Mus musculus

0 known processes

Ak3

adenylate kinase 3

(Aliases: Akl3l,AA407498,Ak3l,AK-3,Ak3l1,AI506714)

Ak3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule catabolic process GO:0044282 71 0.617
carboxylic acid catabolic process GO:0046395 51 0.548
cellular lipid metabolic process GO:0044255 323 0.405
organic acid catabolic process GO:0016054 51 0.320
cellular amino acid catabolic process GO:0009063 25 0.306
sulfur compound metabolic process GO:0006790 100 0.288
fatty acid metabolic process GO:0006631 121 0.242
monocarboxylic acid metabolic process GO:0032787 191 0.208
small molecule biosynthetic process GO:0044283 132 0.202
organic acid biosynthetic process GO:0016053 86 0.199
alcohol metabolic process GO:0006066 116 0.189
oxidation reduction process GO:0055114 342 0.171
lipid modification GO:0030258 65 0.163
alpha amino acid metabolic process GO:1901605 59 0.159
organic hydroxy compound metabolic process GO:1901615 203 0.157
cellular amino acid metabolic process GO:0006520 103 0.156
carboxylic acid biosynthetic process GO:0046394 86 0.155
glutamate biosynthetic process GO:0006537 2 0.149
lipid oxidation GO:0034440 29 0.141
monocarboxylic acid catabolic process GO:0072329 27 0.137
glutamine family amino acid biosynthetic process GO:0009084 2 0.129
fatty acid oxidation GO:0019395 28 0.119
cellular lipid catabolic process GO:0044242 52 0.106
very long chain fatty acid metabolic process GO:0000038 8 0.099
organonitrogen compound biosynthetic process GO:1901566 192 0.093
Rat
cellular modified amino acid metabolic process GO:0006575 63 0.087
fatty acid beta oxidation GO:0006635 16 0.079
cellular ketone metabolic process GO:0042180 84 0.072
lipid biosynthetic process GO:0008610 179 0.070
alpha amino acid catabolic process GO:1901606 18 0.066
protein catabolic process GO:0030163 221 0.062
ion transmembrane transport GO:0034220 361 0.062
regulation of organelle organization GO:0033043 289 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
alpha amino acid biosynthetic process GO:1901607 15 0.054
transmembrane transport GO:0055085 412 0.052
regulation of transferase activity GO:0051338 263 0.050
monocarboxylic acid biosynthetic process GO:0072330 61 0.050
sterol metabolic process GO:0016125 58 0.049
cellular amine metabolic process GO:0044106 44 0.047
engulfment of apoptotic cell GO:0043652 3 0.044
posttranscriptional regulation of gene expression GO:0010608 155 0.044
carbohydrate derivative biosynthetic process GO:1901137 183 0.044
Rat
organonitrogen compound catabolic process GO:1901565 264 0.043
striated muscle tissue development GO:0014706 293 0.042
response to organonitrogen compound GO:0010243 246 0.042
blood vessel morphogenesis GO:0048514 285 0.041
lipid catabolic process GO:0016042 69 0.040
glycoprotein biosynthetic process GO:0009101 89 0.040
thioester metabolic process GO:0035383 19 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cofactor metabolic process GO:0051186 80 0.040
dicarboxylic acid catabolic process GO:0043649 2 0.038
alcohol biosynthetic process GO:0046165 43 0.038
organic hydroxy compound biosynthetic process GO:1901617 77 0.037
carbohydrate metabolic process GO:0005975 230 0.037
muscle cell differentiation GO:0042692 261 0.037
leukocyte differentiation GO:0002521 342 0.037
regulation of cellular response to stress GO:0080135 159 0.036
multicellular organism growth GO:0035264 161 0.035
muscle tissue development GO:0060537 308 0.035
generation of precursor metabolites and energy GO:0006091 103 0.035
sulfur compound biosynthetic process GO:0044272 37 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
Human Rat
adiponectin activated signaling pathway GO:0033211 4 0.034
mitochondrial membrane organization GO:0007006 26 0.034
glycoprotein metabolic process GO:0009100 116 0.033
anion transport GO:0006820 177 0.033
membrane organization GO:0061024 245 0.033
endocytosis GO:0006897 168 0.033
phospholipid metabolic process GO:0006644 87 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
myeloid cell differentiation GO:0030099 233 0.033
chemotaxis GO:0006935 247 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
water soluble vitamin metabolic process GO:0006767 10 0.030
action potential GO:0001508 78 0.030
nucleoside metabolic process GO:0009116 246 0.029
Human Rat
amine metabolic process GO:0009308 45 0.029
response to growth factor GO:0070848 198 0.029
macromolecule catabolic process GO:0009057 281 0.029
ossification GO:0001503 216 0.029
regulation of membrane potential GO:0042391 192 0.029
cellular amino acid biosynthetic process GO:0008652 22 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.028
Human Rat
glycerolipid metabolic process GO:0046486 122 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.027
