Mus musculus

134 known processes

Acvr2a

activin receptor IIA

(Aliases: TactrII,ActrIIa,Acvr2)

Acvr2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
insulin secretion GO:0030073 89 0.649
Mouse
urogenital system development GO:0001655 261 0.531
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.496
Mouse
regulation of activin receptor signaling pathway GO:0032925 10 0.467
Human
mesoderm development GO:0007498 100 0.459
activin receptor signaling pathway GO:0032924 18 0.454
Human Rat
positive regulation of protein phosphorylation GO:0001934 242 0.443
Human Mouse
bmp signaling pathway GO:0030509 93 0.403
amide transport GO:0042886 138 0.398
Mouse
renal system development GO:0072001 225 0.392
Mouse
regulation of neuron projection development GO:0010975 169 0.386
t cell activation GO:0042110 289 0.377
regulation of hormone levels GO:0010817 211 0.375
Mouse Rat
peptide secretion GO:0002790 114 0.368
Mouse
mapk cascade GO:0000165 281 0.366
positive regulation of protein modification process GO:0031401 299 0.348
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.341
regulation of neuron differentiation GO:0045664 281 0.340
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.335
kidney development GO:0001822 213 0.334
Mouse
peptide hormone secretion GO:0030072 109 0.332
Mouse
myeloid cell differentiation GO:0030099 233 0.305
Human
cellular response to growth factor stimulus GO:0071363 197 0.303
Human
epithelial tube morphogenesis GO:0060562 303 0.297
skeletal system development GO:0001501 356 0.290
peptide transport GO:0015833 133 0.283
Mouse
leukocyte differentiation GO:0002521 342 0.281
regulation of cellular amino acid metabolic process GO:0006521 5 0.279
hormone secretion GO:0046879 128 0.272
Mouse Rat
regulation of anatomical structure size GO:0090066 178 0.270
chemotaxis GO:0006935 247 0.269
cell adhesion GO:0007155 329 0.269
regulation of kinase activity GO:0043549 249 0.265
Mouse
positive regulation of activin receptor signaling pathway GO:0032927 3 0.263
Human
regulation of secretion GO:0051046 274 0.260
Rat
positive regulation of neuron differentiation GO:0045666 141 0.260
camera type eye development GO:0043010 266 0.259
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.259
mesenchyme development GO:0060485 152 0.255
Zebrafish
homeostasis of number of cells GO:0048872 210 0.240
Human
epithelial cell proliferation GO:0050673 174 0.232
positive regulation of transferase activity GO:0051347 167 0.231
Mouse
positive regulation of cell development GO:0010720 237 0.229
negative regulation of cell proliferation GO:0008285 296 0.228
regulation of cellular amine metabolic process GO:0033238 20 0.226
regulation of cellular component biogenesis GO:0044087 181 0.225
regulation of cell projection organization GO:0031344 206 0.220
determination of left right symmetry GO:0007368 80 0.219
inflammatory response GO:0006954 244 0.217
cellular amine metabolic process GO:0044106 44 0.217
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.212
sperm ejaculation GO:0042713 1 0.207
positive regulation of cell projection organization GO:0031346 95 0.206
palate development GO:0060021 76 0.203
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.203
cellular ketone metabolic process GO:0042180 84 0.199
regulation of cell activation GO:0050865 289 0.197
cellular amino acid metabolic process GO:0006520 103 0.196
epidermis development GO:0008544 187 0.194
regulation of protein kinase activity GO:0045859 232 0.190
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.187
regulation of protein localization GO:0032880 231 0.187
cartilage development GO:0051216 140 0.184
Zebrafish
regulation of mapk cascade GO:0043408 248 0.184
circulatory system process GO:0003013 197 0.181
ossification GO:0001503 216 0.180
Human
digestive tract development GO:0048565 190 0.178
amine metabolic process GO:0009308 45 0.174
response to sterol GO:0036314 4 0.173
multicellular organism growth GO:0035264 161 0.171
spermatogenesis GO:0007283 284 0.171
regulation of bmp signaling pathway GO:0030510 60 0.170
respiratory tube development GO:0030323 167 0.169
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.166
peptidyl amino acid modification GO:0018193 336 0.164
regulation of cellular component size GO:0032535 121 0.163
positive regulation of nervous system development GO:0051962 221 0.161
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.159
