Mus musculus

342 known processes

Adam8

a disintegrin and metallopeptidase domain 8

(Aliases: E430039A18Rik,CD156a,CD156,MS2)

Adam8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte differentiation GO:0002521 342 0.579
inflammatory response GO:0006954 244 0.537
regulation of cytokine production GO:0001817 266 0.533
defense response to other organism GO:0098542 197 0.398
immune effector process GO:0002252 321 0.384
cytokine production GO:0001816 319 0.353
myeloid leukocyte activation GO:0002274 83 0.349
adaptive immune response GO:0002250 155 0.334
Mouse
leukocyte mediated immunity GO:0002443 174 0.323
positive regulation of cell activation GO:0050867 158 0.312
negative regulation of protein metabolic process GO:0051248 282 0.311
regulation of cell activation GO:0050865 289 0.306
negative regulation of cytokine production GO:0001818 84 0.296
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.278
lymphocyte differentiation GO:0030098 242 0.271
regulation of defense response GO:0031347 233 0.266
regulation of t cell differentiation GO:0045580 83 0.240
homeostasis of number of cells GO:0048872 210 0.232
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.230
leukocyte activation involved in immune response GO:0002366 126 0.225
t cell activation involved in immune response GO:0002286 43 0.225
negative regulation of immune system process GO:0002683 209 0.222
t helper cell differentiation GO:0042093 28 0.215
response to molecule of bacterial origin GO:0002237 143 0.212
positive regulation of t cell differentiation GO:0045582 52 0.211
regulation of innate immune response GO:0045088 91 0.202
lymphocyte activation involved in immune response GO:0002285 93 0.198
myeloid cell differentiation GO:0030099 233 0.198
mapk cascade GO:0000165 281 0.194
germ cell development GO:0007281 185 0.189
cation transport GO:0006812 399 0.187
regulation of homeostatic process GO:0032844 182 0.185
regulation of cell motility GO:2000145 236 0.173
t cell proliferation GO:0042098 120 0.168
positive regulation of apoptotic process GO:0043065 217 0.167
wound healing GO:0042060 157 0.166
cytokine mediated signaling pathway GO:0019221 115 0.165
alpha beta t cell differentiation GO:0046632 69 0.162
epithelial cell proliferation GO:0050673 174 0.160
ras protein signal transduction GO:0007265 77 0.157
cell chemotaxis GO:0060326 81 0.156
cellular amino acid metabolic process GO:0006520 103 0.153
cell activation involved in immune response GO:0002263 126 0.151
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.149
cellular response to molecule of bacterial origin GO:0071219 83 0.149
reactive oxygen species metabolic process GO:0072593 84 0.146
t helper 1 type immune response GO:0042088 25 0.143
regulation of interleukin 6 production GO:0032675 55 0.142
nitrogen compound transport GO:0071705 271 0.138
t cell differentiation involved in immune response GO:0002292 30 0.137
t cell differentiation GO:0030217 174 0.137
small gtpase mediated signal transduction GO:0007264 97 0.136
regulation of apoptotic signaling pathway GO:2001233 197 0.132
regulation of vesicle mediated transport GO:0060627 139 0.131
regulation of t cell activation GO:0050863 170 0.131
myeloid leukocyte migration GO:0097529 57 0.129
leukocyte migration GO:0050900 124 0.128
divalent inorganic cation transport GO:0072511 178 0.126
gland development GO:0048732 330 0.125
transmembrane transport GO:0055085 412 0.125
amine metabolic process GO:0009308 45 0.124
response to lipopolysaccharide GO:0032496 128 0.120
t cell activation GO:0042110 289 0.120
cellular response to lipopolysaccharide GO:0071222 77 0.118
calcium mediated signaling GO:0019722 46 0.118
exocytosis GO:0006887 121 0.117
organic anion transport GO:0015711 137 0.111
regulation of secretion by cell GO:1903530 249 0.111
osteoclast differentiation GO:0030316 62 0.110
extrinsic apoptotic signaling pathway GO:0097191 126 0.110
regulation of cytokine biosynthetic process GO:0042035 59 0.110
fat cell differentiation GO:0045444 160 0.109
alpha beta t cell activation involved in immune response GO:0002287 31 0.109
skin development GO:0043588 220 0.108
positive regulation of programmed cell death GO:0043068 218 0.107
cytokine metabolic process GO:0042107 71 0.106
cellular response to lipid GO:0071396 145 0.104
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.104
