GO:0045927 104 0.012
response to acid chemical GO:0001101 111 0.012
tissue homeostasis GO:0001894 115 0.011
neuronal action potential GO:0019228 54 0.011
isoprenoid metabolic process GO:0006720 29 0.011
glycogen metabolic process GO:0005977 32 0.011
protein import GO:0017038 101 0.011
lymphocyte differentiation GO:0030098 242 0.011
cellular response to oxidative stress GO:0034599 76 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
positive regulation of immune effector process GO:0002699 107 0.011
circadian regulation of gene expression GO:0032922 48 0.011
fatty acid alpha oxidation GO:0001561 2 0.011
blood circulation GO:0008015 195 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of intracellular transport GO:0032386 159 0.011
circulatory system process GO:0003013 197 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
negative regulation of protein modification process GO:0031400 163 0.011
glucose metabolic process GO:0006006 92 0.011
rna processing GO:0006396 105 0.011
epithelium migration GO:0090132 63 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
development of primary sexual characteristics GO:0045137 143 0.011
neuron apoptotic process GO:0051402 142 0.011
single organism nuclear import GO:1902593 95 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of ion transport GO:0043269 215 0.011
camera type eye development GO:0043010 266 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
cellular glucan metabolic process GO:0006073 32 0.011
lipid homeostasis GO:0055088 63 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
monosaccharide metabolic process GO:0005996 106 0.011
negative regulation of neuron death GO:1901215 98 0.011
calcium ion transport GO:0006816 159 0.010
axonogenesis GO:0007409 274 0.010
negative regulation of cytokine production GO:0001818 84 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
kidney development GO:0001822 213 0.010
protein secretion GO:0009306 111 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
response to starvation GO:0042594 65 0.010
asymmetric stem cell division GO:0098722 3 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
regulation of protein kinase activity GO:0045859 232 0.010
skeletal system development GO:0001501 356 0.010
circadian rhythm GO:0007623 114 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
response to steroid hormone GO:0048545 56 0.010
respiratory system development GO:0060541 190 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
hexose metabolic process GO:0019318 98 0.010
muscle cell differentiation GO:0042692 261 0.010
acylglycerol biosynthetic process GO:0046463 18 0.010
positive regulation of cytokine production GO:0001819 174 0.010
phagocytosis GO:0006909 66 0.010
angiogenesis GO:0001525 201 0.010
cell maturation GO:0048469 127 0.010
carbohydrate homeostasis GO:0033500 128 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
cholesterol metabolic process GO:0008203 56 0.010
hormone secretion GO:0046879 128 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
nuclear import GO:0051170 95 0.010

Acadl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.165
disease of metabolism DOID:0014667 0 0.165
nervous system disease DOID:863 0 0.021
disease of anatomical entity DOID:7 0 0.021
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
amino acid metabolic disorder DOID:9252 0 0.016
organic acidemia DOID:0060159 0 0.016
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010