Mus musculus

195 known processes

Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

(Aliases: Lfc,Lbcl1,GEFH1,mKIAA0651,GEF,AA408978,LFP40,GEF-H1,P40)

Arhgef2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.861
glycosyl compound catabolic process GO:1901658 206 0.855
actin cytoskeleton organization GO:0030036 220 0.843
organonitrogen compound catabolic process GO:1901565 264 0.730
purine nucleotide metabolic process GO:0006163 302 0.669
carbohydrate derivative catabolic process GO:1901136 231 0.625
nucleoside triphosphate catabolic process GO:0009143 205 0.611
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.600
purine ribonucleoside metabolic process GO:0046128 241 0.593
heterocycle catabolic process GO:0046700 280 0.573
purine ribonucleotide metabolic process GO:0009150 290 0.515
synaptic vesicle transport GO:0048489 57 0.514
gtp metabolic process GO:0046039 144 0.512
aromatic compound catabolic process GO:0019439 286 0.507
ribonucleoside catabolic process GO:0042454 206 0.488
cellular nitrogen compound catabolic process GO:0044270 280 0.474
actomyosin structure organization GO:0031032 56 0.456
organic cyclic compound catabolic process GO:1901361 295 0.454
synaptic transmission GO:0007268 329 0.425
cerebellar granule cell precursor tangential migration GO:0021935 1 0.416
purine nucleoside metabolic process GO:0042278 241 0.397
purine nucleotide catabolic process GO:0006195 211 0.395
purine nucleoside triphosphate metabolic process GO:0009144 226 0.387
ribonucleotide metabolic process GO:0009259 291 0.386
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.379
actin filament bundle assembly GO:0051017 40 0.370
organophosphate catabolic process GO:0046434 232 0.351
single organism cell adhesion GO:0098602 156 0.344
nucleoside catabolic process GO:0009164 206 0.329
purine nucleoside triphosphate catabolic process GO:0009146 203 0.315
regulation of neuron differentiation GO:0045664 281 0.306
cellular component assembly involved in morphogenesis GO:0010927 139 0.305
small gtpase mediated signal transduction GO:0007264 97 0.288
ribonucleoside metabolic process GO:0009119 245 0.287
actin filament organization GO:0007015 113 0.286
nucleoside phosphate metabolic process GO:0006753 338 0.286
positive regulation of cell development GO:0010720 237 0.279
regulation of cell motility GO:2000145 236 0.277
nucleoside phosphate catabolic process GO:1901292 222 0.277
positive regulation of organelle organization GO:0010638 128 0.269
purine nucleoside catabolic process GO:0006152 205 0.267
positive regulation of neuron differentiation GO:0045666 141 0.261
ribonucleotide catabolic process GO:0009261 208 0.258
negative regulation of protein phosphorylation GO:0001933 126 0.252
regulation of apoptotic signaling pathway GO:2001233 197 0.249
glycosyl compound metabolic process GO:1901657 246 0.243
purine ribonucleoside catabolic process GO:0046130 205 0.222
ribonucleoside triphosphate catabolic process GO:0009203 199 0.218
nucleotide catabolic process GO:0009166 217 0.213
purine containing compound catabolic process GO:0072523 213 0.202
purine containing compound metabolic process GO:0072521 311 0.187
nucleoside metabolic process GO:0009116 246 0.185
axonogenesis GO:0007409 274 0.183
amine metabolic process GO:0009308 45 0.181
t cell activation GO:0042110 289 0.180
cellular response to organonitrogen compound GO:0071417 145 0.168
Human
guanosine containing compound metabolic process GO:1901068 144 0.166
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.162
coagulation GO:0050817 78 0.158
nucleobase containing small molecule metabolic process GO:0055086 352 0.152
purine ribonucleotide catabolic process GO:0009154 208 0.147
negative regulation of neuron death GO:1901215 98 0.143
positive regulation of nervous system development GO:0051962 221 0.141
regulation of neuron projection development GO:0010975 169 0.141
regulation of actin cytoskeleton organization GO:0032956 84 0.138
negative regulation of protein metabolic process GO:0051248 282 0.137
microtubule based movement GO:0007018 84 0.134
organelle assembly GO:0070925 177 0.132
establishment of synaptic vesicle localization GO:0097480 57 0.132
nucleotide metabolic process GO:0009117 332 0.126
microtubule based process GO:0007017 236 0.124
