Mus musculus

80 known processes

Alox8

arachidonate 8-lipoxygenase

(Aliases: Alox15b,8S-LOX,8-LOX)

Alox8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein transport GO:0051223 163 0.362
Human
intermediate filament cytoskeleton organization GO:0045104 26 0.342
positive regulation of secretion GO:0051047 130 0.323
Human
cellular ion homeostasis GO:0006873 165 0.313
cytokine production GO:0001816 319 0.301
Human
synaptic transmission GO:0007268 329 0.283
epithelial cell development GO:0002064 159 0.278
negative regulation of cell proliferation GO:0008285 296 0.276
Human
regulation of system process GO:0044057 200 0.268
regulation of defense response GO:0031347 233 0.243
g protein coupled receptor signaling pathway GO:0007186 243 0.227
regulation of homeostatic process GO:0032844 182 0.221
regulation of cell activation GO:0050865 289 0.211
regulation of cytokine production GO:0001817 266 0.199
Human
intermediate filament based process GO:0045103 27 0.187
membrane organization GO:0061024 245 0.175
Mouse
metal ion homeostasis GO:0055065 189 0.174
muscle system process GO:0003012 141 0.172
intermediate filament organization GO:0045109 15 0.169
positive regulation of cytokine production GO:0001819 174 0.167
Human
cellular divalent inorganic cation homeostasis GO:0072503 127 0.160
regulation of secretion by cell GO:1903530 249 0.156
Human
cellular homeostasis GO:0019725 240 0.148
cation transport GO:0006812 399 0.143
cytokine mediated signaling pathway GO:0019221 115 0.141
response to molecule of bacterial origin GO:0002237 143 0.141
muscle cell differentiation GO:0042692 261 0.135
apoptotic signaling pathway GO:0097190 306 0.134
inflammatory response GO:0006954 244 0.133
oxidation reduction process GO:0055114 342 0.124
leukocyte differentiation GO:0002521 342 0.124
regulation of blood pressure GO:0008217 93 0.121
camera type eye development GO:0043010 266 0.119
regulation of inflammatory response GO:0050727 147 0.119
response to inorganic substance GO:0010035 96 0.117
circulatory system process GO:0003013 197 0.117
visual perception GO:0007601 52 0.116
regulation of leukocyte proliferation GO:0070663 121 0.114
wound healing GO:0042060 157 0.114
Mouse
regulation of protein localization GO:0032880 231 0.114
Human
carboxylic acid biosynthetic process GO:0046394 86 0.113
Mouse Rat
protein secretion GO:0009306 111 0.112
Human
amine metabolic process GO:0009308 45 0.107
regulation of cellular amine metabolic process GO:0033238 20 0.105
cation homeostasis GO:0055080 212 0.104
regulation of establishment of protein localization GO:0070201 181 0.103
Human
cellular chemical homeostasis GO:0055082 215 0.101
cellular lipid metabolic process GO:0044255 323 0.101
olfactory learning GO:0008355 2 0.100
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.098
regulation of lymphocyte proliferation GO:0050670 117 0.098
regulation of cellular amino acid metabolic process GO:0006521 5 0.097
gland development GO:0048732 330 0.097
regulation of cellular ketone metabolic process GO:0010565 66 0.095
sensory perception GO:0007600 245 0.092
response to organonitrogen compound GO:0010243 246 0.091
regulation of ion homeostasis GO:2000021 64 0.090
extrinsic apoptotic signaling pathway GO:0097191 126 0.089
immune effector process GO:0002252 321 0.088
embryonic organ morphogenesis GO:0048562 276 0.088
organic hydroxy compound metabolic process GO:1901615 203 0.087
Mouse
cellular ketone metabolic process GO:0042180 84 0.087
ion transmembrane transport GO:0034220 361 0.087
negative regulation of epithelial cell proliferation GO:0050680 64 0.087
regulation of ion transport GO:0043269 215 0.085
carbohydrate metabolic process GO:0005975 230 0.085
cellular response to cytokine stimulus GO:0071345 189 0.081
positive regulation of lymphocyte activation GO:0051251 140 0.081
single organism cell adhesion GO:0098602 156 0.081
transmembrane transport GO:0055085 412 0.080
nitrogen compound transport GO:0071705 271 0.080
kidney development GO:0001822 213 0.077
regulation of secretion GO:0051046 274 0.075
Human
muscle contraction GO:0006936 101 0.075
cellular amine metabolic process GO:0044106 44 0.074
regulation of transferase activity GO:0051338 263 0.074
defense response to other organism GO:0098542 197 0.073
regulation of response to wounding GO:1903034 189 0.073
