Mus musculus

357 known processes

Agt

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

(Aliases: Serpina8,Aogen,AI265500,AngI,AngII)

Agt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
renin angiotensin regulation of aldosterone production GO:0002018 3 0.999
regulation of renal output by angiotensin GO:0002019 2 0.999
positive regulation of blood pressure GO:0045777 21 0.981
superoxide metabolic process GO:0006801 27 0.972
Rat
cholesterol esterification GO:0034435 3 0.970
Human
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.966
activation of janus kinase activity GO:0042976 2 0.966
Human
drinking behavior GO:0042756 5 0.963
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.944
regulation of systemic arterial blood pressure GO:0003073 61 0.934
sterol esterification GO:0034434 3 0.924
Human
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.921
regulation of cholesterol esterification GO:0010872 2 0.914
Human
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.896
positive regulation of cholesterol esterification GO:0010873 1 0.896
Human
cellular lipid metabolic process GO:0044255 323 0.877
regulation of phospholipase a2 activity GO:0032429 3 0.861
regulation of transferase activity GO:0051338 263 0.857
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.812
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.793
steroid esterification GO:0034433 3 0.783
Human
small molecule catabolic process GO:0044282 71 0.742
alcohol metabolic process GO:0006066 116 0.734
Mouse
superoxide anion generation GO:0042554 11 0.730
Rat
negative regulation of heart rate GO:0010459 4 0.728
hormone metabolic process GO:0042445 86 0.726
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.718
oxidation reduction process GO:0055114 342 0.698
circulatory system process GO:0003013 197 0.695
kidney epithelium development GO:0072073 121 0.688
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.685
response to peptide hormone GO:0043434 127 0.678
Mouse
regulation of hormone levels GO:0010817 211 0.677
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902218 1 0.674
lipid biosynthetic process GO:0008610 179 0.648
cellular metal ion homeostasis GO:0006875 151 0.646
Rat
regulation of lipid metabolic process GO:0019216 118 0.638
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.636
blood circulation GO:0008015 195 0.632
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.620
cellular response to hormone stimulus GO:0032870 150 0.606
Mouse
inflammatory response GO:0006954 244 0.597
hexose metabolic process GO:0019318 98 0.586
Mouse
cellular amine metabolic process GO:0044106 44 0.578
small molecule biosynthetic process GO:0044283 132 0.578
fatty acid metabolic process GO:0006631 121 0.573
fat soluble vitamin biosynthetic process GO:0042362 4 0.566
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.556
cation homeostasis GO:0055080 212 0.555
Rat
organic hydroxy compound metabolic process GO:1901615 203 0.555
Mouse
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.547
cellular chemical homeostasis GO:0055082 215 0.535
Rat
nucleobase containing small molecule metabolic process GO:0055086 352 0.534
regulation of body fluid levels GO:0050878 162 0.521
nephron development GO:0072006 109 0.518
renal tubule development GO:0061326 87 0.516
urogenital system development GO:0001655 261 0.509
steroid metabolic process GO:0008202 119 0.500
Human Mouse
purine containing compound metabolic process GO:0072521 311 0.498
monosaccharide biosynthetic process GO:0046364 44 0.497
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.495
response to alcohol GO:0097305 48 0.490
positive regulation of lipid metabolic process GO:0045834 40 0.485
response to organonitrogen compound GO:0010243 246 0.483
Mouse
glucocorticoid metabolic process GO:0008211 9 0.469
Mouse
vitamin d biosynthetic process GO:0042368 3 0.467
