Mus musculus

167 known processes

Adora3

adenosine A3 receptor

(Aliases: ARA3,4930578J19Rik,A3AR,A3R,AA3R,MGC118217,Gpcr2,1700001D09Rik)

Adora3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hypotonic response GO:0006971 3 0.823
detection of chemical stimulus involved in sensory perception of pain GO:0050968 3 0.669
reactive nitrogen species metabolic process GO:2001057 0 0.277
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.268
ion transmembrane transport GO:0034220 361 0.247
cellular hypotonic response GO:0071476 3 0.170
urinary bladder smooth muscle contraction GO:0014832 5 0.158
reactive oxygen species biosynthetic process GO:1903409 8 0.140
cellular response to osmotic stress GO:0071470 7 0.134
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.133
muscle system process GO:0003012 141 0.130
Mouse
inflammatory response GO:0006954 244 0.129
microglial cell activation GO:0001774 3 0.123
osmosensory signaling pathway GO:0007231 1 0.105
skin development GO:0043588 220 0.102
regulation of hormone levels GO:0010817 211 0.100
positive regulation of secretion GO:0051047 130 0.098
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.097
transmembrane transport GO:0055085 412 0.096
cellular homeostasis GO:0019725 240 0.094
myeloid cell differentiation GO:0030099 233 0.092
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.090
hyperosmotic salinity response GO:0042538 1 0.089
urinary tract smooth muscle contraction GO:0014848 6 0.089
reactive oxygen species metabolic process GO:0072593 84 0.088
cytosolic calcium ion homeostasis GO:0051480 70 0.086
regulation of reactive oxygen species metabolic process GO:2000377 40 0.085
striated muscle contraction GO:0006941 45 0.082
regulation of response to osmotic stress GO:0047484 3 0.079
cell cell junction organization GO:0045216 72 0.079
peptide secretion GO:0002790 114 0.077
nitrogen compound transport GO:0071705 271 0.077
hormone secretion GO:0046879 128 0.074
positive regulation of apoptotic process GO:0043065 217 0.074
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.072
muscle contraction GO:0006936 101 0.071
Mouse
cation transmembrane transport GO:0098655 266 0.071
anatomical structure maturation GO:0071695 49 0.070
epidermis development GO:0008544 187 0.069
cellular ion homeostasis GO:0006873 165 0.068
macrophage activation GO:0042116 27 0.065
regulation of secretion GO:0051046 274 0.065
enucleate erythrocyte differentiation GO:0043353 8 0.064
regulation of ion transmembrane transport GO:0034765 119 0.063
homeostasis of number of cells GO:0048872 210 0.062
divalent inorganic cation homeostasis GO:0072507 138 0.062
cellular response to organic cyclic compound GO:0071407 87 0.061
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.061
cellular chemical homeostasis GO:0055082 215 0.060
positive regulation of calcium ion transport GO:0051928 27 0.060
organic acid transport GO:0015849 101 0.060
hair cycle phase GO:0044851 16 0.058
positive regulation of cell projection organization GO:0031346 95 0.058
amide transport GO:0042886 138 0.056
positive regulation of cell development GO:0010720 237 0.056
regulation of cell size GO:0008361 72 0.055
protein oligomerization GO:0051259 67 0.055
amino acid transport GO:0006865 61 0.055
regulation of transmembrane transport GO:0034762 128 0.055
vasopressin secretion GO:0030103 1 0.054
response to osmotic stress GO:0006970 21 0.054
cellular response to organonitrogen compound GO:0071417 145 0.053
Mouse
positive regulation of nervous system development GO:0051962 221 0.053
regulation of neuron projection development GO:0010975 169 0.052
axonogenesis GO:0007409 274 0.051
cellular response to cytokine stimulus GO:0071345 189 0.051
smooth muscle contraction involved in micturition GO:0060083 3 0.050
cellular metal ion homeostasis GO:0006875 151 0.050
metal ion homeostasis GO:0055065 189 0.049
sensory perception GO:0007600 245 0.049
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.049
response to organophosphorus GO:0046683 22 0.049
cellular response to abiotic stimulus GO:0071214 56 0.049
response to peptide hormone GO:0043434 127 0.048
regulation of neuron differentiation GO:0045664 281 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
positive regulation of neuron projection development GO:0010976 79 0.044
regulation of axon extension GO:0030516 43 0.043
molting cycle GO:0042303 90 0.042
negative regulation of cell proliferation GO:0008285 296 0.042
neuron projection extension GO:1990138 64 0.042
cellular calcium ion homeostasis GO:0006874 119 0.041
establishment of blood brain barrier GO:0060856 8 0.041
calcium ion transport GO:0006816 159 0.040
regulation of metal ion transport GO:0010959 106 0.040
response to hypoxia GO:0001666 58 0.040
developmental cell growth GO:0048588 84 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.039
fat cell differentiation GO:0045444 160 0.039
detection of stimulus involved in sensory perception GO:0050906 44 0.039
developmental maturation GO:0021700 193 0.039
response to nutrient levels GO:0031667 109 0.038