response to organic cyclic compound GO:0014070 198 0.122
regulation of organelle organization GO:0033043 289 0.121
Human
positive regulation of phospholipid translocation GO:0061092 2 0.117
cilium morphogenesis GO:0060271 102 0.116
axon guidance GO:0007411 141 0.116
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.115
synaptic vesicle localization GO:0097479 59 0.113
blood vessel morphogenesis GO:0048514 285 0.112
cell type specific apoptotic process GO:0097285 268 0.112
membrane organization GO:0061024 245 0.111
sensory organ morphogenesis GO:0090596 242 0.110
learning or memory GO:0007611 148 0.109
epidermis development GO:0008544 187 0.109
ribonucleoside triphosphate metabolic process GO:0009199 220 0.106
actin filament severing GO:0051014 1 0.106
apoptotic signaling pathway GO:0097190 306 0.106
myeloid cell differentiation GO:0030099 233 0.105
neural tube closure GO:0001843 90 0.105
leukocyte differentiation GO:0002521 342 0.104
regulation of cytoskeleton organization GO:0051493 122 0.104
Human
muscle contraction GO:0006936 101 0.104
cell adhesion GO:0007155 329 0.103
regulation of cell cycle GO:0051726 281 0.102
regionalization GO:0003002 337 0.101
negative regulation of apoptotic signaling pathway GO:2001234 104 0.100
intermediate filament based process GO:0045103 27 0.100
regulation of cell migration GO:0030334 219 0.100
negative regulation of synapse assembly GO:0051964 3 0.098
spermatogenesis GO:0007283 284 0.098
neural tube development GO:0021915 160 0.097
muscle tissue development GO:0060537 308 0.095
cognition GO:0050890 149 0.095
cell cell junction organization GO:0045216 72 0.094
regulation of neurotransmitter levels GO:0001505 87 0.094
regulation of purine nucleotide catabolic process GO:0033121 122 0.094
dendrite development GO:0016358 115 0.093
gastrulation GO:0007369 116 0.092
positive regulation of neuron projection development GO:0010976 79 0.091
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.091
regulation of cellular amine metabolic process GO:0033238 20 0.090
negative regulation of synaptic vesicle transport GO:1902804 3 0.089
skeletal system development GO:0001501 356 0.088
hematopoietic progenitor cell differentiation GO:0002244 143 0.086
gtp catabolic process GO:0006184 143 0.085
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.085
neural tube formation GO:0001841 108 0.084
cellular amine metabolic process GO:0044106 44 0.084
cytoplasmic transport GO:0016482 234 0.083
response to organonitrogen compound GO:0010243 246 0.082
Human
primary neural tube formation GO:0014020 95 0.082
microtubule cytoskeleton organization GO:0000226 157 0.081
cellular amino acid metabolic process GO:0006520 103 0.081
anion transport GO:0006820 177 0.080
angiogenesis GO:0001525 201 0.080
response to radiation GO:0009314 165 0.079
muscle cell differentiation GO:0042692 261 0.079
regulation of endothelial cell apoptotic process GO:2000351 9 0.078
inner ear receptor cell development GO:0060119 39 0.077
cardiac muscle contraction GO:0060048 32 0.076
skin development GO:0043588 220 0.075
dna metabolic process GO:0006259 303 0.073
cellular homeostasis GO:0019725 240 0.073
negative regulation of fibroblast migration GO:0010764 2 0.073
alpha beta t cell activation GO:0046631 91 0.072
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.071
nucleoside triphosphate metabolic process GO:0009141 230 0.071
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.071
intracellular protein transport GO:0006886 204 0.069
regulation of cell substrate adhesion GO:0010810 73 0.069
sensory perception of sound GO:0007605 97 0.069
t cell differentiation GO:0030217 174 0.069
macromolecule catabolic process GO:0009057 281 0.068
trunk neural crest cell migration GO:0036484 4 0.068
protein processing GO:0016485 163 0.067
muscle system process GO:0003012 141 0.067
regulation of cellular component biogenesis GO:0044087 181 0.067
intracellular receptor signaling pathway GO:0030522 74 0.066
positive regulation of cellular component biogenesis GO:0044089 94 0.066
chemotaxis GO:0006935 247 0.066
photoreceptor cell development GO:0042461 40 0.065
homeostasis of number of cells GO:0048872 210 0.065
striated muscle contraction GO:0006941 45 0.065
mitotic cell cycle GO:0000278 195 0.064
