Mus musculus

0 known processes

Atp2a1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

(Aliases: SERCA1)

Atp2a1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
muscle cell development GO:0055001 133 0.971
Worm
muscle cell differentiation GO:0042692 261 0.895
Worm
muscle system process GO:0003012 141 0.833
Human Zebrafish Mouse
muscle fiber development GO:0048747 76 0.816
striated muscle myosin thick filament assembly GO:0071688 1 0.807
Worm
striated muscle tissue development GO:0014706 293 0.806
skeletal muscle organ development GO:0060538 163 0.785
striated muscle contraction GO:0006941 45 0.757
Human
regulation of system process GO:0044057 200 0.747
Human Zebrafish Mouse
muscle contraction GO:0006936 101 0.742
Human Zebrafish
sarcomere organization GO:0045214 24 0.709
muscle tissue development GO:0060537 308 0.688
skeletal muscle fiber development GO:0048741 58 0.553
actin cytoskeleton organization GO:0030036 220 0.552
Worm
transition between fast and slow fiber GO:0014883 9 0.551
Mouse
myosin filament assembly GO:0031034 2 0.542
Worm
striated muscle cell development GO:0055002 125 0.537
Worm
myosin filament organization GO:0031033 3 0.493
Worm
regulation of muscle adaptation GO:0043502 31 0.490
Mouse
skeletal muscle adaptation GO:0043501 16 0.488
Mouse
cellular chemical homeostasis GO:0055082 215 0.479
Human Zebrafish Mouse Worm Fly
ion transmembrane transport GO:0034220 361 0.448
Human Mouse Worm Fly
myotube differentiation GO:0014902 105 0.431
regulation of ion transport GO:0043269 215 0.401
Fly
actomyosin structure organization GO:0031032 56 0.393
Worm
cellular component assembly involved in morphogenesis GO:0010927 139 0.368
Worm
actin filament based movement GO:0030048 23 0.341
cardiac muscle contraction GO:0060048 32 0.336
heart contraction GO:0060047 93 0.327
Mouse Fly
response to inactivity GO:0014854 4 0.324
circulatory system process GO:0003013 197 0.320
Mouse Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.317
Human Mouse Worm Fly
purine containing compound catabolic process GO:0072523 213 0.317
Human Mouse Worm Fly
blood circulation GO:0008015 195 0.305
Mouse Fly
myotube cell development GO:0014904 60 0.277
regulation of skeletal muscle adaptation GO:0014733 12 0.266
Mouse
cardiac muscle cell development GO:0055013 39 0.261
myofibril assembly GO:0030239 34 0.251
Worm
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.251
muscle adaptation GO:0043500 39 0.251
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.242
molting cycle GO:0042303 90 0.230
Worm
cardiac muscle tissue development GO:0048738 130 0.227
ribose phosphate metabolic process GO:0019693 291 0.221
Human Mouse Worm Fly
regulation of transmembrane transport GO:0034762 128 0.213
Fly
regulation of striated muscle contraction GO:0006942 25 0.211
Human
skeletal myofibril assembly GO:0014866 4 0.191
regulation of skeletal muscle fiber development GO:0048742 36 0.185
purine ribonucleotide metabolic process GO:0009150 290 0.181
Human Mouse Worm Fly
ribonucleoside monophosphate catabolic process GO:0009158 57 0.178
Human Mouse Worm Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.177
Fly
purine nucleoside monophosphate catabolic process GO:0009128 58 0.177
Human Mouse Worm Fly
limb morphogenesis GO:0035108 149 0.174
canonical wnt signaling pathway GO:0060070 130 0.163
cellular response to cytokine stimulus GO:0071345 189 0.158
wnt signaling pathway GO:0016055 188 0.157
transmembrane transport GO:0055085 412 0.157
Human Mouse Worm Fly
regulation of atp catabolic process GO:1903289 9 0.152
Fly
hair follicle development GO:0001942 85 0.152
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.151
Human Mouse Worm Fly
regulation of membrane potential GO:0042391 192 0.149
Fly
regulation of heart contraction GO:0008016 77 0.149
Mouse
synaptic transmission GO:0007268 329 0.145
Mouse Fly
negative regulation of protein modification process GO:0031400 163 0.144