multicellular organismal homeostasis GO:0048871 164 0.038
digestive system development GO:0055123 200 0.037
anion transport GO:0006820 177 0.037
response to decreased oxygen levels GO:0036293 59 0.037
diet induced thermogenesis GO:0002024 7 0.036
acute phase response GO:0006953 10 0.036
response to nerve growth factor GO:1990089 3 0.035
cell junction assembly GO:0034329 52 0.035
positive regulation of axon extension GO:0045773 20 0.035
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.035
cellular response to nerve growth factor stimulus GO:1990090 3 0.035
regulation of ion transport GO:0043269 215 0.035
Mouse
cell growth GO:0016049 130 0.034
negative regulation of cell development GO:0010721 169 0.034
multicellular organismal response to stress GO:0033555 62 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
digestive tract development GO:0048565 190 0.034
response to ph GO:0009268 14 0.033
response to growth factor GO:0070848 198 0.032
renal system process GO:0003014 48 0.032
Mouse
blood vessel morphogenesis GO:0048514 285 0.032
developmental growth involved in morphogenesis GO:0060560 138 0.032
organic cyclic compound catabolic process GO:1901361 295 0.031
immune effector process GO:0002252 321 0.031
cell cell junction assembly GO:0007043 27 0.030
cellular amine metabolic process GO:0044106 44 0.029
regulation of calcium ion transport GO:0051924 69 0.029
dicarboxylic acid transport GO:0006835 29 0.028
response to atp GO:0033198 8 0.028
response to pain GO:0048265 26 0.028
response to reactive oxygen species GO:0000302 56 0.028
hyperosmotic response GO:0006972 4 0.027
positive regulation of ion transmembrane transport GO:0034767 24 0.027
cell junction organization GO:0034330 77 0.027
amine metabolic process GO:0009308 45 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
response to oxidative stress GO:0006979 123 0.027
response to temperature stimulus GO:0009266 55 0.027
positive regulation of ion transport GO:0043270 65 0.026
ras protein signal transduction GO:0007265 77 0.026
biological phase GO:0044848 20 0.026
heterocycle catabolic process GO:0046700 280 0.025
organic anion transport GO:0015711 137 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
Mouse
myeloid cell homeostasis GO:0002262 114 0.024
carboxylic acid transport GO:0046942 100 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
Mouse
purine containing compound metabolic process GO:0072521 311 0.024
Mouse
peptide hormone secretion GO:0030072 109 0.024
nucleotide metabolic process GO:0009117 332 0.024
Mouse
male gamete generation GO:0048232 285 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
cation transport GO:0006812 399 0.023
erythrocyte differentiation GO:0030218 88 0.023
aromatic compound catabolic process GO:0019439 286 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
response to purine containing compound GO:0014074 28 0.023
cellular ketone metabolic process GO:0042180 84 0.022
regulation of digestive system process GO:0044058 13 0.022
peptide transport GO:0015833 133 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
regulation of response to wounding GO:1903034 189 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
organophosphate catabolic process GO:0046434 232 0.020
regulation of cell projection organization GO:0031344 206 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
Mouse
regulation of anatomical structure size GO:0090066 178 0.020
Mouse
spermatogenesis GO:0007283 284 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
positive regulation of growth GO:0045927 104 0.019
detection of chemical stimulus GO:0009593 16 0.019
Mouse
protein maturation GO:0051604 176 0.019
positive regulation of digestive system process GO:0060456 2 0.018
regulation of cell activation GO:0050865 289 0.018
sensory perception of temperature stimulus GO:0050951 9 0.018
glutamate secretion GO:0014047 8 0.018
temperature homeostasis GO:0001659 26 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.018
nucleoside catabolic process GO:0009164 206 0.017
membrane organization GO:0061024 245 0.017
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of nitric oxide biosynthetic process GO:0045428 18 0.017
regulation of proteolysis GO:0030162 164 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
macromolecule catabolic process GO:0009057 281 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
t cell activation GO:0042110 289 0.017
Mouse
germ cell development GO:0007281 185 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
brown fat cell differentiation GO:0050873 36 0.017
regulation of cellular catabolic process GO:0031329 242 0.016
divalent metal ion transport GO:0070838 172 0.016
muscle tissue development GO:0060537 308 0.016
regulation of gastric acid secretion GO:0060453 2 0.016
rho protein signal transduction GO:0007266 32 0.016
protein ubiquitination GO:0016567 171 0.016
protein modification by small protein conjugation GO:0032446 187 0.015
peptidyl amino acid modification GO:0018193 336 0.015
cellular protein complex assembly GO:0043623 116 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
