Mus musculus

0 known processes

Ap1s1

adaptor protein complex AP-1, sigma 1

(Aliases: AP19)

Ap1s1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of secretion by cell GO:1903530 249 0.142
carbohydrate metabolic process GO:0005975 230 0.127
ras protein signal transduction GO:0007265 77 0.127
gtp catabolic process GO:0006184 143 0.127
rho protein signal transduction GO:0007266 32 0.113
carbohydrate derivative biosynthetic process GO:1901137 183 0.096
cellular carbohydrate metabolic process GO:0044262 119 0.094
regulation of cellular ketone metabolic process GO:0010565 66 0.084
gtp metabolic process GO:0046039 144 0.078
small gtpase mediated signal transduction GO:0007264 97 0.077
cellular ketone metabolic process GO:0042180 84 0.063
positive regulation of cellular catabolic process GO:0031331 148 0.060
cytoplasmic transport GO:0016482 234 0.057
regulation of cell cycle GO:0051726 281 0.052
vesicle localization GO:0051648 86 0.051
regulation of secretion GO:0051046 274 0.051
protein maturation GO:0051604 176 0.048
cellular amino acid metabolic process GO:0006520 103 0.047
regulation of glucose metabolic process GO:0010906 60 0.047
regulation of cell projection organization GO:0031344 206 0.046
regulation of neuron differentiation GO:0045664 281 0.046
regulation of organelle organization GO:0033043 289 0.045
compound eye development GO:0048749 1 0.044
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
nucleotide metabolic process GO:0009117 332 0.043
synaptic transmission GO:0007268 329 0.042
regulation of cellular catabolic process GO:0031329 242 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
cellular response to nutrient levels GO:0031669 64 0.042
regulation of kinase activity GO:0043549 249 0.041
positive regulation of protein modification process GO:0031401 299 0.040
regulation of protein localization GO:0032880 231 0.040
epithelial tube morphogenesis GO:0060562 303 0.040
regulation of cell activation GO:0050865 289 0.040
positive regulation of secretion GO:0051047 130 0.040
protein localization to membrane GO:0072657 108 0.040
apoptotic signaling pathway GO:0097190 306 0.040
positive regulation of cell death GO:0010942 224 0.039
positive regulation of cell development GO:0010720 237 0.038
macroautophagy GO:0016236 21 0.037
mitochondrion organization GO:0007005 134 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
cellular homeostasis GO:0019725 240 0.037
glycoprotein biosynthetic process GO:0009101 89 0.037
activation of adenylate cyclase activity GO:0007190 4 0.036
developmental maturation GO:0021700 193 0.036
hexose catabolic process GO:0019320 3 0.036
guanosine containing compound metabolic process GO:1901068 144 0.034
positive regulation of ras gtpase activity GO:0032320 65 0.034
regulation of nucleotide catabolic process GO:0030811 122 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.033
striated muscle tissue development GO:0014706 293 0.033
glucose metabolic process GO:0006006 92 0.033
positive regulation of cytoskeleton organization GO:0051495 49 0.033
organelle localization GO:0051640 179 0.032
rac protein signal transduction GO:0016601 13 0.032
exocytosis GO:0006887 121 0.032
positive regulation of ruffle assembly GO:1900029 1 0.032
negative regulation of cell cycle GO:0045786 123 0.032
positive regulation of nervous system development GO:0051962 221 0.031
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.031
protein modification by small protein conjugation GO:0032446 187 0.030
response to nutrient levels GO:0031667 109 0.029
regulation of cell motility GO:2000145 236 0.029
purine containing compound metabolic process GO:0072521 311 0.029
cellular response to extracellular stimulus GO:0031668 81 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
cation transport GO:0006812 399 0.028
response to starvation GO:0042594 65 0.028
amine metabolic process GO:0009308 45 0.028
leukocyte proliferation GO:0070661 172 0.028
protein localization to organelle GO:0033365 185 0.028
regulation of cellular response to stress GO:0080135 159 0.027
protein catabolic process GO:0030163 221 0.027
guanosine containing compound catabolic process GO:1901069 144 0.027
microtubule based process GO:0007017 236 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
glycoprotein metabolic process GO:0009100 116 0.026
regulation of protein transport GO:0051223 163 0.026
membrane organization GO:0061024 245 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
macromolecule catabolic process GO:0009057 281 0.026
carbohydrate homeostasis GO:0033500 128 0.026
cell type specific apoptotic process GO:0097285 268 0.026
regulation of ion transport GO:0043269 215 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
cellular amine metabolic process GO:0044106 44 0.026
cellular protein complex assembly GO:0043623 116 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
cellular protein catabolic process GO:0044257 155 0.026
peptidyl amino acid modification GO:0018193 336 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
establishment of organelle localization GO:0051656 122 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
regulation of ras gtpase activity GO:0032318 88 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
regulation of cell cycle process GO:0010564 160 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
t cell activation GO:0042110 289 0.024
organophosphate catabolic process GO:0046434 232 0.024
hexose metabolic process GO:0019318 98 0.024
establishment of vesicle localization GO:0051650 81 0.024
skin development GO:0043588 220 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
epithelial cell proliferation GO:0050673 174 0.023
positive regulation of organelle organization GO:0010638 128 0.023
mapk cascade GO:0000165 281 0.023
carbohydrate biosynthetic process GO:0016051 74 0.023
