Mus musculus

0 known processes

Arhgef12

Rho guanine nucleotide exchange factor (GEF) 12

(Aliases: KIAA0380,mKIAA0382,AU019857,Larg,2310014B11Rik)

Arhgef12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cerebellar granule cell precursor tangential migration GO:0021935 1 0.976
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.878
postganglionic parasympathetic nervous system development GO:0021784 2 0.748
regulation of cell projection organization GO:0031344 206 0.673
Fly
small gtpase mediated signal transduction GO:0007264 97 0.667
Fly
glossopharyngeal nerve morphogenesis GO:0021615 4 0.659
regulation of anatomical structure size GO:0090066 178 0.656
anterior commissure morphogenesis GO:0021960 6 0.655
purine ribonucleotide metabolic process GO:0009150 290 0.639
Fly
embryonic epithelial tube formation GO:0001838 130 0.637
regionalization GO:0003002 337 0.602
ribonucleotide metabolic process GO:0009259 291 0.574
Fly
glycosyl compound catabolic process GO:1901658 206 0.556
Fly
positive regulation of ras gtpase activity GO:0032320 65 0.540
Fly
neural tube formation GO:0001841 108 0.535
chemorepulsion of branchiomotor axon GO:0021793 1 0.534
purine nucleotide metabolic process GO:0006163 302 0.533
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.527
Fly
regulation of ras gtpase activity GO:0032318 88 0.525
Fly
organophosphate catabolic process GO:0046434 232 0.512
Fly
purine containing compound metabolic process GO:0072521 311 0.510
Fly
nucleoside catabolic process GO:0009164 206 0.504
Fly
organelle localization GO:0051640 179 0.493
nucleobase containing small molecule metabolic process GO:0055086 352 0.488
Fly
regulation of protein binding GO:0043393 60 0.483
regulation of cell size GO:0008361 72 0.481
heterocycle catabolic process GO:0046700 280 0.480
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.470
Fly
positive regulation of nucleotide catabolic process GO:0030813 88 0.460
Fly
ribose phosphate metabolic process GO:0019693 291 0.450
Fly
regulation of cell motility GO:2000145 236 0.442
negative regulation of osteoblast proliferation GO:0033689 4 0.431
regulation of cell adhesion GO:0030155 154 0.427
primary neural tube formation GO:0014020 95 0.427
regulation of cytoskeleton organization GO:0051493 122 0.424
central nervous system projection neuron axonogenesis GO:0021952 21 0.410
purine containing compound catabolic process GO:0072523 213 0.401
Fly
neuron projection guidance GO:0097485 141 0.398
glycosyl compound metabolic process GO:1901657 246 0.395
Fly
neural tube closure GO:0001843 90 0.392
regulation of cell migration GO:0030334 219 0.389
forebrain development GO:0030900 302 0.389
vagus nerve development GO:0021564 3 0.383
regulation of gtp catabolic process GO:0033124 113 0.377
Fly
neural tube development GO:0021915 160 0.376
purine nucleoside metabolic process GO:0042278 241 0.374
Fly
cell adhesion GO:0007155 329 0.374
epithelial tube formation GO:0072175 130 0.373
regulation of cellular component size GO:0032535 121 0.365
gtp catabolic process GO:0006184 143 0.364
Fly
guanosine containing compound catabolic process GO:1901069 144 0.351
Fly
epithelial tube morphogenesis GO:0060562 303 0.348
regulation of nucleoside metabolic process GO:0009118 130 0.346
Fly
nucleotide metabolic process GO:0009117 332 0.345
Fly
ribonucleoside metabolic process GO:0009119 245 0.345
Fly
branchiomotor neuron axon guidance GO:0021785 7 0.342
regulation of purine nucleotide catabolic process GO:0033121 122 0.342
Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.341
Fly
tube closure GO:0060606 91 0.340
negative regulation of axon guidance GO:1902668 8 0.339
regulation of ras protein signal transduction GO:0046578 114 0.337
Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.336
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.335
Fly
semaphorin plexin signaling pathway GO:0071526 21 0.326
regulation of transferase activity GO:0051338 263 0.324
organic cyclic compound catabolic process GO:1901361 295 0.323
Fly
gtp metabolic process GO:0046039 144 0.322
Fly
axon guidance GO:0007411 141 0.306
chemotaxis GO:0006935 247 0.303
nucleoside triphosphate catabolic process GO:0009143 205 0.293
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.290
Fly
rho protein signal transduction GO:0007266 32 0.282
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.281
Fly
trigeminal nerve morphogenesis GO:0021636 6 0.279