negative regulation of immune system process GO:0002683 209 0.015
Mouse
multicellular organismal metabolic process GO:0044236 28 0.015
regulation of cell growth GO:0001558 91 0.015
response to alkaloid GO:0043279 34 0.015
muscle cell differentiation GO:0042692 261 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
Mouse
response to organic cyclic compound GO:0014070 198 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
micturition GO:0060073 6 0.015
response to inorganic substance GO:0010035 96 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
regulation of protein localization GO:0032880 231 0.015
Mouse
microtubule based process GO:0007017 236 0.014
response to dietary excess GO:0002021 18 0.014
regulation of secretion by cell GO:1903530 249 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
divalent inorganic cation transport GO:0072511 178 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cellular response to lipid GO:0071396 145 0.014
Mouse
actin cytoskeleton organization GO:0030036 220 0.014
regulation of inflammatory response GO:0050727 147 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
Mouse
cell adhesion GO:0007155 329 0.013
regulation of cell cycle GO:0051726 281 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
leukocyte mediated immunity GO:0002443 174 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
Mouse
response to organonitrogen compound GO:0010243 246 0.013
Mouse
glycoprotein metabolic process GO:0009100 116 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
Mouse
protein processing GO:0016485 163 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
carbohydrate metabolic process GO:0005975 230 0.013
response to hydrogen peroxide GO:0042542 32 0.013
organelle assembly GO:0070925 177 0.013
cellular protein catabolic process GO:0044257 155 0.013
apoptotic signaling pathway GO:0097190 306 0.013
Mouse
calcium ion transmembrane transport GO:0070588 85 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
response to extracellular stimulus GO:0009991 127 0.012
Mouse
lymphocyte proliferation GO:0046651 164 0.012
chromatin organization GO:0006325 206 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
carbohydrate homeostasis GO:0033500 128 0.012
methylation GO:0032259 134 0.012
regulation of calcium ion import GO:0090279 10 0.012
response to tumor necrosis factor GO:0034612 26 0.012
compound eye development GO:0048749 1 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
striated muscle tissue development GO:0014706 293 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
Mouse
glycerophospholipid metabolic process GO:0006650 71 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
cation homeostasis GO:0055080 212 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
Mouse
oxidation reduction process GO:0055114 342 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of defense response GO:0031347 233 0.012
chemotaxis GO:0006935 247 0.012
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
Mouse
gtp metabolic process GO:0046039 144 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
glycerolipid metabolic process GO:0046486 122 0.011
protein catabolic process GO:0030163 221 0.011
lateral inhibition GO:0046331 1 0.011
sequestering of calcium ion GO:0051208 18 0.011
ossification GO:0001503 216 0.011
regulation of organelle organization GO:0033043 289 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
Mouse
endocytosis GO:0006897 168 0.011
Mouse
sensory perception of pain GO:0019233 47 0.011
Mouse
dna metabolic process GO:0006259 303 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
skeletal system development GO:0001501 356 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
hair follicle development GO:0001942 85 0.011
organelle localization GO:0051640 179 0.011
mapk cascade GO:0000165 281 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
Mouse
leukocyte differentiation GO:0002521 342 0.011
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
gastric acid secretion GO:0001696 6 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
synaptic transmission GO:0007268 329 0.011
Mouse
negative regulation of cell activation GO:0050866 111 0.011
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.010
histone modification GO:0016570 159 0.010
sequestering of metal ion GO:0051238 19 0.010
oocyte construction GO:0007308 2 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
regulation of mapk cascade GO:0043408 248 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
regulation of membrane potential GO:0042391 192 0.010
Mouse
positive regulation of cell death GO:0010942 224 0.010
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
Mouse
protein tetramerization GO:0051262 23 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
phospholipid metabolic process GO:0006644 87 0.010
organelle fission GO:0048285 170 0.010
activation of immune response GO:0002253 138 0.010

Adora3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.011
inherited metabolic disorder DOID:655 0 0.011
immune system disease DOID:2914 0 0.010