Mus musculus

125 known processes

Aplp2

amyloid beta (A4) precursor-like protein 2

(Aliases: APLP-2,AI790698)

Aplp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
copper ion homeostasis GO:0055070 9 0.997
mrna 3 end processing GO:0031124 16 0.995
Mouse
inositol phosphate mediated signaling GO:0048016 13 0.969
rna 3 end processing GO:0031123 20 0.915
Mouse
cell adhesion GO:0007155 329 0.820
cellular copper ion homeostasis GO:0006878 8 0.745
mrna polyadenylation GO:0006378 5 0.719
Mouse
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.707
Mouse
neuron apoptotic process GO:0051402 142 0.599
Mouse
chemotaxis GO:0006935 247 0.590
Mouse
microtubule based transport GO:0010970 50 0.580
Mouse
sterol metabolic process GO:0016125 58 0.425
developmental maturation GO:0021700 193 0.409
Mouse
intracellular mrna localization GO:0008298 4 0.404
regulation of protein kinase activity GO:0045859 232 0.384
apoptotic signaling pathway GO:0097190 306 0.374
regulation of kinase activity GO:0043549 249 0.371
cellular amino acid metabolic process GO:0006520 103 0.359
posttranscriptional regulation of gene expression GO:0010608 155 0.346
Mouse
cognition GO:0050890 149 0.346
Mouse Fly
negative regulation of neuron death GO:1901215 98 0.345
Fly
organic hydroxy compound metabolic process GO:1901615 203 0.342
transmembrane transport GO:0055085 412 0.324
neuron projection guidance GO:0097485 141 0.314
Mouse
calcineurin nfat signaling cascade GO:0033173 8 0.309
negative regulation of molecular function GO:0044092 258 0.308
ion transmembrane transport GO:0034220 361 0.297
peripheral nervous system development GO:0007422 53 0.295
Fly
positive regulation of cell death GO:0010942 224 0.286
cell recognition GO:0008037 83 0.285
Mouse
positive regulation of neuron projection development GO:0010976 79 0.274
pole plasm assembly GO:0007315 2 0.258
negative regulation of protein metabolic process GO:0051248 282 0.254
cation transport GO:0006812 399 0.250
regulation of neuron projection development GO:0010975 169 0.242
regulation of protein serine threonine kinase activity GO:0071900 157 0.221
cation homeostasis GO:0055080 212 0.221
purine nucleoside metabolic process GO:0042278 241 0.218
regulation of cellular component size GO:0032535 121 0.217
glycosyl compound catabolic process GO:1901658 206 0.214
acetylcholine transport GO:0015870 2 0.212
oocyte axis specification GO:0007309 2 0.206
actin cytoskeleton reorganization GO:0031532 21 0.206
response to radiation GO:0009314 165 0.206
Mouse
cellularization GO:0007349 1 0.206
axonogenesis GO:0007409 274 0.202
Mouse
learning or memory GO:0007611 148 0.200
Mouse Fly
cellular metal ion homeostasis GO:0006875 151 0.198
translation GO:0006412 93 0.197
Mouse
negative regulation of cell proliferation GO:0008285 296 0.196
regulation of cellular ketone metabolic process GO:0010565 66 0.192
anion transport GO:0006820 177 0.191
endomembrane system organization GO:0010256 147 0.190
cellular ketone metabolic process GO:0042180 84 0.190
engulfment of apoptotic cell GO:0043652 3 0.189
response to growth factor GO:0070848 198 0.180
divalent inorganic cation homeostasis GO:0072507 138 0.179
Mouse
regulation of cellular response to stress GO:0080135 159 0.176
nucleobase containing small molecule metabolic process GO:0055086 352 0.172
purine nucleotide metabolic process GO:0006163 302 0.172
heterocycle catabolic process GO:0046700 280 0.171
forebrain development GO:0030900 302 0.169
developmental cell growth GO:0048588 84 0.169
Mouse
cellular amine metabolic process GO:0044106 44 0.166
regulation of cell projection organization GO:0031344 206 0.166
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.162
positive regulation of apoptotic signaling pathway GO:2001235 95 0.160
cellular response to dna damage stimulus GO:0006974 207 0.160
regulation of transmembrane transport GO:0034762 128 0.159
interleukin 17 production GO:0032620 11 0.158
regulation of protein tyrosine kinase activity GO:0061097 17 0.154
regulation of protein localization GO:0032880 231 0.154
regulation of cellular component biogenesis GO:0044087 181 0.153
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.152
mapk cascade GO:0000165 281 0.151
negative regulation of activated t cell proliferation GO:0046007 7 0.150
regulation of endocytosis GO:0030100 69 0.149
cell junction maintenance GO:0034331 4 0.148