regulation of feeding behavior GO:0060259 3 0.143
calcium ion homeostasis GO:0055074 127 0.137
Human Zebrafish Mouse Worm Fly
divalent inorganic cation transport GO:0072511 178 0.136
Human Mouse Worm Fly
cellular metal ion homeostasis GO:0006875 151 0.134
Human Zebrafish Mouse Worm Fly
purine nucleoside metabolic process GO:0042278 241 0.133
Human Mouse Worm Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.131
Human Mouse Worm Fly
regulation of sarcomere organization GO:0060297 4 0.126
regulation of skeletal muscle contraction GO:0014819 3 0.122
Human
intermediate filament organization GO:0045109 15 0.122
heart morphogenesis GO:0003007 178 0.119
purine nucleotide metabolic process GO:0006163 302 0.117
Human Mouse Worm Fly
regulation of atp metabolic process GO:1903578 17 0.117
Fly
skeletal muscle thin filament assembly GO:0030240 2 0.116
regulation of heart rate GO:0002027 36 0.116
fatty acid metabolic process GO:0006631 121 0.114
Fly
atp metabolic process GO:0046034 75 0.112
Human Mouse Worm Fly
actin mediated cell contraction GO:0070252 15 0.111
cellular nitrogen compound catabolic process GO:0044270 280 0.110
Human Mouse Worm Fly
skin development GO:0043588 220 0.108
somite development GO:0061053 81 0.105
inflammatory response GO:0006954 244 0.105
negative regulation of cellular protein metabolic process GO:0032269 247 0.104
purine nucleoside triphosphate metabolic process GO:0009144 226 0.101
Human Mouse Worm Fly
calcium ion transport GO:0006816 159 0.097
Human Mouse Worm Fly
cardiac muscle tissue morphogenesis GO:0055008 44 0.096
cellular ion homeostasis GO:0006873 165 0.096
Human Zebrafish Mouse Worm Fly
extraocular skeletal muscle development GO:0002074 2 0.096
regulation of nucleotide catabolic process GO:0030811 122 0.094
Fly
regulation of nucleoside metabolic process GO:0009118 130 0.093
Fly
metal ion homeostasis GO:0055065 189 0.092
Human Zebrafish Mouse Worm Fly
cardiac muscle cell differentiation GO:0055007 69 0.092
bmp signaling pathway GO:0030509 93 0.089
hair follicle morphogenesis GO:0031069 29 0.089
ribonucleoside catabolic process GO:0042454 206 0.088
Human Mouse Worm Fly
glycosyl compound catabolic process GO:1901658 206 0.087
Human Mouse Worm Fly
nucleoside phosphate metabolic process GO:0006753 338 0.087
Human Mouse Worm Fly
aromatic compound catabolic process GO:0019439 286 0.087
Human Mouse Worm Fly
purine containing compound metabolic process GO:0072521 311 0.087
Human Mouse Worm Fly
inorganic cation transmembrane transport GO:0098662 207 0.086
Human Mouse Worm Fly
regulation of myotube differentiation GO:0010830 62 0.085
hair cycle GO:0042633 90 0.084
endodermal cell fate specification GO:0001714 4 0.083
organelle assembly GO:0070925 177 0.082
Worm
heterocycle catabolic process GO:0046700 280 0.082
Human Mouse Worm Fly
regulation of response to wounding GO:1903034 189 0.081
cardiac myofibril assembly GO:0055003 12 0.081
inorganic ion transmembrane transport GO:0098660 234 0.081
Human Mouse Worm Fly
actin myosin filament sliding GO:0033275 1 0.080
cellular lipid metabolic process GO:0044255 323 0.080
Fly
cardiac cell development GO:0055006 41 0.079
carbohydrate derivative catabolic process GO:1901136 231 0.079
Human Mouse Worm Fly
cellular ketone metabolic process GO:0042180 84 0.078
intermediate filament based process GO:0045103 27 0.078
regulation of the force of heart contraction GO:0002026 17 0.077
Mouse
regulation of muscle system process GO:0090257 80 0.077
Human Zebrafish Mouse
regulation of blood circulation GO:1903522 93 0.077
Mouse
regulation of atpase activity GO:0043462 9 0.075
Fly
regulation of actin filament based process GO:0032970 99 0.075
glycosyl compound metabolic process GO:1901657 246 0.074
Human Mouse Worm Fly
muscle atrophy GO:0014889 3 0.074
regulation of ion transmembrane transport GO:0034765 119 0.072
Fly
ribonucleotide metabolic process GO:0009259 291 0.072
Human Mouse Worm Fly