macromolecule glycosylation GO:0043413 55 0.023
actin cytoskeleton organization GO:0030036 220 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
proteasomal protein catabolic process GO:0010498 98 0.022
mitotic cell cycle GO:0000278 195 0.022
regulation of cell migration GO:0030334 219 0.022
cellular response to starvation GO:0009267 57 0.022
positive regulation of gtpase activity GO:0043547 85 0.022
nucleotide biosynthetic process GO:0009165 78 0.022
glucose homeostasis GO:0042593 128 0.022
regulation of proteolysis GO:0030162 164 0.022
molting cycle GO:0042303 90 0.022
zymogen activation GO:0031638 41 0.022
negative regulation of neuron apoptotic process GO:0043524 92 0.022
negative regulation of molecular function GO:0044092 258 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of ras protein signal transduction GO:0046578 114 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of cellular component size GO:0032535 121 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
organic acid transport GO:0015849 101 0.021
forebrain development GO:0030900 302 0.021
carboxylic acid transport GO:0046942 100 0.021
positive regulation of nucleotide catabolic process GO:0030813 88 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
carbon catabolite activation of transcription GO:0045991 4 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
positive regulation of transferase activity GO:0051347 167 0.021
regulation of mapk cascade GO:0043408 248 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
myosin filament assembly GO:0031034 2 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
golgi vesicle transport GO:0048193 30 0.020
regulation of carbohydrate metabolic process GO:0006109 75 0.020
hormone secretion GO:0046879 128 0.020
organic anion transport GO:0015711 137 0.020
leukocyte differentiation GO:0002521 342 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of rho protein signal transduction GO:0035023 71 0.020
regulation of synaptic plasticity GO:0048167 87 0.020
purine nucleotide catabolic process GO:0006195 211 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
stem cell differentiation GO:0048863 268 0.019
transmembrane transport GO:0055085 412 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
maintenance of location GO:0051235 89 0.019
response to organonitrogen compound GO:0010243 246 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
myosin filament organization GO:0031033 3 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
smoothened signaling pathway GO:0007224 105 0.019
protein processing GO:0016485 163 0.019
response to extracellular stimulus GO:0009991 127 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
establishment of protein localization to organelle GO:0072594 118 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
sequestering of metal ion GO:0051238 19 0.018
oocyte axis specification GO:0007309 2 0.018
monosaccharide metabolic process GO:0005996 106 0.018
negative regulation of neuron death GO:1901215 98 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
germ cell development GO:0007281 185 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of transferase activity GO:0051338 263 0.018
calcium ion homeostasis GO:0055074 127 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
cell fate commitment GO:0045165 210 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
axonogenesis GO:0007409 274 0.018
Fly
g protein coupled receptor signaling pathway GO:0007186 243 0.018
intracellular protein transport GO:0006886 204 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
cellular chemical homeostasis GO:0055082 215 0.017
endocytosis GO:0006897 168 0.017
cell growth GO:0016049 130 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of response to wounding GO:1903034 189 0.017
lymphocyte proliferation GO:0046651 164 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
anion transport GO:0006820 177 0.017
striated muscle myosin thick filament assembly GO:0071688 1 0.017
regulation of neuron projection development GO:0010975 169 0.017
retrograde transport endosome to golgi GO:0042147 2 0.017
cellular lipid metabolic process GO:0044255 323 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
organelle assembly GO:0070925 177 0.017
positive regulation of mapk cascade GO:0043410 170 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
regulation of vacuole organization GO:0044088 4 0.016
telencephalon development GO:0021537 186 0.016
cellular glucose homeostasis GO:0001678 52 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
rap protein signal transduction GO:0032486 3 0.016
positive regulation of killing of cells of other organism GO:0051712 3 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
protein targeting GO:0006605 143 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
negative regulation of cell projection organization GO:0031345 56 0.016
regulation of anatomical structure size GO:0090066 178 0.015
actin filament organization GO:0007015 113 0.015
sequestering of calcium ion GO:0051208 18 0.015
heterocycle catabolic process GO:0046700 280 0.015
positive regulation of proteolysis GO:0045862 85 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
oocyte construction GO:0007308 2 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
regulation of intracellular transport GO:0032386 159 0.015
carbon catabolite regulation of transcription GO:0045990 4 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of cell size GO:0008361 72 0.015
cellular response to gamma radiation GO:0071480 4 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
regulation of actin filament based process GO:0032970 99 0.014
carbohydrate catabolic process GO:0016052 32 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