locomotory behavior GO:0007626 195 0.147
cellular response to oxidative stress GO:0034599 76 0.147
metal ion homeostasis GO:0055065 189 0.147
mrna processing GO:0006397 63 0.145
Mouse
amine metabolic process GO:0009308 45 0.140
telencephalon development GO:0021537 186 0.139
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.138
negative regulation of phosphate metabolic process GO:0045936 184 0.138
reproductive behavior GO:0019098 32 0.137
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.133
protein localization to membrane GO:0072657 108 0.132
regulation of peptidase activity GO:0052547 96 0.129
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.125
cellular response to growth factor stimulus GO:0071363 197 0.124
multicellular organism growth GO:0035264 161 0.124
Mouse Worm
organic cyclic compound catabolic process GO:1901361 295 0.123
adherens junction maintenance GO:0034334 1 0.123
extracellular structure organization GO:0043062 148 0.122
regulation of protein binding GO:0043393 60 0.121
regulation of cell cycle GO:0051726 281 0.121
Mouse
positive regulation of cell projection organization GO:0031346 95 0.120
dendrite development GO:0016358 115 0.120
Mouse
neuron death GO:0070997 154 0.119
Mouse Fly
guanosine containing compound metabolic process GO:1901068 144 0.119
body morphogenesis GO:0010171 45 0.117
Worm
regulation of cell migration GO:0030334 219 0.116
cytokine production GO:0001816 319 0.116
response to oxidative stress GO:0006979 123 0.115
Mouse
nucleotide metabolic process GO:0009117 332 0.115
regulation of ion transport GO:0043269 215 0.115
sensory perception GO:0007600 245 0.113
regulation of protein stability GO:0031647 52 0.112
regulation of neuron differentiation GO:0045664 281 0.111
Mouse
transition metal ion homeostasis GO:0055076 54 0.110
purine containing compound metabolic process GO:0072521 311 0.109
cation transmembrane transport GO:0098655 266 0.109
regulation of mapk cascade GO:0043408 248 0.109
cell maturation GO:0048469 127 0.108
Mouse
leukocyte migration GO:0050900 124 0.107
regulation of erbb signaling pathway GO:1901184 16 0.107
positive regulation of programmed cell death GO:0043068 218 0.107
glial cell differentiation GO:0010001 131 0.104
neuron recognition GO:0008038 25 0.104
Mouse
positive regulation of ion transport GO:0043270 65 0.102
multi organism behavior GO:0051705 62 0.102
regulation of transferase activity GO:0051338 263 0.101
ribonucleoside catabolic process GO:0042454 206 0.101
regulation of cellular amino acid metabolic process GO:0006521 5 0.098
nucleoside triphosphate catabolic process GO:0009143 205 0.097
germ cell development GO:0007281 185 0.097
oocyte construction GO:0007308 2 0.096
central nervous system neuron differentiation GO:0021953 162 0.095
cell growth GO:0016049 130 0.095
Mouse
oocyte anterior posterior axis specification GO:0007314 2 0.095
myeloid cell differentiation GO:0030099 233 0.094
regulation of ion transmembrane transport GO:0034765 119 0.094
regulation of membrane potential GO:0042391 192 0.094
purine nucleoside triphosphate catabolic process GO:0009146 203 0.092
protein modification by small protein conjugation GO:0032446 187 0.092
ribose phosphate metabolic process GO:0019693 291 0.090
endocytosis GO:0006897 168 0.088
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.088
cellular protein complex assembly GO:0043623 116 0.088
regulation of calcineurin nfat signaling cascade GO:0070884 5 0.086
regulation of cell motility GO:2000145 236 0.086
small gtpase mediated signal transduction GO:0007264 97 0.086
rho protein signal transduction GO:0007266 32 0.085
carboxylic acid biosynthetic process GO:0046394 86 0.084
single organism cell adhesion GO:0098602 156 0.083
positive regulation of cytokine production GO:0001819 174 0.082
membrane organization GO:0061024 245 0.082
purine containing compound catabolic process GO:0072523 213 0.082
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.081
regulation of t cell activation GO:0050863 170 0.081
nucleoside metabolic process GO:0009116 246 0.081
purine ribonucleoside metabolic process GO:0046128 241 0.081
negative regulation of cellular amide metabolic process GO:0034249 4 0.081
regulation of cell adhesion GO:0030155 154 0.079
regulation of map kinase activity GO:0043405 120 0.079
protein maturation GO:0051604 176 0.078