Mouse
chemotaxis GO:0006935 247 0.103
apoptotic signaling pathway GO:0097190 306 0.102
immune response activating signal transduction GO:0002757 116 0.102
positive regulation of leukocyte proliferation GO:0070665 73 0.101
regulation of cellular ketone metabolic process GO:0010565 66 0.099
membrane organization GO:0061024 245 0.099
i kappab kinase nf kappab signaling GO:0007249 85 0.098
cd4 positive alpha beta t cell activation GO:0035710 45 0.098
anion transport GO:0006820 177 0.097
regulation of cellular amine metabolic process GO:0033238 20 0.097
negative regulation of cellular protein metabolic process GO:0032269 247 0.096
regulation of cell adhesion GO:0030155 154 0.096
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.095
regulation of interferon gamma production GO:0032649 57 0.095
regulation of cell migration GO:0030334 219 0.095
positive regulation of macrophage activation GO:0043032 10 0.095
neutrophil migration GO:1990266 37 0.094
regulation of leukocyte differentiation GO:1902105 159 0.094
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.094
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.094
positive regulation of cytokine production GO:0001819 174 0.093
neutrophil mediated immunity GO:0002446 19 0.093
urogenital system development GO:0001655 261 0.092
extracellular matrix organization GO:0030198 147 0.092
cytokine biosynthetic process GO:0042089 68 0.091
regulation of multi organism process GO:0043900 111 0.091
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.090
positive regulation of lymphocyte activation GO:0051251 140 0.090
cellular response to biotic stimulus GO:0071216 92 0.089
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.089
leukocyte cell cell adhesion GO:0007159 14 0.088
positive regulation of mapk cascade GO:0043410 170 0.088
cytokine secretion GO:0050663 72 0.087
second messenger mediated signaling GO:0019932 73 0.087
extracellular structure organization GO:0043062 148 0.086
regulation of protein transport GO:0051223 163 0.086
cellular response to cytokine stimulus GO:0071345 189 0.086
purine containing compound metabolic process GO:0072521 311 0.086
alpha beta t cell activation GO:0046631 91 0.086
protein catabolic process GO:0030163 221 0.086
neutrophil chemotaxis GO:0030593 36 0.085
interferon gamma production GO:0032609 67 0.085
regulation of secretion GO:0051046 274 0.084
cellular lipid metabolic process GO:0044255 323 0.084
regulation of inflammatory response GO:0050727 147 0.084
regulation of chemokine secretion GO:0090196 4 0.083
regulation of kinase activity GO:0043549 249 0.083
rho protein signal transduction GO:0007266 32 0.082
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.082
regulation of ion transport GO:0043269 215 0.082
mitotic cell cycle process GO:1903047 159 0.082
peptidyl amino acid modification GO:0018193 336 0.081
positive regulation of protein kinase activity GO:0045860 144 0.081
leukocyte chemotaxis GO:0030595 69 0.081
regulation of lymphocyte differentiation GO:0045619 107 0.081
response to growth factor GO:0070848 198 0.080
Mouse
lymphocyte proliferation GO:0046651 164 0.080
muscle cell differentiation GO:0042692 261 0.080
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.080
positive regulation of defense response GO:0031349 124 0.079
purine ribonucleotide metabolic process GO:0009150 290 0.078
regulation of leukocyte proliferation GO:0070663 121 0.078
regulation of cellular component biogenesis GO:0044087 181 0.078
positive regulation of leukocyte differentiation GO:1902107 86 0.076
eosinophil migration GO:0072677 3 0.076
regulation of map kinase activity GO:0043405 120 0.076
lipid biosynthetic process GO:0008610 179 0.076
negative regulation of cell activation GO:0050866 111 0.076
myeloid leukocyte mediated immunity GO:0002444 42 0.076
regulation of transferase activity GO:0051338 263 0.075
cellular amine metabolic process GO:0044106 44 0.075
regulation of ras protein signal transduction GO:0046578 114 0.075
placenta development GO:0001890 140 0.073
brown fat cell differentiation GO:0050873 36 0.072
positive regulation of protein modification process GO:0031401 299 0.072
regulation of establishment of protein localization GO:0070201 181 0.071
skeletal muscle organ development GO:0060538 163 0.070
peptide transport GO:0015833 133 0.070
