Mus musculus

164 known processes

Alox15

arachidonate 15-lipoxygenase

(Aliases: 12-LO,L-12LO,Alox12l)

Alox15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inflammatory response GO:0006954 244 0.460
Mouse
defense response to other organism GO:0098542 197 0.450
immune effector process GO:0002252 321 0.404
leukocyte differentiation GO:0002521 342 0.391
positive regulation of defense response GO:0031349 124 0.358
regulation of leukocyte differentiation GO:1902105 159 0.275
positive regulation of cytokine production GO:0001819 174 0.250
cytokine production GO:0001816 319 0.220
protein citrullination GO:0018101 2 0.210
amine metabolic process GO:0009308 45 0.204
lymphocyte differentiation GO:0030098 242 0.198
regulation of multi organism process GO:0043900 111 0.197
regulation of cell activation GO:0050865 289 0.195
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.188
regulation of cytokine production GO:0001817 266 0.186
cell type specific apoptotic process GO:0097285 268 0.184
apoptotic signaling pathway GO:0097190 306 0.181
regulation of inflammatory response GO:0050727 147 0.178
cellular amino acid metabolic process GO:0006520 103 0.174
regulation of defense response GO:0031347 233 0.172
epidermis development GO:0008544 187 0.172
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.169
positive regulation of homeostatic process GO:0032846 64 0.168
positive regulation of secretion GO:0051047 130 0.167
eosinophil migration GO:0072677 3 0.160
regulation of homeostatic process GO:0032844 182 0.159
negative regulation of multi organism process GO:0043901 68 0.158
cellular response to cytokine stimulus GO:0071345 189 0.154
regulation of endocytosis GO:0030100 69 0.153
positive regulation of eosinophil migration GO:2000418 2 0.150
regulation of t cell activation GO:0050863 170 0.147
muscle tissue development GO:0060537 308 0.144
regulation of adaptive immune response GO:0002819 90 0.137
extracellular structure organization GO:0043062 148 0.132
organonitrogen compound biosynthetic process GO:1901566 192 0.131
Mouse
regulation of secretion GO:0051046 274 0.123
cellular amine metabolic process GO:0044106 44 0.122
protein secretion GO:0009306 111 0.115
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.113
innate immune response GO:0045087 157 0.111
interspecies interaction between organisms GO:0044419 83 0.110
lymphocyte mediated immunity GO:0002449 139 0.109
mapk cascade GO:0000165 281 0.108
wound healing GO:0042060 157 0.106
cellular response to growth factor stimulus GO:0071363 197 0.105
regulation of protein serine threonine kinase activity GO:0071900 157 0.103
positive regulation of lymphocyte differentiation GO:0045621 61 0.101
regulation of hormone levels GO:0010817 211 0.101
negative regulation of molecular function GO:0044092 258 0.100
stem cell maintenance GO:0019827 130 0.098
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.098
regulation of eosinophil migration GO:2000416 2 0.094
cellular homeostasis GO:0019725 240 0.092
negative regulation of cell proliferation GO:0008285 296 0.092
cellular metal ion homeostasis GO:0006875 151 0.092
macromolecule catabolic process GO:0009057 281 0.092
regulation of secretion by cell GO:1903530 249 0.091
negative regulation of cellular component organization GO:0051129 194 0.090
regulation of mapk cascade GO:0043408 248 0.087
response to molecule of bacterial origin GO:0002237 143 0.087
striated muscle tissue development GO:0014706 293 0.087
positive regulation of apoptotic process GO:0043065 217 0.086
positive regulation of inflammatory response GO:0050729 47 0.086
positive regulation of mapk cascade GO:0043410 170 0.086
positive regulation of cell activation GO:0050867 158 0.085
homeostasis of number of cells GO:0048872 210 0.084
leukocyte apoptotic process GO:0071887 71 0.084
regulation of thymocyte migration GO:2000410 2 0.083
cytokine mediated signaling pathway GO:0019221 115 0.083
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.081
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.080
t cell activation GO:0042110 289 0.079
cytokine secretion GO:0050663 72 0.078
regulation of cellular amine metabolic process GO:0033238 20 0.077
skeletal system morphogenesis GO:0048705 203 0.077
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.077