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.078
carbohydrate derivative catabolic process GO:1901136 231 0.078
ribonucleotide metabolic process GO:0009259 291 0.077
guanosine containing compound catabolic process GO:1901069 144 0.077
cell junction assembly GO:0034329 52 0.077
cellular calcium ion homeostasis GO:0006874 119 0.076
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.075
regulation of protein complex assembly GO:0043254 83 0.074
protein localization to plasma membrane GO:0072659 57 0.073
nucleoside catabolic process GO:0009164 206 0.072
extracellular matrix organization GO:0030198 147 0.071
regulation of hydrolase activity GO:0051336 246 0.070
inorganic ion transmembrane transport GO:0098660 234 0.070
g protein coupled receptor signaling pathway GO:0007186 243 0.069
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.069
regulation of binding GO:0051098 111 0.068
negative regulation of cellular component organization GO:0051129 194 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.067
cellular ion homeostasis GO:0006873 165 0.067
ribonucleoside metabolic process GO:0009119 245 0.066
mating behavior GO:0007617 20 0.066
ensheathment of neurons GO:0007272 76 0.066
negative regulation of t cell proliferation GO:0042130 38 0.065
ribonucleoside triphosphate metabolic process GO:0009199 220 0.065
maternal determination of anterior posterior axis embryo GO:0008358 2 0.065
positive regulation of cell adhesion GO:0045785 80 0.064
feeding behavior GO:0007631 62 0.064
regulation of protein processing GO:0070613 96 0.064
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.064
cellular amide metabolic process GO:0043603 58 0.063
mrna metabolic process GO:0016071 84 0.063
Mouse
regulation of neuron death GO:1901214 134 0.063
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.062
ossification GO:0001503 216 0.061
protein oligomerization GO:0051259 67 0.061
regulation of cellular catabolic process GO:0031329 242 0.061
positive regulation of necrotic cell death GO:0010940 1 0.061
adult locomotory behavior GO:0008344 91 0.061
Mouse
cell cell junction organization GO:0045216 72 0.061
neuron migration GO:0001764 122 0.060
determination of digestive tract left right asymmetry GO:0071907 1 0.060
negative regulation of phosphorus metabolic process GO:0010563 184 0.060
positive regulation of cell cycle GO:0045787 92 0.059
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.058
molting cycle GO:0042303 90 0.058
Worm
glycoprotein metabolic process GO:0009100 116 0.057
calcium ion transmembrane transport GO:0070588 85 0.057
cell type specific apoptotic process GO:0097285 268 0.057
Mouse
skeletal system development GO:0001501 356 0.056
cellular divalent inorganic cation homeostasis GO:0072503 127 0.056
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.056
regulation of cell substrate adhesion GO:0010810 73 0.055
hindbrain development GO:0030902 128 0.055
purine ribonucleoside catabolic process GO:0046130 205 0.055
purine nucleoside triphosphate metabolic process GO:0009144 226 0.055
positive regulation of cellular catabolic process GO:0031331 148 0.055
sodium ion transport GO:0006814 73 0.055
regulation of endopeptidase activity GO:0052548 89 0.055
regulation of beta amyloid clearance GO:1900221 1 0.054
single organismal cell cell adhesion GO:0016337 131 0.054
peptidyl tyrosine phosphorylation GO:0018108 143 0.054
response to peptide GO:1901652 136 0.054
response to light stimulus GO:0009416 135 0.054
Mouse
nucleotide catabolic process GO:0009166 217 0.054
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.054
Mouse
cellular lipid metabolic process GO:0044255 323 0.054
membrane invagination GO:0010324 17 0.053
glycosyl compound metabolic process GO:1901657 246 0.053
gland development GO:0048732 330 0.052
purine nucleotide catabolic process GO:0006195 211 0.052
gtp metabolic process GO:0046039 144 0.052
phospholipid metabolic process GO:0006644 87 0.052
nucleoside monophosphate metabolic process GO:0009123 85 0.052
multi organism reproductive behavior GO:0044705 29 0.052
bone development GO:0060348 120 0.051
axon guidance GO:0007411 141 0.051
Mouse
epidermal growth factor receptor signaling pathway GO:0007173 28 0.051
forebrain cell migration GO:0021885 58 0.051
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.051
extrinsic apoptotic signaling pathway GO:0097191 126 0.051