toll like receptor signaling pathway GO:0002224 38 0.068
amide transport GO:0042886 138 0.068
compound eye development GO:0048749 1 0.068
regulation of adaptive immune response GO:0002819 90 0.067
negative regulation of intracellular signal transduction GO:1902532 167 0.067
positive regulation of t cell activation GO:0050870 101 0.067
divalent metal ion transport GO:0070838 172 0.067
positive regulation of chemokine secretion GO:0090197 4 0.066
antimicrobial peptide production GO:0002775 2 0.066
microglia development GO:0014005 2 0.066
negative regulation of apoptotic signaling pathway GO:2001234 104 0.066
positive regulation of homeostatic process GO:0032846 64 0.065
regulation of organelle organization GO:0033043 289 0.065
muscle tissue development GO:0060537 308 0.065
engulfment of apoptotic cell GO:0043652 3 0.064
multicellular organismal homeostasis GO:0048871 164 0.064
granulocyte migration GO:0097530 43 0.064
organic acid transport GO:0015849 101 0.064
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.064
macrophage activation GO:0042116 27 0.064
ion transmembrane transport GO:0034220 361 0.063
regulation of alpha beta t cell activation GO:0046634 53 0.063
protein localization to organelle GO:0033365 185 0.062
response to organonitrogen compound GO:0010243 246 0.062
cell substrate adhesion GO:0031589 130 0.062
regulation of chemokine production GO:0032642 30 0.062
nucleotide metabolic process GO:0009117 332 0.062
production of molecular mediator of immune response GO:0002440 103 0.062
chemokine production GO:0032602 34 0.061
regulation of cytokine secretion GO:0050707 61 0.061
cell adhesion GO:0007155 329 0.060
leukocyte proliferation GO:0070661 172 0.060
positive regulation of protein phosphorylation GO:0001934 242 0.060
regulation of rho protein signal transduction GO:0035023 71 0.059
positive regulation of lymphocyte proliferation GO:0050671 70 0.059
regulation of macrophage activation GO:0043030 17 0.059
inflammatory response to wounding GO:0090594 4 0.058
protein secretion GO:0009306 111 0.058
axon guidance GO:0007411 141 0.058
regulation of protein localization GO:0032880 231 0.058
regulation of lymphocyte apoptotic process GO:0070228 41 0.058
dendritic spine maintenance GO:0097062 4 0.057
calcium ion transport GO:0006816 159 0.057
immune response regulating signaling pathway GO:0002764 125 0.057
wound healing involved in inflammatory response GO:0002246 4 0.057
myeloid cell activation involved in immune response GO:0002275 34 0.057
regulation of leukocyte apoptotic process GO:2000106 56 0.057
ribonucleotide metabolic process GO:0009259 291 0.057
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.057
bone development GO:0060348 120 0.056
acute inflammatory response GO:0002526 41 0.056
g protein coupled receptor signaling pathway GO:0007186 243 0.056
defense response to virus GO:0051607 68 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
organonitrogen compound biosynthetic process GO:1901566 192 0.055
negative regulation of molecular function GO:0044092 258 0.055
axonogenesis GO:0007409 274 0.055
macromolecule catabolic process GO:0009057 281 0.054
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.054
leukocyte apoptotic process GO:0071887 71 0.054
negative regulation of cell proliferation GO:0008285 296 0.054
cellular ketone metabolic process GO:0042180 84 0.054
positive regulation of cell death GO:0010942 224 0.054
cell type specific apoptotic process GO:0097285 268 0.054
response to transforming growth factor beta GO:0071559 88 0.053
Mouse
regulation of mapk cascade GO:0043408 248 0.053
negative regulation of secretion GO:0051048 61 0.053
leukocyte homeostasis GO:0001776 79 0.053
Mouse
regulation of lymphocyte activation GO:0051249 240 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
regulation of peptide transport GO:0090087 91 0.052
positive regulation of immune effector process GO:0002699 107 0.051
positive regulation of kinase activity GO:0033674 155 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.051
negative regulation of leukocyte differentiation GO:1902106 51 0.050
ribose phosphate metabolic process GO:0019693 291 0.050
positive regulation of cellular catabolic process GO:0031331 148 0.050
nucleoside triphosphate catabolic process GO:0009143 205 0.050
regulation of lymphocyte proliferation GO:0050670 117 0.050
