Mus musculus

0 known processes

Arhgef11

Rho guanine nucleotide exchange factor (GEF) 11

(Aliases: KIAA0380,RhoGEF,B930073M02,E130307F09,mKIAA0380,MGC90827)

Arhgef11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cerebellar granule cell precursor tangential migration GO:0021935 1 1.000
facial nerve structural organization GO:0021612 10 0.999
postganglionic parasympathetic nervous system development GO:0021784 2 0.998
anterior commissure morphogenesis GO:0021960 6 0.997
facial nerve development GO:0021561 11 0.997
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.996
glossopharyngeal nerve morphogenesis GO:0021615 4 0.995
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.994
trigeminal nerve morphogenesis GO:0021636 6 0.992
facial nerve morphogenesis GO:0021610 11 0.989
negative regulation of axon guidance GO:1902668 8 0.985
chemorepulsion of branchiomotor axon GO:0021793 1 0.982
branchiomotor neuron axon guidance GO:0021785 7 0.980
vagus nerve development GO:0021564 3 0.978
semaphorin plexin signaling pathway GO:0071526 21 0.975
negative regulation of axon extension GO:0030517 19 0.974
central nervous system projection neuron axonogenesis GO:0021952 21 0.973
negative regulation of osteoblast proliferation GO:0033689 4 0.971
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.969
ossification involved in bone maturation GO:0043931 12 0.967
branching involved in salivary gland morphogenesis GO:0060445 26 0.964
negative chemotaxis GO:0050919 14 0.960
trigeminal nerve structural organization GO:0021637 6 0.955
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.954
positive regulation of rho gtpase activity GO:0032321 41 0.952
anatomical structure arrangement GO:0048532 20 0.945
hindbrain tangential cell migration GO:0021934 2 0.939
regulation of rho gtpase activity GO:0032319 58 0.936
trigeminal nerve development GO:0021559 10 0.900
centrosome localization GO:0051642 13 0.896
ras protein signal transduction GO:0007265 77 0.889
Human
rho protein signal transduction GO:0007266 32 0.885
Human
central nervous system neuron axonogenesis GO:0021955 28 0.884
limb bud formation GO:0060174 10 0.882
negative regulation of cell projection organization GO:0031345 56 0.881
gtp catabolic process GO:0006184 143 0.865
smooth muscle cell migration GO:0014909 10 0.863
regulation of ras gtpase activity GO:0032318 88 0.851
cranial nerve structural organization GO:0021604 13 0.842
guanosine containing compound metabolic process GO:1901068 144 0.837
regulation of negative chemotaxis GO:0050923 1 0.828
vagus nerve morphogenesis GO:0021644 2 0.822
regulation of gtp catabolic process GO:0033124 113 0.818
positive regulation of gtp catabolic process GO:0033126 85 0.814
guanosine containing compound catabolic process GO:1901069 144 0.807
gtp metabolic process GO:0046039 144 0.806
positive regulation of gtpase activity GO:0043547 85 0.804
positive regulation of ras gtpase activity GO:0032320 65 0.802
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.792
stem cell proliferation GO:0072089 117 0.785
tube closure GO:0060606 91 0.776
salivary gland development GO:0007431 37 0.776
skeletal system development GO:0001501 356 0.775
regulation of smooth muscle cell migration GO:0014910 6 0.764
negative regulation of chemotaxis GO:0050922 11 0.761
regulation of axon extension GO:0030516 43 0.752
motor neuron axon guidance GO:0008045 26 0.752
muscle cell migration GO:0014812 19 0.746
nucleoside triphosphate metabolic process GO:0009141 230 0.746
anatomical structure maturation GO:0071695 49 0.743
regulation of rho protein signal transduction GO:0035023 71 0.733
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.718
pyramidal neuron development GO:0021860 8 0.716
small gtpase mediated signal transduction GO:0007264 97 0.715
Human
ribose phosphate metabolic process GO:0019693 291 0.711
bone maturation GO:0070977 13 0.709
appendage morphogenesis GO:0035107 149 0.708
neural tube development GO:0021915 160 0.708
morphogenesis of embryonic epithelium GO:0016331 159 0.707
regulation of neuron migration GO:2001222 22 0.706
negative regulation of behavior GO:0048521 14 0.704
organ maturation GO:0048799 17 0.704
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.703
ribonucleoside triphosphate catabolic process GO:0009203 199 0.698
parasympathetic nervous system development GO:0048486 19 0.679
positive regulation of cytoskeleton organization GO:0051495 49 0.675
regulation of osteoblast proliferation GO:0033688 15 0.670
forebrain neuron development GO:0021884 30 0.668
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.665
negative regulation of neuron projection development GO:0010977 50 0.662
regulation of cellular catabolic process GO:0031329 242 0.661
neuron projection extension GO:1990138 64 0.660
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.658
sympathetic nervous system development GO:0048485 22 0.657
embryonic epithelial tube formation GO:0001838 130 0.655
regulation of ras protein signal transduction GO:0046578 114 0.650