vascular process in circulatory system GO:0003018 62 0.459
lipid catabolic process GO:0016042 69 0.451
angiogenesis GO:0001525 201 0.448
Rat
triglyceride metabolic process GO:0006641 51 0.447
Mouse
renal system development GO:0072001 225 0.445
positive regulation of secretion by cell GO:1903532 114 0.430
regulation of blood pressure GO:0008217 93 0.426
rhythmic process GO:0048511 174 0.398
carbohydrate derivative biosynthetic process GO:1901137 183 0.389
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.386
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.381
regulation of cellular amine metabolic process GO:0033238 20 0.376
nephron epithelium development GO:0072009 92 0.376
regulation of steroid metabolic process GO:0019218 39 0.368
Human Mouse
alcohol biosynthetic process GO:0046165 43 0.365
cellular response to peptide hormone stimulus GO:0071375 92 0.364
Mouse
regulation of response to osmotic stress GO:0047484 3 0.362
apoptotic signaling pathway GO:0097190 306 0.358
Human
carboxylic acid transport GO:0046942 100 0.357
cellular carbohydrate metabolic process GO:0044262 119 0.356
Mouse
regulation of superoxide anion generation GO:0032928 4 0.353
Rat
positive regulation of kinase activity GO:0033674 155 0.345
cellular calcium ion homeostasis GO:0006874 119 0.341
cellular amino acid metabolic process GO:0006520 103 0.336
negative regulation of hydrolase activity GO:0051346 71 0.333
Mouse
peptidyl amino acid modification GO:0018193 336 0.332
calcium ion transport GO:0006816 159 0.326
Rat
cytokine production GO:0001816 319 0.321
glycerolipid metabolic process GO:0046486 122 0.320
Mouse
positive regulation of protein secretion GO:0050714 52 0.315
cellular ketone metabolic process GO:0042180 84 0.313
vitamin d3 metabolic process GO:0070640 3 0.313
response to nutrient levels GO:0031667 109 0.312
endocrine process GO:0050886 39 0.310
regulation of fatty acid metabolic process GO:0019217 28 0.309
organic acid biosynthetic process GO:0016053 86 0.309
peptide hormone processing GO:0016486 9 0.296
renal system process GO:0003014 48 0.296
response to dexamethasone GO:0071548 8 0.295
response to inorganic substance GO:0010035 96 0.292
response to osmotic stress GO:0006970 21 0.290
body fluid secretion GO:0007589 53 0.289
regulation of secretion GO:0051046 274 0.288
regulation of inflammatory response GO:0050727 147 0.285
divalent metal ion transport GO:0070838 172 0.283
Rat
response to organic cyclic compound GO:0014070 198 0.279
nucleotide metabolic process GO:0009117 332 0.279
angiotensin activated signaling pathway GO:0038166 4 0.278
sterol metabolic process GO:0016125 58 0.278
Mouse
nucleoside metabolic process GO:0009116 246 0.275
negative regulation of protein metabolic process GO:0051248 282 0.274
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.274
anion transport GO:0006820 177 0.271
acylglycerol metabolic process GO:0006639 55 0.271
Mouse
response to vitamin d GO:0033280 3 0.270
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.267
cellular response to peptide GO:1901653 92 0.263
Mouse
regulation of hydrolase activity GO:0051336 246 0.261
Mouse Rat
nitrogen compound transport GO:0071705 271 0.260
Rat
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902219 1 0.259
neutral lipid metabolic process GO:0006638 57 0.259
Mouse
chemotaxis GO:0006935 247 0.255
positive regulation of cellular amine metabolic process GO:0033240 5 0.254
cation transport GO:0006812 399 0.246
Rat
regulation of blood vessel size GO:0050880 56 0.245
carbohydrate biosynthetic process GO:0016051 74 0.243
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.242
cellular ion homeostasis GO:0006873 165 0.241
Rat
regulation of kinase activity GO:0043549 249 0.237
regulation of carbohydrate metabolic process GO:0006109 75 0.236
Mouse
alcohol catabolic process GO:0046164 16 0.233
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.229
