|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.974
|
|
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
2 |
0.855
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.845
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.818
|
|
|
|
regulation of dopamine secretion
|
GO:0014059 |
9 |
0.801
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.752
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.733
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.620
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.607
|
|
|
|
regulation of acetylcholine secretion neurotransmission
|
GO:0014056 |
2 |
0.607
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.558
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.536
|
|
|
|
regulation of catecholamine secretion
|
GO:0050433 |
12 |
0.531
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.527
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.516
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.498
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.475
|
|
|
|
catecholamine secretion
|
GO:0050432 |
15 |
0.475
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.458
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.452
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.448
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.436
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.435
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.434
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.394
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.392
|
|
|
|
dopamine secretion
|
GO:0014046 |
9 |
0.384
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.382
|
|
|
|
positive regulation of dopamine secretion
|
GO:0033603 |
2 |
0.378
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.374
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.364
|
|
|
|
circadian sleep wake cycle rem sleep
|
GO:0042747 |
1 |
0.360
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.347
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.341
|
|
|
|
positive regulation of catecholamine secretion
|
GO:0033605 |
2 |
0.340
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.330
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.330
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.329
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.325
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.299
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.295
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.275
|
|
|
|
regulation of circadian sleep wake cycle rem sleep
|
GO:0042320 |
1 |
0.271
|
|
|
|
visual perception
|
GO:0007601 |
52 |
0.269
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.263
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.262
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.261
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.249
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.241
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.240
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.235
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.229
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.228
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.227
|
|
|
|
amine transport
|
GO:0015837 |
21 |
0.226
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.224
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.224
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.215
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.215
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.214
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.211
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.211
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.208
|
Fly |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.207
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.207
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.202
|
Zebrafish |
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.200
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.198
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.198
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.198
|
|
|
|
generation of ovulation cycle rhythm
|
GO:0060112 |
1 |
0.198
|
|
|
|
synaptic transmission involved in micturition
|
GO:0060084 |
3 |
0.196
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.195
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.195
|
|
|
|
circadian sleep wake cycle non rem sleep
|
GO:0042748 |
2 |
0.193
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.192
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.190
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.189
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.183
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.183
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.181
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.180
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.179
|
|
|
|
regulation of amine transport
|
GO:0051952 |
21 |
0.179
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.178
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.178
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.177
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.171
|
Mouse |
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.167
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.167
|
Mouse Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.167
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.167
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.155
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.151
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.150
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.148
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.146
|
|
|
|
regulation of circadian sleep wake cycle non rem sleep
|
GO:0045188 |
1 |
0.145
|
|
|
|
norepinephrine secretion
|
GO:0048243 |
2 |
0.145
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.145
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.144
|
Zebrafish |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.142
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
9 |
0.141
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.138
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.138
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.136
|
Zebrafish |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.136
|
|
|
|
response to nicotine
|
GO:0035094 |
6 |
0.134
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.133
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.133
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.132
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.132
|
|
|
|
regulation of norepinephrine secretion
|
GO:0014061 |
2 |
0.130
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.129
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.129
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.129
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.128
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.128
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.128
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.128
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.125
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.124
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.124
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.123
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.121
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.121
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.121
|
Zebrafish |
|
|
monoamine transport
|
GO:0015844 |
33 |
0.120
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.120
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.120
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.118
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.117
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.116
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.115
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.114
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.114
|
Zebrafish |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.113
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.107
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.106
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.104
|
|
|
|
relaxation of muscle
|
GO:0090075 |
18 |
0.104
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.104
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.104
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.102
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.101
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.100
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.100
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.100
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.099
|
Zebrafish |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.098
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.096
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.096
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.095
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.093
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.093
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.092
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.091
|
|
|
|
positive regulation of sodium ion transmembrane transport
|
GO:1902307 |
4 |
0.091
|
|
|
|
lateral geniculate nucleus development
|
GO:0021771 |
1 |
0.090
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.090
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.089
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.089
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.088
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.087
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.087
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.087
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.087
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.085
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.085
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.085
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.084
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.084
|
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
14 |
0.084
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.083
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.083
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.082
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.082
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.082
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.081
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.081
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.080
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.080
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.080
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.079
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.078
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.078
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.077
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.077
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.076
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.076
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.076
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.075
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.075
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.075
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.075
|
|
|
|
baroreceptor response to decreased systemic arterial blood pressure
|
GO:0001982 |
2 |
0.075
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.074
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.073
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.072
|
|
|
|
dopamine metabolic process
|
GO:0042417 |
23 |
0.071
|
|
|
|
regulation of neurotransmitter uptake
|
GO:0051580 |
6 |
0.071
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.071
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.071
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.070
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.070
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.070
|
|
|
|
dopamine transport
|
GO:0015872 |
15 |
0.070
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.070
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.070
|
|
|
|
regulation of dopamine metabolic process
|
GO:0042053 |
10 |
0.069
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.069
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.069
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.068
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.067
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.067
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.067
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.066
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.066
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.066
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.066
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.066
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.066
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.066
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.065
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.065
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.065
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.064
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.064
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.063
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.063
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.062
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.062
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.062
|
|
|
|
sperm motility
|
GO:0030317 |
47 |
0.061
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.061
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.061
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.061
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.060
|
|
|
|
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback
|
GO:0001978 |
5 |
0.060
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.060
|
|
|
|
catecholamine transport
|
GO:0051937 |
21 |
0.059
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.059
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.059
|
|
|
|
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
|
GO:0001988 |
1 |
0.059
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.059
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.058
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.058
|
