Mus musculus

0 known processes

Arhgef1

Rho guanine nucleotide exchange factor (GEF) 1

(Aliases: Lbcl2,Lsc)

Arhgef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleotide metabolic process GO:0009150 290 0.847
Fly
actin cytoskeleton organization GO:0030036 220 0.845
Fly
stem cell maintenance GO:0019827 130 0.692
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.647
ribonucleoside triphosphate metabolic process GO:0009199 220 0.453
Fly
regulation of nucleotide metabolic process GO:0006140 169 0.431
Fly
small gtpase mediated signal transduction GO:0007264 97 0.400
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.367
Fly
ribonucleoside triphosphate catabolic process GO:0009203 199 0.349
Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.349
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.323
Fly
regulation of cell motility GO:2000145 236 0.283
glycosyl compound metabolic process GO:1901657 246 0.278
Fly
regulation of cell migration GO:0030334 219 0.266
leukocyte differentiation GO:0002521 342 0.247
regulation of myeloid cell differentiation GO:0045637 96 0.246
chemotaxis GO:0006935 247 0.237
amine metabolic process GO:0009308 45 0.229
membrane organization GO:0061024 245 0.229
regulation of chromatin modification GO:1903308 57 0.229
ribonucleoside metabolic process GO:0009119 245 0.229
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.215
Fly
nucleotide metabolic process GO:0009117 332 0.213
Fly
purine nucleoside catabolic process GO:0006152 205 0.211
Fly
ribonucleotide metabolic process GO:0009259 291 0.209
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.202
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.197
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.192
ribonucleotide catabolic process GO:0009261 208 0.191
Fly
negative regulation of cell development GO:0010721 169 0.191
neural precursor cell proliferation GO:0061351 121 0.190
photoreceptor cell morphogenesis GO:0008594 3 0.187
regulation of ras gtpase activity GO:0032318 88 0.186
Fly
positive regulation of catecholamine secretion GO:0033605 2 0.184
regulation of cellular amino acid metabolic process GO:0006521 5 0.181
ribose phosphate metabolic process GO:0019693 291 0.180
Fly
lymphocyte differentiation GO:0030098 242 0.177
intra golgi vesicle mediated transport GO:0006891 1 0.174
asymmetric neuroblast division GO:0055059 1 0.173
stem cell development GO:0048864 219 0.172
positive regulation of membrane potential GO:0045838 15 0.170
actomyosin structure organization GO:0031032 56 0.170
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.170
Fly
purine nucleoside triphosphate catabolic process GO:0009146 203 0.169
Fly
regulation of nucleoside metabolic process GO:0009118 130 0.164
Fly
localization within membrane GO:0051668 4 0.164
positive regulation of cellular component biogenesis GO:0044089 94 0.164
cellular ketone metabolic process GO:0042180 84 0.164
regulation of hydrolase activity GO:0051336 246 0.163
Fly
ribonucleoside catabolic process GO:0042454 206 0.158
Fly
cell adhesion GO:0007155 329 0.151
cell fate commitment GO:0045165 210 0.149
ameboidal type cell migration GO:0001667 128 0.149
regulation of protein localization GO:0032880 231 0.143
regulation of histone modification GO:0031056 56 0.143
regionalization GO:0003002 337 0.142
compartment pattern specification GO:0007386 4 0.138
stem cell differentiation GO:0048863 268 0.130
positive regulation of cell development GO:0010720 237 0.124
organic cyclic compound catabolic process GO:1901361 295 0.124
Fly
sequestering of metal ion GO:0051238 19 0.124
regulation of cell adhesion GO:0030155 154 0.122
purine ribonucleoside catabolic process GO:0046130 205 0.119
Fly
defecation GO:0030421 1 0.119
regulation of nucleotide catabolic process GO:0030811 122 0.117
Fly
regulation of organelle organization GO:0033043 289 0.115
retina morphogenesis in camera type eye GO:0060042 45 0.114
positive regulation of cell migration GO:0030335 109 0.112
b cell differentiation GO:0030183 78 0.111
organophosphate catabolic process GO:0046434 232 0.110
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.107
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.106
Fly
regulation of ion homeostasis GO:2000021 64 0.104
cellular homeostasis GO:0019725 240 0.104
positive regulation of nucleoside metabolic process GO:0045979 91 0.102