negative regulation of systemic arterial blood pressure GO:0003085 15 0.227
ras protein signal transduction GO:0007265 77 0.226
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure GO:0002033 2 0.223
regulation of protein kinase activity GO:0045859 232 0.220
organic hydroxy compound biosynthetic process GO:1901617 77 0.219
regulation of gluconeogenesis GO:0006111 30 0.218
Mouse
response to peptide GO:1901652 136 0.215
Mouse
gluconeogenesis GO:0006094 39 0.215
Mouse
phospholipid metabolic process GO:0006644 87 0.214
small gtpase mediated signal transduction GO:0007264 97 0.213
regulation of secretion by cell GO:1903530 249 0.209
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.207
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.202
response to corticosteroid GO:0031960 20 0.202
regulation of cellular response to stress GO:0080135 159 0.201
mesonephric epithelium development GO:0072163 94 0.201
divalent inorganic cation homeostasis GO:0072507 138 0.198
heart contraction GO:0060047 93 0.198
amine metabolic process GO:0009308 45 0.195
positive regulation of metanephric glomerulus development GO:0072300 4 0.194
mesonephric tubule development GO:0072164 94 0.194
glomerulus development GO:0032835 40 0.193
regulation of apoptotic signaling pathway GO:2001233 197 0.191
Human
metal ion homeostasis GO:0055065 189 0.190
Rat
heart process GO:0003015 94 0.190
regulation of blood circulation GO:1903522 93 0.187
Rat
tissue remodeling GO:0048771 102 0.184
Rat
ribonucleoside metabolic process GO:0009119 245 0.184
organic cyclic compound catabolic process GO:1901361 295 0.181
nephron tubule morphogenesis GO:0072078 68 0.181
cellular amide metabolic process GO:0043603 58 0.178
regulation of protein transport GO:0051223 163 0.178
positive regulation of protein kinase activity GO:0045860 144 0.176
fatty acid biosynthetic process GO:0006633 41 0.173
one carbon metabolic process GO:0006730 1 0.173
renal system process involved in regulation of blood volume GO:0001977 4 0.173
ovulation from ovarian follicle GO:0001542 9 0.173
response to molecule of bacterial origin GO:0002237 143 0.173
regulation of peptidyl serine phosphorylation GO:0033135 39 0.172
regulation of tube size GO:0035150 57 0.171
rho protein signal transduction GO:0007266 32 0.171
peptidyl serine phosphorylation GO:0018105 74 0.170
peptidyl serine modification GO:0018209 83 0.170
purine nucleoside metabolic process GO:0042278 241 0.169
kidney development GO:0001822 213 0.168
positive regulation of protein phosphorylation GO:0001934 242 0.167
positive regulation of cell death GO:0010942 224 0.165
Human
receptor recycling GO:0001881 11 0.164
amide transport GO:0042886 138 0.164
glucocorticoid biosynthetic process GO:0006704 5 0.163
regulation of ion homeostasis GO:2000021 64 0.162
Rat
cofactor metabolic process GO:0051186 80 0.161
water transport GO:0006833 12 0.160
reactive oxygen species metabolic process GO:0072593 84 0.160
Rat
blood vessel morphogenesis GO:0048514 285 0.157
Rat
generation of precursor metabolites and energy GO:0006091 103 0.153
second messenger mediated signaling GO:0019932 73 0.152
glucose metabolic process GO:0006006 92 0.152
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.151
fatty acid derivative metabolic process GO:1901568 33 0.151
renal tubule morphogenesis GO:0061333 72 0.150
cytosolic calcium ion homeostasis GO:0051480 70 0.148
leukocyte migration GO:0050900 124 0.148
regulation of heart contraction GO:0008016 77 0.147
response to corticosterone GO:0051412 1 0.147
negative regulation of phosphorylation GO:0042326 166 0.144
metanephric glomerular mesangium development GO:0072223 3 0.144
glycosyl compound metabolic process GO:1901657 246 0.141
carboxylic acid catabolic process GO:0046395 51 0.141
response to lipopolysaccharide GO:0032496 128 0.141
positive regulation of systemic arterial blood pressure GO:0003084 9 0.138
