|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.742
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.740
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.695
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.655
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.554
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.534
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.511
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.485
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.484
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.439
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.427
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.418
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.398
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.385
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.366
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.297
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.287
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.266
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.257
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.243
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.243
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.240
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.240
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.240
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.236
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.234
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.225
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.224
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.217
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.214
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.212
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.204
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.204
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.199
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.187
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.186
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.179
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.176
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.176
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.173
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.172
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.171
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.171
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.169
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.165
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.158
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.156
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.155
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.154
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.154
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.153
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.153
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.147
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.147
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.145
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.145
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.145
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.139
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.139
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.138
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.137
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.135
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.134
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.129
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.129
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.129
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.123
|
Fly |
|
|
synapse organization
|
GO:0050808 |
125 |
0.123
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.121
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.119
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.119
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.118
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.117
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.117
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.112
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.111
|
Fly |
|
|
cartilage development
|
GO:0051216 |
140 |
0.109
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.108
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.108
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.107
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.107
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.106
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.106
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.103
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.103
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.103
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.101
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.100
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.100
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.097
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.097
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.096
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.095
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.094
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.094
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.093
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.093
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.092
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.092
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.092
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.092
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.091
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.090
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.090
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.090
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.090
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.089
|
|
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.088
|
|
|
|
memory
|
GO:0007613 |
58 |
0.087
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.086
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.086
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.086
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.085
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.085
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.084
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.083
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.083
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.083
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.083
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.082
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.082
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.082
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.081
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.081
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.079
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.078
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.078
|
Fly |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.077
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.077
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.076
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.076
|
Fly |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.074
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.074
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.074
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.074
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.073
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.072
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.071
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.071
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.071
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.071
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.071
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.070
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.070
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.069
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.069
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.068
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.068
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.068
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.068
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.068
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.067
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.066
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.066
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.066
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.065
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.065
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.065
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.064
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.063
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.063
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.063
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.063
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.062
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.062
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.062
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.061
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.061
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.061
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.061
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.060
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.060
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.059
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.059
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.059
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.059
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.059
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.059
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.059
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.058
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.058
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.058
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.057
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.057
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.056
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.055
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.055
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.055
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.055
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.055
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.054
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.054
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.054
|
Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.054
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.054
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.054
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.053
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.053
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.053
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.053
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.053
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.052
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.052
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.052
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.052
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.052
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.052
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.051
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.051
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.051
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.051
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.051
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.051
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.051
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.051
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.051
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.051
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.050
|
Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.050
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.050
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.049
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.049
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.049
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.049
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.049
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.049
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.049
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.048
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.048
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.048
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.048
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.048
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.048
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.048
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.047
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.047
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.047
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.047
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.046
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.046
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.046
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.046
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.046
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.046
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.046
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.046
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.046
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.046
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.046
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.046
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.046
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.045
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.045
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.045
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.045
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.045
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
7 |
0.045
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.045
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.044
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.044
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.044
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.043
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.043
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.042
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.042
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.042
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.042
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.042
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.042
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.042
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.041
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
42 |
0.041
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.041
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.041
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.041
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.041
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.040
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.040
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.040
|
|
|
|
negative regulation of fatty acid oxidation
|
GO:0046322 |
5 |
0.040
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.040
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.040
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.040
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.040
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.039
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.039
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.039
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.039
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.039
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.038
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.038
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.038
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.038
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.038
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.038
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.038
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.038
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.038
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.038
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.038
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.037
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.037
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.037
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.037
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.037
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.037
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.036
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.036
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.036
|
|
|
|
histone deubiquitination
|
GO:0016578 |
2 |
0.036
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.036
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.036
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.036
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.036
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.036
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.036
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.036
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.035
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.035
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.035
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.035
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.035
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.035
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.035
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.035
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.035
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.034
|
|
|
|
protein homotrimerization
|
GO:0070207 |
4 |
0.034
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.034
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.034
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.034
|
|
|
|
visual perception
|
GO:0007601 |
52 |
0.034
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
44 |
0.034
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.034
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.034
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.034
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.034
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.034
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.034
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.034
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.033
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.033
|
|
|
|
positive regulation of interleukin 5 secretion
|
GO:2000664 |
1 |
0.033
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.033
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.033
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.033
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.033
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.032
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.032
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.032
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.032
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.032
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.032
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.032
|
Mouse |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.031
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.030
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.030
|
|
|
|
camera type eye photoreceptor cell differentiation
|
GO:0060219 |
15 |
0.030
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.030
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.030
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.030
|
|
|
|
planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:0061348 |
2 |
0.030
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.030
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.030
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.030
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.030
|
Fly |
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.030
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.030
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.030
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.030
|
|
|
|
plasma membrane long chain fatty acid transport
|
GO:0015911 |
1 |
0.030
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.029
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.029
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.029
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.029
|
Fly |
|
|
fertilization
|
GO:0009566 |
127 |
0.029
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.029
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.029
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.029
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.029
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.029
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.029
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.029
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.029
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.029
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.028
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.028
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.028
|
|
|
|
regulation of ral protein signal transduction
|
GO:0032485 |
4 |
0.028
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.028
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.028
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.028
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.028
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.028
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.028
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.027
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.027
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.027
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.027
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.027
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.027
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.027
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
33 |
0.026
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
44 |
0.026
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.026
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.026
|
|
|
|
regulation of phospholipid biosynthetic process
|
GO:0071071 |
3 |
0.026
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.026
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.026
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.026
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.026
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.026
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.026
|
|
|
|
negative regulation of fatty acid transport
|
GO:2000192 |
1 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.026
|
|
|
|
regulation of ral gtpase activity
|
GO:0032315 |
4 |
0.025
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.025
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.025
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.025
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.025
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.025
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.025
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.025
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.025
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.025
|
|
|
|
negative regulation of sterol transport
|
GO:0032372 |
4 |
0.025
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.025
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.025
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.025
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.025
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.025
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.025
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.024
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.024
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.024
|
Fly |
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.024
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.024
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.024
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.024
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.024
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.024
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.024
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.024
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.024
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.024
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.023
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.023
|
|
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.023
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
39 |
0.023
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.023
|
|
|
|
glycogen cell differentiation involved in embryonic placenta development
|
GO:0060709 |
1 |
0.023
|
|
|
|
mating
|
GO:0007618 |
27 |
0.023
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.023
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.023
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.023
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.023
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.023
|
|
|
|
chromatin remodeling
|
GO:0006338 |
32 |
0.023
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.023
|
|
|
|
t helper 2 cell activation
|
GO:0035712 |
2 |
0.022
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.022
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.022
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.022
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.022
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.022
|
|
|
|
negative regulation of translational initiation
|
GO:0045947 |
4 |
0.022
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.022
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.022
|
|
|
|
response to denervation involved in regulation of muscle adaptation
|
GO:0014894 |
4 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.022
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.022
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.022
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.022
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.022
|
|
|
|
protein transmembrane transport
|
GO:0071806 |
8 |
0.022
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.021
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.021
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.021
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.021
|
Fly |
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.021
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.021
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.021
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
29 |
0.021
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.021
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.021
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.021
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.021
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.021
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.021
|
|