morphogenesis of embryonic epithelium GO:0016331 159 0.158
digestive system development GO:0055123 200 0.158
sensory organ morphogenesis GO:0090596 242 0.155
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.155
gland development GO:0048732 330 0.154
skeletal system morphogenesis GO:0048705 203 0.154
Mouse
cytoplasmic transport GO:0016482 234 0.153
regulation of t cell activation GO:0050863 170 0.149
negative regulation of phosphorus metabolic process GO:0010563 184 0.148
negative regulation of synapse assembly GO:0051964 3 0.148
myeloid leukocyte differentiation GO:0002573 119 0.147
positive regulation of mapk cascade GO:0043410 170 0.145
response to monosaccharide GO:0034284 67 0.144
Mouse
tissue remodeling GO:0048771 102 0.143
Mouse
metal ion homeostasis GO:0055065 189 0.143
female gamete generation GO:0007292 74 0.142
heart morphogenesis GO:0003007 178 0.142
regulation of lymphocyte activation GO:0051249 240 0.142
cation homeostasis GO:0055080 212 0.140
skin development GO:0043588 220 0.139
venous blood vessel development GO:0060841 13 0.139
Mouse
response to organonitrogen compound GO:0010243 246 0.138
stem cell development GO:0048864 219 0.138
Zebrafish
germ cell development GO:0007281 185 0.137
blood vessel morphogenesis GO:0048514 285 0.133
regulation of transferase activity GO:0051338 263 0.133
Mouse
t cell differentiation GO:0030217 174 0.130
negative regulation of phosphate metabolic process GO:0045936 184 0.128
ubiquitin dependent protein catabolic process GO:0006511 129 0.127
regulation of leukocyte differentiation GO:1902105 159 0.126
neuron projection guidance GO:0097485 141 0.126
response to growth factor GO:0070848 198 0.125
Human
cellular homeostasis GO:0019725 240 0.125
cellular protein catabolic process GO:0044257 155 0.125
positive regulation of programmed cell death GO:0043068 218 0.124
cytokine production GO:0001816 319 0.121
regulation of cellular ketone metabolic process GO:0010565 66 0.121
mesendoderm development GO:0048382 3 0.120
small gtpase mediated signal transduction GO:0007264 97 0.119
blood vessel remodeling GO:0001974 33 0.119
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.117
Human
hindbrain development GO:0030902 128 0.117
Zebrafish
endocrine system development GO:0035270 98 0.115
striated muscle tissue development GO:0014706 293 0.115
protein ubiquitination GO:0016567 171 0.114
single organismal cell cell adhesion GO:0016337 131 0.113
positive regulation of cellular amine metabolic process GO:0033240 5 0.113
stem cell differentiation GO:0048863 268 0.113
Zebrafish
regulation of defense response GO:0031347 233 0.112
protein modification by small protein conjugation GO:0032446 187 0.112
organonitrogen compound catabolic process GO:1901565 264 0.110
metencephalon development GO:0022037 89 0.109
regulation of cellular catabolic process GO:0031329 242 0.109
regulation of secretion by cell GO:1903530 249 0.109
Rat
b cell activation GO:0042113 161 0.106
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.106
intracellular protein transport GO:0006886 204 0.106
endoderm development GO:0007492 45 0.105
negative regulation of protein metabolic process GO:0051248 282 0.105
positive regulation of neuron projection development GO:0010976 79 0.105
negative regulation of immune system process GO:0002683 209 0.104
neural tube development GO:0021915 160 0.102
endocytosis GO:0006897 168 0.102
male gamete generation GO:0048232 285 0.101
positive regulation of kinase activity GO:0033674 155 0.100
Mouse
organ growth GO:0035265 117 0.100
Mouse
regulation of cell migration GO:0030334 219 0.099
dna metabolic process GO:0006259 303 0.099
blood circulation GO:0008015 195 0.097
regulation of intracellular transport GO:0032386 159 0.097
mesenchymal cell development GO:0014031 93 0.097
Zebrafish
negative regulation of phosphorylation GO:0042326 166 0.096
gastrulation GO:0007369 116 0.096
regulation of organ morphogenesis GO:2000027 144 0.096
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.096
single organism cell adhesion GO:0098602 156 0.095
synapse organization GO:0050808 125 0.095
modification dependent protein catabolic process GO:0019941 133 0.094
nitrogen compound transport GO:0071705 271 0.094
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.094
regulation of establishment of protein localization GO:0070201 181 0.093
positive regulation of cell activation GO:0050867 158 0.093
mesenchymal cell differentiation GO:0048762 107 0.092