positive regulation of transferase activity GO:0051347 167 0.137
response to insulin GO:0032868 100 0.136
Mouse
steroid catabolic process GO:0006706 7 0.136
carboxylic acid biosynthetic process GO:0046394 86 0.136
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.135
negative regulation of blood pressure GO:0045776 22 0.135
peptide metabolic process GO:0006518 46 0.134
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.134
cell type specific apoptotic process GO:0097285 268 0.133
regulation of system process GO:0044057 200 0.132
Rat
regulation of glucose metabolic process GO:0010906 60 0.132
Mouse
calcium ion homeostasis GO:0055074 127 0.131
hexose biosynthetic process GO:0019319 39 0.130
Mouse
negative regulation of protein modification process GO:0031400 163 0.128
lipid modification GO:0030258 65 0.128
Human
monosaccharide metabolic process GO:0005996 106 0.128
Mouse
cholesterol metabolic process GO:0008203 56 0.128
Mouse
response to steroid hormone GO:0048545 56 0.126
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.126
drug metabolic process GO:0017144 4 0.125
regulation of nucleotide metabolic process GO:0006140 169 0.124
energy derivation by oxidation of organic compounds GO:0015980 77 0.124
morphogenesis of a branching structure GO:0001763 203 0.123
metanephric glomerulus development GO:0072224 13 0.123
negative regulation of cell proliferation GO:0008285 296 0.122
response to acid chemical GO:0001101 111 0.121
carbohydrate metabolic process GO:0005975 230 0.120
Mouse
cellular homeostasis GO:0019725 240 0.119
Rat
innate immune response GO:0045087 157 0.118
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.117
positive regulation of apoptotic process GO:0043065 217 0.117
Human
nephron morphogenesis GO:0072028 69 0.116
camera type eye development GO:0043010 266 0.116
fat soluble vitamin metabolic process GO:0006775 11 0.114
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.114
response to glucocorticoid GO:0051384 20 0.113
response to drug GO:0042493 75 0.112
sensory perception GO:0007600 245 0.111
negative regulation of protein processing GO:0010955 79 0.110
Mouse
response to monosaccharide GO:0034284 67 0.110
regulation of purine nucleotide metabolic process GO:1900542 169 0.110
regulation of lipid biosynthetic process GO:0046890 54 0.109
calcitriol biosynthetic process from calciol GO:0036378 3 0.107
cellular response to carbohydrate stimulus GO:0071322 50 0.106
coenzyme metabolic process GO:0006732 52 0.106
regulation of homeostatic process GO:0032844 182 0.105
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.104
alpha amino acid metabolic process GO:1901605 59 0.103
drug catabolic process GO:0042737 2 0.103
negative regulation of endopeptidase activity GO:0010951 44 0.103
Mouse
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.103
organic acid transport GO:0015849 101 0.103
regulation of membrane potential GO:0042391 192 0.102
gland development GO:0048732 330 0.102
glutamate metabolic process GO:0006536 9 0.101
cellular response to organonitrogen compound GO:0071417 145 0.100
Mouse
muscle cell differentiation GO:0042692 261 0.100
cellular response to insulin stimulus GO:0032869 78 0.098
Mouse
positive regulation of mapk cascade GO:0043410 170 0.098
development of primary sexual characteristics GO:0045137 143 0.098
cellular response to organic cyclic compound GO:0071407 87 0.098
ribose phosphate metabolic process GO:0019693 291 0.098
regulation of lipase activity GO:0060191 15 0.097
Rat
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.097
Mouse
regulation of superoxide metabolic process GO:0090322 8 0.097
Rat
plasma lipoprotein particle remodeling GO:0034369 6 0.097
response to metal ion GO:0010038 47 0.096
mesonephros development GO:0001823 97 0.096
nephron tubule development GO:0072080 84 0.096
adrenal gland development GO:0030325 18 0.095
c21 steroid hormone biosynthetic process GO:0006700 3 0.094
