Mus musculus

0 known processes

Acot2

acyl-CoA thioesterase 2

(Aliases: Mte1,AA571646,MTE-I)

Acot2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
saturated monocarboxylic acid metabolic process GO:0032788 2 0.532
Mouse
very long chain fatty acid catabolic process GO:0042760 2 0.418
Rat
small molecule catabolic process GO:0044282 71 0.377
Rat
acyl coa metabolic process GO:0006637 19 0.328
Human Mouse Rat
cellular lipid catabolic process GO:0044242 52 0.310
Rat
fatty acid metabolic process GO:0006631 121 0.302
Human Mouse Rat
thioester metabolic process GO:0035383 19 0.259
Human Mouse Rat
monocarboxylic acid metabolic process GO:0032787 191 0.253
Human Mouse Rat
cofactor metabolic process GO:0051186 80 0.181
Human Mouse Rat
organic acid catabolic process GO:0016054 51 0.179
Rat
oxidation reduction process GO:0055114 342 0.172
cellular lipid metabolic process GO:0044255 323 0.160
Human Mouse Rat
carboxylic acid catabolic process GO:0046395 51 0.157
Rat
organic hydroxy compound metabolic process GO:1901615 203 0.151
Mouse
very long chain fatty acid metabolic process GO:0000038 8 0.143
Human Mouse Rat
fatty acid catabolic process GO:0009062 25 0.142
Rat
cellular ketone metabolic process GO:0042180 84 0.141
coenzyme metabolic process GO:0006732 52 0.129
Human Mouse Rat
short chain fatty acid metabolic process GO:0046459 6 0.119
Mouse
sulfur compound metabolic process GO:0006790 100 0.105
Human Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.095
lipid biosynthetic process GO:0008610 179 0.089
steroid metabolic process GO:0008202 119 0.083
Mouse
fatty acid oxidation GO:0019395 28 0.078
cellular amino acid metabolic process GO:0006520 103 0.072
cellular amine metabolic process GO:0044106 44 0.069
transmembrane transport GO:0055085 412 0.064
lipid modification GO:0030258 65 0.063
amine metabolic process GO:0009308 45 0.061
lipid catabolic process GO:0016042 69 0.060
Rat
ion transmembrane transport GO:0034220 361 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.057
response to nutrient levels GO:0031667 109 0.056
Rat
anion transport GO:0006820 177 0.056
long chain fatty acid metabolic process GO:0001676 26 0.056
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.053
cation transport GO:0006812 399 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
response to extracellular stimulus GO:0009991 127 0.045
Rat
organic anion transport GO:0015711 137 0.044
lipid oxidation GO:0034440 29 0.044
response to epidermal growth factor GO:0070849 4 0.042
Rat
monocarboxylic acid catabolic process GO:0072329 27 0.041
Rat
ribonucleoside metabolic process GO:0009119 245 0.040
nucleotide metabolic process GO:0009117 332 0.040
nitrogen compound transport GO:0071705 271 0.039
cation transmembrane transport GO:0098655 266 0.038
nucleoside metabolic process GO:0009116 246 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
small molecule biosynthetic process GO:0044283 132 0.037
purine containing compound metabolic process GO:0072521 311 0.035
response to drug GO:0042493 75 0.034
Rat
carbohydrate metabolic process GO:0005975 230 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
organic acid biosynthetic process GO:0016053 86 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
carboxylic acid transport GO:0046942 100 0.032
aromatic compound catabolic process GO:0019439 286 0.031
response to organonitrogen compound GO:0010243 246 0.031
alcohol metabolic process GO:0006066 116 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
response to growth factor GO:0070848 198 0.030
Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
glycerolipid metabolic process GO:0046486 122 0.028
organic acid transport GO:0015849 101 0.028
multicellular organismal signaling GO:0035637 91 0.027
heterocycle catabolic process GO:0046700 280 0.027
cation homeostasis GO:0055080 212 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
cellular chemical homeostasis GO:0055082 215 0.027
regulation of membrane potential GO:0042391 192 0.027
carboxylic acid biosynthetic process GO:0046394 86 0.027
organic cyclic compound catabolic process GO:1901361 295 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
anion transmembrane transport GO:0098656 71 0.026
acylglycerol metabolic process GO:0006639 55 0.026
ras protein signal transduction GO:0007265 77 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
organophosphate catabolic process GO:0046434 232 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
cellular homeostasis GO:0019725 240 0.024
positive regulation of protein modification process GO:0031401 299 0.024
purine containing compound catabolic process GO:0072523 213 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
mitochondrion organization GO:0007005 134 0.023
regulation of fatty acid oxidation GO:0046320 10 0.023
apoptotic signaling pathway GO:0097190 306 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
actin cytoskeleton organization GO:0030036 220 0.023
negative regulation of molecular function GO:0044092 258 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
regulation of hydrolase activity GO:0051336 246 0.022
fatty acid beta oxidation GO:0006635 16 0.022