blood vessel morphogenesis GO:0048514 285 0.051
apical junction assembly GO:0043297 15 0.051
telencephalon cell migration GO:0022029 55 0.051
positive regulation of proteolysis GO:0045862 85 0.050
wnt signaling pathway GO:0016055 188 0.050
myelination GO:0042552 74 0.050
regulation of calcium mediated signaling GO:0050848 19 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
regulation of cell cycle process GO:0010564 160 0.050
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.050
glycerophospholipid metabolic process GO:0006650 71 0.050
plasma membrane organization GO:0007009 90 0.049
negative regulation of protein phosphorylation GO:0001933 126 0.049
fatty acid biosynthetic process GO:0006633 41 0.049
associative learning GO:0008306 61 0.048
Mouse
inclusion body assembly GO:0070841 3 0.048
purine nucleoside catabolic process GO:0006152 205 0.048
glutamate receptor signaling pathway GO:0007215 35 0.048
Mouse
organelle assembly GO:0070925 177 0.047
rna processing GO:0006396 105 0.047
Mouse
cellular homeostasis GO:0019725 240 0.047
ras protein signal transduction GO:0007265 77 0.047
actin polymerization or depolymerization GO:0008154 54 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.046
regulation of response to oxidative stress GO:1902882 19 0.046
cellular response to arsenic containing substance GO:0071243 4 0.046
negative regulation of cell development GO:0010721 169 0.045
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.045
regulation of response to wounding GO:1903034 189 0.045
regulation of defense response GO:0031347 233 0.045
regulation of anion transport GO:0044070 27 0.045
positive regulation of macroautophagy GO:0016239 3 0.044
positive regulation of nervous system development GO:0051962 221 0.044
peptide metabolic process GO:0006518 46 0.044
macromolecule catabolic process GO:0009057 281 0.044
regulation of cytokine production GO:0001817 266 0.044
protein catabolic process GO:0030163 221 0.044
regulation of proteolysis GO:0030162 164 0.043
morphogenesis of embryonic epithelium GO:0016331 159 0.043
regulation of protein maturation GO:1903317 96 0.043
regulation of nucleotide catabolic process GO:0030811 122 0.042
ubiquitin dependent protein catabolic process GO:0006511 129 0.042
positive regulation of cell motility GO:2000147 116 0.042
spindle assembly involved in mitosis GO:0090307 4 0.042
regulation of extent of cell growth GO:0061387 52 0.042
cellular component assembly involved in morphogenesis GO:0010927 139 0.042
response to peptide hormone GO:0043434 127 0.042
t cell proliferation GO:0042098 120 0.041
monocarboxylic acid metabolic process GO:0032787 191 0.041
modification dependent macromolecule catabolic process GO:0043632 133 0.041
cellular protein catabolic process GO:0044257 155 0.041
cerebral cortex cell migration GO:0021795 44 0.041
nucleoside phosphate catabolic process GO:1901292 222 0.041
mitotic cell cycle process GO:1903047 159 0.040
Mouse
acetate ester transport GO:1901374 2 0.040
cellular chemical homeostasis GO:0055082 215 0.040
striated muscle myosin thick filament assembly GO:0071688 1 0.040
potassium ion transmembrane transport GO:0071805 43 0.039
rna localization GO:0006403 23 0.039
regulation of cell activation GO:0050865 289 0.039
organic anion transport GO:0015711 137 0.039
membrane protein proteolysis GO:0033619 10 0.039
negative regulation of interleukin 2 production GO:0032703 8 0.039
oxidation reduction process GO:0055114 342 0.039
nitrogen compound transport GO:0071705 271 0.039
leukocyte chemotaxis GO:0030595 69 0.038
positive regulation of protein kinase activity GO:0045860 144 0.038
regulation of potassium ion transmembrane transport GO:1901379 11 0.038
protein processing GO:0016485 163 0.038
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.038
response to transforming growth factor beta GO:0071559 88 0.038
regulation of chemotaxis GO:0050920 53 0.037
regulation of lymphocyte activation GO:0051249 240 0.037
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.037
negative regulation of nervous system development GO:0051961 156 0.037
Mouse
female gamete generation GO:0007292 74 0.037
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.037
Mouse
regulation of inclusion body assembly GO:0090083 1 0.037
organic acid catabolic process GO:0016054 51 0.037
response to iron ion GO:0010039 4 0.036
