Mus musculus

2 known processes

Aco2

aconitase 2, mitochondrial

(Aliases: Aco3,D10Wsu183e,Aco-2)

Aco2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nadh metabolic process GO:0006734 1 1.000
citrate metabolic process GO:0006101 3 0.981
Human Rat
energy derivation by oxidation of organic compounds GO:0015980 77 0.980
Human Rat Fly
tricarboxylic acid metabolic process GO:0072350 5 0.960
Human Rat
generation of precursor metabolites and energy GO:0006091 103 0.931
Human Rat Fly
oxidation reduction process GO:0055114 342 0.924
Human Rat Fly
cellular respiration GO:0045333 38 0.830
Human Rat Fly
coenzyme metabolic process GO:0006732 52 0.817
nucleobase containing small molecule metabolic process GO:0055086 352 0.631
nad metabolic process GO:0019674 7 0.630
aerobic respiration GO:0009060 7 0.389
Human Rat Fly
purine ribonucleotide metabolic process GO:0009150 290 0.370
dicarboxylic acid metabolic process GO:0043648 18 0.357
monocarboxylic acid metabolic process GO:0032787 191 0.316
nucleoside triphosphate metabolic process GO:0009141 230 0.314
mitochondrial electron transport ubiquinol to cytochrome c GO:0006122 2 0.298
succinyl coa metabolic process GO:0006104 1 0.294
proton transport GO:0015992 35 0.246
nucleotide metabolic process GO:0009117 332 0.245
oxidoreduction coenzyme metabolic process GO:0006733 16 0.224
ribose phosphate metabolic process GO:0019693 291 0.210
purine ribonucleoside metabolic process GO:0046128 241 0.206
glycolytic process GO:0006096 20 0.198
nucleoside phosphate metabolic process GO:0006753 338 0.183
nicotinamide nucleotide metabolic process GO:0046496 12 0.169
purine nucleoside metabolic process GO:0042278 241 0.169
pyridine nucleotide metabolic process GO:0019362 12 0.157
hydrogen ion transmembrane transport GO:1902600 25 0.146
cellular amine metabolic process GO:0044106 44 0.138
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.133
atp metabolic process GO:0046034 75 0.130
ribonucleotide metabolic process GO:0009259 291 0.121
cation transport GO:0006812 399 0.114
pigmentation GO:0043473 71 0.111
nucleoside metabolic process GO:0009116 246 0.105
nucleoside monophosphate metabolic process GO:0009123 85 0.095
purine nucleoside triphosphate metabolic process GO:0009144 226 0.092
sulfur compound metabolic process GO:0006790 100 0.091
cellular lipid metabolic process GO:0044255 323 0.086
carbohydrate derivative biosynthetic process GO:1901137 183 0.076
coenzyme biosynthetic process GO:0009108 23 0.071
2 oxoglutarate metabolic process GO:0006103 7 0.069
purine nucleotide metabolic process GO:0006163 302 0.069
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.067
glycosyl compound catabolic process GO:1901658 206 0.067
purine containing compound metabolic process GO:0072521 311 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
thioester metabolic process GO:0035383 19 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.065
carbohydrate metabolic process GO:0005975 230 0.064
cerebellar cortex development GO:0021695 48 0.062
carbohydrate catabolic process GO:0016052 32 0.060
inorganic ion transmembrane transport GO:0098660 234 0.059
atp synthesis coupled electron transport GO:0042773 8 0.059
response to hypoxia GO:0001666 58 0.057
pyridine containing compound metabolic process GO:0072524 14 0.055
ribonucleoside monophosphate metabolic process GO:0009161 80 0.055
cellular amino acid metabolic process GO:0006520 103 0.054
cofactor metabolic process GO:0051186 80 0.053
heterocycle catabolic process GO:0046700 280 0.052
ribonucleoside metabolic process GO:0009119 245 0.051
cellular ketone metabolic process GO:0042180 84 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.048
acyl coa metabolic process GO:0006637 19 0.045
cellular homeostasis GO:0019725 240 0.045
oxidative phosphorylation GO:0006119 14 0.044
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.043
muscle contraction GO:0006936 101 0.043
purine nucleoside monophosphate metabolic process GO:0009126 81 0.043
cation transmembrane transport GO:0098655 266 0.043
purine nucleoside catabolic process GO:0006152 205 0.042
nucleotide catabolic process GO:0009166 217 0.041
aromatic compound catabolic process GO:0019439 286 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
response to organonitrogen compound GO:0010243 246 0.040
cellular ion homeostasis GO:0006873 165 0.039
negative regulation of cell proliferation GO:0008285 296 0.038
inorganic cation transmembrane transport GO:0098662 207 0.038
ribonucleoside catabolic process GO:0042454 206 0.036
nucleoside phosphate biosynthetic process GO:1901293 79 0.036
positive regulation of apoptotic process GO:0043065 217 0.036
glycosyl compound metabolic process GO:1901657 246 0.035
muscle cell development GO:0055001 133 0.035
hydrogen transport GO:0006818 35 0.033
purine nucleoside monophosphate catabolic process GO:0009128 58 0.032
fatty acid metabolic process GO:0006631 121 0.031
endocytosis GO:0006897 168 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
dicarboxylic acid catabolic process GO:0043649 2 0.030