purine ribonucleoside catabolic process GO:0046130 205 0.272
Fly
regulation of rho protein signal transduction GO:0035023 71 0.271
Fly
hindbrain tangential cell migration GO:0021934 2 0.270
regulation of protein kinase activity GO:0045859 232 0.259
regulation of neuron differentiation GO:0045664 281 0.258
Fly
regulation of neuron projection development GO:0010975 169 0.258
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.256
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.254
Fly
positive regulation of nucleotide metabolic process GO:0045981 114 0.246
Fly
aromatic compound catabolic process GO:0019439 286 0.245
Fly
purine nucleotide catabolic process GO:0006195 211 0.240
Fly
nucleoside metabolic process GO:0009116 246 0.238
Fly
gland development GO:0048732 330 0.233
branching involved in salivary gland morphogenesis GO:0060445 26 0.232
positive regulation of cell projection organization GO:0031346 95 0.232
central nervous system neuron differentiation GO:0021953 162 0.230
regulation of rho gtpase activity GO:0032319 58 0.227
Fly
positive regulation of organelle organization GO:0010638 128 0.225
ameboidal type cell migration GO:0001667 128 0.220
anatomical structure arrangement GO:0048532 20 0.216
negative regulation of cell proliferation GO:0008285 296 0.216
ribonucleoside triphosphate catabolic process GO:0009203 199 0.211
Fly
developmental cell growth GO:0048588 84 0.204
positive regulation of gtp catabolic process GO:0033126 85 0.201
Fly
guanosine containing compound metabolic process GO:1901068 144 0.199
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.198
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.196
Fly
actin cytoskeleton organization GO:0030036 220 0.194
Fly
vagus nerve morphogenesis GO:0021644 2 0.193
regulation of extent of cell growth GO:0061387 52 0.193
appendage development GO:0048736 166 0.193
Fly
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.192
nucleotide catabolic process GO:0009166 217 0.190
Fly
regulation of cellular catabolic process GO:0031329 242 0.188
Fly
hippocampus development GO:0021766 52 0.181
regulation of nucleotide metabolic process GO:0006140 169 0.176
Fly
regulation of axon extension GO:0030516 43 0.174
neuron projection extension GO:1990138 64 0.168
tube formation GO:0035148 140 0.167
positive regulation of cell development GO:0010720 237 0.166
forebrain generation of neurons GO:0021872 63 0.160
central nervous system neuron axonogenesis GO:0021955 28 0.160
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.155
Fly
ossification involved in bone maturation GO:0043931 12 0.151
heart morphogenesis GO:0003007 178 0.149
negative chemotaxis GO:0050919 14 0.149
negative regulation of cell development GO:0010721 169 0.149
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.149
purine nucleoside triphosphate catabolic process GO:0009146 203 0.148
Fly
morphogenesis of a branching structure GO:0001763 203 0.145
hindbrain development GO:0030902 128 0.145
endothelial cell migration GO:0043542 44 0.144
epithelium migration GO:0090132 63 0.143
facial nerve structural organization GO:0021612 10 0.142
telencephalon development GO:0021537 186 0.138
somitogenesis GO:0001756 69 0.138
branching morphogenesis of an epithelial tube GO:0048754 159 0.136
negative regulation of neuron projection development GO:0010977 50 0.136
limb morphogenesis GO:0035108 149 0.133
positive regulation of cytoskeleton organization GO:0051495 49 0.132
regulation of chemotaxis GO:0050920 53 0.129
regulation of cell growth GO:0001558 91 0.126
appendage morphogenesis GO:0035107 149 0.125
Fly
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.123
regulation of cellular response to stress GO:0080135 159 0.123
limb development GO:0060173 166 0.122
morphogenesis of a branching epithelium GO:0061138 193 0.121
negative regulation of molecular function GO:0044092 258 0.120
forebrain neuron development GO:0021884 30 0.118
g protein coupled receptor signaling pathway GO:0007186 243 0.118
Human
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.118
negative regulation of growth GO:0045926 99 0.116
positive regulation of binding GO:0051099 49 0.115
negative regulation of cell adhesion GO:0007162 45 0.114
regulation of mapk cascade GO:0043408 248 0.114
peripheral nervous system development GO:0007422 53 0.113
stem cell proliferation GO:0072089 117 0.112
negative regulation of nervous system development GO:0051961 156 0.111