cellular lipid catabolic process GO:0044242 52 0.094
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.093
Mouse
dibenzo p dioxin metabolic process GO:0018894 1 0.093
regulation of glutamate metabolic process GO:2000211 1 0.093
reactive oxygen species biosynthetic process GO:1903409 8 0.093
cell chemotaxis GO:0060326 81 0.093
response to oxidative stress GO:0006979 123 0.092
response to glucagon GO:0033762 3 0.092
protein maturation GO:0051604 176 0.092
Mouse
metanephric nephron development GO:0072210 34 0.091
vasoconstriction GO:0042310 27 0.091
cellular response to lipid GO:0071396 145 0.091
protein secretion GO:0009306 111 0.090
tissue migration GO:0090130 68 0.090
Human
regulation of metanephric glomerulus development GO:0072298 5 0.089
cholesterol homeostasis GO:0042632 44 0.089
lipid transport GO:0006869 98 0.088
response to extracellular stimulus GO:0009991 127 0.088
potassium ion homeostasis GO:0055075 4 0.087
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.086
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.086
ovulation GO:0030728 15 0.085
regulation of receptor recycling GO:0001919 8 0.084
cell adhesion GO:0007155 329 0.084
protein glycosylation GO:0006486 55 0.083
Mouse
positive regulation of monooxygenase activity GO:0032770 2 0.083
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.083
protein processing GO:0016485 163 0.083
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.082
regulation of morphogenesis of a branching structure GO:0060688 53 0.082
Human
regulation of metal ion transport GO:0010959 106 0.082
Rat
glycosylation GO:0070085 62 0.082
Mouse
unsaturated fatty acid metabolic process GO:0033559 31 0.081
positive regulation of nucleotide metabolic process GO:0045981 114 0.080
sodium ion transport GO:0006814 73 0.080
epithelial cell migration GO:0010631 63 0.080
Human
monocarboxylic acid biosynthetic process GO:0072330 61 0.080
response to water deprivation GO:0009414 1 0.079
positive regulation of hormone secretion GO:0046887 38 0.078
polysaccharide metabolic process GO:0005976 39 0.078
regulation of nitrogen cycle metabolic process GO:1903314 1 0.078
positive regulation of fatty acid oxidation GO:0046321 4 0.078
purine containing compound biosynthetic process GO:0072522 70 0.077
negative regulation of intracellular signal transduction GO:1902532 167 0.076
organonitrogen compound catabolic process GO:1901565 264 0.076
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.075
renin secretion into blood stream GO:0002001 5 0.075
ribonucleotide metabolic process GO:0009259 291 0.075
negative regulation of phosphate metabolic process GO:0045936 184 0.074
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.074
nephron epithelium morphogenesis GO:0072088 68 0.074
regulation of ion transport GO:0043269 215 0.073
Rat
purine ribonucleotide metabolic process GO:0009150 290 0.073
amino acid transport GO:0006865 61 0.072
purine nucleotide metabolic process GO:0006163 302 0.071
mammary gland duct morphogenesis GO:0060603 38 0.071
regulation of anatomical structure size GO:0090066 178 0.070
cartilage development GO:0051216 140 0.070
beta amyloid metabolic process GO:0050435 14 0.069
inorganic anion transport GO:0015698 43 0.068
sterol homeostasis GO:0055092 45 0.067
cellular response to cytokine stimulus GO:0071345 189 0.067
regulation of protein maturation GO:1903317 96 0.067
Mouse
multicellular organismal homeostasis GO:0048871 164 0.067
response to ketone GO:1901654 15 0.067
organic anion transport GO:0015711 137 0.066
cellular glucan metabolic process GO:0006073 32 0.066
axonogenesis GO:0007409 274 0.066
cellular response to monosaccharide stimulus GO:0071326 47 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
glucose homeostasis GO:0042593 128 0.065
metanephric nephron epithelium development GO:0072243 19 0.065
carbohydrate homeostasis GO:0033500 128 0.064