Fly
regulation of cellular component biogenesis GO:0044087 181 0.102
ras protein signal transduction GO:0007265 77 0.101
Fly
innate immune response GO:0045087 157 0.099
wnt signaling pathway GO:0016055 188 0.099
regulation of purine nucleotide catabolic process GO:0033121 122 0.098
Fly
endomembrane system organization GO:0010256 147 0.097
cellular amine metabolic process GO:0044106 44 0.096
peptidyl amino acid modification GO:0018193 336 0.096
carbohydrate derivative catabolic process GO:1901136 231 0.096
Fly
myeloid cell differentiation GO:0030099 233 0.094
regulation of cellular component size GO:0032535 121 0.093
nucleoside phosphate catabolic process GO:1901292 222 0.090
Fly
negative regulation of phagocytosis GO:0050765 4 0.090
regulation of cell cycle GO:0051726 281 0.090
cellular nitrogen compound catabolic process GO:0044270 280 0.090
Fly
protein localization to organelle GO:0033365 185 0.090
sensory perception of mechanical stimulus GO:0050954 107 0.089
Worm
purine nucleotide metabolic process GO:0006163 302 0.089
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.088
regulation of gtp catabolic process GO:0033124 113 0.087
Fly
cell substrate adhesion GO:0031589 130 0.087
response to osmotic stress GO:0006970 21 0.085
calcium ion transport into cytosol GO:0060402 48 0.085
tissue migration GO:0090130 68 0.085
nucleoside triphosphate metabolic process GO:0009141 230 0.085
Fly
release of sequestered calcium ion into cytosol GO:0051209 42 0.084
respiratory tube development GO:0030323 167 0.084
positive regulation of neuron projection development GO:0010976 79 0.084
establishment of organelle localization GO:0051656 122 0.083
positive regulation of cell motility GO:2000147 116 0.082
male gamete generation GO:0048232 285 0.082
entry into host GO:0044409 15 0.081
dendrite development GO:0016358 115 0.080
divalent inorganic cation transport GO:0072511 178 0.079
purine nucleoside metabolic process GO:0042278 241 0.078
Fly
protein localization to nucleus GO:0034504 121 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.078
regulation of homeostatic process GO:0032844 182 0.078
establishment or maintenance of cell polarity GO:0007163 86 0.077
muscle cell development GO:0055001 133 0.076
peptidyl threonine modification GO:0018210 31 0.076
myotube differentiation GO:0014902 105 0.076
appendage morphogenesis GO:0035107 149 0.076
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.075
rhythmic process GO:0048511 174 0.075
anion transmembrane transport GO:0098656 71 0.075
cation homeostasis GO:0055080 212 0.074
atp metabolic process GO:0046034 75 0.074
regulation of establishment of protein localization GO:0070201 181 0.074
sequestering of calcium ion GO:0051208 18 0.073
regulation of actin nucleation GO:0051125 4 0.073
morphogenesis of embryonic epithelium GO:0016331 159 0.072
Fly
cellular ion homeostasis GO:0006873 165 0.071
negative regulation of homeostatic process GO:0032845 71 0.071
synaptic transmission GO:0007268 329 0.071
negative regulation of cellular component organization GO:0051129 194 0.070
compound eye development GO:0048749 1 0.070
gtp catabolic process GO:0006184 143 0.069
Fly
regulation of kinase activity GO:0043549 249 0.069
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.069
Fly
cytosolic calcium ion homeostasis GO:0051480 70 0.067
peptidyl threonine phosphorylation GO:0018107 31 0.067
chromatin organization GO:0006325 206 0.067
lipid homeostasis GO:0055088 63 0.067
glycosyl compound catabolic process GO:1901658 206 0.066
Fly
regulation of metal ion transport GO:0010959 106 0.066
appendage development GO:0048736 166 0.065
Fly
cellular calcium ion homeostasis GO:0006874 119 0.065
sensory organ morphogenesis GO:0090596 242 0.065
lens development in camera type eye GO:0002088 62 0.065
smoothened signaling pathway GO:0007224 105 0.065
gonad development GO:0008406 141 0.064
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.064
tachykinin receptor signaling pathway GO:0007217 1 0.063
muscle cell differentiation GO:0042692 261 0.062
developmental growth involved in morphogenesis GO:0060560 138 0.062
Fly
actin filament organization GO:0007015 113 0.061
Fly
maintenance of location GO:0051235 89 0.061
neuron projection guidance GO:0097485 141 0.061
negative regulation of cell proliferation GO:0008285 296 0.061