purine nucleoside catabolic process GO:0006152 205 0.072
Human Mouse Worm Fly
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.070
organonitrogen compound catabolic process GO:1901565 264 0.070
Human Mouse Worm Fly
cation transport GO:0006812 399 0.070
Human Mouse Worm Fly
regulation of wnt signaling pathway GO:0030111 123 0.069
regulation of neuron differentiation GO:0045664 281 0.069
sensory organ morphogenesis GO:0090596 242 0.067
acetylcholine transport GO:0015870 2 0.067
skeletal muscle fiber adaptation GO:0043503 1 0.065
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.064
peripheral nervous system axon regeneration GO:0014012 2 0.064
sa node cell action potential GO:0086015 4 0.063
neurotransmitter transport GO:0006836 76 0.063
Mouse
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.062
cellular amine metabolic process GO:0044106 44 0.061
heart process GO:0003015 94 0.061
Mouse Fly
circadian sleep wake cycle rem sleep GO:0042747 1 0.061
regulation of ion transmembrane transporter activity GO:0032412 54 0.060
Fly
extrinsic apoptotic signaling pathway GO:0097191 126 0.060
myotube differentiation involved in skeletal muscle regeneration GO:0014908 2 0.060
muscle filament sliding GO:0030049 1 0.059
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.059
Human Mouse Worm Fly
regionalization GO:0003002 337 0.059
type b pancreatic cell proliferation GO:0044342 10 0.058
extracellular structure organization GO:0043062 148 0.058
cellular homeostasis GO:0019725 240 0.058
Human Zebrafish Mouse Worm Fly
appendage morphogenesis GO:0035107 149 0.056
nucleotide metabolic process GO:0009117 332 0.056
Human Mouse Worm Fly
sequestering of calcium ion GO:0051208 18 0.055
Fly
cation transmembrane transport GO:0098655 266 0.055
Human Mouse Worm Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.054
Human Mouse Worm Fly
regulation of muscle contraction GO:0006937 49 0.054
Human Zebrafish
embryonic limb morphogenesis GO:0030326 126 0.053
atp catabolic process GO:0006200 55 0.052
Human Mouse Worm Fly
regulation of intracellular transport GO:0032386 159 0.052
nucleoside triphosphate metabolic process GO:0009141 230 0.052
Human Mouse Worm Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.051
Human Mouse Worm Fly
intermediate filament cytoskeleton organization GO:0045104 26 0.051
cytokine mediated signaling pathway GO:0019221 115 0.051
cell fate commitment GO:0045165 210 0.050
appendage development GO:0048736 166 0.050
cell type specific apoptotic process GO:0097285 268 0.050
striated muscle adaptation GO:0014888 26 0.050
Mouse
regulation of myoblast differentiation GO:0045661 29 0.050
oxidation reduction process GO:0055114 342 0.049
Fly
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.049
skeletal muscle cell differentiation GO:0035914 66 0.049
sodium ion export from cell GO:0036376 1 0.049
somitogenesis GO:0001756 69 0.049
ribonucleoside triphosphate catabolic process GO:0009203 199 0.049
Human Mouse Worm Fly
purine ribonucleotide catabolic process GO:0009154 208 0.048
Human Mouse Worm Fly
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
Human Zebrafish Mouse Worm Fly
leukocyte differentiation GO:0002521 342 0.047
lipid biosynthetic process GO:0008610 179 0.047
Fly
purine nucleotide catabolic process GO:0006195 211 0.046
Human Mouse Worm Fly
regulation of body fluid levels GO:0050878 162 0.046
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.045
response to inorganic substance GO:0010035 96 0.045
negative regulation of response to wounding GO:1903035 77 0.045
lateral geniculate nucleus development GO:0021771 1 0.044
regulation of muscle tissue development GO:1901861 97 0.044
nucleoside metabolic process GO:0009116 246 0.044
Human Mouse Worm Fly
nucleoside phosphate catabolic process GO:1901292 222 0.043
Human Mouse Worm Fly
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.043
acetylcholine secretion neurotransmission GO:0014055 2 0.043