positive regulation of protein phosphorylation GO:0001934 242 0.073
positive regulation of cell activation GO:0050867 158 0.072
response to lipopolysaccharide GO:0032496 128 0.072
sa node cell action potential GO:0086015 4 0.071
regulation of muscle system process GO:0090257 80 0.070
leukocyte proliferation GO:0070661 172 0.070
regulation of nucleotide metabolic process GO:0006140 169 0.070
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
regulation of renal sodium excretion GO:0035813 3 0.070
cellular response to lipid GO:0071396 145 0.070
hair follicle morphogenesis GO:0031069 29 0.069
regulation of protein secretion GO:0050708 82 0.069
Human
positive regulation of protein modification process GO:0031401 299 0.068
renal system development GO:0072001 225 0.067
urogenital system development GO:0001655 261 0.067
angiogenesis GO:0001525 201 0.066
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.066
peptidyl amino acid modification GO:0018193 336 0.064
cell type specific apoptotic process GO:0097285 268 0.064
fatty acid biosynthetic process GO:0006633 41 0.063
Mouse Rat
ear development GO:0043583 200 0.062
cytoplasmic transport GO:0016482 234 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
divalent inorganic cation homeostasis GO:0072507 138 0.061
cellular response to organonitrogen compound GO:0071417 145 0.060
response to metal ion GO:0010038 47 0.060
cellular response to calcium ion GO:0071277 14 0.060
regulation of muscle contraction GO:0006937 49 0.059
sequestering of calcium ion GO:0051208 18 0.058
hepatocyte apoptotic process GO:0097284 11 0.058
ras protein signal transduction GO:0007265 77 0.058
response to organic cyclic compound GO:0014070 198 0.058
t cell proliferation GO:0042098 120 0.058
negative regulation of phosphate metabolic process GO:0045936 184 0.058
cellular metal ion homeostasis GO:0006875 151 0.054
cellular calcium ion homeostasis GO:0006874 119 0.053
regulation of blood circulation GO:1903522 93 0.053
lymphocyte proliferation GO:0046651 164 0.053
g protein coupled receptor internalization GO:0002031 3 0.053
ribose phosphate metabolic process GO:0019693 291 0.052
negative regulation of inflammatory response GO:0050728 61 0.052
calcium ion homeostasis GO:0055074 127 0.051
monocarboxylic acid metabolic process GO:0032787 191 0.051
digestive tract development GO:0048565 190 0.050
cytosolic calcium ion homeostasis GO:0051480 70 0.050
regulation of carbohydrate metabolic process GO:0006109 75 0.050
myeloid cell differentiation GO:0030099 233 0.049
endomembrane system organization GO:0010256 147 0.049
guanosine containing compound metabolic process GO:1901068 144 0.049
regulation of thyroid hormone generation GO:2000609 4 0.048
positive regulation of camp metabolic process GO:0030816 19 0.048
myeloid leukocyte differentiation GO:0002573 119 0.048
ear morphogenesis GO:0042471 118 0.048
regulation of tube size GO:0035150 57 0.048
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.046
negative regulation of response to wounding GO:1903035 77 0.045
t cell differentiation GO:0030217 174 0.045
blood circulation GO:0008015 195 0.045
sensory perception of sound GO:0007605 97 0.045
hematopoietic progenitor cell differentiation GO:0002244 143 0.045
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.045
hexose transport GO:0008645 56 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.044
vascular process in circulatory system GO:0003018 62 0.044
regulation of b cell proliferation GO:0030888 39 0.044
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.044
multicellular organismal homeostasis GO:0048871 164 0.044
multi multicellular organism process GO:0044706 109 0.044
plasma membrane organization GO:0007009 90 0.044
negative regulation of homeostatic process GO:0032845 71 0.044
sequestering of metal ion GO:0051238 19 0.043
cellular response to insulin stimulus GO:0032869 78 0.043
purine nucleotide biosynthetic process GO:0006164 65 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.043
monosaccharide transport GO:0015749 58 0.042
cellular response to hormone stimulus GO:0032870 150 0.042
regulation of t cell activation GO:0050863 170 0.042
renal system process GO:0003014 48 0.042
regulation of keratinocyte differentiation GO:0045616 11 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