Zebrafish
cellular chemical homeostasis GO:0055082 215 0.092
regulation of cytokine production GO:0001817 266 0.092
respiratory system development GO:0060541 190 0.092
Mouse
axonogenesis GO:0007409 274 0.092
digestive tract morphogenesis GO:0048546 147 0.091
erythrocyte differentiation GO:0030218 88 0.090
Human
axon guidance GO:0007411 141 0.089
regulation of protein serine threonine kinase activity GO:0071900 157 0.089
response to molecule of bacterial origin GO:0002237 143 0.087
negative regulation of nervous system development GO:0051961 156 0.086
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.085
response to organic cyclic compound GO:0014070 198 0.084
developmental maturation GO:0021700 193 0.083
regulation of reproductive process GO:2000241 66 0.083
somitogenesis GO:0001756 69 0.082
negative regulation of protein modification process GO:0031400 163 0.082
endothelial cell differentiation GO:0045446 41 0.082
Mouse
meiotic cell cycle GO:0051321 122 0.082
pancreas development GO:0031016 57 0.081
Mouse
cellular response to lipid GO:0071396 145 0.081
regulation of osteoblast differentiation GO:0045667 67 0.081
Human
peptidyl serine phosphorylation GO:0018105 74 0.081
embryonic epithelial tube formation GO:0001838 130 0.081
maintenance of location GO:0051235 89 0.080
positive regulation of cellular component biogenesis GO:0044089 94 0.080
embryonic skeletal system development GO:0048706 120 0.079
negative regulation of cellular protein metabolic process GO:0032269 247 0.079
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.079
lymphocyte proliferation GO:0046651 164 0.079
leukocyte proliferation GO:0070661 172 0.079
protein targeting GO:0006605 143 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.078
kidney epithelium development GO:0072073 121 0.078
muscle system process GO:0003012 141 0.077
apoptotic signaling pathway GO:0097190 306 0.077
morphogenesis of a branching structure GO:0001763 203 0.077
positive regulation of ossification GO:0045778 47 0.076
Human
odontogenesis GO:0042476 78 0.076
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.076
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.075
connective tissue development GO:0061448 179 0.075
Zebrafish
response to insulin GO:0032868 100 0.074
formation of primary germ layer GO:0001704 77 0.074
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.073
peptidyl serine modification GO:0018209 83 0.073
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.073
lipid localization GO:0010876 126 0.072
cell growth GO:0016049 130 0.072
cation transport GO:0006812 399 0.072
heterocycle catabolic process GO:0046700 280 0.071
regulation of ion transport GO:0043269 215 0.071
regulation of homeostatic process GO:0032844 182 0.071
Human
ameboidal type cell migration GO:0001667 128 0.070
Zebrafish
mammary gland morphogenesis GO:0060443 54 0.070
cellular metal ion homeostasis GO:0006875 151 0.070
regionalization GO:0003002 337 0.070
ras protein signal transduction GO:0007265 77 0.070
stress activated mapk cascade GO:0051403 80 0.070
regulation of lymphocyte proliferation GO:0050670 117 0.070
positive regulation of cellular catabolic process GO:0031331 148 0.069
positive regulation of apoptotic signaling pathway GO:2001235 95 0.069
wnt signaling pathway GO:0016055 188 0.069
adaptive immune response GO:0002250 155 0.068
regulation of protein transport GO:0051223 163 0.068
response to transforming growth factor beta GO:0071559 88 0.068
guanosine containing compound metabolic process GO:1901068 144 0.068
modification dependent macromolecule catabolic process GO:0043632 133 0.068
jnk cascade GO:0007254 72 0.068
positive regulation of reproductive process GO:2000243 19 0.068
ribonucleotide metabolic process GO:0009259 291 0.068
response to lipopolysaccharide GO:0032496 128 0.068
forebrain development GO:0030900 302 0.068
regulation of inflammatory response GO:0050727 147 0.067
lipid biosynthetic process GO:0008610 179 0.067
cognition GO:0050890 149 0.067
regulation of vesicle mediated transport GO:0060627 139 0.067
neural tube formation GO:0001841 108 0.067
response to cholesterol GO:0070723 4 0.067
neural crest cell differentiation GO:0014033 54 0.067
Zebrafish
regulation of cell adhesion GO:0030155 154 0.066
response to peptide GO:1901652 136 0.066
positive regulation of growth GO:0045927 104 0.066
regulation of response to wounding GO:1903034 189 0.066
