Mus musculus

0 known processes

Ap2s1

adaptor-related protein complex 2, sigma 1 subunit

(Aliases: AI043088,MGC62945)

Ap2s1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of ruffle assembly GO:1900029 1 0.427
regulation of secretion GO:0051046 274 0.191
actin cytoskeleton organization GO:0030036 220 0.175
purine nucleoside metabolic process GO:0042278 241 0.133
organelle assembly GO:0070925 177 0.124
vesicle localization GO:0051648 86 0.106
golgi to endosome transport GO:0006895 3 0.106
ribonucleoside metabolic process GO:0009119 245 0.104
organelle localization GO:0051640 179 0.101
tissue migration GO:0090130 68 0.101
regulation of hormone levels GO:0010817 211 0.098
cellular protein complex assembly GO:0043623 116 0.098
cilium assembly GO:0042384 81 0.096
nucleotide metabolic process GO:0009117 332 0.095
nucleobase containing small molecule metabolic process GO:0055086 352 0.089
actin filament organization GO:0007015 113 0.086
microtubule based process GO:0007017 236 0.083
epithelial tube morphogenesis GO:0060562 303 0.078
purine ribonucleotide metabolic process GO:0009150 290 0.076
regulation of cell migration GO:0030334 219 0.074
ameboidal type cell migration GO:0001667 128 0.073
positive regulation of cell motility GO:2000147 116 0.071
nucleoside phosphate metabolic process GO:0006753 338 0.070
positive regulation of necrotic cell death GO:0010940 1 0.068
positive regulation of mapk cascade GO:0043410 170 0.068
regulation of secretion by cell GO:1903530 249 0.067
organonitrogen compound catabolic process GO:1901565 264 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.064
positive regulation of cell development GO:0010720 237 0.063
glycosyl compound metabolic process GO:1901657 246 0.062
purine containing compound metabolic process GO:0072521 311 0.062
positive regulation of transferase activity GO:0051347 167 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
rap protein signal transduction GO:0032486 3 0.060
pigment granule localization GO:0051875 13 0.060
peptide transport GO:0015833 133 0.056
regulation of organelle organization GO:0033043 289 0.056
striated muscle cell development GO:0055002 125 0.056
establishment of vesicle localization GO:0051650 81 0.055
positive regulation of kinase activity GO:0033674 155 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
hexose catabolic process GO:0019320 3 0.053
carbohydrate homeostasis GO:0033500 128 0.052
purine nucleotide metabolic process GO:0006163 302 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
ribose phosphate metabolic process GO:0019693 291 0.049
regulation of establishment of protein localization GO:0070201 181 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.047
positive regulation of cellular component biogenesis GO:0044089 94 0.046
epithelial cell migration GO:0010631 63 0.046
cellular component assembly involved in morphogenesis GO:0010927 139 0.046
single organism nuclear import GO:1902593 95 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.044
membrane organization GO:0061024 245 0.044
cellular response to cytokine stimulus GO:0071345 189 0.043
glucose catabolic process GO:0006007 3 0.043
epithelium migration GO:0090132 63 0.043
regulation of cell motility GO:2000145 236 0.043
organelle fission GO:0048285 170 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
cilium morphogenesis GO:0060271 102 0.042
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.041
protein localization to membrane GO:0072657 108 0.039
organophosphate catabolic process GO:0046434 232 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
establishment of organelle localization GO:0051656 122 0.038
regulation of kinase activity GO:0043549 249 0.038
positive regulation of protein transport GO:0051222 93 0.037
regionalization GO:0003002 337 0.035
myosin filament organization GO:0031033 3 0.035
carbohydrate metabolic process GO:0005975 230 0.034
zymogen activation GO:0031638 41 0.033
purine containing compound biosynthetic process GO:0072522 70 0.033
muscle tissue development GO:0060537 308 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
adiponectin activated signaling pathway GO:0033211 4 0.032
negative regulation of neuron death GO:1901215 98 0.032
positive regulation of secretion GO:0051047 130 0.031
regulation of hydrolase activity GO:0051336 246 0.031
positive regulation of cell migration GO:0030335 109 0.031
heterocycle catabolic process GO:0046700 280 0.030
positive regulation of cell activation GO:0050867 158 0.030