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.111
phosphatidylinositol mediated signaling GO:0048015 41 0.107
nucleoside phosphate metabolic process GO:0006753 338 0.106
Fly
muscle cell migration GO:0014812 19 0.104
regulation of kinase activity GO:0043549 249 0.103
sympathetic nervous system development GO:0048485 22 0.101
cell migration in hindbrain GO:0021535 16 0.101
regulation of vasculature development GO:1901342 88 0.101
segmentation GO:0035282 93 0.100
epithelial cell migration GO:0010631 63 0.099
regulation of cell shape GO:0008360 39 0.098
Fly
establishment of organelle localization GO:0051656 122 0.098
regulation of nucleotide catabolic process GO:0030811 122 0.097
Fly
angiogenesis GO:0001525 201 0.096
regulation of binding GO:0051098 111 0.095
regulation of cellular amine metabolic process GO:0033238 20 0.091
actin filament polymerization GO:0030041 44 0.091
ossification GO:0001503 216 0.091
negative regulation of axon extension GO:0030517 19 0.090
negative regulation of cellular component organization GO:0051129 194 0.089
microtubule based process GO:0007017 236 0.089
positive regulation of neuron differentiation GO:0045666 141 0.089
cellular ketone metabolic process GO:0042180 84 0.088
negative regulation of cell projection organization GO:0031345 56 0.087
axon extension involved in axon guidance GO:0048846 14 0.086
pallium development GO:0021543 120 0.085
regulation of organelle organization GO:0033043 289 0.084
negative regulation of chemotaxis GO:0050922 11 0.084
facial nerve morphogenesis GO:0021610 11 0.084
positive regulation of nucleoside metabolic process GO:0045979 91 0.083
Fly
olfactory learning GO:0008355 2 0.083
ras protein signal transduction GO:0007265 77 0.082
Fly
negative regulation of neuron differentiation GO:0045665 101 0.082
facial nerve development GO:0021561 11 0.082
cranial nerve structural organization GO:0021604 13 0.081
positive regulation of hydrolase activity GO:0051345 148 0.081
Fly
regulation of axon guidance GO:1902667 13 0.081
positive regulation of protein binding GO:0032092 29 0.080
limbic system development GO:0021761 72 0.080
cytoskeleton dependent intracellular transport GO:0030705 50 0.079
positive regulation of nervous system development GO:0051962 221 0.078
wnt signaling pathway GO:0016055 188 0.077
negative regulation of phosphorus metabolic process GO:0010563 184 0.076
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.076
blood vessel morphogenesis GO:0048514 285 0.075
salivary gland development GO:0007431 37 0.075
negative regulation of phosphate metabolic process GO:0045936 184 0.075
tissue migration GO:0090130 68 0.074
negative regulation of behavior GO:0048521 14 0.074
skeletal system development GO:0001501 356 0.073
synapse assembly GO:0007416 56 0.073
positive regulation of protein kinase activity GO:0045860 144 0.073
amine metabolic process GO:0009308 45 0.072
forebrain neuron differentiation GO:0021879 52 0.072
salivary gland morphogenesis GO:0007435 33 0.071
mapk cascade GO:0000165 281 0.069
trabecula morphogenesis GO:0061383 40 0.068
response to growth factor GO:0070848 198 0.066
cell growth GO:0016049 130 0.065
Fly
smooth muscle cell migration GO:0014909 10 0.064
trigeminal nerve development GO:0021559 10 0.064
regulation of negative chemotaxis GO:0050923 1 0.063
myosin filament assembly GO:0031034 2 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
positive regulation of protein phosphorylation GO:0001934 242 0.062
ribonucleotide catabolic process GO:0009261 208 0.061
Fly
positive regulation of kinase activity GO:0033674 155 0.061
synapse organization GO:0050808 125 0.061
cell junction assembly GO:0034329 52 0.061
developmental maturation GO:0021700 193 0.060
regulation of cytokine production GO:0001817 266 0.060
morphogenesis of embryonic epithelium GO:0016331 159 0.060
Fly
apical constriction GO:0003383 4 0.060
regulation of neuron migration GO:2001222 22 0.059
cellular response to growth factor stimulus GO:0071363 197 0.059
centrosome localization GO:0051642 13 0.059
ion transmembrane transport GO:0034220 361 0.059
actin polymerization or depolymerization GO:0008154 54 0.059
negative regulation of phosphorylation GO:0042326 166 0.058
regulation of protein serine threonine kinase activity GO:0071900 157 0.057
apoptotic signaling pathway GO:0097190 306 0.057
negative regulation of cell growth GO:0030308 44 0.057
transmembrane transport GO:0055085 412 0.057