organophosphate catabolic process GO:0046434 232 0.648
bone trabecula morphogenesis GO:0061430 12 0.645
purine nucleotide metabolic process GO:0006163 302 0.645
regulation of nucleoside metabolic process GO:0009118 130 0.642
tube formation GO:0035148 140 0.642
neural tube closure GO:0001843 90 0.641
limb development GO:0060173 166 0.639
neural precursor cell proliferation GO:0061351 121 0.631
positive regulation of nucleotide catabolic process GO:0030813 88 0.629
purine ribonucleoside metabolic process GO:0046128 241 0.629
purine nucleoside triphosphate catabolic process GO:0009146 203 0.626
purine nucleotide catabolic process GO:0006195 211 0.625
hindbrain development GO:0030902 128 0.625
purine ribonucleoside catabolic process GO:0046130 205 0.624
regulation of extent of cell growth GO:0061387 52 0.623
tissue migration GO:0090130 68 0.621
positive regulation of cellular catabolic process GO:0031331 148 0.618
regulation of purine nucleotide catabolic process GO:0033121 122 0.615
purine containing compound catabolic process GO:0072523 213 0.613
pharyngeal system development GO:0060037 17 0.613
regulation of binding GO:0051098 111 0.612
telencephalon development GO:0021537 186 0.611
regulation of nucleotide catabolic process GO:0030811 122 0.611
developmental growth involved in morphogenesis GO:0060560 138 0.607
glycosyl compound metabolic process GO:1901657 246 0.603
primary neural tube formation GO:0014020 95 0.603
regulation of purine nucleotide metabolic process GO:1900542 169 0.602
regulation of nucleotide metabolic process GO:0006140 169 0.601
nucleotide catabolic process GO:0009166 217 0.600
purine nucleoside triphosphate metabolic process GO:0009144 226 0.600
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.598
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.588
forebrain neuron differentiation GO:0021879 52 0.585
negative regulation of cell development GO:0010721 169 0.585
appendage development GO:0048736 166 0.584
central nervous system neuron development GO:0021954 67 0.584
purine ribonucleotide metabolic process GO:0009150 290 0.582
heterocycle catabolic process GO:0046700 280 0.577
glycosyl compound catabolic process GO:1901658 206 0.574
cranial nerve development GO:0021545 41 0.573
positive regulation of binding GO:0051099 49 0.572
somite development GO:0061053 81 0.570
negative regulation of cell growth GO:0030308 44 0.569
nucleoside triphosphate catabolic process GO:0009143 205 0.565
positive regulation of neuron projection development GO:0010976 79 0.563
osteoblast proliferation GO:0033687 18 0.563
positive regulation of nucleoside metabolic process GO:0045979 91 0.561
regulation of cell size GO:0008361 72 0.560
organic cyclic compound catabolic process GO:1901361 295 0.554
epithelial tube morphogenesis GO:0060562 303 0.550
ribonucleoside triphosphate metabolic process GO:0009199 220 0.546
cell migration in hindbrain GO:0021535 16 0.543
purine ribonucleotide catabolic process GO:0009154 208 0.542
positive regulation of nucleotide metabolic process GO:0045981 114 0.529
nucleoside metabolic process GO:0009116 246 0.528
purine nucleoside catabolic process GO:0006152 205 0.527
ribonucleoside metabolic process GO:0009119 245 0.525
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.524
cellular nitrogen compound catabolic process GO:0044270 280 0.515
regulation of protein binding GO:0043393 60 0.514
nucleoside catabolic process GO:0009164 206 0.513
negative regulation of neuron differentiation GO:0045665 101 0.511
cranial nerve morphogenesis GO:0021602 26 0.510
ribonucleotide catabolic process GO:0009261 208 0.509
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.504
phosphatidylinositol mediated signaling GO:0048015 41 0.503
hippocampus development GO:0021766 52 0.503
organonitrogen compound catabolic process GO:1901565 264 0.499
purine nucleoside metabolic process GO:0042278 241 0.496
nucleobase containing small molecule metabolic process GO:0055086 352 0.493
regulation of axon guidance GO:1902667 13 0.490
epithelial tube formation GO:0072175 130 0.487
regionalization GO:0003002 337 0.485
regulation of cellular component size GO:0032535 121 0.485
blood vessel morphogenesis GO:0048514 285 0.484
outflow tract morphogenesis GO:0003151 53 0.482
regulation of chemotaxis GO:0050920 53 0.481
purine containing compound metabolic process GO:0072521 311 0.479
axon guidance GO:0007411 141 0.469
autonomic nervous system development GO:0048483 43 0.465
regulation of neuron projection development GO:0010975 169 0.464
somitogenesis GO:0001756 69 0.463
regulation of vasculature development GO:1901342 88 0.461
ribonucleoside catabolic process GO:0042454 206 0.458
carbohydrate derivative catabolic process GO:1901136 231 0.457
positive regulation of neuron differentiation GO:0045666 141 0.457
positive regulation of hydrolase activity GO:0051345 148 0.454
negative regulation of cellular component organization GO:0051129 194 0.452
epithelial cell migration GO:0010631 63 0.452
morphogenesis of a branching epithelium GO:0061138 193 0.451