regulation of cellular catabolic process GO:0031329 242 0.064
regulation of vesicle mediated transport GO:0060627 139 0.063
positive regulation of ras gtpase activity GO:0032320 65 0.063
developmental maturation GO:0021700 193 0.062
blood coagulation GO:0007596 76 0.061
sensory perception of mechanical stimulus GO:0050954 107 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.061
regulation of map kinase activity GO:0043405 120 0.061
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.061
cellular ketone metabolic process GO:0042180 84 0.061
sialylation GO:0097503 14 0.061
regulation of ral gtpase activity GO:0032315 4 0.061
myeloid cell homeostasis GO:0002262 114 0.061
rhythmic process GO:0048511 174 0.060
regulation of neuron death GO:1901214 134 0.060
ameboidal type cell migration GO:0001667 128 0.060
transmembrane transport GO:0055085 412 0.059
neurotransmitter secretion GO:0007269 62 0.059
learning GO:0007612 98 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.058
lymphocyte differentiation GO:0030098 242 0.058
ion transmembrane transport GO:0034220 361 0.058
neuron projection guidance GO:0097485 141 0.057
multicellular organism growth GO:0035264 161 0.057
ribose phosphate metabolic process GO:0019693 291 0.057
establishment or maintenance of cell polarity GO:0007163 86 0.057
sensory perception GO:0007600 245 0.056
platelet aggregation GO:0070527 20 0.056
extrinsic apoptotic signaling pathway GO:0097191 126 0.056
regulation of neuron apoptotic process GO:0043523 122 0.056
fibroblast migration GO:0010761 21 0.055
cell junction organization GO:0034330 77 0.055
cell substrate adhesion GO:0031589 130 0.054
bone development GO:0060348 120 0.054
regulation of hydrolase activity GO:0051336 246 0.054
cilium assembly GO:0042384 81 0.054
adherens junction maintenance GO:0034334 1 0.053
negative regulation of cellular amine metabolic process GO:0033239 1 0.053
negative regulation of protein modification process GO:0031400 163 0.053
embryonic epithelial tube formation GO:0001838 130 0.053
regulation of proteolysis GO:0030162 164 0.053
regulation of nucleotide metabolic process GO:0006140 169 0.052
regulation of blood circulation GO:1903522 93 0.051
regulation of ras gtpase activity GO:0032318 88 0.051
platelet activation GO:0030168 40 0.051
synapse assembly GO:0007416 56 0.051
protein localization to organelle GO:0033365 185 0.050
muscle fiber development GO:0048747 76 0.050
cd4 positive alpha beta t cell activation GO:0035710 45 0.050
chemorepulsion of branchiomotor axon GO:0021793 1 0.050
positive regulation of cytoskeleton organization GO:0051495 49 0.050
organic acid transport GO:0015849 101 0.050
male gamete generation GO:0048232 285 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.049
intermediate filament cytoskeleton organization GO:0045104 26 0.049
establishment of vesicle localization GO:0051650 81 0.048
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.048
protein maturation GO:0051604 176 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
positive regulation of cellular catabolic process GO:0031331 148 0.048
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.048
cell junction assembly GO:0034329 52 0.047
telencephalon development GO:0021537 186 0.047
regulation of ion transport GO:0043269 215 0.047
regulation of anatomical structure size GO:0090066 178 0.047
peptidyl amino acid modification GO:0018193 336 0.046
Human
cellular response to dna damage stimulus GO:0006974 207 0.046
erythrocyte differentiation GO:0030218 88 0.046
regulation of protein localization GO:0032880 231 0.046
cellular protein catabolic process GO:0044257 155 0.046
negative regulation of phosphorylation GO:0042326 166 0.046
rho protein signal transduction GO:0007266 32 0.045
regulation of cell projection organization GO:0031344 206 0.045
cellular response to organic cyclic compound GO:0071407 87 0.045
germ cell development GO:0007281 185 0.045
mitotic cell cycle process GO:1903047 159 0.045
regulation of vasculature development GO:1901342 88 0.045
alpha beta t cell differentiation GO:0046632 69 0.044
single organismal cell cell adhesion GO:0016337 131 0.044
mapk cascade GO:0000165 281 0.044
multicellular organismal homeostasis GO:0048871 164 0.044
fertilization GO:0009566 127 0.043
organic anion transport GO:0015711 137 0.043