regulation of ral gtpase activity GO:0032315 4 0.061
cellular response to cytokine stimulus GO:0071345 189 0.060
regulation of cytoskeleton organization GO:0051493 122 0.060
respiratory system development GO:0060541 190 0.060
Fly
positive regulation of chromatin modification GO:1903310 28 0.058
microtubule cytoskeleton organization GO:0000226 157 0.058
protein localization to plasma membrane GO:0072659 57 0.058
regulation of protein deacetylation GO:0090311 17 0.058
cellular response to organonitrogen compound GO:0071417 145 0.057
spermatid differentiation GO:0048515 115 0.057
t cell activation GO:0042110 289 0.055
regulation of secretion by cell GO:1903530 249 0.055
nucleoside metabolic process GO:0009116 246 0.055
Fly
epithelial cell migration GO:0010631 63 0.055
nucleotide catabolic process GO:0009166 217 0.055
Fly
nitrogen compound transport GO:0071705 271 0.055
ossification GO:0001503 216 0.054
negative regulation of cytoskeleton organization GO:0051494 36 0.053
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.052
divalent inorganic cation homeostasis GO:0072507 138 0.052
cellular divalent inorganic cation homeostasis GO:0072503 127 0.052
regulation of ras protein signal transduction GO:0046578 114 0.052
Fly
negative regulation of organelle organization GO:0010639 90 0.051
stem cell proliferation GO:0072089 117 0.051
regulation of cell projection organization GO:0031344 206 0.051
Fly
positive regulation of gtpase activity GO:0043547 85 0.051
Fly
positive regulation of dna templated transcription elongation GO:0032786 2 0.051
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.050
response to organonitrogen compound GO:0010243 246 0.050
vesicle organization GO:0016050 60 0.050
regulation of microtubule depolymerization GO:0031114 13 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.049
regulation of protein transport GO:0051223 163 0.049
regulation of osteoblast differentiation GO:0045667 67 0.048
negative regulation of viral release from host cell GO:1902187 6 0.048
regulation of myeloid leukocyte differentiation GO:0002761 58 0.047
establishment of protein localization to organelle GO:0072594 118 0.047
peptidyl serine modification GO:0018209 83 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.047
Fly
golgi vesicle transport GO:0048193 30 0.047
positive regulation of actin nucleation GO:0051127 3 0.047
regulation of intracellular transport GO:0032386 159 0.047
cellular response to acid chemical GO:0071229 68 0.047
asymmetric stem cell division GO:0098722 3 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
positive regulation of cell projection organization GO:0031346 95 0.046
endocrine system development GO:0035270 98 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.046
cellular protein complex assembly GO:0043623 116 0.046
microtubule based process GO:0007017 236 0.046
spermatogenesis GO:0007283 284 0.045
positive regulation of apoptotic signaling pathway GO:2001235 95 0.045
synapse assembly GO:0007416 56 0.045
cell junction organization GO:0034330 77 0.045
apoptotic signaling pathway GO:0097190 306 0.045
epithelium migration GO:0090132 63 0.045
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.044
dendritic spine development GO:0060996 30 0.044
nuclear division GO:0000280 158 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
positive regulation of protein modification process GO:0031401 299 0.044
defense response to bacterium GO:0042742 119 0.044
response to peptide GO:1901652 136 0.044
tissue homeostasis GO:0001894 115 0.044
photoreceptor cell differentiation GO:0046530 52 0.043
protein depolymerization GO:0051261 34 0.042
cellular response to peptide hormone stimulus GO:0071375 92 0.042
protein deacetylation GO:0006476 32 0.042
positive regulation of hydrolase activity GO:0051345 148 0.041
Fly
regulation of neuron projection development GO:0010975 169 0.041
Fly
ribonucleoside monophosphate metabolic process GO:0009161 80 0.041
lamellipodium organization GO:0097581 29 0.041
myosin filament assembly GO:0031034 2 0.041
cellular chemical homeostasis GO:0055082 215 0.041
somatic stem cell maintenance GO:0035019 47 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.040
cellular response to peptide GO:1901653 92 0.040
nucleoside monophosphate catabolic process GO:0009125 59 0.039
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.039