positive regulation of cellular component biogenesis GO:0044089 94 0.056
positive regulation of rho gtpase activity GO:0032321 41 0.056
Fly
neuron migration GO:0001764 122 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.054
memory GO:0007613 58 0.054
neural precursor cell proliferation GO:0061351 121 0.054
cellular amino acid metabolic process GO:0006520 103 0.053
cell substrate adhesion GO:0031589 130 0.053
leukocyte migration GO:0050900 124 0.053
negative regulation of protein phosphorylation GO:0001933 126 0.052
cognition GO:0050890 149 0.052
microtubule based movement GO:0007018 84 0.051
regulation of osteoblast proliferation GO:0033688 15 0.051
motor neuron axon guidance GO:0008045 26 0.051
outflow tract morphogenesis GO:0003151 53 0.051
dendrite development GO:0016358 115 0.051
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.051
cell recognition GO:0008037 83 0.051
positive regulation of gtpase activity GO:0043547 85 0.050
Fly
regulation of wnt signaling pathway GO:0030111 123 0.050
cyclic nucleotide metabolic process GO:0009187 59 0.050
cellular amine metabolic process GO:0044106 44 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
muscle cell differentiation GO:0042692 261 0.049
positive regulation of neuron projection development GO:0010976 79 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
microtubule cytoskeleton organization GO:0000226 157 0.048
trigeminal nerve structural organization GO:0021637 6 0.047
circulatory system process GO:0003013 197 0.047
carbohydrate derivative catabolic process GO:1901136 231 0.047
Fly
regulation of actin filament polymerization GO:0030833 38 0.046
oocyte axis specification GO:0007309 2 0.046
limb bud formation GO:0060174 10 0.046
cellular protein complex assembly GO:0043623 116 0.046
digestive tract morphogenesis GO:0048546 147 0.046
Fly
neuroblast proliferation GO:0007405 49 0.045
ribonucleoside catabolic process GO:0042454 206 0.044
Fly
rhythmic process GO:0048511 174 0.044
regulation of actin cytoskeleton organization GO:0032956 84 0.044
carbohydrate derivative biosynthetic process GO:1901137 183 0.044
somite development GO:0061053 81 0.044
regulation of angiogenesis GO:0045765 81 0.044
cytokine production GO:0001816 319 0.044
circadian rhythm GO:0007623 114 0.043
regulation of stress activated mapk cascade GO:0032872 69 0.043
posttranscriptional regulation of gene expression GO:0010608 155 0.043
regulation of vesicle mediated transport GO:0060627 139 0.043
cranial nerve development GO:0021545 41 0.043
axonogenesis GO:0007409 274 0.043
Fly
negative regulation of protein metabolic process GO:0051248 282 0.042
bone development GO:0060348 120 0.042
establishment or maintenance of cell polarity GO:0007163 86 0.041
regulation of cell activation GO:0050865 289 0.041
inositol lipid mediated signaling GO:0048017 41 0.041
regulation of hippo signaling GO:0035330 1 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
pharyngeal system development GO:0060037 17 0.041
protein polymerization GO:0051258 57 0.041
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.040
endocytosis GO:0006897 168 0.040
regulation of membrane potential GO:0042391 192 0.040
extrinsic apoptotic signaling pathway GO:0097191 126 0.040
cell type specific apoptotic process GO:0097285 268 0.040
locomotory behavior GO:0007626 195 0.040
adherens junction organization GO:0034332 28 0.039
pyramidal neuron development GO:0021860 8 0.039
response to light stimulus GO:0009416 135 0.039
regulation of actin filament length GO:0030832 45 0.039
regulation of smooth muscle cell migration GO:0014910 6 0.038
striated muscle myosin thick filament assembly GO:0071688 1 0.038
organonitrogen compound biosynthetic process GO:1901566 192 0.038
regulation of multi organism process GO:0043900 111 0.038
regulation of actin polymerization or depolymerization GO:0008064 45 0.037
regulation of endocytosis GO:0030100 69 0.037
cellular homeostasis GO:0019725 240 0.036
anatomical structure maturation GO:0071695 49 0.036
parasympathetic nervous system development GO:0048486 19 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.035
exocrine system development GO:0035272 45 0.035
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
Fly
cellular macromolecule catabolic process GO:0044265 206 0.035
protein localization to membrane GO:0072657 108 0.034
regulation of neuron death GO:1901214 134 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