positive regulation of nucleotide catabolic process GO:0030813 88 0.043
neuron neuron synaptic transmission GO:0007270 69 0.043
organelle fission GO:0048285 170 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
g protein coupled receptor signaling pathway GO:0007186 243 0.042
stem cell differentiation GO:0048863 268 0.042
morphogenesis of embryonic epithelium GO:0016331 159 0.042
nuclear division GO:0000280 158 0.042
regulation of angiogenesis GO:0045765 81 0.042
maternal determination of anterior posterior axis embryo GO:0008358 2 0.042
regulation of myeloid cell differentiation GO:0045637 96 0.042
neurotransmitter transport GO:0006836 76 0.041
regulation of ras protein signal transduction GO:0046578 114 0.041
proteasomal protein catabolic process GO:0010498 98 0.041
multicellular organismal response to stress GO:0033555 62 0.040
dephosphorylation GO:0016311 129 0.040
cellular response to peptide GO:1901653 92 0.040
Human
protein localization to membrane GO:0072657 108 0.040
oocyte axis specification GO:0007309 2 0.040
ubiquitin dependent protein catabolic process GO:0006511 129 0.040
protein catabolic process GO:0030163 221 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
negative regulation of neuron apoptotic process GO:0043524 92 0.039
peptidyl threonine phosphorylation GO:0018107 31 0.039
peptidyl serine phosphorylation GO:0018105 74 0.039
regulation of phospholipid translocation GO:0061091 2 0.039
neuron apoptotic process GO:0051402 142 0.038
negative regulation of molecular function GO:0044092 258 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
megakaryocyte differentiation GO:0030219 26 0.038
regulation of purine nucleotide metabolic process GO:1900542 169 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
digestive tract development GO:0048565 190 0.037
regulation of membrane potential GO:0042391 192 0.037
lipid transport GO:0006869 98 0.037
gland development GO:0048732 330 0.037
cation transmembrane transport GO:0098655 266 0.037
endocytosis GO:0006897 168 0.037
ossification involved in bone maturation GO:0043931 12 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
anatomical structure homeostasis GO:0060249 145 0.037
vesicle localization GO:0051648 86 0.037
epithelial tube morphogenesis GO:0060562 303 0.037
blood circulation GO:0008015 195 0.037
microtubule based transport GO:0010970 50 0.037
lipid localization GO:0010876 126 0.037
regulation of synaptic plasticity GO:0048167 87 0.037
guanosine containing compound catabolic process GO:1901069 144 0.036
cranial nerve morphogenesis GO:0021602 26 0.036
cellular response to ammonium ion GO:0071242 2 0.036
striated muscle cell development GO:0055002 125 0.036
positive regulation of cell death GO:0010942 224 0.035
organelle localization GO:0051640 179 0.035
neuron death GO:0070997 154 0.035
tube formation GO:0035148 140 0.035
regulation of hormone levels GO:0010817 211 0.035
regulation of stress fiber assembly GO:0051492 15 0.035
hemostasis GO:0007599 78 0.035
response to inactivity GO:0014854 4 0.035
somitogenesis GO:0001756 69 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
positive regulation of gtp catabolic process GO:0033126 85 0.034
response to light stimulus GO:0009416 135 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.034
spermatid development GO:0007286 108 0.034
branchiomotor neuron axon guidance GO:0021785 7 0.034
neural precursor cell proliferation GO:0061351 121 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
digestive tract morphogenesis GO:0048546 147 0.034
wound healing GO:0042060 157 0.033
ral protein signal transduction GO:0032484 2 0.033
heart process GO:0003015 94 0.033
sympathetic neuron projection extension GO:0097490 4 0.033
response to alkaloid GO:0043279 34 0.033
positive regulation of proteolysis GO:0045862 85 0.033
positive regulation of nucleoside metabolic process GO:0045979 91 0.033
reflex GO:0060004 22 0.033
response to growth factor GO:0070848 198 0.033
locomotory behavior GO:0007626 195 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
positive regulation of actin filament bundle assembly GO:0032233 11 0.032
substrate dependent cell migration GO:0006929 18 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
exocytosis GO:0006887 121 0.032