Human Rat
ribose phosphate metabolic process GO:0019693 291 0.027
Human Rat
cholesterol metabolic process GO:0008203 56 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
mitochondrion organization GO:0007005 134 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
cellular carbohydrate metabolic process GO:0044262 119 0.026
regulation of intracellular transport GO:0032386 159 0.026
cell maturation GO:0048469 127 0.026
organic anion transport GO:0015711 137 0.026
regulation of map kinase activity GO:0043405 120 0.026
ribonucleoside metabolic process GO:0009119 245 0.025
Human Rat
myeloid leukocyte differentiation GO:0002573 119 0.025
regulation of endocytosis GO:0030100 69 0.025
cellular alcohol metabolic process GO:0044107 3 0.025
response to oxidative stress GO:0006979 123 0.025
negative regulation of protein phosphorylation GO:0001933 126 0.025
cellular homeostasis GO:0019725 240 0.025
fatty acid biosynthetic process GO:0006633 41 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
negative regulation of dna replication GO:0008156 4 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
cation transport GO:0006812 399 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
regulation of transmembrane transport GO:0034762 128 0.024
apoptotic signaling pathway GO:0097190 306 0.024
regulation of lipid metabolic process GO:0019216 118 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.023
glial cell apoptotic process GO:0034349 3 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
Human Rat
regulation of mapk cascade GO:0043408 248 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
heterocycle catabolic process GO:0046700 280 0.023
cellular response to acid chemical GO:0071229 68 0.023
defense response to other organism GO:0098542 197 0.023
response to organic cyclic compound GO:0014070 198 0.022
connective tissue development GO:0061448 179 0.022
digestive tract development GO:0048565 190 0.022
regulation of protein kinase activity GO:0045859 232 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
negative regulation of cell proliferation GO:0008285 296 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
positive regulation of protein modification process GO:0031401 299 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
glycerolipid biosynthetic process GO:0045017 50 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
regulation of kinase activity GO:0043549 249 0.021
regulation of protein localization GO:0032880 231 0.021
regulation of engulfment of apoptotic cell GO:1901074 2 0.020
endomembrane system organization GO:0010256 147 0.020
lipid homeostasis GO:0055088 63 0.020
homeostasis of number of cells GO:0048872 210 0.020
ras protein signal transduction GO:0007265 77 0.020
maintenance of location GO:0051235 89 0.020
protein oligomerization GO:0051259 67 0.020
Rat
regulation of myeloid cell differentiation GO:0045637 96 0.020
myeloid cell homeostasis GO:0002262 114 0.020
protein glycosylation GO:0006486 55 0.020
establishment of protein localization to peroxisome GO:0072663 4 0.020
coenzyme metabolic process GO:0006732 52 0.020
glutamate metabolic process GO:0006536 9 0.020
regulation of cytokine production GO:0001817 266 0.019
regulation of ossification GO:0030278 112 0.019
nuclear transport GO:0051169 139 0.019
cardiac muscle tissue development GO:0048738 130 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
cell type specific apoptotic process GO:0097285 268 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
regulation of cell activation GO:0050865 289 0.019
acylglycerol metabolic process GO:0006639 55 0.019
peroxisomal transport GO:0043574 4 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
protein localization to peroxisome GO:0072662 4 0.019
lateral inhibition GO:0046331 1 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
Human Rat
dicarboxylic acid biosynthetic process GO:0043650 5 0.018
cytoplasmic transport GO:0016482 234 0.018
innate immune response GO:0045087 157 0.018
cation transmembrane transport GO:0098655 266 0.018
metal ion homeostasis GO:0055065 189 0.018
cytokine production GO:0001816 319 0.018
negative regulation of molecular function GO:0044092 258 0.018
positive regulation of glycolytic process GO:0045821 4 0.018
positive regulation of growth GO:0045927 104 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
organic acid transport GO:0015849 101 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
plasma membrane organization GO:0007009 90 0.018
fatty acid catabolic process GO:0009062 25 0.017
response to light stimulus GO:0009416 135 0.017
forebrain development GO:0030900 302 0.017
Rat