Fly |
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.058
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.057
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.057
|
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
20 |
0.057
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.057
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.056
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.056
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.056
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.055
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.055
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.055
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.055
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.055
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.055
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.054
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.054
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.053
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.053
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.052
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.052
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.052
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.052
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.052
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.052
|
|
|
|
behavioral response to nutrient
|
GO:0051780 |
1 |
0.051
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.051
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.051
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.050
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.050
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.050
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.050
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.050
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.050
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.050
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.050
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.049
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.049
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.049
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.048
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.048
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.048
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.048
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.048
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.047
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.047
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.047
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.047
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.047
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.046
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.046
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.046
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.046
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.046
|
|
|
|
positive regulation of heart rate
|
GO:0010460 |
10 |
0.046
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.046
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.046
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.045
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.045
|
Fly |
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
20 |
0.045
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.045
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.045
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.045
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.045
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.045
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.044
|
|
|
|
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0014808 |
12 |
0.044
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.044
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
8 |
0.044
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.044
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.044
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.043
|
|
|
|
negative regulation of calcium ion transmembrane transporter activity
|
GO:1901020 |
1 |
0.043
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.043
|
Zebrafish |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.043
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.042
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.042
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.042
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.042
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.042
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.042
|
|
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.041
|
|
|
|
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0010880 |
10 |
0.041
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.041
|
|
|
|
peripheral nervous system axon regeneration
|
GO:0014012 |
2 |
0.041
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.041
|
|
|
|
dopamine uptake
|
GO:0090494 |
4 |
0.041
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.041
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.041
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.041
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.041
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.041
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.040
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.040
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.040
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.040
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.040
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.039
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.039
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.039
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.039
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.039
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
3 |
0.038
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.038
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.038
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.038
|
|
|
|
regulation of systemic arterial blood pressure by baroreceptor feedback
|
GO:0003025 |
7 |
0.038
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.038
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.038
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.038
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.038
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.038
|
|
|
|
regulation of glutamate secretion
|
GO:0014048 |
3 |
0.038
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.037
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.037
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.037
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.037
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.037
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.037
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.036
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.036
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.036
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.036
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.036
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.036
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.036
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.036
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.036
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.035
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.035
|
|
|
|
maintenance of presynaptic active zone structure
|
GO:0048790 |
1 |
0.035
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.035
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.035
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.035
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.035
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.034
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.034
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.034
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.034
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.034
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.034
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.034
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.034
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.033
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.033
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.033
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.033
|
|
|
|
regulation of dopamine uptake involved in synaptic transmission
|
GO:0051584 |
2 |
0.033
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.033
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.033
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.033
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.033
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.033
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.033
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.033
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
2 |
0.032
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.032
|
|
|
|
neurofilament cytoskeleton organization
|
GO:0060052 |
10 |
0.032
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.032
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.032
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.032
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.031
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.031
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.031
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.031
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.031
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.031
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.030
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
26 |
0.030
|
|
|
|
negative regulation of action potential
|
GO:0045759 |
1 |
0.030
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.030
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.030
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.030
|
|
|
|
positive regulation of potassium ion transmembrane transport
|
GO:1901381 |
3 |
0.030
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.030
|
|
|
|
response to food
|
GO:0032094 |
17 |
0.030
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.030
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.029
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.029
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.029
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.029
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.029
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.029
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.029
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
7 |
0.029
|
Worm |
|
|
learning
|
GO:0007612 |
98 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.028
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.028
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.028
|
|
|
|
positive regulation of schwann cell proliferation
|
GO:0010625 |
1 |
0.028
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.028
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.028
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.028
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.028
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.028
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.028
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.028
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.028
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.027
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.027
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.027
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.027
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
22 |
0.027
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
11 |
0.027
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.027
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.027
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.027
|
|
|
|
relaxation of cardiac muscle
|
GO:0055119 |
9 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.027
|
|
|
|
positive regulation of calcium ion transmembrane transporter activity
|
GO:1901021 |
8 |
0.027
|
|
|
|
regulation of gamma aminobutyric acid secretion
|
GO:0014052 |
2 |
0.027
|
|
|
|
neural crest cell migration involved in sympathetic nervous system development
|
GO:1903045 |
1 |
0.026
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.026
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.026
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.026
|
|
|
|
positive regulation of synaptic transmission dopaminergic
|
GO:0032226 |
5 |
0.026
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.026
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.026
|
|
|
|
glycolipid biosynthetic process
|
GO:0009247 |
13 |
0.026
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.026
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.026
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.026
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.026
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.026
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.026
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.025
|
|
|
|
regulation of catecholamine uptake involved in synaptic transmission
|
GO:0051940 |
2 |
0.025
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.025
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.025
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.025
|
|
|
|
schwann cell development
|
GO:0014044 |
22 |
0.025
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.025
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.025
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.025
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
6 |
0.025
|
|
|
|
regulation of catecholamine metabolic process
|
GO:0042069 |
10 |
0.025
|
|
|
|
positive regulation of neurotransmitter transport
|
GO:0051590 |
9 |
0.025
|
|
|
|
membrane repolarization
|
GO:0086009 |
7 |
0.025
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.025
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.025
|
Zebrafish |
|
|
circadian behavior
|
GO:0048512 |
13 |
0.024
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.024
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
21 |
0.024
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.024
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.024
|
|