regulation of cell motility GO:2000145 236 0.066
lymphocyte differentiation GO:0030098 242 0.065
extrinsic apoptotic signaling pathway GO:0097191 126 0.065
t cell proliferation GO:0042098 120 0.065
establishment of protein localization to organelle GO:0072594 118 0.064
appendage development GO:0048736 166 0.064
regulation of muscle tissue development GO:1901861 97 0.064
retina development in camera type eye GO:0060041 119 0.064
Mouse
limb morphogenesis GO:0035108 149 0.063
cellular ion homeostasis GO:0006873 165 0.063
positive regulation of cell migration GO:0030335 109 0.063
angiogenesis GO:0001525 201 0.063
ribonucleoside triphosphate metabolic process GO:0009199 220 0.063
negative regulation of cellular amine metabolic process GO:0033239 1 0.062
establishment of organelle localization GO:0051656 122 0.062
regulation of organelle organization GO:0033043 289 0.062
positive regulation of protein transport GO:0051222 93 0.061
embryonic heart tube morphogenesis GO:0003143 51 0.061
peptidyl threonine modification GO:0018210 31 0.061
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.061
gastrulation with mouth forming second GO:0001702 29 0.061
regulation of multi organism process GO:0043900 111 0.061
positive regulation of cell cycle GO:0045787 92 0.061
organic cyclic compound catabolic process GO:1901361 295 0.061
regulation of t cell differentiation GO:0045580 83 0.060
primary neural tube formation GO:0014020 95 0.060
protein catabolic process GO:0030163 221 0.060
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.060
negative regulation of protein phosphorylation GO:0001933 126 0.060
lung development GO:0030324 164 0.059
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.059
regulation of ras protein signal transduction GO:0046578 114 0.059
mammary gland epithelium development GO:0061180 65 0.059
biomineral tissue development GO:0031214 64 0.058
Human
bone development GO:0060348 120 0.058
nucleoside metabolic process GO:0009116 246 0.058
purine containing compound metabolic process GO:0072521 311 0.057
cellular response to organonitrogen compound GO:0071417 145 0.057
developmental cell growth GO:0048588 84 0.057
central nervous system neuron differentiation GO:0021953 162 0.057
divalent inorganic cation homeostasis GO:0072507 138 0.057
single organism nuclear import GO:1902593 95 0.057
muscle contraction GO:0006936 101 0.057
neural tube closure GO:0001843 90 0.057
male gonad development GO:0008584 88 0.057
innate immune response GO:0045087 157 0.057
development of primary sexual characteristics GO:0045137 143 0.056
ribonucleoside metabolic process GO:0009119 245 0.056
fat cell differentiation GO:0045444 160 0.056
canonical wnt signaling pathway GO:0060070 130 0.056
ribonucleoside catabolic process GO:0042454 206 0.056
embryonic heart tube development GO:0035050 65 0.056
positive regulation of cell death GO:0010942 224 0.055
peptidyl threonine phosphorylation GO:0018107 31 0.055
retina vasculature development in camera type eye GO:0061298 17 0.055
Mouse
cellular response to hormone stimulus GO:0032870 150 0.054
transmembrane transport GO:0055085 412 0.054
regulation of nucleoside metabolic process GO:0009118 130 0.054
muscle tissue development GO:0060537 308 0.054
cell substrate adhesion GO:0031589 130 0.054
positive regulation of map kinase activity GO:0043406 84 0.054
regulation of leukocyte proliferation GO:0070663 121 0.054
myeloid cell homeostasis GO:0002262 114 0.054
Human
smad protein signal transduction GO:0060395 21 0.053
lymphocyte homeostasis GO:0002260 64 0.053
regulation of cytoplasmic transport GO:1903649 112 0.053
regulation of blood circulation GO:1903522 93 0.053
regulation of epithelial cell proliferation GO:0050678 141 0.053
immune response regulating signaling pathway GO:0002764 125 0.053
gtp metabolic process GO:0046039 144 0.053
regulation of cell size GO:0008361 72 0.053
positive regulation of lymphocyte activation GO:0051251 140 0.052
regulation of cell cycle GO:0051726 281 0.052
regulation of wnt signaling pathway GO:0030111 123 0.052
memory GO:0007613 58 0.052
microtubule based process GO:0007017 236 0.052
regulation of protein catabolic process GO:0042176 108 0.052
defense response to other organism GO:0098542 197 0.052
cardiac chamber morphogenesis GO:0003206 93 0.052
embryonic skeletal system morphogenesis GO:0048704 91 0.052
leukocyte homeostasis GO:0001776 79 0.052
regulation of nucleocytoplasmic transport GO:0046822 73 0.052