regulation of systemic arterial blood pressure GO:0003073 61 0.042
regulation of heart contraction GO:0008016 77 0.041
embryonic placenta development GO:0001892 98 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
membrane depolarization GO:0051899 64 0.041
glial cell development GO:0021782 54 0.041
response to extracellular stimulus GO:0009991 127 0.040
regulation of epithelial cell proliferation GO:0050678 141 0.040
negative regulation of cytokine production GO:0001818 84 0.039
negative regulation of immune system process GO:0002683 209 0.039
Mouse
bone remodeling GO:0046849 53 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.038
positive regulation of cell motility GO:2000147 116 0.038
associative learning GO:0008306 61 0.038
regulation of cell motility GO:2000145 236 0.038
regulation of ras protein signal transduction GO:0046578 114 0.038
heart process GO:0003015 94 0.038
neurotransmitter transport GO:0006836 76 0.037
t cell activation GO:0042110 289 0.037
purine containing compound metabolic process GO:0072521 311 0.037
mapk cascade GO:0000165 281 0.037
small molecule biosynthetic process GO:0044283 132 0.037
Mouse Rat
negative regulation of secretion GO:0051048 61 0.037
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.037
nuclear transport GO:0051169 139 0.036
epithelial cell proliferation GO:0050673 174 0.036
phenol containing compound metabolic process GO:0018958 60 0.036
detection of abiotic stimulus GO:0009582 60 0.036
carbohydrate transport GO:0008643 62 0.036
placenta development GO:0001890 140 0.036
regulation of cytokine secretion GO:0050707 61 0.035
Human
protein localization to membrane GO:0072657 108 0.035
negative regulation of cell cycle GO:0045786 123 0.035
Human
striated muscle tissue development GO:0014706 293 0.035
central nervous system neuron differentiation GO:0021953 162 0.035
cell activation involved in immune response GO:0002263 126 0.035
positive regulation of cytokine secretion GO:0050715 41 0.035
Human
cytokine secretion GO:0050663 72 0.035
Human
regulation of b cell activation GO:0050864 81 0.034
multicellular organism growth GO:0035264 161 0.034
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.034
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.034
learning or memory GO:0007611 148 0.034
response to testosterone GO:0033574 3 0.034
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.034
regulation of blood vessel size GO:0050880 56 0.034
leukocyte activation involved in immune response GO:0002366 126 0.034
response to acid chemical GO:0001101 111 0.034
neuron neuron synaptic transmission GO:0007270 69 0.034
blastocyst development GO:0001824 80 0.033
regulation of cell migration GO:0030334 219 0.033
response to nutrient levels GO:0031667 109 0.033
heterocycle catabolic process GO:0046700 280 0.033
negative regulation of secretion by cell GO:1903531 54 0.033
renal sodium excretion GO:0035812 3 0.033
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.033
positive regulation of wnt signaling pathway GO:0030177 45 0.033
water homeostasis GO:0030104 27 0.033
Mouse
response to calcium ion GO:0051592 20 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.032
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.032
positive regulation of nucleotide metabolic process GO:0045981 114 0.032
forebrain development GO:0030900 302 0.032
regulation of metal ion transport GO:0010959 106 0.032
regulation of kinase activity GO:0043549 249 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.031
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.031
generation of precursor metabolites and energy GO:0006091 103 0.031
protein oligomerization GO:0051259 67 0.031
positive regulation of nervous system development GO:0051962 221 0.031
sensory perception of mechanical stimulus GO:0050954 107 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
morphogenesis of a branching structure GO:0001763 203 0.030
nucleoside metabolic process GO:0009116 246 0.030
ribonucleotide biosynthetic process GO:0009260 59 0.030
regulation of cell cycle GO:0051726 281 0.030
Human
regulation of leukocyte differentiation GO:1902105 159 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
action potential GO:0001508 78 0.029
actin cytoskeleton organization GO:0030036 220 0.029
