Mus musculus

377 known processes

Akt1

thymoma viral proto-oncogene 1

(Aliases: PKB,Rac,PKBalpha,PKB/Akt,Akt)

Akt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.989
regulation of actin filament polymerization GO:0030833 38 0.981
Mouse
cellular amine metabolic process GO:0044106 44 0.961
regulation of anatomical structure size GO:0090066 178 0.956
Mouse Rat Fly
regulation of cellular component size GO:0032535 121 0.953
Mouse Rat Fly
ras protein signal transduction GO:0007265 77 0.945
modification dependent protein catabolic process GO:0019941 133 0.942
actin polymerization or depolymerization GO:0008154 54 0.936
Mouse
regulation of cell size GO:0008361 72 0.933
Rat Fly
carbohydrate derivative catabolic process GO:1901136 231 0.921
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.916
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.907
Human
negative regulation of synapse assembly GO:0051964 3 0.906
Fly
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.898
positive regulation of nucleotide catabolic process GO:0030813 88 0.897
Mouse
regulation of cell motility GO:2000145 236 0.890
Human Rat
regulation of interleukin 10 secretion GO:2001179 4 0.882
Mouse
regulation of cellular protein catabolic process GO:1903362 61 0.876
regulation of actin filament based process GO:0032970 99 0.870
Mouse
purine nucleotide metabolic process GO:0006163 302 0.867
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.863
regulation of nucleoside metabolic process GO:0009118 130 0.858
Mouse
regulation of actin filament length GO:0030832 45 0.847
Mouse
regulation of cell cycle GO:0051726 281 0.846
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.839
Yeast Mouse
positive regulation of gtpase activity GO:0043547 85 0.837
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.820
Mouse
regulation of cellular catabolic process GO:0031329 242 0.820
amine metabolic process GO:0009308 45 0.803
organic cyclic compound catabolic process GO:1901361 295 0.803
Yeast Mouse
positive regulation of organelle organization GO:0010638 128 0.801
Mouse
cellular response to insulin stimulus GO:0032869 78 0.800
actin cytoskeleton organization GO:0030036 220 0.798
Yeast Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.779
positive regulation of cellular amine metabolic process GO:0033240 5 0.777
regulation of actin cytoskeleton organization GO:0032956 84 0.769
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.767
Mouse
heterocycle catabolic process GO:0046700 280 0.756
Yeast Mouse
purine nucleotide catabolic process GO:0006195 211 0.748
Mouse
apoptotic mitochondrial changes GO:0008637 48 0.748
regulation of endopeptidase activity GO:0052548 89 0.737
positive regulation of vesicle fusion GO:0031340 2 0.733
Mouse
positive regulation of cellular protein catabolic process GO:1903364 34 0.729
regulation of nucleotide catabolic process GO:0030811 122 0.719
Mouse
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.715
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.709
t helper 2 cell cytokine production GO:0035745 4 0.696
Mouse
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.692
multicellular organism growth GO:0035264 161 0.681
Fly
blood circulation GO:0008015 195 0.670
Rat
positive regulation of cell projection organization GO:0031346 95 0.666
Fly
interleukin 10 secretion GO:0072608 4 0.665
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.664
Human Mouse
nucleotide metabolic process GO:0009117 332 0.662
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.654
Mouse
regulation of cell shape GO:0008360 39 0.645
Fly
response to peptide hormone GO:0043434 127 0.633
heart contraction GO:0060047 93 0.627
positive regulation of t helper 2 cell activation GO:2000570 2 0.625
Mouse
regulation of intracellular transport GO:0032386 159 0.618
Mouse
response to osmotic stress GO:0006970 21 0.618
gtp metabolic process GO:0046039 144 0.614
Mouse
cellular amino acid metabolic process GO:0006520 103 0.589
organophosphate catabolic process GO:0046434 232 0.587
Mouse
regulation of protein complex assembly GO:0043254 83 0.578
Mouse
nucleoside metabolic process GO:0009116 246 0.578
Mouse