regulation of gtp catabolic process GO:0033124 113 0.051
tolerance induction to self antigen GO:0002513 4 0.051
olfactory learning GO:0008355 2 0.051
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.051
negative regulation of lymphocyte activation GO:0051250 91 0.051
response to alcohol GO:0097305 48 0.051
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.050
cellular protein complex assembly GO:0043623 116 0.050
cellular response to biotic stimulus GO:0071216 92 0.050
stem cell proliferation GO:0072089 117 0.050
oogenesis GO:0048477 56 0.049
phagocytosis GO:0006909 66 0.049
aromatic compound catabolic process GO:0019439 286 0.049
alpha beta t cell activation GO:0046631 91 0.049
negative regulation of defense response GO:0031348 77 0.049
regulation of ossification GO:0030278 112 0.049
Human
wound healing GO:0042060 157 0.049
organelle localization GO:0051640 179 0.048
gonad development GO:0008406 141 0.048
lens development in camera type eye GO:0002088 62 0.048
heart contraction GO:0060047 93 0.048
negative regulation of bmp signaling pathway GO:0030514 35 0.048
cardiac chamber development GO:0003205 108 0.047
positive regulation of jnk cascade GO:0046330 46 0.047
myeloid leukocyte activation GO:0002274 83 0.047
mesoderm morphogenesis GO:0048332 64 0.047
negative regulation of t cell activation GO:0050868 65 0.047
regulation of map kinase activity GO:0043405 120 0.047
organophosphate catabolic process GO:0046434 232 0.047
organic hydroxy compound metabolic process GO:1901615 203 0.047
cellular response to organic cyclic compound GO:0071407 87 0.047
male sex differentiation GO:0046661 109 0.046
nucleoside triphosphate metabolic process GO:0009141 230 0.046
oocyte axis specification GO:0007309 2 0.046
purine containing compound catabolic process GO:0072523 213 0.046
regulation of b cell tolerance induction GO:0002661 2 0.046
regulation of lymphocyte differentiation GO:0045619 107 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.046
macromolecule catabolic process GO:0009057 281 0.046
chondrocyte differentiation GO:0002062 72 0.045
negative regulation of cell cycle GO:0045786 123 0.045
nucleoside catabolic process GO:0009164 206 0.045
regulation of purine nucleotide catabolic process GO:0033121 122 0.045
regulation of muscle system process GO:0090257 80 0.045
rho protein signal transduction GO:0007266 32 0.045
somite development GO:0061053 81 0.045
developmental growth involved in morphogenesis GO:0060560 138 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.045
guanosine containing compound catabolic process GO:1901069 144 0.045
regulation of peptide transport GO:0090087 91 0.044
multicellular organismal signaling GO:0035637 91 0.044
positive regulation of hydrolase activity GO:0051345 148 0.044
immune effector process GO:0002252 321 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.044
placenta development GO:0001890 140 0.044
positive regulation of secretion GO:0051047 130 0.044
Rat
oocyte development GO:0048599 33 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.044
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
segmentation GO:0035282 93 0.044
artery development GO:0060840 53 0.044
Mouse
regulation of endocytosis GO:0030100 69 0.044
muscle cell differentiation GO:0042692 261 0.044
metanephric mesenchyme morphogenesis GO:0072133 4 0.043
divalent metal ion transport GO:0070838 172 0.043
kidney mesenchyme morphogenesis GO:0072131 4 0.043
neural precursor cell proliferation GO:0061351 121 0.043
regulation of system process GO:0044057 200 0.043
Rat
blastocyst development GO:0001824 80 0.043
protein import GO:0017038 101 0.043
positive regulation of leukocyte differentiation GO:1902107 86 0.043
immune response activating signal transduction GO:0002757 116 0.042
regulation of t cell proliferation GO:0042129 92 0.042
mammary gland duct morphogenesis GO:0060603 38 0.042
regulation of intracellular protein transport GO:0033157 82 0.042
cellular lipid metabolic process GO:0044255 323 0.042
retinal ganglion cell axon guidance GO:0031290 18 0.042
stress activated protein kinase signaling cascade GO:0031098 81 0.042
regulation of binding GO:0051098 111 0.042
negative regulation of apoptotic signaling pathway GO:2001234 104 0.042
calcium ion homeostasis GO:0055074 127 0.041
embryonic limb morphogenesis GO:0030326 126 0.041
photoreceptor cell differentiation GO:0046530 52 0.041