activation of adenylate cyclase activity GO:0007190 4 0.030
macroautophagy GO:0016236 21 0.029
pigmentation GO:0043473 71 0.029
b cell activation GO:0042113 161 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
spermatogenesis GO:0007283 284 0.029
negative regulation of cell motility GO:2000146 61 0.029
germ cell development GO:0007281 185 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
cytokine mediated signaling pathway GO:0019221 115 0.028
glucose homeostasis GO:0042593 128 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.027
synaptic transmission GO:0007268 329 0.027
epidermis development GO:0008544 187 0.027
positive regulation of cell projection organization GO:0031346 95 0.027
actin polymerization or depolymerization GO:0008154 54 0.027
regulation of cell cycle GO:0051726 281 0.027
arp2 3 complex mediated actin nucleation GO:0034314 3 0.026
regulation of cell projection organization GO:0031344 206 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
neuron death GO:0070997 154 0.025
cellular response to hexose stimulus GO:0071331 47 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
regulation of protein heterodimerization activity GO:0043497 2 0.025
peptide hormone secretion GO:0030072 109 0.025
muscle cell development GO:0055001 133 0.025
branching morphogenesis of an epithelial tube GO:0048754 159 0.025
positive regulation of cytoskeleton organization GO:0051495 49 0.025
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.025
muscle cell differentiation GO:0042692 261 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
cellular response to glucose stimulus GO:0071333 45 0.024
t cell activation GO:0042110 289 0.024
exocytosis GO:0006887 121 0.024
striated muscle tissue development GO:0014706 293 0.024
mitotic cell cycle process GO:1903047 159 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
cell cycle checkpoint GO:0000075 47 0.024
male gamete generation GO:0048232 285 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
regulation of cell activation GO:0050865 289 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
aromatic compound catabolic process GO:0019439 286 0.022
positive regulation of hormone secretion GO:0046887 38 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
skin development GO:0043588 220 0.022
negative regulation of cell migration GO:0030336 59 0.022
mitochondrion organization GO:0007005 134 0.022
peptide secretion GO:0002790 114 0.022
amine metabolic process GO:0009308 45 0.022
protein localization to organelle GO:0033365 185 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
regulation of neuron death GO:1901214 134 0.021
negative regulation of cell cycle GO:0045786 123 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
positive regulation of actin filament polymerization GO:0030838 26 0.021
endocytosis GO:0006897 168 0.021
Fly
oocyte construction GO:0007308 2 0.021
rna interference GO:0016246 2 0.021
multicellular organism growth GO:0035264 161 0.021
intracellular protein transport GO:0006886 204 0.021
leukocyte proliferation GO:0070661 172 0.021
regulation of glucose metabolic process GO:0010906 60 0.021
regulation of transposition GO:0010528 2 0.020
cellular ketone metabolic process GO:0042180 84 0.020
gene silencing by rna GO:0031047 19 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
microtubule based movement GO:0007018 84 0.020
skeletal muscle organ development GO:0060538 163 0.020
multi organism behavior GO:0051705 62 0.020
positive regulation of protein modification process GO:0031401 299 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
regulation of protein transport GO:0051223 163 0.020
positive regulation of organelle organization GO:0010638 128 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
cell type specific apoptotic process GO:0097285 268 0.019
positive regulation of map kinase activity GO:0043406 84 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
striated muscle myosin thick filament assembly GO:0071688 1 0.019
cellular amine metabolic process GO:0044106 44 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.019
regulation of t cell activation GO:0050863 170 0.019
protein targeting GO:0006605 143 0.018
cellular response to lipid GO:0071396 145 0.018
myosin filament assembly GO:0031034 2 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
regulation of clathrin mediated endocytosis GO:2000369 4 0.018
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.018
regulation of actin cytoskeleton organization GO:0032956 84 0.018