regulation of membrane potential GO:0042391 192 0.039
actin filament polymerization GO:0030041 44 0.039
negative regulation of nervous system development GO:0051961 156 0.038
regulation of vesicle mediated transport GO:0060627 139 0.038
neuroblast proliferation GO:0007405 49 0.038
multicellular organismal homeostasis GO:0048871 164 0.038
regulation of protein complex assembly GO:0043254 83 0.038
establishment of endothelial blood brain barrier GO:0014045 3 0.038
purine nucleotide catabolic process GO:0006195 211 0.037
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.037
immune response regulating signaling pathway GO:0002764 125 0.037
engulfment of apoptotic cell GO:0043652 3 0.037
peptidyl serine phosphorylation GO:0018105 74 0.037
spleen development GO:0048536 39 0.037
skeletal system development GO:0001501 356 0.037
regulation of stem cell maintenance GO:2000036 17 0.037
locomotory behavior GO:0007626 195 0.037
divalent metal ion transport GO:0070838 172 0.037
axonogenesis GO:0007409 274 0.037
Fly
lung development GO:0030324 164 0.037
calcium ion homeostasis GO:0055074 127 0.037
regulation of cell cycle process GO:0010564 160 0.037
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.036
regulation of protein kinase activity GO:0045859 232 0.036
embryonic limb morphogenesis GO:0030326 126 0.036
regulation of calcium ion transport into cytosol GO:0010522 31 0.036
ovulation cycle GO:0042698 59 0.036
regulation of actin cytoskeleton organization GO:0032956 84 0.035
nuclear transport GO:0051169 139 0.035
syncytium formation GO:0006949 43 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
hemostasis GO:0007599 78 0.035
negative regulation of molecular function GO:0044092 258 0.035
mesoderm formation GO:0001707 62 0.035
skin development GO:0043588 220 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
regulation of chromosome organization GO:0033044 83 0.034
nucleoside monophosphate metabolic process GO:0009123 85 0.034
response to organic cyclic compound GO:0014070 198 0.034
maintenance of protein location in cell GO:0032507 20 0.034
development of secondary male sexual characteristics GO:0046544 3 0.034
heart contraction GO:0060047 93 0.034
regulation of actin filament polymerization GO:0030833 38 0.033
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.033
endoderm development GO:0007492 45 0.033
diencephalon development GO:0021536 63 0.033
peptidyl tyrosine phosphorylation GO:0018108 143 0.033
sensory perception GO:0007600 245 0.033
Worm
purine nucleoside monophosphate catabolic process GO:0009128 58 0.033
viral gene expression GO:0019080 3 0.033
adherens junction organization GO:0034332 28 0.033
ovarian follicle development GO:0001541 40 0.033
response to acid chemical GO:0001101 111 0.033
response to reactive oxygen species GO:0000302 56 0.032
primary neural tube formation GO:0014020 95 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
positive regulation of secretion GO:0051047 130 0.032
regulation of ion transport GO:0043269 215 0.032
cd4 positive alpha beta t cell activation GO:0035710 45 0.032
regulation of protein localization to nucleus GO:1900180 60 0.032
nucleoside catabolic process GO:0009164 206 0.031
Fly
organelle localization GO:0051640 179 0.031
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.031
regulation of mast cell differentiation GO:0060375 3 0.031
retina development in camera type eye GO:0060041 119 0.031
calcium ion transport GO:0006816 159 0.031
mitotic nuclear division GO:0007067 48 0.031
i kappab kinase nf kappab signaling GO:0007249 85 0.031
response to growth factor GO:0070848 198 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
cytokine production GO:0001816 319 0.030
heterocycle catabolic process GO:0046700 280 0.030
Fly
cation transport GO:0006812 399 0.030
morphogenesis of a polarized epithelium GO:0001738 37 0.030
forebrain development GO:0030900 302 0.030
neuron migration GO:0001764 122 0.030
cytosolic calcium ion transport GO:0060401 48 0.030
positive regulation of protein transport GO:0051222 93 0.029
lipid storage GO:0019915 36 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
positive regulation of nervous system development GO:0051962 221 0.029
regulation of chromatin organization GO:1902275 57 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