muscle cell development GO:0055001 133 0.036
negative regulation of protein processing GO:0010955 79 0.036
regulation of anatomical structure size GO:0090066 178 0.036
cellular transition metal ion homeostasis GO:0046916 32 0.036
positive regulation of mapk cascade GO:0043410 170 0.036
regulation of mitotic cell cycle phase transition GO:1901990 73 0.036
Mouse
metencephalon development GO:0022037 89 0.036
cellular alcohol metabolic process GO:0044107 3 0.036
regulation of transporter activity GO:0032409 57 0.035
t cell activation GO:0042110 289 0.035
microtubule based process GO:0007017 236 0.035
Mouse
sensory perception of touch GO:0050975 2 0.035
neuromuscular process controlling balance GO:0050885 59 0.035
angiogenesis GO:0001525 201 0.035
protein localization to organelle GO:0033365 185 0.034
positive regulation of peptidase activity GO:0010952 49 0.034
central nervous system neuron development GO:0021954 67 0.034
intrinsic apoptotic signaling pathway GO:0097193 132 0.034
positive regulation of growth GO:0045927 104 0.034
Worm
dorsal ventral axon guidance GO:0033563 3 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
positive regulation of cell substrate adhesion GO:0010811 47 0.034
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.034
actin filament based movement GO:0030048 23 0.034
organonitrogen compound catabolic process GO:1901565 264 0.033
cell cell junction assembly GO:0007043 27 0.033
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.033
multicellular organismal signaling GO:0035637 91 0.033
positive regulation of secretion by cell GO:1903532 114 0.033
lipid biosynthetic process GO:0008610 179 0.033
cell matrix adhesion GO:0007160 68 0.033
mesenchyme development GO:0060485 152 0.033
cellular modified amino acid metabolic process GO:0006575 63 0.033
peptidyl proline hydroxylation GO:0019511 3 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.032
calcium mediated signaling GO:0019722 46 0.032
regulation of cellular response to oxidative stress GO:1900407 19 0.032
negative regulation of kinase activity GO:0033673 81 0.032
glycerolipid metabolic process GO:0046486 122 0.032
cytoplasmic transport GO:0016482 234 0.032
reactive oxygen species biosynthetic process GO:1903409 8 0.032
regulation of translation GO:0006417 71 0.032
Mouse
carboxylic acid catabolic process GO:0046395 51 0.032
negative regulation of protein modification process GO:0031400 163 0.032
regulation of gtp catabolic process GO:0033124 113 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.031
Mouse
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.031
carboxylic acid transport GO:0046942 100 0.031
ribonucleoside monophosphate metabolic process GO:0009161 80 0.031
neuron projection extension GO:1990138 64 0.031
receptor internalization GO:0031623 16 0.031
positive regulation of transferase activity GO:0051347 167 0.031
calcium ion homeostasis GO:0055074 127 0.031
Mouse
mesodermal cell migration GO:0008078 4 0.031
organic acid biosynthetic process GO:0016053 86 0.031
gliogenesis GO:0042063 141 0.031
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.030
positive regulation of endocytosis GO:0045807 42 0.030
neuronal action potential GO:0019228 54 0.030
cell junction organization GO:0034330 77 0.030
lipid localization GO:0010876 126 0.030
erbb signaling pathway GO:0038127 32 0.030
cytoskeleton dependent intracellular transport GO:0030705 50 0.030
Mouse
aromatic compound catabolic process GO:0019439 286 0.030
regulation of metal ion transport GO:0010959 106 0.030
glycoprotein biosynthetic process GO:0009101 89 0.030
midbrain development GO:0030901 35 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
positive regulation of protein modification process GO:0031401 299 0.030
regulation of amyloid precursor protein catabolic process GO:1902991 8 0.029
leukocyte proliferation GO:0070661 172 0.029
negative regulation of mapk cascade GO:0043409 65 0.029
action potential GO:0001508 78 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
cyclic nucleotide metabolic process GO:0009187 59 0.029
regulation of ion transmembrane transporter activity GO:0032412 54 0.029
regulation of t cell proliferation GO:0042129 92 0.029
regulation of secretion GO:0051046 274 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
glycerophospholipid biosynthetic process GO:0046474 32 0.029
intracellular protein transport GO:0006886 204 0.029