epithelial cell development GO:0002064 159 0.034
organ maturation GO:0048799 17 0.033
ribose phosphate biosynthetic process GO:0046390 59 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
neuromuscular process controlling balance GO:0050885 59 0.033
neuron apoptotic process GO:0051402 142 0.033
regulation of ion transmembrane transport GO:0034765 119 0.033
cell matrix adhesion GO:0007160 68 0.033
negative regulation of immune system process GO:0002683 209 0.033
actin filament organization GO:0007015 113 0.033
Fly
phagocytosis GO:0006909 66 0.033
bone trabecula morphogenesis GO:0061430 12 0.033
exocytosis GO:0006887 121 0.032
sensory perception GO:0007600 245 0.032
Worm
nerve development GO:0021675 67 0.032
neuron death GO:0070997 154 0.031
peptidyl tyrosine phosphorylation GO:0018108 143 0.031
cellular response to dna damage stimulus GO:0006974 207 0.031
oocyte construction GO:0007308 2 0.031
plus end directed organelle transport along microtubule GO:0072386 2 0.031
central nervous system neuron development GO:0021954 67 0.031
cell maturation GO:0048469 127 0.031
calcium ion transmembrane transport GO:0070588 85 0.030
positive regulation of transferase activity GO:0051347 167 0.030
learning or memory GO:0007611 148 0.030
metencephalon development GO:0022037 89 0.030
negative regulation of protein modification process GO:0031400 163 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
positive regulation of endocytosis GO:0045807 42 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.029
microtubule based transport GO:0010970 50 0.028
respiratory tube development GO:0030323 167 0.028
myeloid cell differentiation GO:0030099 233 0.028
regulation of protein complex assembly GO:0043254 83 0.028
regulation of response to wounding GO:1903034 189 0.028
retina development in camera type eye GO:0060041 119 0.028
body morphogenesis GO:0010171 45 0.028
regulation of cellular response to growth factor stimulus GO:0090287 82 0.028
lung development GO:0030324 164 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.027
camera type eye development GO:0043010 266 0.027
cellular lipid metabolic process GO:0044255 323 0.027
cell junction organization GO:0034330 77 0.027
macromolecule catabolic process GO:0009057 281 0.027
positive regulation of protein modification process GO:0031401 299 0.027
leukocyte differentiation GO:0002521 342 0.027
autonomic nervous system development GO:0048483 43 0.026
intracellular protein transport GO:0006886 204 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
Fly
cell substrate adherens junction assembly GO:0007045 19 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
preganglionic parasympathetic nervous system development GO:0021783 17 0.026
actin filament based movement GO:0030048 23 0.026
Fly
stress activated mapk cascade GO:0051403 80 0.026
cell cell junction organization GO:0045216 72 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
positive regulation of cell motility GO:2000147 116 0.026
sequestering of calcium ion GO:0051208 18 0.025
t cell activation GO:0042110 289 0.025
negative regulation of kinase activity GO:0033673 81 0.025
stress activated protein kinase signaling cascade GO:0031098 81 0.025
bone maturation GO:0070977 13 0.025
regulation of protein localization GO:0032880 231 0.025
nucleoside phosphate biosynthetic process GO:1901293 79 0.025
regulation of microtubule based process GO:0032886 52 0.025
mesodermal cell migration GO:0008078 4 0.025
regulation of secretion GO:0051046 274 0.025
purine nucleotide biosynthetic process GO:0006164 65 0.025
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.024
adherens junction assembly GO:0034333 22 0.024
glossopharyngeal nerve development GO:0021563 5 0.024
multicellular organism growth GO:0035264 161 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
skeletal system morphogenesis GO:0048705 203 0.024
regulation of cell cycle process GO:0010564 160 0.024
negative regulation of neuron death GO:1901215 98 0.024
cation homeostasis GO:0055080 212 0.024
glycerolipid metabolic process GO:0046486 122 0.024
myotube differentiation GO:0014902 105 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
positive regulation of cell cycle GO:0045787 92 0.023
regulation of t cell activation GO:0050863 170 0.023
osteoblast proliferation GO:0033687 18 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
stem cell development GO:0048864 219 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