organophosphate catabolic process GO:0046434 232 0.030
myeloid cell homeostasis GO:0002262 114 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
substantia nigra development GO:0021762 2 0.030
midbrain development GO:0030901 35 0.030
positive regulation of hydrolase activity GO:0051345 148 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
nitrogen compound transport GO:0071705 271 0.028
amine metabolic process GO:0009308 45 0.028
glucose homeostasis GO:0042593 128 0.028
positive regulation of proteolysis GO:0045862 85 0.027
nucleoside catabolic process GO:0009164 206 0.027
purine containing compound catabolic process GO:0072523 213 0.027
carbohydrate homeostasis GO:0033500 128 0.027
lipid biosynthetic process GO:0008610 179 0.027
transmembrane transport GO:0055085 412 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
limbic system development GO:0021761 72 0.026
cerebellum development GO:0021549 77 0.026
metanephric glomerular epithelium development GO:0072244 3 0.026
blood vessel morphogenesis GO:0048514 285 0.026
ion transmembrane transport GO:0034220 361 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
muscle system process GO:0003012 141 0.024
positive regulation of cell death GO:0010942 224 0.024
purine ribonucleoside biosynthetic process GO:0046129 19 0.024
homeostasis of number of cells GO:0048872 210 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of cell development GO:0010720 237 0.023
metanephric glomerular endothelium development GO:0072264 1 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
small molecule catabolic process GO:0044282 71 0.023
metencephalon development GO:0022037 89 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
regulation of cytokine production GO:0001817 266 0.022
fatty acid oxidation GO:0019395 28 0.022
olfactory lobe development GO:0021988 32 0.022
mitotic cell cycle GO:0000278 195 0.021
striated muscle contraction GO:0006941 45 0.021
positive regulation of atp biosynthetic process GO:2001171 2 0.021
regulation of endopeptidase activity GO:0052548 89 0.021
purine nucleoside triphosphate biosynthetic process GO:0009145 7 0.021
digestive tract morphogenesis GO:0048546 147 0.020
apoptotic signaling pathway GO:0097190 306 0.020
cation homeostasis GO:0055080 212 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
epithelial cell proliferation GO:0050673 174 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
transmission of nerve impulse GO:0019226 76 0.019
action potential GO:0001508 78 0.019
multicellular organismal signaling GO:0035637 91 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
mesoderm development GO:0007498 100 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
regulation of hormone levels GO:0010817 211 0.018
positive regulation of neuron projection development GO:0010976 79 0.018
pyruvate metabolic process GO:0006090 28 0.018
substrate dependent cell migration GO:0006929 18 0.018
response to peptide GO:1901652 136 0.018
epithelial cell development GO:0002064 159 0.018
synaptic transmission GO:0007268 329 0.018
positive regulation of peptide hormone secretion GO:0090277 31 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
axonogenesis GO:0007409 274 0.018
formation of primary germ layer GO:0001704 77 0.018
small molecule biosynthetic process GO:0044283 132 0.017
atp catabolic process GO:0006200 55 0.017
forebrain generation of neurons GO:0021872 63 0.017
regulation of hydrolase activity GO:0051336 246 0.017
sensory organ morphogenesis GO:0090596 242 0.017
myosin filament organization GO:0031033 3 0.017
organic acid biosynthetic process GO:0016053 86 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
neuronal action potential GO:0019228 54 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of neuron death GO:1901214 134 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
endothelial cell proliferation GO:0001935 27 0.016
angiogenesis GO:0001525 201 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
purine nucleoside biosynthetic process GO:0042451 19 0.016
forebrain cell migration GO:0021885 58 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
hexose catabolic process GO:0019320 3 0.016
leukocyte differentiation GO:0002521 342 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
multicellular organismal aging GO:0010259 24 0.015
regulation of secretion by cell GO:1903530 249 0.015
neuron neuron synaptic transmission GO:0007270 69 0.015
myeloid cell differentiation GO:0030099 233 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
digestive tract development GO:0048565 190 0.015
diencephalon development GO:0021536 63 0.015
glycoprotein metabolic process GO:0009100 116 0.015
mesoderm morphogenesis GO:0048332 64 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
neural tube formation GO:0001841 108 0.014
monosaccharide metabolic process GO:0005996 106 0.014
anatomical structure homeostasis GO:0060249 145 0.014
peptidyl amino acid modification GO:0018193 336 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