nucleotide metabolic process GO:0009117 332 0.448
ribonucleotide metabolic process GO:0009259 291 0.448
negative regulation of growth GO:0045926 99 0.445
limbic system development GO:0021761 72 0.442
nucleoside phosphate metabolic process GO:0006753 338 0.441
positive regulation of organelle organization GO:0010638 128 0.436
negative regulation of nervous system development GO:0051961 156 0.436
central nervous system neuron differentiation GO:0021953 162 0.431
axon extension involved in axon guidance GO:0048846 14 0.420
organelle localization GO:0051640 179 0.419
epithelium migration GO:0090132 63 0.419
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.418
aromatic compound catabolic process GO:0019439 286 0.412
inositol lipid mediated signaling GO:0048017 41 0.412
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.411
regulation of cell projection organization GO:0031344 206 0.411
regulation of neuron differentiation GO:0045664 281 0.408
ossification GO:0001503 216 0.407
pyramidal neuron differentiation GO:0021859 9 0.406
forebrain development GO:0030900 302 0.405
pallium development GO:0021543 120 0.404
regulation of cell motility GO:2000145 236 0.403
nucleoside phosphate catabolic process GO:1901292 222 0.403
neuron migration GO:0001764 122 0.399
gland development GO:0048732 330 0.392
axonogenesis GO:0007409 274 0.386
regulation of cytoskeleton organization GO:0051493 122 0.383
positive regulation of nervous system development GO:0051962 221 0.377
peripheral nervous system development GO:0007422 53 0.373
heart morphogenesis GO:0003007 178 0.367
positive regulation of cell projection organization GO:0031346 95 0.366
regulation of hydrolase activity GO:0051336 246 0.363
positive regulation of cell development GO:0010720 237 0.363
endothelial cell migration GO:0043542 44 0.361
trabecula morphogenesis GO:0061383 40 0.359
neuroblast proliferation GO:0007405 49 0.353
nerve development GO:0021675 67 0.353
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.346
branching morphogenesis of an epithelial tube GO:0048754 159 0.343
forebrain generation of neurons GO:0021872 63 0.332
segmentation GO:0035282 93 0.325
positive regulation of protein binding GO:0032092 29 0.320
cell growth GO:0016049 130 0.313
synapse assembly GO:0007416 56 0.307
morphogenesis of a branching structure GO:0001763 203 0.305
salivary gland morphogenesis GO:0007435 33 0.297
preganglionic parasympathetic nervous system development GO:0021783 17 0.294
developmental maturation GO:0021700 193 0.293
regulation of cell growth GO:0001558 91 0.291
glossopharyngeal nerve development GO:0021563 5 0.286
limb morphogenesis GO:0035108 149 0.268
ameboidal type cell migration GO:0001667 128 0.260
negative regulation of cell proliferation GO:0008285 296 0.258
neuron projection guidance GO:0097485 141 0.246
developmental cell growth GO:0048588 84 0.246
chemotaxis GO:0006935 247 0.240
regulation of cell shape GO:0008360 39 0.234
regulation of cell migration GO:0030334 219 0.219
regulation of organelle organization GO:0033043 289 0.201
angiogenesis GO:0001525 201 0.148
negative regulation of cell adhesion GO:0007162 45 0.132
regulation of angiogenesis GO:0045765 81 0.132
cell adhesion GO:0007155 329 0.128
regulation of cell adhesion GO:0030155 154 0.118
regulation of anatomical structure size GO:0090066 178 0.087
synapse organization GO:0050808 125 0.082
exocrine system development GO:0035272 45 0.066
neural tube formation GO:0001841 108 0.059
negative regulation of molecular function GO:0044092 258 0.046
g protein coupled receptor signaling pathway GO:0007186 243 0.042
Human
bone development GO:0060348 120 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
negative regulation of phosphate metabolic process GO:0045936 184 0.037
actin cytoskeleton organization GO:0030036 220 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.033
cellular amino acid metabolic process GO:0006520 103 0.031
amine metabolic process GO:0009308 45 0.030
epithelial cell proliferation GO:0050673 174 0.029
multicellular organismal signaling GO:0035637 91 0.028
sensory perception GO:0007600 245 0.027
macromolecule catabolic process GO:0009057 281 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
negative regulation of nucleotide catabolic process GO:0030812 9 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
protein targeting GO:0006605 143 0.021
cell chemotaxis GO:0060326 81 0.020
regulation of secretion GO:0051046 274 0.020
positive regulation of cell death GO:0010942 224 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cell cycle GO:0051726 281 0.019
response to growth factor GO:0070848 198 0.018
cellular ketone metabolic process GO:0042180 84 0.018
regulation of epithelial cell proliferation GO:0050678 141 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.018
cation transmembrane transport GO:0098655 266 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
intracellular protein transport GO:0006886 204 0.017
protein localization to organelle GO:0033365 185 0.017
methylation GO:0032259 134 0.017