negative regulation of viral transcription GO:0032897 3 0.028
endocytosis GO:0006897 168 0.028
response to lipopolysaccharide GO:0032496 128 0.028
positive regulation of histone modification GO:0031058 28 0.028
cytoplasmic transport GO:0016482 234 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
cell matrix adhesion GO:0007160 68 0.028
epidermis development GO:0008544 187 0.028
organelle fission GO:0048285 170 0.027
regulation of synapse structural plasticity GO:0051823 4 0.027
leukocyte migration GO:0050900 124 0.027
development of primary sexual characteristics GO:0045137 143 0.027
defense response to other organism GO:0098542 197 0.027
dna templated transcription termination GO:0006353 4 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
Fly
focal adhesion assembly GO:0048041 19 0.027
cellular component assembly involved in morphogenesis GO:0010927 139 0.026
regulation of organ morphogenesis GO:2000027 144 0.026
protein import into nucleus GO:0006606 95 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
Fly
urogenital system development GO:0001655 261 0.026
circadian rhythm GO:0007623 114 0.026
methylation GO:0032259 134 0.026
positive regulation of protein localization to nucleus GO:1900182 30 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
cartilage development GO:0051216 140 0.026
regulation of smoothened signaling pathway GO:0008589 58 0.026
limb development GO:0060173 166 0.025
purine nucleoside monophosphate metabolic process GO:0009126 81 0.025
tube formation GO:0035148 140 0.025
neuromuscular process GO:0050905 99 0.025
atp catabolic process GO:0006200 55 0.025
pigmentation GO:0043473 71 0.025
mesoderm development GO:0007498 100 0.025
peptide transport GO:0015833 133 0.025
chromatin modification GO:0016568 187 0.025
dna metabolic process GO:0006259 303 0.025
leukocyte proliferation GO:0070661 172 0.025
intracellular protein transport GO:0006886 204 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
uropod organization GO:0032796 2 0.025
cell cell junction organization GO:0045216 72 0.025
aromatic compound catabolic process GO:0019439 286 0.025
Fly
epithalamus development GO:0021538 2 0.025
negative adaptation of signaling pathway GO:0022401 5 0.025
purine containing compound metabolic process GO:0072521 311 0.024
Fly
axon guidance GO:0007411 141 0.024
germ cell development GO:0007281 185 0.024
peptidyl lysine modification GO:0018205 77 0.024
protein deacylation GO:0035601 36 0.024
anatomical structure homeostasis GO:0060249 145 0.024
adherens junction assembly GO:0034333 22 0.024
response to inorganic substance GO:0010035 96 0.024
homotypic cell cell adhesion GO:0034109 28 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
homeostasis of number of cells GO:0048872 210 0.023
macromolecule catabolic process GO:0009057 281 0.023
movement in host environment GO:0052126 15 0.023
kidney development GO:0001822 213 0.023
protein targeting GO:0006605 143 0.023
cell growth GO:0016049 130 0.023
Fly
mammary gland epithelium development GO:0061180 65 0.023
actin cytoskeleton reorganization GO:0031532 21 0.023
Fly
cellular response to interferon gamma GO:0071346 25 0.023
circulatory system process GO:0003013 197 0.023
rab protein signal transduction GO:0032482 1 0.023
proteasomal protein catabolic process GO:0010498 98 0.023
activation of immune response GO:0002253 138 0.023
acylglycerol biosynthetic process GO:0046463 18 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of multi organism process GO:0043900 111 0.023
spindle localization GO:0051653 22 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
Fly
positive regulation of innate immune response GO:0045089 80 0.023
modification dependent protein catabolic process GO:0019941 133 0.022
rho protein signal transduction GO:0007266 32 0.022
Fly
positive regulation of kinase activity GO:0033674 155 0.022
regulation of defense response GO:0031347 233 0.022
myeloid leukocyte differentiation GO:0002573 119 0.022
digestive system development GO:0055123 200 0.022
Fly
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.022
blastocyst development GO:0001824 80 0.022
regulation of leukocyte proliferation GO:0070663 121 0.022
positive regulation of lipid metabolic process GO:0045834 40 0.022
regulation of ral protein signal transduction GO:0032485 4 0.022
striated muscle contraction GO:0006941 45 0.021