regulation of leukocyte apoptotic process GO:2000106 56 0.076
leukocyte mediated immunity GO:0002443 174 0.076
regulation of system process GO:0044057 200 0.076
positive regulation of protein kinase activity GO:0045860 144 0.075
muscle cell differentiation GO:0042692 261 0.075
defense response to bacterium GO:0042742 119 0.075
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.074
myeloid cell differentiation GO:0030099 233 0.074
endocytosis GO:0006897 168 0.072
peptidyl amino acid modification GO:0018193 336 0.071
positive regulation of kinase activity GO:0033674 155 0.071
male gamete generation GO:0048232 285 0.071
cellular calcium ion homeostasis GO:0006874 119 0.071
leukocyte activation involved in immune response GO:0002366 126 0.070
regulation of map kinase activity GO:0043405 120 0.066
skin development GO:0043588 220 0.066
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
positive regulation of cell death GO:0010942 224 0.066
leukocyte proliferation GO:0070661 172 0.065
positive regulation of thymocyte migration GO:2000412 2 0.065
regulation of lymphocyte activation GO:0051249 240 0.065
positive regulation of monocyte chemotaxis GO:0090026 2 0.064
positive regulation of immune effector process GO:0002699 107 0.064
regionalization GO:0003002 337 0.064
sequestering of metal ion GO:0051238 19 0.063
immunoglobulin mediated immune response GO:0016064 69 0.063
thymocyte migration GO:0072679 2 0.063
positive regulation of innate immune response GO:0045089 80 0.062
multicellular organismal homeostasis GO:0048871 164 0.061
regulation of cell cycle GO:0051726 281 0.060
adaptive immune response GO:0002250 155 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.060
response to lipopolysaccharide GO:0032496 128 0.060
regulation of protein kinase activity GO:0045859 232 0.060
regulation of t cell differentiation GO:0045580 83 0.060
regulation of organelle organization GO:0033043 289 0.058
cell recognition GO:0008037 83 0.056
sequestering of calcium ion GO:0051208 18 0.056
positive regulation of protein secretion GO:0050714 52 0.056
leukotriene metabolic process GO:0006691 7 0.055
Mouse
positive regulation of transferase activity GO:0051347 167 0.055
regulation of cellular component size GO:0032535 121 0.055
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.055
maintenance of location GO:0051235 89 0.055
cellular response to external stimulus GO:0071496 88 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
epithelial cell proliferation GO:0050673 174 0.054
cellular modified amino acid biosynthetic process GO:0042398 12 0.054
regulation of response to wounding GO:1903034 189 0.053
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.053
small molecule biosynthetic process GO:0044283 132 0.053
hemostasis GO:0007599 78 0.053
Mouse
germ cell development GO:0007281 185 0.053
b cell mediated immunity GO:0019724 71 0.053
chemotaxis GO:0006935 247 0.052
g protein coupled receptor signaling pathway GO:0007186 243 0.052
skeletal system development GO:0001501 356 0.052
carboxylic acid biosynthetic process GO:0046394 86 0.051
anion transport GO:0006820 177 0.051
protein processing GO:0016485 163 0.051
t cell mediated immunity GO:0002456 50 0.051
monocarboxylic acid metabolic process GO:0032787 191 0.051
protein catabolic process GO:0030163 221 0.051
response to growth factor GO:0070848 198 0.050
oxidation reduction process GO:0055114 342 0.050
regulation of ion transport GO:0043269 215 0.050
positive regulation of jun kinase activity GO:0043507 30 0.050
negative regulation of growth GO:0045926 99 0.050
positive regulation of response to wounding GO:1903036 66 0.050
response to transforming growth factor beta GO:0071559 88 0.050
regulation of intracellular transport GO:0032386 159 0.049
organic anion transport GO:0015711 137 0.049
platelet activation GO:0030168 40 0.049
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.049
anatomical structure homeostasis GO:0060249 145 0.049
cellular amino acid biosynthetic process GO:0008652 22 0.049
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.048
myeloid leukocyte differentiation GO:0002573 119 0.048
muscle system process GO:0003012 141 0.048
regulation of vesicle mediated transport GO:0060627 139 0.048
membrane organization GO:0061024 245 0.047
cellular ion homeostasis GO:0006873 165 0.047