gtp catabolic process GO:0006184 143 0.018
regulation of cellular component size GO:0032535 121 0.018
t cell proliferation GO:0042098 120 0.018
ras protein signal transduction GO:0007265 77 0.018
golgi vesicle transport GO:0048193 30 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
mapk cascade GO:0000165 281 0.018
cell fate commitment GO:0045165 210 0.018
regulation of epithelial cell migration GO:0010632 35 0.018
myotube differentiation GO:0014902 105 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
compound eye development GO:0048749 1 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of neuron differentiation GO:0045664 281 0.017
lymphocyte proliferation GO:0046651 164 0.017
positive regulation of cell death GO:0010942 224 0.017
nuclear import GO:0051170 95 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
protein localization to nonmotile primary cilium GO:0097499 1 0.017
regulation of peptidase activity GO:0052547 96 0.017
nitrogen compound transport GO:0071705 271 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
neural tube development GO:0021915 160 0.016
virion assembly GO:0019068 1 0.016
cell maturation GO:0048469 127 0.016
apoptotic signaling pathway GO:0097190 306 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
viral process GO:0016032 41 0.016
regulation of necrotic cell death GO:0010939 13 0.016
cell division GO:0051301 120 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
positive regulation of protein complex assembly GO:0031334 45 0.016
protein catabolic process GO:0030163 221 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
positive regulation of protein secretion GO:0050714 52 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
melanosome transport GO:0032402 11 0.015
positive regulation of membrane potential GO:0045838 15 0.015
regulation of homeostatic process GO:0032844 182 0.015
tissue homeostasis GO:0001894 115 0.015
protein polymerization GO:0051258 57 0.015
nucleotide catabolic process GO:0009166 217 0.015
carbon catabolite regulation of transcription GO:0045990 4 0.015
positive regulation of stress activated mapk cascade GO:0032874 48 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
actin filament polymerization GO:0030041 44 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.015
negative regulation of epithelial cell migration GO:0010633 9 0.015
protein localization to plasma membrane GO:0072659 57 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
regulation of endocytosis GO:0030100 69 0.015
lung development GO:0030324 164 0.015
cellular response to monosaccharide stimulus GO:0071326 47 0.014
retina development in camera type eye GO:0060041 119 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
hexose metabolic process GO:0019318 98 0.014
mitochondrial fission GO:0000266 12 0.014
carbohydrate catabolic process GO:0016052 32 0.014
regulation of protein localization GO:0032880 231 0.014
spermatid development GO:0007286 108 0.014
respiratory system development GO:0060541 190 0.014
endothelial cell migration GO:0043542 44 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
genitalia development GO:0048806 37 0.014
regulation of peptide secretion GO:0002791 77 0.014
kidney development GO:0001822 213 0.014
negative regulation of cell development GO:0010721 169 0.014
digestive system development GO:0055123 200 0.014
epithelial cell development GO:0002064 159 0.014
receptor mediated endocytosis GO:0006898 51 0.014
mesenchymal cell differentiation GO:0048762 107 0.014
regulation of transferase activity GO:0051338 263 0.014
regulation of cellular catabolic process GO:0031329 242 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
carbon catabolite activation of transcription GO:0045991 4 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
protein import into nucleus GO:0006606 95 0.013
macromolecule catabolic process GO:0009057 281 0.013
cytoplasmic transport GO:0016482 234 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
positive regulation of epithelial cell proliferation GO:0050679 68 0.013
actomyosin structure organization GO:0031032 56 0.013
substrate adhesion dependent cell spreading GO:0034446 30 0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.013
cellular glucose homeostasis GO:0001678 52 0.013
calcium ion homeostasis GO:0055074 127 0.013
vesicle organization GO:0016050 60 0.013
protein maturation GO:0051604 176 0.013
organ or tissue specific immune response GO:0002251 13 0.013
mitotic cell cycle GO:0000278 195 0.013