digestion GO:0007586 40 0.064
lipid localization GO:0010876 126 0.064
divalent inorganic cation transport GO:0072511 178 0.064
Rat
exogenous drug catabolic process GO:0042738 1 0.063
multi multicellular organism process GO:0044706 109 0.063
Rat
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.062
positive regulation of steroid metabolic process GO:0045940 5 0.062
Human
cellular response to dexamethasone stimulus GO:0071549 8 0.062
vasodilation GO:0042311 28 0.062
Rat
protein lipid complex subunit organization GO:0071825 12 0.061
folic acid containing compound metabolic process GO:0006760 3 0.061
sensory perception of pain GO:0019233 47 0.061
negative regulation of phagocytosis GO:0050765 4 0.060
cellular response to steroid hormone stimulus GO:0071383 33 0.060
maternal process involved in female pregnancy GO:0060135 32 0.060
ammonia assimilation cycle GO:0019676 2 0.059
response to estrogen GO:0043627 24 0.059
dicarboxylic acid transport GO:0006835 29 0.059
regulation of proteolysis GO:0030162 164 0.059
Mouse
renal sodium ion transport GO:0003096 2 0.059
response to starvation GO:0042594 65 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.059
regulation of protein processing GO:0070613 96 0.059
Mouse
neuron apoptotic process GO:0051402 142 0.058
organic acid catabolic process GO:0016054 51 0.058
cellular alcohol biosynthetic process GO:0044108 3 0.058
triglyceride rich lipoprotein particle remodeling GO:0034370 2 0.058
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.058
positive regulation of growth hormone secretion GO:0060124 3 0.058
energy reserve metabolic process GO:0006112 39 0.057
multicellular organism growth GO:0035264 161 0.057
insulin receptor signaling pathway GO:0008286 49 0.057
Mouse
positive regulation of peptide secretion GO:0002793 33 0.057
very low density lipoprotein particle remodeling GO:0034372 1 0.057
urea transmembrane transport GO:0071918 2 0.057
response to water GO:0009415 1 0.057
regulation of glycogen metabolic process GO:0070873 13 0.056
positive regulation of programmed cell death GO:0043068 218 0.056
Human
cellular response to cadmium ion GO:0071276 3 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.056
Human Mouse
negative regulation of proteolysis GO:0045861 74 0.056
Mouse
fat cell differentiation GO:0045444 160 0.056
skeletal system development GO:0001501 356 0.055
endothelial cell migration GO:0043542 44 0.055
Human
cyclic nucleotide metabolic process GO:0009187 59 0.055
regulation of peptide secretion GO:0002791 77 0.054
regulation of serotonin uptake GO:0051611 2 0.054
organic hydroxy compound catabolic process GO:1901616 25 0.054
cellular response to oxidative stress GO:0034599 76 0.054
cellular polysaccharide metabolic process GO:0044264 38 0.054
purine ribonucleotide biosynthetic process GO:0009152 59 0.054
ion transmembrane transport GO:0034220 361 0.054
regulation of angiotensin levels in blood GO:0002002 4 0.053
regulation of carbohydrate biosynthetic process GO:0043255 40 0.053
Mouse
signal transduction by p53 class mediator GO:0072331 51 0.053
secondary metabolic process GO:0019748 18 0.052
lipoprotein metabolic process GO:0042157 43 0.052
metanephric tubule development GO:0072170 18 0.052
cell substrate adhesion GO:0031589 130 0.052
lactation GO:0007595 25 0.052
regulation of protein localization GO:0032880 231 0.052
lipid homeostasis GO:0055088 63 0.051
positive regulation of secretion GO:0051047 130 0.051
cellular response to water deprivation GO:0042631 1 0.051
stress activated mapk cascade GO:0051403 80 0.051
Rat
macromolecule glycosylation GO:0043413 55 0.051
Mouse
cholesterol catabolic process GO:0006707 5 0.051
negative regulation of cellular amine metabolic process GO:0033239 1 0.051
ensheathment of neurons GO:0007272 76 0.050
l amino acid transport GO:0015807 32 0.050
sulfur compound biosynthetic process GO:0044272 37 0.050