positive regulation of protein export from nucleus GO:0046827 4 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.028
cell substrate adhesion GO:0031589 130 0.028
regulation of cell shape GO:0008360 39 0.028
negative regulation of endopeptidase activity GO:0010951 44 0.028
negative regulation of cell cycle GO:0045786 123 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.028
beta amyloid clearance GO:0097242 2 0.028
learning GO:0007612 98 0.027
Mouse
synaptic transmission GO:0007268 329 0.027
Mouse
divalent inorganic cation transport GO:0072511 178 0.027
positive regulation of sodium ion transport GO:0010765 13 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
positive regulation of kinase activity GO:0033674 155 0.027
forebrain generation of neurons GO:0021872 63 0.027
transmission of nerve impulse GO:0019226 76 0.027
ectodermal digestive tract development GO:0007439 1 0.027
actin filament organization GO:0007015 113 0.027
actin filament bundle assembly GO:0051017 40 0.027
cellular response to molecule of bacterial origin GO:0071219 83 0.027
actin mediated cell contraction GO:0070252 15 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
striated muscle tissue development GO:0014706 293 0.027
negative regulation of cell activation GO:0050866 111 0.027
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.027
sulfur compound metabolic process GO:0006790 100 0.027
regulation of clathrin mediated endocytosis GO:2000369 4 0.027
response to organic cyclic compound GO:0014070 198 0.027
embryonic epithelial tube formation GO:0001838 130 0.027
positive regulation of apoptotic process GO:0043065 217 0.026
negative regulation of leukocyte proliferation GO:0070664 46 0.026
positive regulation of response to wounding GO:1903036 66 0.026
maintenance of location GO:0051235 89 0.026
peptidyl amino acid modification GO:0018193 336 0.026
tube formation GO:0035148 140 0.026
organophosphate catabolic process GO:0046434 232 0.026
innate immune response GO:0045087 157 0.026
forebrain neuron development GO:0021884 30 0.026
pallium development GO:0021543 120 0.026
lymphocyte proliferation GO:0046651 164 0.026
digestive tract morphogenesis GO:0048546 147 0.026
cerebellum development GO:0021549 77 0.026
cerebellum morphogenesis GO:0021587 42 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
sensory organ morphogenesis GO:0090596 242 0.025
negative regulation of interleukin 17 production GO:0032700 5 0.025
protein localization to juxtaparanode region of axon GO:0071205 4 0.025
beta amyloid metabolic process GO:0050435 14 0.025
organic acid transport GO:0015849 101 0.025
negative regulation of map kinase activity GO:0043407 34 0.025
mating GO:0007618 27 0.025
spermatogenesis GO:0007283 284 0.025
negative regulation of beta amyloid formation GO:1902430 4 0.025
primary neural tube formation GO:0014020 95 0.025
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.024
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.024
oogenesis GO:0048477 56 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
oligodendrocyte differentiation GO:0048709 53 0.024
axon cargo transport GO:0008088 33 0.024
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
myotube differentiation GO:0014902 105 0.024
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.024
negative regulation of peptidase activity GO:0010466 46 0.024
homeostasis of number of cells GO:0048872 210 0.024

Aplp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.394
disease of anatomical entity DOID:7 0 0.394
nervous system disease DOID:863 0 0.394
brain disease DOID:936 0 0.347
disease of metabolism DOID:0014667 0 0.265
acquired metabolic disease DOID:0060158 0 0.265
amyloidosis DOID:9120 0 0.178
dementia DOID:1307 0 0.140
alzheimer s disease DOID:10652 0 0.140
disease of mental health DOID:150 0 0.140
tauopathy DOID:680 0 0.140
neurodegenerative disease DOID:1289 0 0.140
cognitive disorder DOID:1561 0 0.140
inherited metabolic disorder DOID:655 0 0.122
cerebral degeneration DOID:1443 0 0.102
disease of cellular proliferation DOID:14566 0 0.072
cancer DOID:162 0 0.064
cardiovascular system disease DOID:1287 0 0.053
organ system cancer DOID:0050686 0 0.043
musculoskeletal system disease DOID:17 0 0.030
connective tissue disease DOID:65 0 0.030
artery disease DOID:0050828 0 0.027
vascular disease DOID:178 0 0.027