action potential GO:0001508 78 0.022
regulation of organelle organization GO:0033043 289 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
macromolecule catabolic process GO:0009057 281 0.022
response to hypoxia GO:0001666 58 0.022
Rat
nucleoside phosphate catabolic process GO:1901292 222 0.022
glycosyl compound catabolic process GO:1901658 206 0.021
striated muscle tissue development GO:0014706 293 0.021
muscle tissue development GO:0060537 308 0.021
membrane organization GO:0061024 245 0.021
nucleotide catabolic process GO:0009166 217 0.021
regulation of homeostatic process GO:0032844 182 0.021
amino acid transmembrane transport GO:0003333 37 0.020
cytoplasmic transport GO:0016482 234 0.020
response to organic cyclic compound GO:0014070 198 0.020
maintenance of location GO:0051235 89 0.020
neutral lipid metabolic process GO:0006638 57 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
peptidyl amino acid modification GO:0018193 336 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of hormone levels GO:0010817 211 0.020
rho protein signal transduction GO:0007266 32 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
bile acid metabolic process GO:0008206 17 0.019
Mouse
regulation of ion transport GO:0043269 215 0.019
transmission of nerve impulse GO:0019226 76 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
cellular ion homeostasis GO:0006873 165 0.019
nucleoside catabolic process GO:0009164 206 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
response to oxygen levels GO:0070482 62 0.019
Rat
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
regulation of fatty acid metabolic process GO:0019217 28 0.019
cytokine production GO:0001816 319 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
regulation of cell activation GO:0050865 289 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of secretion GO:0051046 274 0.018
neuronal action potential GO:0019228 54 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
regulation of kinase activity GO:0043549 249 0.018
lipid transport GO:0006869 98 0.018
dephosphorylation GO:0016311 129 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
skin development GO:0043588 220 0.018
regulation of protein kinase activity GO:0045859 232 0.018
forebrain development GO:0030900 302 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of protein localization GO:0032880 231 0.017
leukocyte differentiation GO:0002521 342 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
regulation of cytokine production GO:0001817 266 0.017
cellular response to lipid GO:0071396 145 0.017
hexose metabolic process GO:0019318 98 0.017
purine nucleotide catabolic process GO:0006195 211 0.016
monosaccharide metabolic process GO:0005996 106 0.016
positive regulation of fatty acid oxidation GO:0046321 4 0.016
circulatory system process GO:0003013 197 0.016
organic hydroxy compound transport GO:0015850 93 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
blood circulation GO:0008015 195 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
response to acid chemical GO:0001101 111 0.016
regulation of system process GO:0044057 200 0.016
amino acid transport GO:0006865 61 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
sterol homeostasis GO:0055092 45 0.015
positive regulation of cell death GO:0010942 224 0.015
monocarboxylic acid transport GO:0015718 44 0.015
protein localization to organelle GO:0033365 185 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
mapk cascade GO:0000165 281 0.015
myeloid cell differentiation GO:0030099 233 0.015
cell adhesion GO:0007155 329 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
lipid homeostasis GO:0055088 63 0.015
regulation of secretion by cell GO:1903530 249 0.015
phospholipid metabolic process GO:0006644 87 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of neuron differentiation GO:0045664 281 0.015
spermatogenesis GO:0007283 284 0.015
response to peptide hormone GO:0043434 127 0.015
carnitine metabolic process GO:0009437 7 0.015
long chain fatty acid import GO:0044539 2 0.015
intracellular protein transport GO:0006886 204 0.015
innate immune response GO:0045087 157 0.015
lipid localization GO:0010876 126 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of transferase activity GO:0051338 263 0.014
anatomical structure homeostasis GO:0060249 145 0.014
cellular modified amino acid metabolic process GO:0006575 63 0.014
response to lipopolysaccharide GO:0032496 128 0.014
nuclear transport GO:0051169 139 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of lipid biosynthetic process GO:0046890 54 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
response to peptide GO:1901652 136 0.014
organelle localization GO:0051640 179 0.014
amide transport GO:0042886 138 0.014
carbohydrate biosynthetic process GO:0016051 74 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
positive regulation of nervous system development GO:0051962 221 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
renal system development GO:0072001 225 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
metal ion homeostasis GO:0055065 189 0.013
protein catabolic process GO:0030163 221 0.013