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.029
positive regulation of growth GO:0045927 104 0.029
positive regulation of secretion by cell GO:1903532 114 0.029
Human
nucleotide catabolic process GO:0009166 217 0.029
heart contraction GO:0060047 93 0.029
regulation of hormone levels GO:0010817 211 0.029
erk1 and erk2 cascade GO:0070371 77 0.029
developmental maturation GO:0021700 193 0.029
skin development GO:0043588 220 0.028
oligodendrocyte differentiation GO:0048709 53 0.028
i kappab kinase nf kappab signaling GO:0007249 85 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
cation transmembrane transport GO:0098655 266 0.028
negative regulation of lymphocyte activation GO:0051250 91 0.028
cognition GO:0050890 149 0.028
adult locomotory behavior GO:0008344 91 0.028
detection of external stimulus GO:0009581 61 0.028
axonogenesis GO:0007409 274 0.027
canonical wnt signaling pathway GO:0060070 130 0.027
cell differentiation involved in embryonic placenta development GO:0060706 26 0.027
osteoclast differentiation GO:0030316 62 0.027
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.027
substantia nigra development GO:0021762 2 0.027
neuromuscular process controlling balance GO:0050885 59 0.027
glial cell differentiation GO:0010001 131 0.026
regulation of heart rate GO:0002027 36 0.026
regulation of hormone secretion GO:0046883 88 0.026
sensory perception of light stimulus GO:0050953 54 0.026
positive regulation of camp mediated signaling GO:0043950 3 0.026
adult behavior GO:0030534 135 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
ribose phosphate biosynthetic process GO:0046390 59 0.026
response to steroid hormone GO:0048545 56 0.026
bone resorption GO:0045453 38 0.026
second messenger mediated signaling GO:0019932 73 0.026
anatomical structure homeostasis GO:0060249 145 0.026
monoamine transport GO:0015844 33 0.025
regulation of t cell differentiation GO:0045580 83 0.025
cellular response to peptide hormone stimulus GO:0071375 92 0.025
neurotransmitter secretion GO:0007269 62 0.025
protein localization to plasma membrane GO:0072659 57 0.025
metanephros development GO:0001656 79 0.025
positive regulation of muscle tissue development GO:1901863 32 0.025
regulation of canonical wnt signaling pathway GO:0060828 82 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
Mouse
camp metabolic process GO:0046058 40 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
Mouse
establishment of organelle localization GO:0051656 122 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
response to peptide hormone GO:0043434 127 0.025
regulation of sodium ion transport GO:0002028 29 0.025
lymphocyte activation involved in immune response GO:0002285 93 0.025
cellular response to metal ion GO:0071248 31 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
inner ear morphogenesis GO:0042472 101 0.025
neuron death GO:0070997 154 0.025
gtp catabolic process GO:0006184 143 0.025
response to peptide GO:1901652 136 0.024
regulation of body fluid levels GO:0050878 162 0.024
Mouse
single organism nuclear import GO:1902593 95 0.024
positive regulation of nucleoside metabolic process GO:0045979 91 0.024
regulation of exocytosis GO:0017157 61 0.024
bone mineralization GO:0030282 54 0.024
Mouse
cyclic nucleotide biosynthetic process GO:0009190 44 0.024
defense response to virus GO:0051607 68 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
regulation of neuron differentiation GO:0045664 281 0.024
positive regulation of leukocyte proliferation GO:0070665 73 0.023
regulation of feeding behavior GO:0060259 3 0.023
cellular response to tumor necrosis factor GO:0071356 21 0.023
muscle tissue development GO:0060537 308 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
syncytium formation by plasma membrane fusion GO:0000768 42 0.023
neuron migration GO:0001764 122 0.023
nucleoside catabolic process GO:0009164 206 0.023
muscle hypertrophy GO:0014896 24 0.023
cyclic purine nucleotide metabolic process GO:0052652 43 0.023
monosaccharide metabolic process GO:0005996 106 0.023
sensory perception of pain GO:0019233 47 0.023
hair follicle development GO:0001942 85 0.023
muscle adaptation GO:0043500 39 0.023
cyclic nucleotide metabolic process GO:0009187 59 0.023