osteoclast differentiation GO:0030316 62 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
response to peptide GO:1901652 136 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
carbohydrate biosynthetic process GO:0016051 74 0.017
response to acid chemical GO:0001101 111 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
Human Rat
developmental maturation GO:0021700 193 0.017
regulation of homeostatic process GO:0032844 182 0.017
peroxisome organization GO:0007031 7 0.017
actin cytoskeleton organization GO:0030036 220 0.017
transmission of nerve impulse GO:0019226 76 0.016
cation homeostasis GO:0055080 212 0.016
glycerophospholipid biosynthetic process GO:0046474 32 0.016
regulation of hormone levels GO:0010817 211 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
Rat
macromolecule glycosylation GO:0043413 55 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.016
amide transport GO:0042886 138 0.016
anatomical structure homeostasis GO:0060249 145 0.016
epithelial cell development GO:0002064 159 0.016
protein targeting GO:0006605 143 0.016
axonogenesis GO:0007409 274 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
Human Rat
regulation of cellular amine metabolic process GO:0033238 20 0.016
response to extracellular stimulus GO:0009991 127 0.016
Rat
protein import into peroxisome matrix GO:0016558 3 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
tissue homeostasis GO:0001894 115 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
blood circulation GO:0008015 195 0.015
isoprenoid metabolic process GO:0006720 29 0.015
t cell activation GO:0042110 289 0.015
phagocytosis GO:0006909 66 0.015
lipid localization GO:0010876 126 0.015
cohesin localization to chromatin GO:0071921 1 0.015
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
substantia nigra development GO:0021762 2 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
anion transmembrane transport GO:0098656 71 0.015
gonad development GO:0008406 141 0.015
positive regulation of homeostatic process GO:0032846 64 0.015
regulation of transporter activity GO:0032409 57 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
digestive system development GO:0055123 200 0.015
protein localization to membrane GO:0072657 108 0.015
respiratory system development GO:0060541 190 0.014
cellular amide metabolic process GO:0043603 58 0.014
skin development GO:0043588 220 0.014
negative regulation of transferase activity GO:0051348 85 0.014
germ cell development GO:0007281 185 0.014
protein maturation GO:0051604 176 0.014
telencephalon development GO:0021537 186 0.014
Rat
glycosylation GO:0070085 62 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
limb morphogenesis GO:0035108 149 0.014
cellular response to external stimulus GO:0071496 88 0.014
glutamine family amino acid metabolic process GO:0009064 15 0.014
heart process GO:0003015 94 0.014
very long chain fatty acid catabolic process GO:0042760 2 0.014
single organism cell adhesion GO:0098602 156 0.014
protein targeting to peroxisome GO:0006625 4 0.014
response to nutrient levels GO:0031667 109 0.014
Rat
dna metabolic process GO:0006259 303 0.014
response to radiation GO:0009314 165 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
xenobiotic catabolic process GO:0042178 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
intracellular protein transport GO:0006886 204 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
neuromuscular process GO:0050905 99 0.013
gland development GO:0048732 330 0.013
Rat
cellular response to extracellular stimulus GO:0031668 81 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
neuron projection guidance GO:0097485 141 0.013
endochondral bone morphogenesis GO:0060350 50 0.013
digestive tract morphogenesis GO:0048546 147 0.013
developmental cell growth GO:0048588 84 0.013
regulation of binding GO:0051098 111 0.013
angiogenesis GO:0001525 201 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
Human Rat
negative regulation of immune system process GO:0002683 209 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
Human Rat
positive regulation of lymphocyte activation GO:0051251 140 0.013
regulation of hydrolase activity GO:0051336 246 0.013
defense response to bacterium GO:0042742 119 0.013
response to starvation GO:0042594 65 0.013
Rat
proteasomal protein catabolic process GO:0010498 98 0.013
multi organism behavior GO:0051705 62 0.013
negative regulation of protein modification process GO:0031400 163 0.013
protein localization to organelle GO:0033365 185 0.013
mitochondrion distribution GO:0048311 4 0.013
cellular ion homeostasis GO:0006873 165 0.013
nucleotide metabolic process GO:0009117 332 0.013
Human Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