leukocyte differentiation GO:0002521 342 0.017
immune effector process GO:0002252 321 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of cell activation GO:0050865 289 0.016
chromatin organization GO:0006325 206 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
inflammatory response GO:0006954 244 0.016
transmembrane transport GO:0055085 412 0.015
germ cell development GO:0007281 185 0.015
neuronal action potential GO:0019228 54 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
apoptotic signaling pathway GO:0097190 306 0.015
actin filament organization GO:0007015 113 0.015
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.015
positive regulation of protein modification process GO:0031401 299 0.015
regulation of secretion by cell GO:1903530 249 0.014
actin filament based movement GO:0030048 23 0.014
stem cell differentiation GO:0048863 268 0.014
response to organonitrogen compound GO:0010243 246 0.014
negative regulation of cell motility GO:2000146 61 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
respiratory system development GO:0060541 190 0.014
negative regulation of immune system process GO:0002683 209 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
oxidation reduction process GO:0055114 342 0.014
endothelial cell proliferation GO:0001935 27 0.014
dna metabolic process GO:0006259 303 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
negative regulation of cell activation GO:0050866 111 0.013
compound eye development GO:0048749 1 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
mitotic cell cycle GO:0000278 195 0.013
cellular amine metabolic process GO:0044106 44 0.013
cellular chemical homeostasis GO:0055082 215 0.013
chromatin modification GO:0016568 187 0.013
organelle fission GO:0048285 170 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
action potential GO:0001508 78 0.013
negative regulation of gtpase activity GO:0034260 6 0.013
locomotory behavior GO:0007626 195 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
dna repair GO:0006281 107 0.013
cognition GO:0050890 149 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
cellular lipid metabolic process GO:0044255 323 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
negative regulation of nucleotide metabolic process GO:0045980 16 0.012
mitotic cell cycle process GO:1903047 159 0.012
regulation of cytokine production GO:0001817 266 0.012
wnt signaling pathway GO:0016055 188 0.012
spermatogenesis GO:0007283 284 0.012
regulation of intracellular transport GO:0032386 159 0.012
carbohydrate metabolic process GO:0005975 230 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
actin mediated cell contraction GO:0070252 15 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
rab protein signal transduction GO:0032482 1 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
endomembrane system organization GO:0010256 147 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
myeloid cell differentiation GO:0030099 233 0.012
single organism cell adhesion GO:0098602 156 0.012
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of embryonic development GO:0045995 71 0.011
positive regulation of epithelial cell proliferation GO:0050679 68 0.011
dephosphorylation GO:0016311 129 0.011
sprouting angiogenesis GO:0002040 26 0.011
rhythmic process GO:0048511 174 0.011
protein maturation GO:0051604 176 0.011
regulation of protein kinase activity GO:0045859 232 0.011
histone modification GO:0016570 159 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
protein catabolic process GO:0030163 221 0.011
microtubule based process GO:0007017 236 0.011
mitochondrion organization GO:0007005 134 0.011
response to insulin GO:0032868 100 0.011
protein processing GO:0016485 163 0.011
male gamete generation GO:0048232 285 0.011
cellular homeostasis GO:0019725 240 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
digestive system development GO:0055123 200 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
cytokine production GO:0001816 319 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of kinase activity GO:0043549 249 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.010
spermatid differentiation GO:0048515 115 0.010
positive chemotaxis GO:0050918 18 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
urogenital system development GO:0001655 261 0.010
regulation of proteolysis GO:0030162 164 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
gliogenesis GO:0042063 141 0.010
organelle assembly GO:0070925 177 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
ion transmembrane transport GO:0034220 361 0.010
ear development GO:0043583 200 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
regulation of feeding behavior GO:0060259 3 0.010
establishment of protein localization to organelle GO:0072594 118 0.010

Arhgef11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.039
cancer DOID:162 0 0.034
organ system cancer DOID:0050686 0 0.033
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.014
immune system cancer DOID:0060083 0 0.013