hexose metabolic process GO:0019318 98 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
regulation of cell projection organization GO:0031344 206 0.023
thymus development GO:0048538 41 0.023
negative regulation of synapse assembly GO:0051964 3 0.022
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.022
positive regulation of t cell activation GO:0050870 101 0.022
myotube differentiation GO:0014902 105 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
striated muscle contraction GO:0006941 45 0.022
peptide secretion GO:0002790 114 0.022
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.022
oligopeptide transmembrane transport GO:0035672 4 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
cellular response to inorganic substance GO:0071241 37 0.022
release of sequestered calcium ion into cytosol GO:0051209 42 0.022
peptide hormone secretion GO:0030072 109 0.022
positive regulation of urine volume GO:0035810 6 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
epidermis development GO:0008544 187 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.021
calcium ion transport into cytosol GO:0060402 48 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of interferon gamma production GO:0032649 57 0.021
positive regulation of transferase activity GO:0051347 167 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.021
tissue remodeling GO:0048771 102 0.021
cellular response to acid chemical GO:0071229 68 0.021
exocrine system development GO:0035272 45 0.021
myeloid cell homeostasis GO:0002262 114 0.021
regulation of voltage gated calcium channel activity GO:1901385 4 0.021
response to insulin GO:0032868 100 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
skin morphogenesis GO:0043589 38 0.021
positive regulation of lymphocyte proliferation GO:0050671 70 0.020
regulation of organelle organization GO:0033043 289 0.020
Mouse
lens development in camera type eye GO:0002088 62 0.020
regulation of erk1 and erk2 cascade GO:0070372 71 0.020
cardiac muscle cell contraction GO:0086003 7 0.020
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
actomyosin structure organization GO:0031032 56 0.020
epidermis morphogenesis GO:0048730 33 0.020
glucose transport GO:0015758 56 0.020
myeloid leukocyte activation GO:0002274 83 0.020
response to tumor necrosis factor GO:0034612 26 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
gastrin induced gastric acid secretion GO:0001698 1 0.020
glucose metabolic process GO:0006006 92 0.020
regulation of neurotransmitter levels GO:0001505 87 0.019
neuromuscular process GO:0050905 99 0.019
cell matrix adhesion GO:0007160 68 0.019
regulation of transcription involved in cell fate commitment GO:0060850 15 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.019
exocytosis GO:0006887 121 0.019
regulation of actin filament based process GO:0032970 99 0.019
Mouse
rho protein signal transduction GO:0007266 32 0.019
smooth muscle contraction GO:0006939 44 0.019
regulation of intracellular transport GO:0032386 159 0.019
epithelial cell morphogenesis GO:0003382 41 0.019
amide transport GO:0042886 138 0.019
regulation of mapk cascade GO:0043408 248 0.019
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
synapse organization GO:0050808 125 0.019
regulation of cellular response to growth factor stimulus GO:0090287 82 0.019
cellular response to temperature stimulus GO:0071502 2 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
muscle cell development GO:0055001 133 0.019
male sex determination GO:0030238 14 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
innate immune response GO:0045087 157 0.018
digestive system development GO:0055123 200 0.018
optic nerve structural organization GO:0021633 2 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
fatty acid metabolic process GO:0006631 121 0.018
positive regulation of protein transport GO:0051222 93 0.018
Human
nucleocytoplasmic transport GO:0006913 139 0.018
keratinization GO:0031424 9 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
chemotaxis GO:0006935 247 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
pallium development GO:0021543 120 0.018
organelle localization GO:0051640 179 0.018
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.018
detection of stimulus GO:0051606 84 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.017