glycerophospholipid metabolic process GO:0006650 71 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.050
regulation of cell motility GO:2000145 236 0.049
Human
purine nucleotide catabolic process GO:0006195 211 0.049
progesterone metabolic process GO:0042448 4 0.049
response to bile acid GO:1903412 1 0.049
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.048
fluid transport GO:0042044 14 0.048
axon ensheathment GO:0008366 76 0.048
lymphocyte migration GO:0072676 26 0.048
response to oxygen levels GO:0070482 62 0.048
action potential GO:0001508 78 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.048
peptide secretion GO:0002790 114 0.047
glycogen metabolic process GO:0005977 32 0.047
regulation of circadian sleep wake cycle GO:0042749 3 0.047
establishment of blood nerve barrier GO:0008065 3 0.047
cellular response to external stimulus GO:0071496 88 0.046
Rat
regulation of cellular catabolic process GO:0031329 242 0.046
ureteric bud development GO:0001657 94 0.046
inorganic ion transmembrane transport GO:0098660 234 0.046
plasma lipoprotein particle assembly GO:0034377 6 0.046
icosanoid metabolic process GO:0006690 33 0.045
g protein coupled receptor signaling pathway GO:0007186 243 0.045
Human Rat
nucleoside phosphate biosynthetic process GO:1901293 79 0.045
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.045
response to radiation GO:0009314 165 0.045
triglyceride homeostasis GO:0070328 15 0.045
cognition GO:0050890 149 0.045
membrane lipid metabolic process GO:0006643 53 0.045
water homeostasis GO:0030104 27 0.045
adult behavior GO:0030534 135 0.045
regulation of response to wounding GO:1903034 189 0.045
neuronal action potential GO:0019228 54 0.045
glycerolipid biosynthetic process GO:0045017 50 0.045
catecholamine metabolic process GO:0006584 30 0.044
vitamin biosynthetic process GO:0009110 7 0.044
glycoprotein metabolic process GO:0009100 116 0.044
Mouse
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.044
Human
cellular response to alcohol GO:0097306 23 0.044
general adaptation syndrome GO:0051866 2 0.044
biomineral tissue development GO:0031214 64 0.043
cellularization GO:0007349 1 0.043
negative regulation of camp mediated signaling GO:0043951 3 0.043
intracellular protein transport GO:0006886 204 0.043
Rat
dephosphorylation GO:0016311 129 0.043
negative regulation of lipid metabolic process GO:0045833 30 0.043
Mouse
regulation of angiogenesis GO:0045765 81 0.043
Rat
positive regulation of nitric oxide synthase activity GO:0051000 2 0.043
regulation of peptide transport GO:0090087 91 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.043
regulation of lipoprotein lipase activity GO:0051004 4 0.043
mineralocorticoid biosynthetic process GO:0006705 1 0.042
response to amino acid GO:0043200 37 0.042
regulation of neuron death GO:1901214 134 0.042
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.042
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.042
regulation of vasculature development GO:1901342 88 0.042
Rat
regulation of plasma lipoprotein particle levels GO:0097006 23 0.042
intrinsic apoptotic signaling pathway GO:0097193 132 0.042
protein lipid complex remodeling GO:0034368 6 0.042
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.041
Rat
nucleotide biosynthetic process GO:0009165 78 0.041
sodium ion homeostasis GO:0055078 7 0.041
Rat
regulation of metanephros development GO:0072215 15 0.041
cellular response to inorganic substance GO:0071241 37 0.041

Agt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.765
inherited metabolic disorder DOID:655 0 0.455
disease of anatomical entity DOID:7 0 0.202
Human
cardiovascular system disease DOID:1287 0 0.202
Human
lipid metabolism disorder DOID:3146 0 0.147
nervous system disease DOID:863 0 0.053
steroid inherited metabolic disorder DOID:1701 0 0.047
musculoskeletal system disease DOID:17 0 0.043
connective tissue disease DOID:65 0 0.043