sodium ion export GO:0071436 2 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.042
striated muscle atrophy GO:0014891 2 0.042
regulation of hormone levels GO:0010817 211 0.041
negative regulation of molecular function GO:0044092 258 0.041
adult locomotory behavior GO:0008344 91 0.041
Fly
response to muscle stretch GO:0035994 1 0.041
axonogenesis GO:0007409 274 0.040
amine metabolic process GO:0009308 45 0.040
skeletal muscle myosin thick filament assembly GO:0030241 1 0.040
epidermis morphogenesis GO:0048730 33 0.040
gland development GO:0048732 330 0.039
potassium ion transport GO:0006813 52 0.039
nucleoside monophosphate metabolic process GO:0009123 85 0.039
Human Mouse Worm Fly
morphogenesis of a branching structure GO:0001763 203 0.039
ventricular cardiac muscle cell action potential GO:0086005 4 0.038
ribonucleoside metabolic process GO:0009119 245 0.038
Human Mouse Worm Fly
neural tube formation GO:0001841 108 0.038
neuron projection extension GO:1990138 64 0.038
neuron apoptotic process GO:0051402 142 0.038
regulation of transferase activity GO:0051338 263 0.037
regulation of membrane repolarization GO:0060306 7 0.037
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.037
divalent inorganic cation homeostasis GO:0072507 138 0.037
Human Zebrafish Mouse Worm Fly
calcium ion transport into cytosol GO:0060402 48 0.037
regulation of inflammatory response GO:0050727 147 0.036
ossification GO:0001503 216 0.036
acetate ester transport GO:1901374 2 0.036
negative regulation of cell fate specification GO:0009996 4 0.036
protein localization to organelle GO:0033365 185 0.036
negative regulation of organelle organization GO:0010639 90 0.035
actin filament organization GO:0007015 113 0.035
negative regulation of wnt signaling pathway GO:0030178 73 0.035
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.035
regulation of protein binding GO:0043393 60 0.034
nucleoside monophosphate catabolic process GO:0009125 59 0.034
Human Mouse Worm Fly
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.034
cervix development GO:0060067 2 0.034
microtubule based process GO:0007017 236 0.034
response to oxygen levels GO:0070482 62 0.034
submandibular salivary gland formation GO:0060661 1 0.034
regulation of defense response GO:0031347 233 0.034
cardiac muscle fiber development GO:0048739 4 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
Fly
regulation of organelle organization GO:0033043 289 0.034
calcium ion transmembrane transport GO:0070588 85 0.034
Human Mouse Worm Fly
learning or memory GO:0007611 148 0.033
keratinocyte differentiation GO:0030216 48 0.033
peripheral nervous system neuron axonogenesis GO:0048936 3 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
Human Mouse Worm Fly
oxygen homeostasis GO:0032364 2 0.033
nucleoside catabolic process GO:0009164 206 0.033
Human Mouse Worm Fly
cellular modified amino acid biosynthetic process GO:0042398 12 0.032
epidermis development GO:0008544 187 0.032
organophosphate catabolic process GO:0046434 232 0.032
Human Mouse Worm Fly
ribonucleoside monophosphate metabolic process GO:0009161 80 0.032
Human Mouse Worm Fly
body morphogenesis GO:0010171 45 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
Human Mouse Worm Fly
action potential GO:0001508 78 0.032
sodium ion transmembrane transport GO:0035725 49 0.031
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.031
negative regulation of kinase activity GO:0033673 81 0.031
uterus morphogenesis GO:0061038 2 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
regulation of neurotransmitter levels GO:0001505 87 0.031
Mouse
response to muscle inactivity GO:0014870 4 0.031
inositol lipid mediated signaling GO:0048017 41 0.031
lipid modification GO:0030258 65 0.030
Fly
segmentation GO:0035282 93 0.030
limb development GO:0060173 166 0.030
small molecule biosynthetic process GO:0044283 132 0.030
regulation of kinase activity GO:0043549 249 0.030
cytoplasmic transport GO:0016482 234 0.030