insulin secretion GO:0030073 89 0.017
negative regulation of cell activation GO:0050866 111 0.017
regulation of fat cell proliferation GO:0070344 4 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of t cell proliferation GO:0042129 92 0.017
positive regulation of vasoconstriction GO:0045907 4 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.017
regulation of neurotransmitter secretion GO:0046928 29 0.017
keratinocyte differentiation GO:0030216 48 0.017
keratinocyte proliferation GO:0043616 21 0.017
transmission of nerve impulse GO:0019226 76 0.017
midgut development GO:0007494 4 0.017
histamine induced gastric acid secretion GO:0001697 1 0.017
protein targeting GO:0006605 143 0.017
negative regulation of multi organism process GO:0043901 68 0.017
regulation of notch signaling pathway GO:0008593 35 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
septum primum development GO:0003284 4 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
homeostasis of number of cells GO:0048872 210 0.017
kidney epithelium development GO:0072073 121 0.017
protein localization to organelle GO:0033365 185 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
Mouse
organic acid biosynthetic process GO:0016053 86 0.017
Mouse Rat
potassium ion transport GO:0006813 52 0.017
regulation of antimicrobial humoral response GO:0002759 3 0.017
regeneration GO:0031099 38 0.017
regulation of wound healing GO:0061041 40 0.017
tendon cell differentiation GO:0035990 4 0.017
hair cycle GO:0042633 90 0.017
divalent inorganic cation transport GO:0072511 178 0.016
nucleotide metabolic process GO:0009117 332 0.016
cell maturation GO:0048469 127 0.016
sensitization GO:0046960 2 0.016
response to oxidative stress GO:0006979 123 0.016
monovalent inorganic cation homeostasis GO:0055067 33 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
stem cell development GO:0048864 219 0.016
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.016
striated muscle adaptation GO:0014888 26 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
intestinal epithelial structure maintenance GO:0060729 4 0.016
retina development in camera type eye GO:0060041 119 0.016
actin filament based movement GO:0030048 23 0.016
interleukin 5 secretion GO:0072603 2 0.016
cardiac muscle contraction GO:0060048 32 0.016
regulation of gliogenesis GO:0014013 50 0.016
regulation of calcium ion transport into cytosol GO:0010522 31 0.016
membrane depolarization during sa node cell action potential GO:0086046 2 0.016
actin filament organization GO:0007015 113 0.016
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.016
multicellular organismal water homeostasis GO:0050891 23 0.016
Mouse
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.016
positive regulation of innate immune response GO:0045089 80 0.016
purine containing compound biosynthetic process GO:0072522 70 0.016
gliogenesis GO:0042063 141 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
skeletal muscle tissue regeneration GO:0043403 20 0.016
defense response to bacterium GO:0042742 119 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
multicellular organismal response to stress GO:0033555 62 0.016
bronchiole development GO:0060435 3 0.016
alpha beta t cell activation GO:0046631 91 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
activation of immune response GO:0002253 138 0.015
positive regulation of ion transport GO:0043270 65 0.015
regulation of ossification GO:0030278 112 0.015
regulation of action potential GO:0098900 4 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
mitral valve morphogenesis GO:0003183 4 0.015
response to growth factor GO:0070848 198 0.015
striated muscle cell development GO:0055002 125 0.015
positive regulation of striated muscle tissue development GO:0045844 31 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
Mouse
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.015
positive regulation of myeloid cell differentiation GO:0045639 43 0.015
embryonic skeletal system development GO:0048706 120 0.015
cellular response to amino acid stimulus GO:0071230 29 0.015
circadian rhythm GO:0007623 114 0.015
interferon gamma production GO:0032609 67 0.015
stem cell differentiation GO:0048863 268 0.015

Alox8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025