regulation of ral gtpase activity GO:0032315 4 0.578
Mouse
protein polymerization GO:0051258 57 0.576
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.575
Mouse
energy reserve metabolic process GO:0006112 39 0.575
positive regulation of neuron projection development GO:0010976 79 0.569
Fly
actin filament polymerization GO:0030041 44 0.566
Mouse
interleukin 5 secretion GO:0072603 2 0.560
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.555
Mouse
peptidyl amino acid modification GO:0018193 336 0.555
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.553
negative regulation of filopodium assembly GO:0051490 2 0.550
Mouse
regulation of carbohydrate biosynthetic process GO:0043255 40 0.548
Human
dendrite development GO:0016358 115 0.546
Fly
cellular carbohydrate metabolic process GO:0044262 119 0.546
purine containing compound catabolic process GO:0072523 213 0.544
Mouse
neuronal action potential GO:0019228 54 0.540
ribonucleotide metabolic process GO:0009259 291 0.536
Mouse
eye photoreceptor cell development GO:0042462 31 0.527
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.527
Mouse
cellular polysaccharide metabolic process GO:0044264 38 0.518
regulation of purine nucleotide metabolic process GO:1900542 169 0.514
Mouse
macromolecule catabolic process GO:0009057 281 0.508
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.508
Mouse
asymmetric stem cell division GO:0098722 3 0.503
negative regulation of cellular amine metabolic process GO:0033239 1 0.498
positive regulation of cell migration GO:0030335 109 0.497
Human
purine nucleoside catabolic process GO:0006152 205 0.496
Mouse
purine containing compound metabolic process GO:0072521 311 0.493
Mouse
gtp catabolic process GO:0006184 143 0.490
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.489
release of cytochrome c from mitochondria GO:0001836 23 0.487
ribonucleoside triphosphate catabolic process GO:0009203 199 0.487
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.484
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.477
Mouse
regulation of glucose metabolic process GO:0010906 60 0.474
Human
interleukin 13 secretion GO:0072611 2 0.474
Mouse
negative regulation of cytoskeleton organization GO:0051494 36 0.470
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.463
regulation of proteasomal protein catabolic process GO:0061136 46 0.459
synaptic transmission GO:0007268 329 0.458
Mouse Fly
regulation of organelle organization GO:0033043 289 0.457
lipid storage GO:0019915 36 0.453
Fly
regulation of gtp catabolic process GO:0033124 113 0.442
Mouse
regulation of transferase activity GO:0051338 263 0.437
Human Rat
positive regulation of cell motility GO:2000147 116 0.436
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.434
Mouse
negative regulation of organelle organization GO:0010639 90 0.431
negative regulation of protein modification process GO:0031400 163 0.426
Human Mouse Rat
actin filament depolymerization GO:0030042 15 0.424
myelination in peripheral nervous system GO:0022011 19 0.422
positive regulation of programmed cell death GO:0043068 218 0.421
Mouse Rat
regulation of actin polymerization or depolymerization GO:0008064 45 0.420
Mouse
regulation of cell migration GO:0030334 219 0.417
Human Rat
regulation of cellular response to stress GO:0080135 159 0.413
Rat Fly
t helper 2 cell activation GO:0035712 2 0.407
Mouse
positive regulation of protein modification process GO:0031401 299 0.406
Human Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.405
vesicle fusion GO:0006906 16 0.401
Mouse
negative regulation of phosphorylation GO:0042326 166 0.399
Human Mouse Rat
negative regulation of phosphate metabolic process GO:0045936 184 0.397
Human Mouse Rat
positive regulation of interleukin 5 secretion GO:2000664 1 0.395
Mouse
circadian rhythm GO:0007623 114 0.394
Fly
response to alkaloid GO:0043279 34 0.390
Mouse
regulation of transposition GO:0010528 2 0.389
mitochondrion organization GO:0007005 134 0.388
cellular protein complex assembly GO:0043623 116 0.386
Mouse
muscle cell differentiation GO:0042692 261 0.384
regulation of dna replication GO:0006275 17 0.381