diterpenoid metabolic process GO:0016101 24 0.012
cellular protein catabolic process GO:0044257 155 0.012
cell adhesion GO:0007155 329 0.012
sensory perception GO:0007600 245 0.012
regulation of cell adhesion GO:0030155 154 0.012
carboxylic acid transport GO:0046942 100 0.012
nitrogen compound transport GO:0071705 271 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
rho protein signal transduction GO:0007266 32 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
regulation of cell cycle GO:0051726 281 0.012
protein localization to nucleus GO:0034504 121 0.012
circulatory system process GO:0003013 197 0.012
nucleoside catabolic process GO:0009164 206 0.012
interspecies interaction between organisms GO:0044419 83 0.012
ear development GO:0043583 200 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
rna processing GO:0006396 105 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of protein oligomerization GO:0032459 4 0.012
negative regulation of kinase activity GO:0033673 81 0.012
response to peptide hormone GO:0043434 127 0.012
interleukin 8 production GO:0032637 4 0.012
leukocyte migration GO:0050900 124 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
phospholipid biosynthetic process GO:0008654 36 0.012
regulation of cell motility GO:2000145 236 0.012
mating behavior sex discrimination GO:0048047 1 0.012
regulation of plasma lipoprotein particle levels GO:0097006 23 0.012
sensory organ morphogenesis GO:0090596 242 0.011
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.011
terpenoid metabolic process GO:0006721 25 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
response to inorganic substance GO:0010035 96 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of neuron differentiation GO:0045664 281 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
erythrocyte differentiation GO:0030218 88 0.011
response to drug GO:0042493 75 0.011
regulation of protein stability GO:0031647 52 0.011
regulation of secretion by cell GO:1903530 249 0.011
lymphocyte proliferation GO:0046651 164 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
cell growth GO:0016049 130 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
myelination GO:0042552 74 0.011
actin mediated cell contraction GO:0070252 15 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.011
regulation of proteolysis GO:0030162 164 0.011
mitotic cell cycle GO:0000278 195 0.011
epidermis development GO:0008544 187 0.011
wound healing GO:0042060 157 0.011
hormone metabolic process GO:0042445 86 0.011
skeletal muscle organ development GO:0060538 163 0.011
mapk cascade GO:0000165 281 0.011
positive regulation of fatty acid oxidation GO:0046321 4 0.011
cofactor biosynthetic process GO:0051188 41 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
positive regulation of myeloid cell differentiation GO:0045639 43 0.011
spermatogenesis GO:0007283 284 0.011
bone development GO:0060348 120 0.011
membrane lipid biosynthetic process GO:0046467 32 0.011
regulation of vacuole organization GO:0044088 4 0.011
microtubule based process GO:0007017 236 0.011
appendage development GO:0048736 166 0.011
steroid biosynthetic process GO:0006694 47 0.011
sensory perception of umami taste GO:0050917 4 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
Human Rat
steroid metabolic process GO:0008202 119 0.011
amp metabolic process GO:0046033 4 0.011
Human Rat
cytokine mediated signaling pathway GO:0019221 115 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
positive regulation of ion transport GO:0043270 65 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
dicarboxylic acid metabolic process GO:0043648 18 0.010
neutral lipid metabolic process GO:0006638 57 0.010
learning or memory GO:0007611 148 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
regulation of osteoblast differentiation GO:0045667 67 0.010
divalent inorganic cation transport GO:0072511 178 0.010
fat cell differentiation GO:0045444 160 0.010
lung development GO:0030324 164 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
regulation of lymphocyte anergy GO:0002911 4 0.010
embryonic appendage morphogenesis GO:0035113 126 0.010
regulation of t cell activation GO:0050863 170 0.010
sodium ion transport GO:0006814 73 0.010

Ak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.173
inherited metabolic disorder DOID:655 0 0.065
amino acid metabolic disorder DOID:9252 0 0.031
carbohydrate metabolic disorder DOID:2978 0 0.023
disease of cellular proliferation DOID:14566 0 0.022
brain disease DOID:936 0 0.012
central nervous system disease DOID:331 0 0.012
nervous system disease DOID:863 0 0.012
disease of anatomical entity DOID:7 0 0.012
lipid metabolism disorder DOID:3146 0 0.010