hepatocyte apoptotic process GO:0097284 11 0.030
cation homeostasis GO:0055080 212 0.029
Human Zebrafish Mouse Worm Fly
tongue development GO:0043586 18 0.029
response to activity GO:0014823 13 0.029
regulation of circadian sleep wake cycle GO:0042749 3 0.029
skeletal system development GO:0001501 356 0.029
tissue regeneration GO:0042246 22 0.029
purine nucleoside monophosphate metabolic process GO:0009126 81 0.029
Human Mouse Worm Fly
multicellular organismal signaling GO:0035637 91 0.028
regulation of blood pressure GO:0008217 93 0.028
microtubule cytoskeleton organization GO:0000226 157 0.028
conditioned taste aversion GO:0001661 4 0.028
embryonic skeletal system morphogenesis GO:0048704 91 0.028
second messenger mediated signaling GO:0019932 73 0.028
maintenance of location GO:0051235 89 0.028
Human Fly
intermediate filament bundle assembly GO:0045110 3 0.028
cytosolic calcium ion transport GO:0060401 48 0.027
developmental maturation GO:0021700 193 0.027
cardiac muscle cell contraction GO:0086003 7 0.027
norepinephrine transport GO:0015874 2 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
Fly
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.027
neural precursor cell proliferation GO:0061351 121 0.027
embryonic appendage morphogenesis GO:0035113 126 0.027
regulation of canonical wnt signaling pathway GO:0060828 82 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
myeloid cell differentiation GO:0030099 233 0.026
regulation of cytoplasmic transport GO:1903649 112 0.026
regulation of actin cytoskeleton organization GO:0032956 84 0.026
regulation of protein localization GO:0032880 231 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.026
divalent metal ion transport GO:0070838 172 0.025
Human Mouse Worm Fly
somite specification GO:0001757 4 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 2 0.025
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.025
membrane depolarization GO:0051899 64 0.025
tube formation GO:0035148 140 0.025
syncytium formation GO:0006949 43 0.024
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.024
regulation of blood vessel size GO:0050880 56 0.024
calcium mediated signaling GO:0019722 46 0.024
positive regulation of vasoconstriction GO:0045907 4 0.024
sensory perception GO:0007600 245 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
Fly
positive regulation of skeletal muscle fiber development GO:0048743 3 0.024
epithelial cell proliferation GO:0050673 174 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
metanephric loop of henle development GO:0072236 4 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of cysteine type endopeptidase activity GO:2000116 65 0.023
neuromuscular process GO:0050905 99 0.023
cellular response to metal ion GO:0071248 31 0.023
peptidyl amino acid modification GO:0018193 336 0.023
detection of external stimulus GO:0009581 61 0.023
release of sequestered calcium ion into cytosol GO:0051209 42 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
Human Mouse Worm Fly
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.023
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.023
carbohydrate homeostasis GO:0033500 128 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
phospholipid metabolic process GO:0006644 87 0.023
glycerophospholipid metabolic process GO:0006650 71 0.023
regulation of striated muscle cell differentiation GO:0051153 81 0.022
homeostasis of number of cells GO:0048872 210 0.022
Fly
regulation of myoblast proliferation GO:2000291 8 0.022
regulation of ion homeostasis GO:2000021 64 0.022
Fly
reproductive behavior GO:0019098 32 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
multicellular organismal water homeostasis GO:0050891 23 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
cardiac chamber development GO:0003205 108 0.022
myeloid cell homeostasis GO:0002262 114 0.022
gpi anchor metabolic process GO:0006505 7 0.022