asymmetric neuroblast division GO:0055059 1 0.381
long term synaptic depression GO:0060292 13 0.378
Fly
plasma membrane long chain fatty acid transport GO:0015911 1 0.376
Human
carboxylic acid catabolic process GO:0046395 51 0.376
Human
purine ribonucleotide metabolic process GO:0009150 290 0.376
Mouse
response to organic cyclic compound GO:0014070 198 0.375
Mouse Rat
response to peptide GO:1901652 136 0.373
glycosyl compound metabolic process GO:1901657 246 0.373
Mouse
regulation of vesicle fusion GO:0031338 6 0.370
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.365
multicellular organismal signaling GO:0035637 91 0.363
negative regulation of transposition GO:0010529 2 0.361
positive regulation of interleukin 13 secretion GO:2000667 1 0.358
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.358
Mouse
regulation of cell projection organization GO:0031344 206 0.358
multicellular organismal response to stress GO:0033555 62 0.351
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.351
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.351
fatty acid transmembrane transport GO:1902001 1 0.346
Human
regulation of protein transport GO:0051223 163 0.339
Mouse
insulin receptor signaling pathway GO:0008286 49 0.338
nucleoside triphosphate metabolic process GO:0009141 230 0.333
Mouse
regulation of neuron differentiation GO:0045664 281 0.333
nucleoside phosphate catabolic process GO:1901292 222 0.332
Mouse
lymphocyte differentiation GO:0030098 242 0.330
Mouse
actin filament organization GO:0007015 113 0.314
Yeast Mouse
ribonucleotide catabolic process GO:0009261 208 0.314
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.313
small molecule catabolic process GO:0044282 71 0.312
Human
negative regulation of protein metabolic process GO:0051248 282 0.309
regulation of cellular component biogenesis GO:0044087 181 0.306
Mouse Fly
cellular macromolecule catabolic process GO:0044265 206 0.304
placenta development GO:0001890 140 0.302
purine ribonucleoside metabolic process GO:0046128 241 0.299
Mouse
cell type specific apoptotic process GO:0097285 268 0.299
Human
carbohydrate biosynthetic process GO:0016051 74 0.298
Human Rat
cellular lipid catabolic process GO:0044242 52 0.298
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.297
Mouse
cell growth GO:0016049 130 0.296
Human Mouse Rat Fly
regulation of circadian sleep wake cycle GO:0042749 3 0.295
regulation of carbohydrate metabolic process GO:0006109 75 0.294
Human
synapse assembly GO:0007416 56 0.293
Fly
chemotaxis GO:0006935 247 0.293
negative regulation of actin filament polymerization GO:0030837 11 0.293
Mouse
polysaccharide metabolic process GO:0005976 39 0.284
response to pain GO:0048265 26 0.284
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.283
Mouse
protein transmembrane transport GO:0071806 8 0.281
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.280
myotube differentiation GO:0014902 105 0.279
Fly
regulation of mrna metabolic process GO:1903311 43 0.275
Yeast
ral protein signal transduction GO:0032484 2 0.275
regulation of cell projection assembly GO:0060491 38 0.273
Mouse
anion transport GO:0006820 177 0.272
Human
glycosyl compound catabolic process GO:1901658 206 0.271
Mouse
positive regulation of fatty acid oxidation GO:0046321 4 0.271
negative regulation of fatty acid transport GO:2000192 1 0.269
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.269
Mouse
organelle assembly GO:0070925 177 0.264
Yeast
aromatic compound catabolic process GO:0019439 286 0.262
Yeast Mouse
protein targeting GO:0006605 143 0.261
Human Mouse
apoptotic signaling pathway GO:0097190 306 0.258
meiotic cell cycle GO:0051321 122 0.251
blood coagulation GO:0007596 76 0.248
Mouse
positive regulation of glycogen metabolic process GO:0070875 8 0.243
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.243
Mouse
t cell activation GO:0042110 289 0.242
Mouse
regulation of hydrolase activity GO:0051336 246 0.241
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.240
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.238
Mouse
sensory organ morphogenesis GO:0090596 242 0.236
Mouse
positive regulation of glucose metabolic process GO:0010907 21 0.236