placenta development GO:0001890 140 0.014
acyl coa biosynthetic process GO:0071616 7 0.014
olfactory bulb development GO:0021772 30 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cell adhesion GO:0007155 329 0.014
regulation of branching involved in salivary gland morphogenesis by epithelial mesenchymal signaling GO:0060683 1 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
quinone biosynthetic process GO:1901663 4 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.013
skin development GO:0043588 220 0.013
purine nucleotide biosynthetic process GO:0006164 65 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
urogenital system development GO:0001655 261 0.013
chemotaxis GO:0006935 247 0.013
response to starvation GO:0042594 65 0.013
response to nutrient levels GO:0031667 109 0.013
regulation of cell activation GO:0050865 289 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
maintenance of location GO:0051235 89 0.013
cellularization GO:0007349 1 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
positive regulation of oocyte development GO:0060282 4 0.013
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
forebrain development GO:0030900 302 0.013
epidermis development GO:0008544 187 0.013
myelination GO:0042552 74 0.013
forebrain neuron differentiation GO:0021879 52 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
regulation of protein localization GO:0032880 231 0.013
central nervous system neuron development GO:0021954 67 0.013
regulation of multi organism process GO:0043900 111 0.013
protein localization to nucleus GO:0034504 121 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
response to oxidative stress GO:0006979 123 0.013
cell maturation GO:0048469 127 0.013
neuron death GO:0070997 154 0.013
nucleoside biosynthetic process GO:0009163 21 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
oocyte axis specification GO:0007309 2 0.012
developmental maturation GO:0021700 193 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.012
cellular chemical homeostasis GO:0055082 215 0.012
protein acylation GO:0043543 64 0.012
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.012
cytoplasmic transport GO:0016482 234 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of kinase activity GO:0043549 249 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
hippocampus development GO:0021766 52 0.012
positive regulation of hormone secretion GO:0046887 38 0.012
cellular protein complex assembly GO:0043623 116 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of cellular response to stress GO:0080135 159 0.011
positive regulation of protein modification process GO:0031401 299 0.011
response to oxygen levels GO:0070482 62 0.011
protein targeting to membrane GO:0006612 20 0.011
ensheathment of neurons GO:0007272 76 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of endothelial cell proliferation GO:0001936 23 0.011
regulation of proteolysis GO:0030162 164 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
regulation of ion transport GO:0043269 215 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
glycosyl compound biosynthetic process GO:1901659 21 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
negative regulation of molecular function GO:0044092 258 0.011
peptide transport GO:0015833 133 0.011
mitochondrial membrane organization GO:0007006 26 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of neuron differentiation GO:0045664 281 0.011
muscle tissue development GO:0060537 308 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
regulation of secretion GO:0051046 274 0.010
rhodopsin mediated signaling pathway GO:0016056 4 0.010
response to decreased oxygen levels GO:0036293 59 0.010
activation of cysteine type endopeptidase activity GO:0097202 27 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
anion transport GO:0006820 177 0.010
peptide hormone secretion GO:0030072 109 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
synapse organization GO:0050808 125 0.010
lipid oxidation GO:0034440 29 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
inflammatory response GO:0006954 244 0.010

Aco2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.092
disease of cellular proliferation DOID:14566 0 0.092
sensory system disease DOID:0050155 0 0.036
disease of anatomical entity DOID:7 0 0.036
Human
eye and adnexa disease DOID:1492 0 0.036
nervous system disease DOID:863 0 0.036
Human
eye disease DOID:5614 0 0.036
organ system cancer DOID:0050686 0 0.036
retinal disease DOID:5679 0 0.025
central nervous system disease DOID:331 0 0.018
Human
neurodegenerative disease DOID:1289 0 0.018
Human
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
immune system disease DOID:2914 0 0.013
endocrine gland cancer DOID:170 0 0.013
retinal degeneration DOID:8466 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
hematopoietic system disease DOID:74 0 0.011
phaeochromocytoma DOID:0050771 0 0.010
cell type benign neoplasm DOID:0060084 0 0.010
benign neoplasm DOID:0060072 0 0.010