negative regulation of phosphorylation GO:0042326 166 0.049
antimicrobial peptide biosynthetic process GO:0002777 2 0.048
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.048
phagocytosis GO:0006909 66 0.048
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.048
defense response to bacterium GO:0042742 119 0.048
interleukin 33 mediated signaling pathway GO:0038172 1 0.048
granulocyte chemotaxis GO:0071621 39 0.048
negative regulation of synapse assembly GO:0051964 3 0.047
forebrain development GO:0030900 302 0.047
response to extracellular stimulus GO:0009991 127 0.047
chromatin modification GO:0016568 187 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.046
Mouse
mitotic cell cycle GO:0000278 195 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
interleukin 2 production GO:0032623 33 0.046
regulation of protein serine threonine kinase activity GO:0071900 157 0.046
multi multicellular organism process GO:0044706 109 0.045
regulation of t cell proliferation GO:0042129 92 0.045
peptide secretion GO:0002790 114 0.044
regulation of endocytosis GO:0030100 69 0.044
activation of immune response GO:0002253 138 0.044
negative regulation of t cell activation GO:0050868 65 0.044
smooth muscle contraction GO:0006939 44 0.044
regulation of fat cell differentiation GO:0045598 81 0.044
microglia differentiation GO:0014004 2 0.044
interleukin 18 mediated signaling pathway GO:0035655 2 0.044
negative regulation of cell migration GO:0030336 59 0.044
ribonucleoside metabolic process GO:0009119 245 0.043
regulation of protein secretion GO:0050708 82 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.043
immunoglobulin mediated immune response GO:0016064 69 0.043
positive regulation of bone resorption GO:0045780 13 0.043
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.043
organonitrogen compound catabolic process GO:1901565 264 0.043
positive regulation of cell motility GO:2000147 116 0.043
endocytosis GO:0006897 168 0.043
skeletal system development GO:0001501 356 0.042
b cell mediated immunity GO:0019724 71 0.042
response to acid chemical GO:0001101 111 0.042
female gamete generation GO:0007292 74 0.042
intracellular protein transport GO:0006886 204 0.042
negative regulation of chemokine production GO:0032682 4 0.042
response to inorganic substance GO:0010035 96 0.041
activation of innate immune response GO:0002218 56 0.041
response to oxidative stress GO:0006979 123 0.041
positive regulation of inflammatory response GO:0050729 47 0.041
regulation of osteoclast differentiation GO:0045670 36 0.041
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
cell growth GO:0016049 130 0.041
negative regulation of growth GO:0045926 99 0.040
renal system development GO:0072001 225 0.040
cell adhesion mediated by integrin GO:0033627 18 0.040
positive regulation of interleukin 6 production GO:0032755 37 0.040
regulated secretory pathway GO:0045055 32 0.040
keratinocyte migration GO:0051546 3 0.040
regulation of stress activated mapk cascade GO:0032872 69 0.040
sensory organ morphogenesis GO:0090596 242 0.039
regulation of protein kinase activity GO:0045859 232 0.039
blood vessel morphogenesis GO:0048514 285 0.038
response to organic cyclic compound GO:0014070 198 0.038
Mouse
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.038
regulation of binding GO:0051098 111 0.038
cellular response to organonitrogen compound GO:0071417 145 0.038
regulation of mast cell activation GO:0033003 21 0.038
establishment of protein localization to organelle GO:0072594 118 0.038
glial cell differentiation GO:0010001 131 0.038
Mouse
cellular homeostasis GO:0019725 240 0.038
positive regulation of nucleotide metabolic process GO:0045981 114 0.038
positive regulation of protein transport GO:0051222 93 0.038
gastrulation GO:0007369 116 0.038
glycosyl compound catabolic process GO:1901658 206 0.037
nucleoside metabolic process GO:0009116 246 0.037
regulation of myeloid leukocyte differentiation GO:0002761 58 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.037
nuclear transport GO:0051169 139 0.037
ossification GO:0001503 216 0.037
nucleoside catabolic process GO:0009164 206 0.037
inner ear morphogenesis GO:0042472 101 0.037
negative regulation of secretion by cell GO:1903531 54 0.037
positive regulation of interferon gamma production GO:0032729 39 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