embryonic skeletal system development GO:0048706 120 0.021
skeletal system morphogenesis GO:0048705 203 0.021
regulation of cell activation GO:0050865 289 0.021
metal ion homeostasis GO:0055065 189 0.021
cellular protein catabolic process GO:0044257 155 0.021
response to light stimulus GO:0009416 135 0.021
negative regulation of synapse assembly GO:0051964 3 0.021
positive regulation of rho gtpase activity GO:0032321 41 0.021
Fly
organic hydroxy compound transport GO:0015850 93 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
blood circulation GO:0008015 195 0.021
viral transcription GO:0019083 3 0.021
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.020
regulation of t cell differentiation GO:0045580 83 0.020
regulation of neuron differentiation GO:0045664 281 0.020
Fly
cellular metal ion homeostasis GO:0006875 151 0.020
cell chemotaxis GO:0060326 81 0.020
regulation of blood circulation GO:1903522 93 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
anion transport GO:0006820 177 0.020
ear development GO:0043583 200 0.020
positive regulation of cytoskeleton organization GO:0051495 49 0.020
regulation of secretion GO:0051046 274 0.020
entry into other organism involved in symbiotic interaction GO:0051828 15 0.020
synapse organization GO:0050808 125 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
receptor mediated endocytosis GO:0006898 51 0.020
regulation of t cell proliferation GO:0042129 92 0.019
cellular response to interleukin 4 GO:0071353 21 0.019
sterol homeostasis GO:0055092 45 0.019
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.019
taurine metabolic process GO:0019530 4 0.019
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.019
myosin filament organization GO:0031033 3 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
Fly
b cell activation GO:0042113 161 0.019
embryonic appendage morphogenesis GO:0035113 126 0.019
protein secretion GO:0009306 111 0.019
male gonad development GO:0008584 88 0.019
protein autophosphorylation GO:0046777 61 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.019
regulation of t cell activation GO:0050863 170 0.019
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
neurotransmitter transport GO:0006836 76 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.018
negative regulation of ras protein signal transduction GO:0046580 18 0.018
steroid metabolic process GO:0008202 119 0.018
action potential GO:0001508 78 0.018
multicellular organism growth GO:0035264 161 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
Fly
positive regulation of programmed cell death GO:0043068 218 0.018
camera type eye development GO:0043010 266 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.018
sulfur compound metabolic process GO:0006790 100 0.018
regulation of histone acetylation GO:0035065 19 0.018
cellular response to salt stress GO:0071472 1 0.018
positive regulation of transcription via serum response element binding GO:0010735 1 0.018
regulation of viral entry into host cell GO:0046596 12 0.018
syncytium formation by plasma membrane fusion GO:0000768 42 0.018
myofibril assembly GO:0030239 34 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
adult behavior GO:0030534 135 0.018
mitotic cell cycle process GO:1903047 159 0.017
blood coagulation GO:0007596 76 0.017
purine containing compound catabolic process GO:0072523 213 0.017
Fly
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of myotube differentiation GO:0010830 62 0.017
adult locomotory behavior GO:0008344 91 0.017
stem cell division GO:0017145 30 0.017
response to peptide hormone GO:0043434 127 0.017
neuron projection extension GO:1990138 64 0.017
regulation of nuclear division GO:0051783 56 0.017
positive regulation of defense response GO:0031349 124 0.017
protein desumoylation GO:0016926 2 0.017
female gonad development GO:0008585 71 0.017
regulation of viral release from host cell GO:1902186 6 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
mesenchymal cell development GO:0014031 93 0.017

Arhgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
myopathy DOID:423 0 0.025
muscular disease DOID:0080000 0 0.025
heart disease DOID:114 0 0.025
cardiomyopathy DOID:0050700 0 0.025
cardiovascular system disease DOID:1287 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscle tissue disease DOID:66 0 0.025