oocyte anterior posterior axis specification GO:0007314 2 0.032
glossopharyngeal nerve morphogenesis GO:0021615 4 0.032
positive regulation of cell projection organization GO:0031346 95 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.031
retina development in camera type eye GO:0060041 119 0.031
response to ammonium ion GO:0060359 21 0.031
multi multicellular organism process GO:0044706 109 0.031
protein localization to nucleus GO:0034504 121 0.031
sympathetic neuron projection guidance GO:0097491 4 0.031
positive regulation of stress fiber assembly GO:0051496 9 0.031
lamellipodium organization GO:0097581 29 0.031
regulation of protein kinase activity GO:0045859 232 0.030
protein targeting GO:0006605 143 0.030
cell division GO:0051301 120 0.030
defecation GO:0030421 1 0.030
nitrogen compound transport GO:0071705 271 0.030
negative regulation of osteoblast proliferation GO:0033689 4 0.030
developmental growth involved in morphogenesis GO:0060560 138 0.030
response to peptide GO:1901652 136 0.030
Human
endomembrane system organization GO:0010256 147 0.030
circulatory system process GO:0003013 197 0.030
cellular lipid metabolic process GO:0044255 323 0.029
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.029
regulation of nucleotide catabolic process GO:0030811 122 0.029
body morphogenesis GO:0010171 45 0.029
regulation of muscle contraction GO:0006937 49 0.029
translation GO:0006412 93 0.029
carbohydrate metabolic process GO:0005975 230 0.029
cell matrix adhesion GO:0007160 68 0.029
regulation of secretion by cell GO:1903530 249 0.029
rac protein signal transduction GO:0016601 13 0.029
calcium mediated signaling GO:0019722 46 0.028
peptidyl threonine modification GO:0018210 31 0.028
jnk cascade GO:0007254 72 0.028
ear morphogenesis GO:0042471 118 0.028
actin filament polymerization GO:0030041 44 0.028
peptidyl lysine modification GO:0018205 77 0.028
muscle cell development GO:0055001 133 0.028
glial cell differentiation GO:0010001 131 0.028
regulation of homeostatic process GO:0032844 182 0.028
cardiac muscle tissue development GO:0048738 130 0.028
regulation of actin filament based process GO:0032970 99 0.028
cell cell junction assembly GO:0007043 27 0.028
pole plasm assembly GO:0007315 2 0.028
inner ear morphogenesis GO:0042472 101 0.027
regulation of synaptic vesicle transport GO:1902803 13 0.027
heart contraction GO:0060047 93 0.027
regulation of body fluid levels GO:0050878 162 0.027
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.027
regulation of intracellular transport GO:0032386 159 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
membrane tubulation GO:0097320 4 0.027
oocyte construction GO:0007308 2 0.027
regulation of protein catabolic process GO:0042176 108 0.027
oogenesis GO:0048477 56 0.027
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.027
establishment of mitochondrion localization GO:0051654 4 0.027
inner ear receptor cell differentiation GO:0060113 61 0.026
positive regulation of cell activation GO:0050867 158 0.026
synapse organization GO:0050808 125 0.026
chromatin modification GO:0016568 187 0.026
negative regulation of glycolytic process GO:0045820 4 0.026
response to drug GO:0042493 75 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.026
negative regulation of cell motility GO:2000146 61 0.026
b 1 b cell homeostasis GO:0001922 4 0.026
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.025
heart morphogenesis GO:0003007 178 0.025
regulation of synaptic vesicle exocytosis GO:2000300 11 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
apoptotic mitochondrial changes GO:0008637 48 0.025
extracellular matrix organization GO:0030198 147 0.025
regulation of cellular response to stress GO:0080135 159 0.025
positive regulation of vesicle fusion GO:0031340 2 0.025
cellular protein complex assembly GO:0043623 116 0.025
regulation of transmembrane transport GO:0034762 128 0.025
neuromuscular process GO:0050905 99 0.025
substrate adhesion dependent cell spreading GO:0034446 30 0.025
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.025
regulation of alpha beta t cell differentiation GO:0046637 35 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
Human
wnt signaling pathway GO:0016055 188 0.025
regulation of cell activation GO:0050865 289 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