activation of mapk activity GO:0000187 59 0.047
fatty acid metabolic process GO:0006631 121 0.047
single organismal cell cell adhesion GO:0016337 131 0.046
Mouse Rat
humoral immune response GO:0006959 57 0.046
interleukin 8 production GO:0032637 4 0.046
cell cell recognition GO:0009988 44 0.045
positive regulation of map kinase activity GO:0043406 84 0.045
positive regulation of cell cycle GO:0045787 92 0.045
positive regulation of cytokine secretion GO:0050715 41 0.044
positive regulation of programmed cell death GO:0043068 218 0.044
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.044
cytoplasmic transport GO:0016482 234 0.044
gland development GO:0048732 330 0.043
alpha beta t cell differentiation GO:0046632 69 0.043
mature dendritic cell differentiation GO:0097029 3 0.043
skeletal muscle organ development GO:0060538 163 0.043
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.043
activation of immune response GO:0002253 138 0.043
cytokine biosynthetic process GO:0042089 68 0.043
epithelial tube morphogenesis GO:0060562 303 0.043
negative regulation of phagocytosis GO:0050765 4 0.043
cation homeostasis GO:0055080 212 0.042
t cell proliferation GO:0042098 120 0.042
positive regulation of lymphocyte activation GO:0051251 140 0.042
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.042
protein maturation GO:0051604 176 0.041
actin filament organization GO:0007015 113 0.041
regulation of lymphocyte mediated immunity GO:0002706 84 0.041
negative regulation of homeostatic process GO:0032845 71 0.041
regulation of transferase activity GO:0051338 263 0.041
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.040
bone development GO:0060348 120 0.040
lymphocyte apoptotic process GO:0070227 54 0.040
leukotriene production involved in inflammatory response GO:0002540 2 0.040
Mouse
kidney development GO:0001822 213 0.040
glycerolipid metabolic process GO:0046486 122 0.040
cellular ketone metabolic process GO:0042180 84 0.039
release of sequestered calcium ion into cytosol GO:0051209 42 0.039
positive regulation of t cell activation GO:0050870 101 0.039
immune response regulating signaling pathway GO:0002764 125 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.039
innate immune response in mucosa GO:0002227 3 0.039
hormone metabolic process GO:0042445 86 0.039
canonical wnt signaling pathway GO:0060070 130 0.039
developmental maturation GO:0021700 193 0.039
myotube cell development GO:0014904 60 0.039
regulation of kinase activity GO:0043549 249 0.038
glycoprotein metabolic process GO:0009100 116 0.038
regulation of cell motility GO:2000145 236 0.038
cell maturation GO:0048469 127 0.038
positive regulation of intracellular transport GO:0032388 70 0.038
regulation of mitotic cell cycle GO:0007346 126 0.038
negative regulation of immune system process GO:0002683 209 0.037
ossification GO:0001503 216 0.037
morphogenesis of a branching structure GO:0001763 203 0.037
positive regulation of protein modification process GO:0031401 299 0.037
lipid biosynthetic process GO:0008610 179 0.037
metal ion homeostasis GO:0055065 189 0.037
angiogenesis GO:0001525 201 0.037
positive regulation of secretion by cell GO:1903532 114 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
extracellular matrix organization GO:0030198 147 0.036
axonogenesis GO:0007409 274 0.036
fat cell differentiation GO:0045444 160 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.035
t helper 2 cell cytokine production GO:0035745 4 0.034
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.034
sphingolipid biosynthetic process GO:0030148 26 0.034
Mouse
unsaturated fatty acid metabolic process GO:0033559 31 0.034
glycerolipid biosynthetic process GO:0045017 50 0.034
glycoprotein biosynthetic process GO:0009101 89 0.034
alcohol metabolic process GO:0006066 116 0.034
regulation of leukocyte proliferation GO:0070663 121 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
cellular divalent inorganic cation homeostasis GO:0072503 127 0.034
defense response to fungus GO:0050832 12 0.034
locomotory behavior GO:0007626 195 0.034
leukotriene biosynthetic process GO:0019370 5 0.034
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.034
renal system development GO:0072001 225 0.033
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.033