negative regulation of transferase activity GO:0051348 85 0.022
tube closure GO:0060606 91 0.021
behavioral response to nutrient GO:0051780 1 0.021
norepinephrine secretion GO:0048243 2 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
Human Zebrafish Mouse Worm Fly
negative regulation of gastrulation GO:2000542 3 0.021
cell division GO:0051301 120 0.021
negative regulation of epithelial cell proliferation GO:0050680 64 0.021
response to extracellular stimulus GO:0009991 127 0.021
Worm
protein processing GO:0016485 163 0.021
regulation of interleukin 8 secretion GO:2000482 2 0.021
skin morphogenesis GO:0043589 38 0.021
cell junction organization GO:0034330 77 0.021
regulation of calcium ion transport into cytosol GO:0010522 31 0.021
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.021
positive regulation of glial cell proliferation GO:0060252 4 0.021
gas homeostasis GO:0033483 3 0.020
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.020
endodermal digestive tract morphogenesis GO:0061031 4 0.020
hindbrain development GO:0030902 128 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
granulocyte differentiation GO:0030851 17 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
Human Mouse Worm Fly
ras protein signal transduction GO:0007265 77 0.020
camera type eye development GO:0043010 266 0.020
renal vesicle induction GO:0072034 3 0.020
organ growth GO:0035265 117 0.020
detection of muscle stretch GO:0035995 1 0.019
regulation of morphogenesis of a branching structure GO:0060688 53 0.019
rna processing GO:0006396 105 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
Fly
regulation of neuron projection development GO:0010975 169 0.019
positive regulation of cell cycle process GO:0090068 61 0.019
regulation of calcium ion transport GO:0051924 69 0.019
Fly
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.019
regulation of proteolysis GO:0030162 164 0.019
extracellular matrix organization GO:0030198 147 0.019
anatomical structure homeostasis GO:0060249 145 0.019
cell communication involved in cardiac conduction GO:0086065 9 0.019
hepatic duct development GO:0061011 1 0.019
myoblast differentiation GO:0045445 52 0.019
negative regulation of proteolysis GO:0045861 74 0.019
ventricular cardiac myofibril assembly GO:0055005 3 0.019
positive regulation of muscle adaptation GO:0014744 2 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
microglial cell activation GO:0001774 3 0.019
regulation of protein kinase activity GO:0045859 232 0.019
relaxation of muscle GO:0090075 18 0.019
Human
covalent chromatin modification GO:0016569 163 0.018
cell proliferation in forebrain GO:0021846 30 0.018
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.018
positive regulation of interleukin 8 secretion GO:2000484 1 0.018
glycerolipid metabolic process GO:0046486 122 0.018
nephric duct formation GO:0072179 4 0.018
regulation of protein processing GO:0070613 96 0.018
regeneration GO:0031099 38 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
organic hydroxy compound biosynthetic process GO:1901617 77 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.018
water homeostasis GO:0030104 27 0.018
Worm
nucleotide catabolic process GO:0009166 217 0.018
Human Mouse Worm Fly
embryonic epithelial tube formation GO:0001838 130 0.018
developmental cell growth GO:0048588 84 0.018
cellular response to inorganic substance GO:0071241 37 0.018
neural tube closure GO:0001843 90 0.018
wound healing GO:0042060 157 0.018
sequestering of metal ion GO:0051238 19 0.018
Fly
regulation of cardiac muscle contraction GO:0055117 21 0.018
nuclear division GO:0000280 158 0.018
neuron death GO:0070997 154 0.018
ventricular cardiac muscle tissue development GO:0003229 38 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.018
dna metabolic process GO:0006259 303 0.017
fat cell differentiation GO:0045444 160 0.017
peptidyl serine modification GO:0018209 83 0.017