Human
action potential GO:0001508 78 0.234
regulation of anion transport GO:0044070 27 0.234
Human
regulation of fatty acid metabolic process GO:0019217 28 0.234
Human
developmental maturation GO:0021700 193 0.234
negative regulation of actin filament depolymerization GO:0030835 9 0.232
response to organonitrogen compound GO:0010243 246 0.232
cellular response to organonitrogen compound GO:0071417 145 0.232
negative regulation of molecular function GO:0044092 258 0.231
regulation of establishment of protein localization GO:0070201 181 0.231
Human Mouse
nucleoside catabolic process GO:0009164 206 0.231
Mouse
regulation of proteolysis GO:0030162 164 0.229
lipid localization GO:0010876 126 0.224
Human Fly
regulation of mitochondrion organization GO:0010821 27 0.221
vesicle organization GO:0016050 60 0.220
Mouse
hexose metabolic process GO:0019318 98 0.220
regulation of cell cycle process GO:0010564 160 0.220
ossification GO:0001503 216 0.216
cation transport GO:0006812 399 0.216
axon ensheathment GO:0008366 76 0.212
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.211
Human
regulation of glycogen metabolic process GO:0070873 13 0.210
Human
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.208
spermatogenesis GO:0007283 284 0.208
positive regulation of chromosome organization GO:2001252 33 0.207
ribose phosphate metabolic process GO:0019693 291 0.207
Mouse
positive regulation of interleukin 10 secretion GO:2001181 1 0.207
Mouse
innate immune response GO:0045087 157 0.206
protein catabolic process GO:0030163 221 0.206
organic anion transport GO:0015711 137 0.205
Human
positive regulation of nucleotide metabolic process GO:0045981 114 0.205
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.205
Human
regulation of glucan biosynthetic process GO:0010962 7 0.205
Human
reactive oxygen species biosynthetic process GO:1903409 8 0.204
nucleocytoplasmic transport GO:0006913 139 0.204
Human
regulation of purine nucleotide catabolic process GO:0033121 122 0.203
Mouse
peptidyl serine phosphorylation GO:0018105 74 0.203
monocarboxylic acid catabolic process GO:0072329 27 0.203
Human
cellular protein catabolic process GO:0044257 155 0.202
regulation of cytoskeleton organization GO:0051493 122 0.202
Mouse
cytoplasmic transport GO:0016482 234 0.201
Human
regulation of reactive oxygen species metabolic process GO:2000377 40 0.201
positive regulation of intracellular transport GO:0032388 70 0.198
Mouse
dna metabolic process GO:0006259 303 0.197
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.195
positive regulation of protein transport GO:0051222 93 0.193
Mouse
regulation of cell growth GO:0001558 91 0.193
Human Rat Fly
spongiotrophoblast layer development GO:0060712 15 0.190
organic acid transport GO:0015849 101 0.190
Human
negative regulation of endopeptidase activity GO:0010951 44 0.187
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.187
cellular response to peptide GO:1901653 92 0.186
polysaccharide biosynthetic process GO:0000271 20 0.186
Human Rat
cell adhesion GO:0007155 329 0.186
Mouse
regulation of t cell activation GO:0050863 170 0.185
Mouse
organic acid catabolic process GO:0016054 51 0.184
Human
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.179
habituation GO:0046959 3 0.179
cellular response to interleukin 4 GO:0071353 21 0.178
photoreceptor cell differentiation GO:0046530 52 0.178
Mouse
peptidyl tyrosine modification GO:0018212 145 0.178
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.177
t cell differentiation GO:0030217 174 0.176
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.173
Mouse
fatty acid oxidation GO:0019395 28 0.173
Human
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.172
carbohydrate transport GO:0008643 62 0.168
microtubule cytoskeleton organization GO:0000226 157 0.166
Mouse
maintenance of location GO:0051235 89 0.165
Fly
positive regulation of dendrite development GO:1900006 21 0.163
regulation of circadian rhythm GO:0042752 58 0.163
wnt signaling pathway GO:0016055 188 0.163
lipid catabolic process GO:0016042 69 0.162
Human
male gamete generation GO:0048232 285 0.161