amino acid transport GO:0006865 61 0.025
histone modification GO:0016570 159 0.025
cation transport GO:0006812 399 0.024
positive regulation of protein complex assembly GO:0031334 45 0.024
cation homeostasis GO:0055080 212 0.024
negative regulation of nervous system development GO:0051961 156 0.024
cytoskeleton dependent intracellular transport GO:0030705 50 0.024
photoreceptor cell differentiation GO:0046530 52 0.024
lipid biosynthetic process GO:0008610 179 0.024
cranial nerve development GO:0021545 41 0.024
peptidyl serine modification GO:0018209 83 0.024
cellular ion homeostasis GO:0006873 165 0.024
regulation of tight junction assembly GO:2000810 2 0.024
ossification GO:0001503 216 0.024
negative regulation of cellular component organization GO:0051129 194 0.023
Human
regulation of ral protein signal transduction GO:0032485 4 0.023
mechanoreceptor differentiation GO:0042490 67 0.023
actin cytoskeleton reorganization GO:0031532 21 0.023
cell recognition GO:0008037 83 0.023
atp catabolic process GO:0006200 55 0.023
regulation of protein processing GO:0070613 96 0.023
vagus nerve development GO:0021564 3 0.023
regulation of protein binding GO:0043393 60 0.022
spindle assembly involved in mitosis GO:0090307 4 0.022
covalent chromatin modification GO:0016569 163 0.022
mesodermal cell migration GO:0008078 4 0.022
asymmetric neuroblast division GO:0055059 1 0.022
epithelial tube formation GO:0072175 130 0.022
neuron projection extension GO:1990138 64 0.022
ear development GO:0043583 200 0.022
cellular response to lipid GO:0071396 145 0.022
synaptic vesicle exocytosis GO:0016079 26 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
phosphatidic acid biosynthetic process GO:0006654 2 0.022
engulfment of apoptotic cell GO:0043652 3 0.022
plasma membrane organization GO:0007009 90 0.021
negative regulation of neurotransmitter secretion GO:0046929 5 0.021
regulation of endopeptidase activity GO:0052548 89 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
synaptic transmission gabaergic GO:0051932 19 0.021
dendritic spine maintenance GO:0097062 4 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
forebrain development GO:0030900 302 0.021
regulation of neural precursor cell proliferation GO:2000177 70 0.021
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
Human
epithelial cell development GO:0002064 159 0.021
establishment of protein localization to membrane GO:0090150 54 0.021
regulation of endocytosis GO:0030100 69 0.021
amide transport GO:0042886 138 0.021
eye photoreceptor cell differentiation GO:0001754 41 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
protein localization to endosome GO:0036010 2 0.021
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.021
glandular epithelial cell maturation GO:0002071 2 0.021
regulation of actin filament bundle assembly GO:0032231 18 0.021
definitive hemopoiesis GO:0060216 20 0.020
purine nucleoside monophosphate catabolic process GO:0009128 58 0.020
positive regulation of necrotic cell death GO:0010940 1 0.020
eye photoreceptor cell development GO:0042462 31 0.020
mitotic cytokinesis GO:0000281 4 0.020
golgi to endosome transport GO:0006895 3 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
cerebral cortex cell migration GO:0021795 44 0.020
regulation of osteoblast proliferation GO:0033688 15 0.020
regulation of muscle system process GO:0090257 80 0.020
protein modification by small protein removal GO:0070646 21 0.020
positive regulation of protein catabolic process GO:0045732 60 0.020
positive regulation of cell motility GO:2000147 116 0.020
regulation of cell adhesion GO:0030155 154 0.020
homotypic cell cell adhesion GO:0034109 28 0.020
single fertilization GO:0007338 82 0.020
sensory perception of chemical stimulus GO:0007606 51 0.020
positive regulation of mapk cascade GO:0043410 170 0.019
response to peptide hormone GO:0043434 127 0.019
protein kinase b signaling GO:0043491 74 0.019
positive regulation of glutamate secretion GO:0014049 2 0.019
myofibril assembly GO:0030239 34 0.019
myeloid leukocyte migration GO:0097529 57 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.019

Arhgef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
organ system cancer DOID:0050686 0 0.019