vascular process in circulatory system GO:0003018 62 0.017
regulation of heart growth GO:0060420 31 0.017
regulation of actin filament based movement GO:1903115 12 0.017
regulation of transporter activity GO:0032409 57 0.017
Fly
detection of stimulus GO:0051606 84 0.017
glucose homeostasis GO:0042593 128 0.017
positive regulation of growth GO:0045927 104 0.017
regulation of systemic arterial blood pressure GO:0003073 61 0.017
negative regulation of immune system process GO:0002683 209 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of cell cycle process GO:0010564 160 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
Human Mouse Worm Fly
cell activation involved in immune response GO:0002263 126 0.017
response to organonitrogen compound GO:0010243 246 0.017
central nervous system morphogenesis GO:0021551 2 0.017
multi multicellular organism process GO:0044706 109 0.017
regulation of organ growth GO:0046620 61 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
positive regulation of cell development GO:0010720 237 0.016
negative regulation of action potential GO:0045759 1 0.016
multi organism behavior GO:0051705 62 0.016
musculoskeletal movement GO:0050881 16 0.016
Human
positive regulation of calcium ion transport GO:0051928 27 0.016
Fly
columnar cuboidal epithelial cell maturation GO:0002069 4 0.016
positive regulation of dopamine secretion GO:0033603 2 0.016
outer medullary collecting duct development GO:0072060 1 0.016
regulation of norepinephrine secretion GO:0014061 2 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of water loss via skin GO:0033561 16 0.016
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
response to stimulus involved in regulation of muscle adaptation GO:0014874 6 0.016
membrane lipid biosynthetic process GO:0046467 32 0.016
positive regulation of protein modification process GO:0031401 299 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
Human Mouse Worm Fly
negative regulation of inflammatory response GO:0050728 61 0.016
generation of ovulation cycle rhythm GO:0060112 1 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
endoplasmic reticulum to cytosol transport GO:1903513 12 0.016
axis elongation involved in somitogenesis GO:0090245 4 0.016
regulation of calcium ion transmembrane transport GO:1903169 20 0.016
Fly
organic anion transport GO:0015711 137 0.015
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
feeding behavior GO:0007631 62 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
cardiocyte differentiation GO:0035051 87 0.015
protein maturation GO:0051604 176 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of homeostatic process GO:0032844 182 0.015
Fly
positive regulation of ion transport GO:0043270 65 0.015
Fly
mesoderm development GO:0007498 100 0.015
membrane lipid metabolic process GO:0006643 53 0.015
sensory perception of sound GO:0007605 97 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
cell proliferation in external granule layer GO:0021924 10 0.015
regulation of binding GO:0051098 111 0.015
regulation of neurotransmitter secretion GO:0046928 29 0.015
Mouse
negative regulation of cell proliferation GO:0008285 296 0.015
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.015
trachea cartilage morphogenesis GO:0060535 4 0.015

Atp2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.656
disease of anatomical entity DOID:7 0 0.656
Human
musculoskeletal system disease DOID:17 0 0.656
muscle tissue disease DOID:66 0 0.617
distal arthrogryposis DOID:0050646 0 0.211
myopathy DOID:423 0 0.044
heart disease DOID:114 0 0.044
cardiomyopathy DOID:0050700 0 0.044
cardiovascular system disease DOID:1287 0 0.044
nervous system disease DOID:863 0 0.023
Human
sensory system disease DOID:0050155 0 0.020
dilated cardiomyopathy DOID:12930 0 0.019
intrinsic cardiomyopathy DOID:0060036 0 0.019
muscular dystrophy DOID:9884 0 0.017
limb girdle muscular dystrophy DOID:11724 0 0.017