ribonucleoprotein complex subunit organization GO:0071826 28 0.159
Yeast
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.158
negative regulation of proteolysis GO:0045861 74 0.158
reproductive behavior GO:0019098 32 0.157
hemostasis GO:0007599 78 0.157
Mouse
nitric oxide biosynthetic process GO:0006809 25 0.157
Human
positive regulation of secretion GO:0051047 130 0.156
Mouse
positive regulation of intracellular protein transport GO:0090316 42 0.155
Mouse
membrane organization GO:0061024 245 0.154
multi organism reproductive behavior GO:0044705 29 0.154
positive regulation of nucleoside metabolic process GO:0045979 91 0.154
Mouse
determination of adult lifespan GO:0008340 11 0.153
Worm
nuclear transport GO:0051169 139 0.153
Human
positive regulation of neuron projection regeneration GO:0070572 2 0.153
Fly
positive regulation of cellular component biogenesis GO:0044089 94 0.152
syncytium formation by plasma membrane fusion GO:0000768 42 0.150
Fly
positive regulation of protein catabolic process GO:0045732 60 0.150
negative regulation of phosphorus metabolic process GO:0010563 184 0.150
Human Mouse Rat
modification dependent macromolecule catabolic process GO:0043632 133 0.146
regulation of protein catabolic process GO:0042176 108 0.146
positive regulation of growth GO:0045927 104 0.146
Human Rat Fly
myosin filament assembly GO:0031034 2 0.146
locomotory behavior GO:0007626 195 0.145
regulation of interleukin 5 secretion GO:2000662 2 0.145
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.144
lateral inhibition GO:0046331 1 0.142
platelet activation GO:0030168 40 0.142
Mouse
dna alkylation GO:0006305 43 0.142
multi multicellular organism process GO:0044706 109 0.141
regulation of ras gtpase activity GO:0032318 88 0.141
Mouse
monosaccharide metabolic process GO:0005996 106 0.140
regulation of cysteine type endopeptidase activity GO:2000116 65 0.139
negative regulation of protein phosphorylation GO:0001933 126 0.138
Human Mouse Rat
positive regulation of leukocyte proliferation GO:0070665 73 0.137
Mouse
regulation of lipid metabolic process GO:0019216 118 0.137
Human
negative regulation of hydrolase activity GO:0051346 71 0.136
regulation of ral protein signal transduction GO:0032485 4 0.135
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.134
Mouse
barbed end actin filament capping GO:0051016 6 0.132
fatty acid metabolic process GO:0006631 121 0.132
Human
skin development GO:0043588 220 0.131
regulation of chemotaxis GO:0050920 53 0.129
positive regulation of apoptotic process GO:0043065 217 0.129
Mouse Rat
syncytium formation GO:0006949 43 0.129
Fly
negative regulation of cellular component organization GO:0051129 194 0.129
regulation of leukocyte mediated immunity GO:0002703 104 0.129
Mouse
regulation of body fluid levels GO:0050878 162 0.128
Mouse
positive regulation of glucose import in response to insulin stimulus GO:2001275 5 0.126
Mouse
response to morphine GO:0043278 9 0.126
Mouse
positive regulation of protein targeting to membrane GO:0090314 7 0.126
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.126
Mouse
t helper 2 cell differentiation GO:0045064 12 0.125
Mouse
activation of adenylate cyclase activity GO:0007190 4 0.124
regulation of ras protein signal transduction GO:0046578 114 0.124
Mouse
response to reactive oxygen species GO:0000302 56 0.123
regulation of lymphocyte proliferation GO:0050670 117 0.120
Mouse
organelle fusion GO:0048284 28 0.119
Mouse
photoreceptor cell development GO:0042461 40 0.118
Mouse
genetic imprinting GO:0071514 27 0.118
cellular response to sterol depletion GO:0071501 4 0.118
macromolecular complex disassembly GO:0032984 43 0.117
neuron death GO:0070997 154 0.116
glucose transport GO:0015758 56 0.114
negative regulation of cellular protein metabolic process GO:0032269 247 0.114
regulation of actin filament depolymerization GO:0030834 13 0.112
regulation of mrna processing GO:0050684 41 0.111
Yeast
leukocyte activation involved in immune response GO:0002366 126 0.111
Mouse
camera type eye development GO:0043010 266 0.111
positive regulation of type 2 immune response GO:0002830 9 0.111
Mouse
multicellular organismal aging GO:0010259 24 0.110