nucleotide catabolic process GO:0009166 217 0.036
positive regulation of intracellular transport GO:0032388 70 0.036
positive regulation of chemokine production GO:0032722 22 0.036
regulation of thymocyte migration GO:2000410 2 0.036
oogenesis GO:0048477 56 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
positive regulation of organelle organization GO:0010638 128 0.035
cation homeostasis GO:0055080 212 0.035
skeletal system morphogenesis GO:0048705 203 0.035
regulation of exocytosis GO:0017157 61 0.035
stress activated protein kinase signaling cascade GO:0031098 81 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.035
interspecies interaction between organisms GO:0044419 83 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
positive regulation of monocyte chemotaxis GO:0090026 2 0.034
positive regulation of rho gtpase activity GO:0032321 41 0.034
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.034
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.034
regulation of intracellular transport GO:0032386 159 0.034
lymphocyte homeostasis GO:0002260 64 0.034
regulation of cell cycle GO:0051726 281 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
learning or memory GO:0007611 148 0.034
Mouse
carboxylic acid transport GO:0046942 100 0.034
positive regulation of leukocyte apoptotic process GO:2000108 21 0.033
positive regulation of cell migration GO:0030335 109 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.033
antigen receptor mediated signaling pathway GO:0050851 64 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.033
t cell mediated immunity GO:0002456 50 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
stem cell differentiation GO:0048863 268 0.033
Mouse
response to peptide GO:1901652 136 0.033
regulation of body fluid levels GO:0050878 162 0.032
regulation of protein processing GO:0070613 96 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
striated muscle cell development GO:0055002 125 0.032
regulation of cellular response to stress GO:0080135 159 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
response to metal ion GO:0010038 47 0.031
muscle contraction GO:0006936 101 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
positive regulation of secretion GO:0051047 130 0.031
spermatogenesis GO:0007283 284 0.031
cognition GO:0050890 149 0.031
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.030
negative regulation of t helper 1 type immune response GO:0002826 5 0.030
sequestering of metal ion GO:0051238 19 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.030
striated muscle tissue development GO:0014706 293 0.030
pattern recognition receptor signaling pathway GO:0002221 47 0.030
nuclear division GO:0000280 158 0.030
actin cytoskeleton organization GO:0030036 220 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
protein ubiquitination GO:0016567 171 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
interleukin 6 production GO:0032635 58 0.029
odontogenesis of dentin containing tooth GO:0042475 66 0.029
neutrophil mediated killing of fungus GO:0070947 3 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
cellular response to acid chemical GO:0071229 68 0.029
leukocyte degranulation GO:0043299 27 0.029
regulation of leukocyte mediated immunity GO:0002703 104 0.029
superoxide metabolic process GO:0006801 27 0.028
chromatin organization GO:0006325 206 0.028
sequestering of calcium ion GO:0051208 18 0.028
regulation of cell cycle process GO:0010564 160 0.028
t helper 1 cell differentiation GO:0045063 13 0.028
cytoplasmic transport GO:0016482 234 0.028
protein targeting GO:0006605 143 0.028
negative regulation of lymphocyte activation GO:0051250 91 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
leukocyte aggregation GO:0070486 1 0.028
myeloid cell homeostasis GO:0002262 114 0.027
Mouse
digestive system development GO:0055123 200 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
innate immune response activating signal transduction GO:0002758 50 0.027
angiogenesis GO:0001525 201 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
protein import GO:0017038 101 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
maintenance of location GO:0051235 89 0.027
small molecule biosynthetic process GO:0044283 132 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