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.033
urogenital system development GO:0001655 261 0.033
response to acid chemical GO:0001101 111 0.033
negative regulation of cytokine production GO:0001818 84 0.033
nuclear division GO:0000280 158 0.033
single organism cell adhesion GO:0098602 156 0.032
Mouse Rat
spermatogenesis GO:0007283 284 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
organ or tissue specific immune response GO:0002251 13 0.032
regulation of cytokine secretion GO:0050707 61 0.032
cellular lipid metabolic process GO:0044255 323 0.032
negative regulation of cell activation GO:0050866 111 0.032
Mouse
regulation of protein secretion GO:0050708 82 0.032
cardiac muscle tissue development GO:0048738 130 0.032
cellular response to molecule of bacterial origin GO:0071219 83 0.032
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.032
syncytium formation by plasma membrane fusion GO:0000768 42 0.032
regulation of natural killer cell chemotaxis GO:2000501 1 0.031
organelle localization GO:0051640 179 0.031
wnt signaling pathway GO:0016055 188 0.031
regulation of myeloid cell differentiation GO:0045637 96 0.031
leukocyte mediated cytotoxicity GO:0001909 62 0.031
metencephalon development GO:0022037 89 0.031
activation of jun kinase activity GO:0007257 15 0.031
cellular response to biotic stimulus GO:0071216 92 0.031
myeloid leukocyte migration GO:0097529 57 0.031
toll like receptor signaling pathway GO:0002224 38 0.031
intracellular protein transport GO:0006886 204 0.030
dna metabolic process GO:0006259 303 0.030
jnk cascade GO:0007254 72 0.030
organelle fission GO:0048285 170 0.030
cartilage development GO:0051216 140 0.030
positive regulation of cell motility GO:2000147 116 0.030
peptidyl serine modification GO:0018209 83 0.030
myeloid cell homeostasis GO:0002262 114 0.030
t cell apoptotic process GO:0070231 39 0.030
regulation of binding GO:0051098 111 0.030
gliogenesis GO:0042063 141 0.030
leukocyte migration GO:0050900 124 0.030
cell killing GO:0001906 67 0.029
lymphocyte activation involved in immune response GO:0002285 93 0.029
negative regulation of prostatic bud formation GO:0060686 4 0.029
regulation of myeloid leukocyte differentiation GO:0002761 58 0.029
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.029
regulation of body fluid levels GO:0050878 162 0.029
Mouse
oocyte construction GO:0007308 2 0.029
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.029
regulation of epithelial cell proliferation GO:0050678 141 0.029
regulation of immunoglobulin mediated immune response GO:0002889 37 0.028
cytosolic calcium ion homeostasis GO:0051480 70 0.028
response to inorganic substance GO:0010035 96 0.028
calcium ion homeostasis GO:0055074 127 0.028
cytokine metabolic process GO:0042107 71 0.028
muscle fiber development GO:0048747 76 0.028
regulation of ossification GO:0030278 112 0.028
regulation of proteolysis GO:0030162 164 0.027
regulation of bone resorption GO:0045124 24 0.027
developmental growth involved in morphogenesis GO:0060560 138 0.027
morphogenesis of a branching epithelium GO:0061138 193 0.027
citrulline metabolic process GO:0000052 3 0.027
peptide metabolic process GO:0006518 46 0.027
membrane lipid metabolic process GO:0006643 53 0.027
Mouse
positive regulation of protein transport GO:0051222 93 0.027
positive regulation of leukocyte mediated immunity GO:0002705 70 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
negative regulation of protein modification process GO:0031400 163 0.026
calcium ion transport into cytosol GO:0060402 48 0.026
blood coagulation GO:0007596 76 0.026
Mouse
t helper cell differentiation GO:0042093 28 0.026
regulation of cellular response to growth factor stimulus GO:0090287 82 0.026
synaptic transmission GO:0007268 329 0.026
cellular amide metabolic process GO:0043603 58 0.026
calcium ion transport GO:0006816 159 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
activation of innate immune response GO:0002218 56 0.026
cation transport GO:0006812 399 0.026
unsaturated fatty acid biosynthetic process GO:0006636 15 0.026
regulation of protein localization GO:0032880 231 0.026
killing by host of symbiont cells GO:0051873 11 0.025
phagocytosis GO:0006909 66 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
t cell differentiation GO:0030217 174 0.025