t cell proliferation GO:0042098 120 0.014
epidermis development GO:0008544 187 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
actin filament polymerization GO:0030041 44 0.014
oocyte development GO:0048599 33 0.014
muscle tissue development GO:0060537 308 0.014
regulation of exocytosis GO:0017157 61 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
wnt signaling pathway GO:0016055 188 0.014
nucleoside metabolic process GO:0009116 246 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
regulation of peptide transport GO:0090087 91 0.014
aromatic compound catabolic process GO:0019439 286 0.014
peptide hormone secretion GO:0030072 109 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
regulation of peptidase activity GO:0052547 96 0.014
positive regulation of rap gtpase activity GO:0032854 3 0.014
muscle cell differentiation GO:0042692 261 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
alcohol metabolic process GO:0006066 116 0.013
blood circulation GO:0008015 195 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
organelle fission GO:0048285 170 0.013
positive regulation of necrotic cell death GO:0010940 1 0.013
positive regulation of transcription by galactose GO:0000411 1 0.013
myeloid cell differentiation GO:0030099 233 0.013
divalent metal ion transport GO:0070838 172 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of peptide secretion GO:0002791 77 0.013
negative regulation of cell development GO:0010721 169 0.013
positive regulation of cell motility GO:2000147 116 0.013
cellular ion homeostasis GO:0006873 165 0.013
b cell activation GO:0042113 161 0.013
regulation of macroautophagy GO:0016241 12 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
cell substrate adhesion GO:0031589 130 0.013
cell maturation GO:0048469 127 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
oxidation reduction process GO:0055114 342 0.012
learning or memory GO:0007611 148 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
response to light stimulus GO:0009416 135 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
monosaccharide transport GO:0015749 58 0.012
mesenchymal cell differentiation GO:0048762 107 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of homeostatic process GO:0032844 182 0.012
nuclear transport GO:0051169 139 0.012
vacuole organization GO:0007033 38 0.012
regulation of nucleotide biosynthetic process GO:0030808 34 0.012
neural tube development GO:0021915 160 0.012
homeostasis of number of cells GO:0048872 210 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
male gamete generation GO:0048232 285 0.012
jnk cascade GO:0007254 72 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
response to iron ion GO:0010039 4 0.012
peptide secretion GO:0002790 114 0.012
rna interference GO:0016246 2 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
modification by symbiont of host morphology or physiology GO:0044003 4 0.012
cellular response to lipid GO:0071396 145 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
protein secretion GO:0009306 111 0.012
microtubule based movement GO:0007018 84 0.012
positive regulation of epithelial cell proliferation GO:0050679 68 0.012
regulation of rho gtpase activity GO:0032319 58 0.011
cell communication by chemical coupling GO:0010643 2 0.011
wound healing GO:0042060 157 0.011
skeletal muscle organ development GO:0060538 163 0.011
regulation of hormone levels GO:0010817 211 0.011
camp biosynthetic process GO:0006171 31 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
covalent chromatin modification GO:0016569 163 0.011
response to mineralocorticoid GO:0051385 1 0.011
positive regulation of response to wounding GO:1903036 66 0.011
response to organic cyclic compound GO:0014070 198 0.011
negative regulation of cell motility GO:2000146 61 0.011
protein glycosylation GO:0006486 55 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
negative regulation of cell migration GO:0030336 59 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
melanosome localization GO:0032400 12 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
female gamete generation GO:0007292 74 0.011
inflammatory response GO:0006954 244 0.011
regulation of wound healing GO:0061041 40 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
cell cycle arrest GO:0007050 37 0.011
gene silencing GO:0016458 38 0.011
neuron death GO:0070997 154 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.011
stress activated mapk cascade GO:0051403 80 0.011
second messenger mediated signaling GO:0019932 73 0.011
regulation of carbohydrate biosynthetic process GO:0043255 40 0.011
localization within membrane GO:0051668 4 0.011
cyclic nucleotide biosynthetic process GO:0009190 44 0.011
positive regulation of kinase activity GO:0033674 155 0.010
lymphocyte differentiation GO:0030098 242 0.010
stem cell development GO:0048864 219 0.010
cation transmembrane transport GO:0098655 266 0.010
epithelial cell migration GO:0010631 63 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
regulation of protein processing GO:0070613 96 0.010
gland development GO:0048732 330 0.010
regulation of protein secretion GO:0050708 82 0.010
response to inorganic substance GO:0010035 96 0.010
lipid biosynthetic process GO:0008610 179 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
neuron projection guidance GO:0097485 141 0.010
Fly
amide transport GO:0042886 138 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
photoreceptor cell morphogenesis GO:0008594 3 0.010

Ap1s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.042
colon cancer DOID:219 0 0.020
large intestine cancer DOID:5672 0 0.020
colorectal cancer DOID:9256 0 0.020
gastrointestinal system cancer DOID:3119 0 0.020
intestinal cancer DOID:10155 0 0.020
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015