synaptic transmission GO:0007268 329 0.027
regulation of protein catabolic process GO:0042176 108 0.027
regulation of mast cell degranulation GO:0043304 16 0.027
purine nucleoside catabolic process GO:0006152 205 0.027
ribonucleotide catabolic process GO:0009261 208 0.026
cerebral cortex cell migration GO:0021795 44 0.026
negative regulation of cytokine biosynthetic process GO:0042036 13 0.026
myotube differentiation GO:0014902 105 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
macromolecule methylation GO:0043414 120 0.026
lymphocyte mediated immunity GO:0002449 139 0.026
regulation of nucleocytoplasmic transport GO:0046822 73 0.026
organic acid biosynthetic process GO:0016053 86 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.026
sensory perception GO:0007600 245 0.026
bone morphogenesis GO:0060349 78 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.026
Mouse
purine containing compound catabolic process GO:0072523 213 0.026
dendrite development GO:0016358 115 0.026
detection of stimulus GO:0051606 84 0.026
methylation GO:0032259 134 0.026
cellular chemical homeostasis GO:0055082 215 0.026
regulation of calcium ion transport GO:0051924 69 0.026
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.026
actin filament organization GO:0007015 113 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.025
neuron death GO:0070997 154 0.025
interleukin 12 secretion GO:0072610 3 0.025
epidermis development GO:0008544 187 0.025
t cell extravasation GO:0072683 4 0.025
positive regulation of cytokine biosynthetic process GO:0042108 40 0.025
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
regulation of toll like receptor signaling pathway GO:0034121 20 0.025
jnk cascade GO:0007254 72 0.025
connective tissue development GO:0061448 179 0.025
positive regulation of innate immune response GO:0045089 80 0.025
regulation of hydrolase activity GO:0051336 246 0.025
regulation of tissue remodeling GO:0034103 38 0.025
nuclear import GO:0051170 95 0.025
peptide metabolic process GO:0006518 46 0.025
regulation of myeloid cell differentiation GO:0045637 96 0.025
acute phase response GO:0006953 10 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.025
kidney development GO:0001822 213 0.025
icosanoid metabolic process GO:0006690 33 0.025
disruption by host of symbiont cells GO:0051852 11 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
regulation of anatomical structure size GO:0090066 178 0.024
regulation of response to wounding GO:1903034 189 0.024
blood circulation GO:0008015 195 0.024
leukocyte migration involved in inflammatory response GO:0002523 7 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
cell matrix adhesion GO:0007160 68 0.024
dendritic cell differentiation GO:0097028 26 0.024
positive regulation of cell cycle GO:0045787 92 0.024
circulatory system process GO:0003013 197 0.024
regulation of hormone levels GO:0010817 211 0.024
regulation of t helper 1 type immune response GO:0002825 17 0.024
t cell differentiation in thymus GO:0033077 77 0.024
carbohydrate metabolic process GO:0005975 230 0.023
regulation of tumor necrosis factor production GO:0032680 49 0.023
lymphocyte apoptotic process GO:0070227 54 0.023
negative regulation of protein modification process GO:0031400 163 0.023
thymocyte migration GO:0072679 2 0.023
positive regulation of t cell proliferation GO:0042102 52 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
digestive tract morphogenesis GO:0048546 147 0.023
lipid localization GO:0010876 126 0.023
bone trabecula morphogenesis GO:0061430 12 0.023
protein localization to nucleus GO:0034504 121 0.023
positive regulation of osteoclast differentiation GO:0045672 15 0.023
insulin receptor signaling pathway GO:0008286 49 0.023
gliogenesis GO:0042063 141 0.023
Mouse
cell cycle g1 s phase transition GO:0044843 57 0.023
positive regulation of macrophage chemotaxis GO:0010759 5 0.023
l amino acid transport GO:0015807 32 0.023
tissue remodeling GO:0048771 102 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
regulation of response to cytokine stimulus GO:0060759 23 0.023

Adam8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.034
disease of anatomical entity DOID:7 0 0.034
immune system disease DOID:2914 0 0.025
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023