respiratory system development GO:0060541 190 0.025
cell activation involved in immune response GO:0002263 126 0.025
disruption by host of symbiont cells GO:0051852 11 0.025
lipoxin a4 biosynthetic process GO:2001303 1 0.025
negative regulation of nervous system development GO:0051961 156 0.025
prevention of polyspermy GO:0060468 4 0.025
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.025
lymphocyte proliferation GO:0046651 164 0.024
alpha beta t cell activation GO:0046631 91 0.024
neuron projection guidance GO:0097485 141 0.024
regulation of angiotensin levels in blood GO:0002002 4 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
regulation of engulfment of apoptotic cell GO:1901074 2 0.024
mitotic cell cycle process GO:1903047 159 0.024
establishment of skin barrier GO:0061436 14 0.024
Mouse
action potential GO:0001508 78 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
regulation of cytoplasmic transport GO:1903649 112 0.024
regulation of ion transmembrane transporter activity GO:0032412 54 0.024
endomembrane system organization GO:0010256 147 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
female gamete generation GO:0007292 74 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
regulation of chloride transport GO:2001225 2 0.024
myotube differentiation GO:0014902 105 0.024
cation transmembrane transport GO:0098655 266 0.024
coagulation GO:0050817 78 0.024
Mouse
gastrulation GO:0007369 116 0.023
icosanoid metabolic process GO:0006690 33 0.023
aromatic compound catabolic process GO:0019439 286 0.023
ceramide biosynthetic process GO:0046513 20 0.023
Mouse
cellular response to hormone stimulus GO:0032870 150 0.023
engulfment of apoptotic cell GO:0043652 3 0.023
regulation of cell cycle process GO:0010564 160 0.023
blood vessel morphogenesis GO:0048514 285 0.023
limb development GO:0060173 166 0.023
cellular modified amino acid metabolic process GO:0006575 63 0.023
astrocyte cell migration GO:0043615 3 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
positive regulation of interleukin 8 production GO:0032757 2 0.023
regulation of calcium ion transport GO:0051924 69 0.023
positive regulation of leukocyte proliferation GO:0070665 73 0.023
carbohydrate metabolic process GO:0005975 230 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.023
embryonic placenta development GO:0001892 98 0.023
transmembrane transport GO:0055085 412 0.022
oocyte axis specification GO:0007309 2 0.022
regulation of t helper 2 cell cytokine production GO:2000551 3 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
divalent metal ion transport GO:0070838 172 0.022
sensory organ morphogenesis GO:0090596 242 0.022
leukocyte homeostasis GO:0001776 79 0.022
hindbrain development GO:0030902 128 0.022
metanephros development GO:0001656 79 0.022
lipoxygenase pathway GO:0019372 5 0.022
ras protein signal transduction GO:0007265 77 0.022
negative regulation of organelle organization GO:0010639 90 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.022
compound eye development GO:0048749 1 0.022
binding of sperm to zona pellucida GO:0007339 34 0.022
cerebellum development GO:0021549 77 0.022
purine containing compound metabolic process GO:0072521 311 0.022
bone morphogenesis GO:0060349 78 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
mucosal immune response GO:0002385 13 0.022
neuron migration GO:0001764 122 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
glial cell differentiation GO:0010001 131 0.021
b cell differentiation GO:0030183 78 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.021
translation GO:0006412 93 0.021
regulation of metal ion transport GO:0010959 106 0.021
organic acid biosynthetic process GO:0016053 86 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
regulation of protein catabolic process GO:0042176 108 0.021
cellular response to extracellular stimulus GO:0031668 81 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of angiogenesis GO:0045765 81 0.021
regulation of neuron differentiation GO:0045664 281 0.021
ion transmembrane transport GO:0034220 361 0.021
actomyosin structure organization GO:0031032 56 0.021
erythrocyte differentiation GO:0030218 88 0.021
branching morphogenesis of an epithelial tube GO:0048754 159 0.021
cell adhesion GO:0007155 329 0.021
Mouse Rat