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.041
regulation of protein targeting GO:1903533 61 0.041
response to extracellular stimulus GO:0009991 127 0.041
endocardial cushion development GO:0003197 26 0.041
bone mineralization GO:0030282 54 0.041
Human
learning or memory GO:0007611 148 0.041
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
cell fate commitment GO:0045165 210 0.041
rhythmic process GO:0048511 174 0.041
oocyte construction GO:0007308 2 0.041
actin cytoskeleton organization GO:0030036 220 0.041
dendrite development GO:0016358 115 0.041
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.041
regulation of nucleotide catabolic process GO:0030811 122 0.040
embryonic organ morphogenesis GO:0048562 276 0.040
development of primary male sexual characteristics GO:0046546 88 0.040
myotube differentiation GO:0014902 105 0.040
spermatid development GO:0007286 108 0.040
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.040
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
nucleotide catabolic process GO:0009166 217 0.040
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.039
carbohydrate derivative catabolic process GO:1901136 231 0.039
endodermal cell fate specification GO:0001714 4 0.039
nephrogenic mesenchyme development GO:0072076 3 0.039
cardiac ventricle development GO:0003231 83 0.039
ribonucleotide catabolic process GO:0009261 208 0.039
protein localization to nucleus GO:0034504 121 0.039
lung morphogenesis GO:0060425 50 0.039
gtp catabolic process GO:0006184 143 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
protein kinase b signaling GO:0043491 74 0.038
regulation of rho protein signal transduction GO:0035023 71 0.038
erk1 and erk2 cascade GO:0070371 77 0.038
synapse assembly GO:0007416 56 0.038
dendritic cell differentiation GO:0097028 26 0.037
regulation of cytoskeleton organization GO:0051493 122 0.037
cellular calcium ion homeostasis GO:0006874 119 0.037
regulation of cartilage development GO:0061035 44 0.037
cell cycle switching GO:0060184 1 0.037
cellular response to lipopolysaccharide GO:0071222 77 0.037
regulation of chondrocyte differentiation GO:0032330 33 0.036
negative regulation of cell development GO:0010721 169 0.036
regulation of cellular response to stress GO:0080135 159 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
regulation of nucleotide metabolic process GO:0006140 169 0.036
embryonic appendage morphogenesis GO:0035113 126 0.036
oxidation reduction process GO:0055114 342 0.036
regulation of stress activated mapk cascade GO:0032872 69 0.036
insemination GO:0007320 6 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.036
regulation of peptide hormone secretion GO:0090276 75 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.035
nephron development GO:0072006 109 0.035
liver development GO:0001889 66 0.035
oocyte differentiation GO:0009994 35 0.035
divalent inorganic cation transport GO:0072511 178 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
regulation of cellular response to growth factor stimulus GO:0090287 82 0.035
negative regulation of cell activation GO:0050866 111 0.035
positive regulation of t cell activation GO:0050870 101 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
regulation of extent of cell growth GO:0061387 52 0.035
negative regulation of growth GO:0045926 99 0.035
protein localization to membrane GO:0072657 108 0.034
epithelial to mesenchymal transition GO:0001837 47 0.034
anatomical structure homeostasis GO:0060249 145 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
response to nutrient levels GO:0031667 109 0.034
nephron epithelium development GO:0072009 92 0.034
regulation of canonical wnt signaling pathway GO:0060828 82 0.034
transition metal ion homeostasis GO:0055076 54 0.033
mesonephric epithelium development GO:0072163 94 0.033
i kappab kinase nf kappab signaling GO:0007249 85 0.033
b cell homeostasis GO:0001782 34 0.033
neural crest cell development GO:0014032 48 0.033
Zebrafish
regulation of ion transmembrane transport GO:0034765 119 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
activation of immune response GO:0002253 138 0.033
telencephalon development GO:0021537 186 0.033
inorganic ion transmembrane transport GO:0098660 234 0.032

Acvr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.056
disease of cellular proliferation DOID:14566 0 0.036
cancer DOID:162 0 0.033
organ system cancer DOID:0050686 0 0.033