|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.725
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.636
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.620
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.617
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.615
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.599
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.593
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.555
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.540
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.528
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.522
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.497
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.456
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.454
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.448
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.424
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.395
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.389
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.384
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.373
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.373
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.366
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.358
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.347
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.346
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.344
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.343
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.339
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.334
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.334
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.331
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.330
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.323
|
|
|
|
establishment of melanosome localization
|
GO:0032401 |
11 |
0.321
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.320
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.320
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.317
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.315
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.309
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.305
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.304
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.296
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.293
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.292
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.289
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.287
|
Human Worm Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.285
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.284
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.283
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.279
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.273
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.260
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.260
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.256
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.253
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.253
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.251
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.250
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.246
|
Fly |
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.244
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.242
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.241
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.240
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.238
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.237
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.237
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.236
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.235
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.228
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.228
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.216
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.215
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.212
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.212
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.210
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.209
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.209
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.206
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.205
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.205
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.204
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.201
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.200
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.198
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.197
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.194
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.194
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.193
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.193
|
Human Worm |
|
|
regulation of protein targeting to membrane
|
GO:0090313 |
9 |
0.192
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.189
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.187
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.186
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.186
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.186
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.186
|
Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.181
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.175
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.169
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.167
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.167
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.167
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.166
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.164
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.163
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.161
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.160
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.160
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.160
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.159
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.159
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.158
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.158
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.157
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.156
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.156
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.155
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.155
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.155
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.153
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.153
|
Human |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.149
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.148
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.146
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.146
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.145
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.145
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.144
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.143
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.142
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.141
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.139
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.139
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.138
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.138
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.136
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.136
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.135
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.135
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.134
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.133
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.132
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.132
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.132
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.131
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.131
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.130
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.130
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.128
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.128
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.127
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.127
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.127
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.126
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.126
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.126
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.125
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.125
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.125
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.124
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.123
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.121
|
Human |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.119
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.118
|
Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.117
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.114
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.112
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.111
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.111
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.110
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.110
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.109
|
|
|
|
melanosome localization
|
GO:0032400 |
12 |
0.109
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.109
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.109
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.108
|
Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.108
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.107
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.107
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.106
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.105
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.105
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.104
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.104
|
|
|
|
cellular response to salt stress
|
GO:0071472 |
1 |
0.103
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.102
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.102
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.102
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.101
|
Fly |
|
|
schwann cell differentiation
|
GO:0014037 |
26 |
0.101
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.100
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.100
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.100
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.100
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.100
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.099
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.099
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.099
|
|
|
|
melanosome transport
|
GO:0032402 |
11 |
0.099
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.099
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.098
|
|
|
|
regulation of ral gtpase activity
|
GO:0032315 |
4 |
0.097
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.096
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.096
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.095
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.095
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.094
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.094
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.094
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.093
|
Fly |
|
|
glucose transport
|
GO:0015758 |
56 |
0.093
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.092
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.092
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.090
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.090
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.090
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.089
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.088
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.088
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.088
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.088
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.088
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.087
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.087
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.086
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.086
|
|
|
|
pigment granule localization
|
GO:0051875 |
13 |
0.085
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.085
|
|
|
|
schwann cell development
|
GO:0014044 |
22 |
0.085
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.084
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.084
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.084
|
Human Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.083
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.083
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.083
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.083
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.082
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.082
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.082
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.082
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.081
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.080
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.080
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.080
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.080
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.080
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.080
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.079
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.079
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.078
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.078
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.078
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.078
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.078
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.078
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.078
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.078
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.077
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.077
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.077
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.076
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.076
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.075
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.075
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.074
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.073
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.073
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.073
|
Human Worm |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.073
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.073
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.073
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.072
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.072
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.071
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.071
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.071
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.071
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.071
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.069
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.069
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.068
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.068
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.067
|
|
|
|
protein localization to synapse
|
GO:0035418 |
11 |
0.067
|
Worm |
|
|
dna alkylation
|
GO:0006305 |
43 |
0.067
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.067
|
|
|
|
memory
|
GO:0007613 |
58 |
0.067
|
Worm |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.067
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.067
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.067
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.066
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.066
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.065
|
|
|
|
regulation of polyamine transmembrane transport
|
GO:1902267 |
5 |
0.065
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.065
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.064
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.063
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.062
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.062
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.062
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.062
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.062
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.062
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.062
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.061
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.061
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.061
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.059
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.059
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.059
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.058
|
Worm |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.058
|
|
|
|
regulation of ral protein signal transduction
|
GO:0032485 |
4 |
0.057
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.057
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.057
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.057
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.057
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.057
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.057
|
Human |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.057
|
Fly |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.057
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.057
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.056
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.056
|
Human |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.056
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.056
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.056
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.056
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.056
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.056
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.055
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.055
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.055
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.055
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.054
|
Human Worm |
|
|
anion transport
|
GO:0006820 |
177 |
0.054
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.054
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.054
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.054
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.054
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.054
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.054
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.053
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.053
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.053
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.053
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.052
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.052
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.052
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.052
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.052
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.052
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.052
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.052
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.051
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.051
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.051
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.051
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.051
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.051
|
|
|
|
pigment granule transport
|
GO:0051904 |
12 |
0.051
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.050
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.050
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.050
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.049
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.049
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.049
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.048
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.048
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.048
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.048
|
|
|
|
positive regulation of interleukin 5 secretion
|
GO:2000664 |
1 |
0.048
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.048
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.047
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.047
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.047
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.047
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.046
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.046
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.046
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.046
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
37 |
0.046
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.046
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.045
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.045
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.045
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.045
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.045
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.045
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.045
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.044
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.044
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.044
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.044
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.044
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.044
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.044
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.044
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.043
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.043
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.043
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.043
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.043
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.043
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.042
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.042
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.042
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.042
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.042
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.042
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.042
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.041
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.041
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.041
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.041
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.041
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.041
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.041
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
20 |
0.041
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.040
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.040
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.040
|
|
|
|
negative regulation of stress fiber assembly
|
GO:0051497 |
4 |
0.040
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.040
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.040
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.039
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.039
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.039
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.039
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.039
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.039
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.039
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.039
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.039
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.039
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.038
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.038
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.038
|
Fly |
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.038
|
|
|
|
negative regulation of transposition
|
GO:0010529 |
2 |
0.038
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.038
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.038
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.038
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.037
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.037
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.037
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.037
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.037
|
|
|
|
positive regulation of oocyte development
|
GO:0060282 |
4 |
0.037
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.037
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.037
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.037
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.036
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.036
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.036
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.036
|
|
|
|
positive regulation of t helper 2 cell activation
|
GO:2000570 |
2 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.036
|
Fly |
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.036
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.036
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.036
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.036
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.036
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.036
|
|
|
|
cellular response to parathyroid hormone stimulus
|
GO:0071374 |
2 |
0.036
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.035
|
|
|
|
t helper 2 cell activation
|
GO:0035712 |
2 |
0.035
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.035
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.035
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.035
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.035
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.035
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.035
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.035
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.035
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.034
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.034
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.034
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.034
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.034
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.033
|
|
|
|
protein deubiquitination
|
GO:0016579 |
19 |
0.033
|
|
|
|
dna methylation on cytosine
|
GO:0032776 |
5 |
0.033
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.033
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.033
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.033
|
|
|
|
protein dna complex disassembly
|
GO:0032986 |
1 |
0.033
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.033
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.033
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.033
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.033
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.032
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.032
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.032
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.032
|
|