locomotory behavior GO:0007626 195 0.013
divalent inorganic cation transport GO:0072511 178 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of anatomical structure size GO:0090066 178 0.013
sensory perception GO:0007600 245 0.013
protein localization to membrane GO:0072657 108 0.013
cellular amide metabolic process GO:0043603 58 0.013
glucose metabolic process GO:0006006 92 0.013
glycerolipid biosynthetic process GO:0045017 50 0.013
male gamete generation GO:0048232 285 0.013
response to oxidative stress GO:0006979 123 0.013
protein localization to nucleus GO:0034504 121 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cell type specific apoptotic process GO:0097285 268 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
ossification GO:0001503 216 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
blood vessel morphogenesis GO:0048514 285 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
endocytosis GO:0006897 168 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
microtubule based process GO:0007017 236 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
regulation of intracellular transport GO:0032386 159 0.012
gtp metabolic process GO:0046039 144 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
response to insulin GO:0032868 100 0.012
single organism nuclear import GO:1902593 95 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of defense response GO:0031347 233 0.012
cholesterol metabolic process GO:0008203 56 0.012
protein maturation GO:0051604 176 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
homeostasis of number of cells GO:0048872 210 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of cell cycle GO:0051726 281 0.012
actin filament organization GO:0007015 113 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
skeletal system development GO:0001501 356 0.012
immune effector process GO:0002252 321 0.012
positive regulation of cell development GO:0010720 237 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
multicellular organism growth GO:0035264 161 0.012
inflammatory response GO:0006954 244 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
cellular protein complex assembly GO:0043623 116 0.012
negative regulation of protein modification process GO:0031400 163 0.011
triglyceride metabolic process GO:0006641 51 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
protein targeting GO:0006605 143 0.011
muscle system process GO:0003012 141 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
wnt signaling pathway GO:0016055 188 0.011
response to radiation GO:0009314 165 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of mapk cascade GO:0043408 248 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of cell motility GO:2000145 236 0.011
divalent metal ion transport GO:0070838 172 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
calcium ion transport GO:0006816 159 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
c4 dicarboxylate transport GO:0015740 3 0.011
adiponectin activated signaling pathway GO:0033211 4 0.011
endomembrane system organization GO:0010256 147 0.011
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.011
nuclear import GO:0051170 95 0.011
tissue remodeling GO:0048771 102 0.011
negative regulation of immune system process GO:0002683 209 0.011
sequestering of calcium ion GO:0051208 18 0.011
negative regulation of organelle organization GO:0010639 90 0.011
kidney development GO:0001822 213 0.011
regulation of response to wounding GO:1903034 189 0.011
compound eye development GO:0048749 1 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
protein import GO:0017038 101 0.011
epithelial cell development GO:0002064 159 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
mitochondrion distribution GO:0048311 4 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
stem cell differentiation GO:0048863 268 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
synaptic transmission GO:0007268 329 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
wound healing GO:0042060 157 0.010
response to steroid hormone GO:0048545 56 0.010
sequestering of metal ion GO:0051238 19 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
cholesterol homeostasis GO:0042632 44 0.010
protein oligomerization GO:0051259 67 0.010
negative regulation of transferase activity GO:0051348 85 0.010
rna interference GO:0016246 2 0.010
positive regulation of homeostatic process GO:0032846 64 0.010
positive regulation of organelle organization GO:0010638 128 0.010
regulation of phospholipid biosynthetic process GO:0071071 3 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
glucose homeostasis GO:0042593 128 0.010
protein ubiquitination GO:0016567 171 0.010
hormone metabolic process GO:0042445 86 0.010
diterpenoid metabolic process GO:0016101 24 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
amino acid betaine metabolic process GO:0006577 7 0.010
methylation GO:0032259 134 0.010
angiogenesis GO:0001525 201 0.010

Acot2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019
inherited metabolic disorder DOID:655 0 0.017
immune system disease DOID:2914 0 0.012
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010