response to growth factor GO:0070848 198 0.013
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.013
cellular response to nerve growth factor stimulus GO:1990090 3 0.013
adult behavior GO:0030534 135 0.013
signal transduction in absence of ligand GO:0038034 55 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of cellular response to stress GO:0080135 159 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
cellular homeostasis GO:0019725 240 0.013
reproductive behavior GO:0019098 32 0.013
negative regulation of stress fiber assembly GO:0051497 4 0.013
regulation of cell killing GO:0031341 40 0.013
regulation of t cell proliferation GO:0042129 92 0.012
nucleoside metabolic process GO:0009116 246 0.012
meiotic cell cycle process GO:1903046 77 0.012
negative regulation of organelle organization GO:0010639 90 0.012
single organism cell adhesion GO:0098602 156 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
oocyte development GO:0048599 33 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.012
regulation of muscle tissue development GO:1901861 97 0.012
camera type eye development GO:0043010 266 0.012
regulation of proteolysis GO:0030162 164 0.012
regulation of neuronal synaptic plasticity GO:0048168 30 0.012
second messenger mediated signaling GO:0019932 73 0.012
regulation of chromatin modification GO:1903308 57 0.012
leukocyte migration GO:0050900 124 0.012
negative regulation of endothelial cell migration GO:0010596 4 0.012
regulation of defense response GO:0031347 233 0.012
positive regulation of transcription by galactose GO:0000411 1 0.012
maintenance of location GO:0051235 89 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
renal system development GO:0072001 225 0.012
positive regulation of peptide secretion GO:0002793 33 0.012
protein import GO:0017038 101 0.012
response to nerve growth factor GO:1990089 3 0.012
telencephalon development GO:0021537 186 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
negative regulation of cell projection organization GO:0031345 56 0.011
disruption by symbiont of host cell GO:0044004 2 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
cation transport GO:0006812 399 0.011
chromatin modification GO:0016568 187 0.011
amide transport GO:0042886 138 0.011
oocyte differentiation GO:0009994 35 0.011
respiratory tube development GO:0030323 167 0.011
glycoprotein metabolic process GO:0009100 116 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
development of primary sexual characteristics GO:0045137 143 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
nucleoside catabolic process GO:0009164 206 0.011
gtp metabolic process GO:0046039 144 0.011
positive regulation of nervous system development GO:0051962 221 0.011
cell communication by chemical coupling GO:0010643 2 0.011
type b pancreatic cell proliferation GO:0044342 10 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
positive regulation of activin receptor signaling pathway GO:0032927 3 0.011
mucosal immune response GO:0002385 13 0.011
cellular response to cadmium ion GO:0071276 3 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
regulation of response to drug GO:2001023 2 0.011
purine nucleoside catabolic process GO:0006152 205 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
interspecies interaction between organisms GO:0044419 83 0.010
protein neddylation GO:0045116 1 0.010
morphogenesis of an endothelium GO:0003159 2 0.010
myeloid cell differentiation GO:0030099 233 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
gonad development GO:0008406 141 0.010
blood vessel morphogenesis GO:0048514 285 0.010
cytoskeleton dependent intracellular transport GO:0030705 50 0.010
developmental maturation GO:0021700 193 0.010
regulation of hormone secretion GO:0046883 88 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
sensory system development GO:0048880 3 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
positive regulation of peptide hormone secretion GO:0090277 31 0.010
bmp signaling pathway GO:0030509 93 0.010
cellular lipid metabolic process GO:0044255 323 0.010
mitotic cytokinesis GO:0000281 4 0.010
rho protein signal transduction GO:0007266 32 0.010
melanosome organization GO:0032438 8 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010

Ap2s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
endocrine gland cancer DOID:170 0 0.024
nervous system disease DOID:863 0 0.014
disease of anatomical entity DOID:7 0 0.014
central nervous system disease DOID:331 0 0.014