Worm
rna splicing GO:0008380 54 0.110
meiotic nuclear division GO:0007126 115 0.110
regulation of defense response GO:0031347 233 0.110
negative regulation of protein complex disassembly GO:0043242 22 0.109
regulation of type 2 immune response GO:0002828 18 0.109
Mouse
carbohydrate metabolic process GO:0005975 230 0.108
organelle fission GO:0048285 170 0.107
embryonic skeletal system development GO:0048706 120 0.107
protein targeting to membrane GO:0006612 20 0.107
Mouse
myosin filament organization GO:0031033 3 0.106
dna methylation GO:0006306 43 0.106
intracellular protein transport GO:0006886 204 0.106
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.106
Mouse
glial cell differentiation GO:0010001 131 0.105
homotypic cell cell adhesion GO:0034109 28 0.105
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.105
positive regulation of glucose transport GO:0010828 16 0.105
Human Mouse
circulatory system process GO:0003013 197 0.104
Rat
rhythmic process GO:0048511 174 0.104
Fly
glucose import in response to insulin stimulus GO:0044381 8 0.103
Mouse
inflammatory response GO:0006954 244 0.100
dendrite regeneration GO:0031104 1 0.100
Fly
regulation of vesicle mediated transport GO:0060627 139 0.100
Mouse
rna 3 end processing GO:0031123 20 0.099
Yeast
positive regulation of proteolysis GO:0045862 85 0.099
regulation of fatty acid beta oxidation GO:0031998 1 0.099
Human
positive regulation of mapk cascade GO:0043410 170 0.098
response to isoquinoline alkaloid GO:0014072 9 0.096
Mouse
negative regulation of growth GO:0045926 99 0.094
Fly
regulation of protein depolymerization GO:1901879 26 0.093
b cell activation GO:0042113 161 0.092
Mouse
protein import GO:0017038 101 0.092
Human
interleukin 2 biosynthetic process GO:0042094 15 0.092
Mouse
response to insulin GO:0032868 100 0.092
localization within membrane GO:0051668 4 0.092
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.091
Mouse
microtubule based process GO:0007017 236 0.091
Mouse
glycogen cell differentiation involved in embryonic placenta development GO:0060709 1 0.089
regulation of protein kinase activity GO:0045859 232 0.089
Human Rat
cellular response to hormone stimulus GO:0032870 150 0.089
monosaccharide transport GO:0015749 58 0.088
glucan biosynthetic process GO:0009250 14 0.088
Human Rat
organonitrogen compound biosynthetic process GO:1901566 192 0.088
proteasomal protein catabolic process GO:0010498 98 0.087
positive regulation of cytokine production GO:0001819 174 0.087
Mouse
response to nutrient levels GO:0031667 109 0.087
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.086
negative regulation of kinase activity GO:0033673 81 0.086
Human Rat
positive regulation of lipid metabolic process GO:0045834 40 0.085
Human
regulation of rna splicing GO:0043484 37 0.085
striated muscle myosin thick filament assembly GO:0071688 1 0.084
response to interleukin 4 GO:0070670 23 0.083
regulation of t helper 2 cell differentiation GO:0045628 8 0.083
Mouse
regulation of polysaccharide metabolic process GO:0032881 13 0.082
Human
regulation of t cell differentiation GO:0045580 83 0.082
Mouse
regulation of endocytosis GO:0030100 69 0.081
heart morphogenesis GO:0003007 178 0.081
methylation GO:0032259 134 0.081
alpha beta t cell differentiation GO:0046632 69 0.081
Mouse
glucose homeostasis GO:0042593 128 0.081
protein ubiquitination GO:0016567 171 0.081
striated muscle cell development GO:0055002 125 0.081
cellular response to epidermal growth factor stimulus GO:0071364 4 0.080
mapk cascade GO:0000165 281 0.079
Rat
single organismal cell cell adhesion GO:0016337 131 0.079
Mouse
arp2 3 complex mediated actin nucleation GO:0034314 3 0.079
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.079
Human Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.078
endocytosis GO:0006897 168 0.078
sulfur compound biosynthetic process GO:0044272 37 0.077
peptidyl lysine modification GO:0018205 77 0.077
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.077
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.076
protein localization to mitochondrion GO:0070585 15 0.076
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.075