compound eye development GO:0048749 1 0.023
regulation of feeding behavior GO:0060259 3 0.023
positive regulation of cell adhesion GO:0045785 80 0.023
male gamete generation GO:0048232 285 0.023
engulfment of apoptotic cell GO:0043652 3 0.023
regulation of defense response GO:0031347 233 0.022
metal ion homeostasis GO:0055065 189 0.022
maintenance of location GO:0051235 89 0.022
cell substrate junction assembly GO:0007044 24 0.022
digestive system development GO:0055123 200 0.022
Fly
inflammatory response GO:0006954 244 0.022
cation transport GO:0006812 399 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
adult behavior GO:0030534 135 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
regulation of microtubule cytoskeleton organization GO:0070507 37 0.022
establishment of vesicle localization GO:0051650 81 0.022
syncytium formation GO:0006949 43 0.022
purine ribonucleotide biosynthetic process GO:0009152 59 0.021
retina morphogenesis in camera type eye GO:0060042 45 0.021
respiratory system development GO:0060541 190 0.021
Fly
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
purine containing compound biosynthetic process GO:0072522 70 0.021
response to extracellular stimulus GO:0009991 127 0.021
membrane organization GO:0061024 245 0.021
cation transmembrane transport GO:0098655 266 0.021
immune effector process GO:0002252 321 0.021
regulation of actin filament based process GO:0032970 99 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
jnk cascade GO:0007254 72 0.021
positive regulation of cell death GO:0010942 224 0.021
reactive oxygen species metabolic process GO:0072593 84 0.020
kidney epithelium development GO:0072073 121 0.020
smoothened signaling pathway GO:0007224 105 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
actin mediated cell contraction GO:0070252 15 0.020
Fly
positive regulation of cell migration GO:0030335 109 0.020
glycoprotein metabolic process GO:0009100 116 0.020
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.020
regulation of cell substrate adhesion GO:0010810 73 0.020
renal system development GO:0072001 225 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
glycerophospholipid metabolic process GO:0006650 71 0.020
endomembrane system organization GO:0010256 147 0.020
cellular chemical homeostasis GO:0055082 215 0.020
regulation of hydrolase activity GO:0051336 246 0.019
Fly
adult locomotory behavior GO:0008344 91 0.019
response to lipopolysaccharide GO:0032496 128 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.019
response to organonitrogen compound GO:0010243 246 0.019
regulation of receptor activity GO:0010469 41 0.019
regulation of map kinase activity GO:0043405 120 0.019
spermatogenesis GO:0007283 284 0.019
innate immune response GO:0045087 157 0.019
regulation of circadian rhythm GO:0042752 58 0.019
positive regulation of ion transport GO:0043270 65 0.019
response to insulin GO:0032868 100 0.019
sterol metabolic process GO:0016125 58 0.018
protein localization to organelle GO:0033365 185 0.018
digestive tract development GO:0048565 190 0.018
Fly
axon cargo transport GO:0008088 33 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
response to radiation GO:0009314 165 0.018
lipid biosynthetic process GO:0008610 179 0.018
cytoplasmic transport GO:0016482 234 0.018
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.018
syncytium formation by plasma membrane fusion GO:0000768 42 0.018
ribonucleotide biosynthetic process GO:0009260 59 0.018
defense response to other organism GO:0098542 197 0.018
regulation of system process GO:0044057 200 0.018
positive regulation of phagocytosis GO:0050766 26 0.018
glucose homeostasis GO:0042593 128 0.017
cyclic nucleotide biosynthetic process GO:0009190 44 0.017
fatty acid metabolic process GO:0006631 121 0.017
second messenger mediated signaling GO:0019932 73 0.017
pyramidal neuron differentiation GO:0021859 9 0.017
extracellular matrix organization GO:0030198 147 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
golgi to endosome transport GO:0006895 3 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
negative regulation of transferase activity GO:0051348 85 0.017

Arhgef12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
musculoskeletal system disease DOID:17 0 0.042
central nervous system disease DOID:331 0 0.027
nervous system disease DOID:863 0 0.027
connective tissue disease DOID:65 0 0.020