regulation of establishment of protein localization GO:0070201 181 0.021
organelle assembly GO:0070925 177 0.021
cd4 positive alpha beta t cell activation GO:0035710 45 0.021
protein localization to plasma membrane GO:0072659 57 0.020
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.020
cellular chemical homeostasis GO:0055082 215 0.020
nephron epithelium morphogenesis GO:0072088 68 0.020
protein ubiquitination GO:0016567 171 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
response to organic cyclic compound GO:0014070 198 0.020
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.020
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.020
striated muscle cell development GO:0055002 125 0.020
positive regulation of keratinocyte proliferation GO:0010838 4 0.020
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
meiotic nuclear division GO:0007126 115 0.020
regulation of monocyte chemotaxis GO:0090025 3 0.020
sclerotome development GO:0061056 4 0.020
regulation of transmembrane transport GO:0034762 128 0.020
glycerophospholipid metabolic process GO:0006650 71 0.020
connective tissue development GO:0061448 179 0.020
regulation of vasculature development GO:1901342 88 0.019
regulation of canonical wnt signaling pathway GO:0060828 82 0.019
regulation of muscle tissue development GO:1901861 97 0.019
fatty acid biosynthetic process GO:0006633 41 0.019
placenta development GO:0001890 140 0.019
odontogenesis of dentin containing tooth GO:0042475 66 0.019
cell fate commitment GO:0045165 210 0.019
regulation of protein transport GO:0051223 163 0.019
digestive tract development GO:0048565 190 0.019
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.019
regulation of production of molecular mediator of immune response GO:0002700 65 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
terpenoid metabolic process GO:0006721 25 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
regulation of cell migration GO:0030334 219 0.019
cell cell adhesion GO:0098609 41 0.019
sperm egg recognition GO:0035036 37 0.019
pancreatic pp cell fate commitment GO:0003329 2 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.019
regulation of myotube differentiation GO:0010830 62 0.019
response to organonitrogen compound GO:0010243 246 0.019
cardiac chamber morphogenesis GO:0003206 93 0.019
exocytosis GO:0006887 121 0.019
regulation of transporter activity GO:0032409 57 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.019
cellular response to interleukin 4 GO:0071353 21 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
t cell differentiation in thymus GO:0033077 77 0.018
negative regulation of cell cycle GO:0045786 123 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.018
renal tubule morphogenesis GO:0061333 72 0.018
regulation of phagocytosis GO:0050764 33 0.018
organic acid catabolic process GO:0016054 51 0.018
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.018
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.018
neutrophil mediated immunity GO:0002446 19 0.018
signal transduction in absence of ligand GO:0038034 55 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
nucleotide metabolic process GO:0009117 332 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
negative regulation of response to wounding GO:1903035 77 0.018
Mouse
positive regulation of b cell chemotaxis GO:2000538 2 0.018
regulation of translation GO:0006417 71 0.018
ureteric bud development GO:0001657 94 0.018
cytosolic calcium ion transport GO:0060401 48 0.018
regulation of angiotensin metabolic process GO:0060177 4 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of interleukin 1 alpha production GO:0032650 4 0.018
response to extracellular stimulus GO:0009991 127 0.018
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.018
actin cytoskeleton organization GO:0030036 220 0.018
positive regulation of protein kinase b signaling GO:0051897 32 0.018
myeloid leukocyte mediated immunity GO:0002444 42 0.017
nephron development GO:0072006 109 0.017

Alox15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.028
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.022
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
blood coagulation disease DOID:1247 0 0.021
hematopoietic system disease DOID:74 0 0.021
connective tissue disease DOID:65 0 0.018