Mouse
protein localization to nucleus GO:0034504 121 0.075
Human
retina development in camera type eye GO:0060041 119 0.075
regulation of mapk cascade GO:0043408 248 0.075
Rat
gliogenesis GO:0042063 141 0.075
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.075
Human
response to radiation GO:0009314 165 0.075
Human
positive regulation of cell development GO:0010720 237 0.074
Fly
positive regulation of interleukin 5 production GO:0032754 5 0.074
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.074
Mouse
synapsis GO:0007129 34 0.074
gland development GO:0048732 330 0.073
regulation of leukocyte proliferation GO:0070663 121 0.073
Mouse
activation of ral gtpase activity GO:0032859 3 0.073
Mouse
peptidyl threonine modification GO:0018210 31 0.072
Worm
actin filament capping GO:0051693 6 0.072
glycogen biosynthetic process GO:0005978 14 0.072
Human Rat
cytoplasmic mrna processing body assembly GO:0033962 6 0.072
Yeast
regeneration GO:0031099 38 0.072
Fly
embryonic placenta development GO:0001892 98 0.071
immune effector process GO:0002252 321 0.071
Mouse
cytokine production GO:0001816 319 0.070
Mouse
single organism nuclear import GO:1902593 95 0.070
Human
positive regulation of cytokine secretion GO:0050715 41 0.070
Mouse
positive regulation of lipid catabolic process GO:0050996 6 0.069
pole plasm assembly GO:0007315 2 0.069
regulation of heart contraction GO:0008016 77 0.068
ubiquitin dependent protein catabolic process GO:0006511 129 0.068
regulation of cytokine production involved in immune response GO:0002718 26 0.067
Mouse
neural precursor cell proliferation GO:0061351 121 0.067
mitotic cell cycle GO:0000278 195 0.067
Human
dna replication GO:0006260 52 0.067
positive regulation of nervous system development GO:0051962 221 0.067
Fly
positive regulation of cell activation GO:0050867 158 0.067
Mouse
leukocyte differentiation GO:0002521 342 0.066
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.066
compound eye development GO:0048749 1 0.066
positive regulation of actin filament polymerization GO:0030838 26 0.066
positive regulation of interleukin 2 production GO:0032743 19 0.066
Mouse
mitochondrial membrane organization GO:0007006 26 0.066
regulation of actin nucleation GO:0051125 4 0.065
fatty acid catabolic process GO:0009062 25 0.064
Human
protein complex disassembly GO:0043241 40 0.064
protein localization to organelle GO:0033365 185 0.064
Human
maternal process involved in female pregnancy GO:0060135 32 0.064
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.064
Mouse
receptor internalization GO:0031623 16 0.063
hair cycle GO:0042633 90 0.063
lymphocyte proliferation GO:0046651 164 0.063
Mouse
protein kinase b signaling GO:0043491 74 0.063
platelet aggregation GO:0070527 20 0.062
Mouse
development of primary sexual characteristics GO:0045137 143 0.062
myeloid cell differentiation GO:0030099 233 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.062
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.061
anatomical structure maturation GO:0071695 49 0.061
smoothened signaling pathway GO:0007224 105 0.061
glycoprotein metabolic process GO:0009100 116 0.061
regulation of protein localization GO:0032880 231 0.060
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.060
Mouse
mrna metabolic process GO:0016071 84 0.060
Yeast
nuclear import GO:0051170 95 0.060
Human
glucose metabolic process GO:0006006 92 0.060
dna modification GO:0006304 50 0.059
positive regulation of interleukin 13 production GO:0032736 4 0.059
Mouse
actomyosin structure organization GO:0031032 56 0.059
oocyte axis specification GO:0007309 2 0.059
establishment of protein localization to membrane GO:0090150 54 0.058
Human Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.058

Akt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
diabetes mellitus DOID:9351 0 0.206
type 2 diabetes mellitus DOID:9352 0 0.206
disease of metabolism DOID:0014667 0 0.206
carbohydrate metabolism disease DOID:0050013 0 0.206
glucose metabolism disease DOID:4194 0 0.206
acquired metabolic disease DOID:0060158 0 0.206
disease of cellular proliferation DOID:14566 0 0.066
Human