Mus musculus

143 known processes

Atp6ap1

ATPase, H+ transporting, lysosomal accessory protein 1

(Aliases: Atp6ip1,VATPS1,AC45,FLJ00383,mFLJ00383,16A,Atp6s1,C7-1,AW108110,XAP-3,AI316502,CF2)

Atp6ap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.358
transmembrane transport GO:0055085 412 0.294
cation transport GO:0006812 399 0.294
sphingolipid metabolic process GO:0006665 45 0.269
regulation of angiotensin levels in blood GO:0002002 4 0.225
inorganic cation transmembrane transport GO:0098662 207 0.219
hydrogen ion transmembrane transport GO:1902600 25 0.178
cation transmembrane transport GO:0098655 266 0.154
inorganic ion transmembrane transport GO:0098660 234 0.151
divalent inorganic cation transport GO:0072511 178 0.120
organonitrogen compound catabolic process GO:1901565 264 0.113
membrane lipid biosynthetic process GO:0046467 32 0.108
sphingolipid biosynthetic process GO:0030148 26 0.106
pigmentation GO:0043473 71 0.098
Zebrafish
cellular lipid metabolic process GO:0044255 323 0.097
ceramide metabolic process GO:0006672 31 0.094
carbohydrate derivative catabolic process GO:1901136 231 0.092
proton transport GO:0015992 35 0.092
notochord cell development GO:0060035 1 0.085
positive regulation of necrotic cell death GO:0010940 1 0.084
ceramide biosynthetic process GO:0046513 20 0.083
vacuole organization GO:0007033 38 0.082
organelle assembly GO:0070925 177 0.076
lipid biosynthetic process GO:0008610 179 0.075
membrane lipid metabolic process GO:0006643 53 0.074
intracellular protein transport GO:0006886 204 0.061
endocytosis GO:0006897 168 0.061
Worm
metal ion homeostasis GO:0055065 189 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.057
nucleoside monophosphate metabolic process GO:0009123 85 0.057
calcium ion transport GO:0006816 159 0.056
apoptotic signaling pathway GO:0097190 306 0.054
regulation of angiotensin metabolic process GO:0060177 4 0.053
lysosome organization GO:0007040 21 0.050
nucleotide metabolic process GO:0009117 332 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.048
rna interference GO:0016246 2 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
lateral line system development GO:0048925 1 0.044
ribonucleoside monophosphate catabolic process GO:0009158 57 0.043
cellular amino acid metabolic process GO:0006520 103 0.042
organophosphate catabolic process GO:0046434 232 0.041
amine metabolic process GO:0009308 45 0.040
cellular homeostasis GO:0019725 240 0.040
divalent metal ion transport GO:0070838 172 0.040
positive regulation of programmed cell death GO:0043068 218 0.039
positive regulation of wnt signaling pathway GO:0030177 45 0.039
regulation of mapk cascade GO:0043408 248 0.039
peptide metabolic process GO:0006518 46 0.039
regionalization GO:0003002 337 0.038
regulation of transferase activity GO:0051338 263 0.037
regulation of wnt signaling pathway GO:0030111 123 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
heterocycle catabolic process GO:0046700 280 0.036
calcium ion transmembrane transport GO:0070588 85 0.036
aromatic compound catabolic process GO:0019439 286 0.035
nucleoside monophosphate catabolic process GO:0009125 59 0.035
purine nucleoside metabolic process GO:0042278 241 0.034
phospholipid metabolic process GO:0006644 87 0.033
cellular amine metabolic process GO:0044106 44 0.033
macromolecule catabolic process GO:0009057 281 0.033
cellular component assembly involved in morphogenesis GO:0010927 139 0.033
ribonucleoside monophosphate metabolic process GO:0009161 80 0.033
camera type eye development GO:0043010 266 0.033
Zebrafish
sensory perception GO:0007600 245 0.031
calcium ion homeostasis GO:0055074 127 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
hydrogen transport GO:0006818 35 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.031
gland development GO:0048732 330 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
wnt signaling pathway GO:0016055 188 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
locomotory behavior GO:0007626 195 0.029
anion transport GO:0006820 177 0.029
cellular amide metabolic process GO:0043603 58 0.029
retina development in camera type eye GO:0060041 119 0.029
Zebrafish
purine ribonucleoside catabolic process GO:0046130 205 0.029
purine nucleoside catabolic process GO:0006152 205 0.028
atp catabolic process GO:0006200 55 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
neuromuscular process controlling balance GO:0050885 59 0.028
sensory system development GO:0048880 3 0.027
neuronal action potential GO:0019228 54 0.027
membrane organization GO:0061024 245 0.027
regulation of ion transport GO:0043269 215 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
gonad development GO:0008406 141 0.026
glycolipid metabolic process GO:0006664 25 0.026
protein catabolic process GO:0030163 221 0.026
glycosyl compound catabolic process GO:1901658 206 0.026
divalent inorganic cation homeostasis GO:0072507 138 0.025
cellular ion homeostasis GO:0006873 165 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
astrocyte cell migration GO:0043615 3 0.025
cellular chemical homeostasis GO:0055082 215 0.025
cation homeostasis GO:0055080 212 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
positive regulation of protein modification process GO:0031401 299 0.024
cellular ketone metabolic process GO:0042180 84 0.024
cytoplasmic transport GO:0016482 234 0.024
regulation of membrane potential GO:0042391 192 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
mapk cascade GO:0000165 281 0.023
negative regulation of molecular function GO:0044092 258 0.023
skin development GO:0043588 220 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
circulatory system process GO:0003013 197 0.023
maintenance of location GO:0051235 89 0.022
alcohol metabolic process GO:0006066 116 0.022
atp metabolic process GO:0046034 75 0.022
kidney development GO:0001822 213 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
female gamete generation GO:0007292 74 0.022
retrograde transport endosome to golgi GO:0042147 2 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
rho protein signal transduction GO:0007266 32 0.022
multicellular organismal signaling GO:0035637 91 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
fertilization GO:0009566 127 0.021
developmental maturation GO:0021700 193 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
oligosaccharide catabolic process GO:0009313 2 0.021
purine containing compound metabolic process GO:0072521 311 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
tissue remodeling GO:0048771 102 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
anatomical structure homeostasis GO:0060249 145 0.021
nucleoside metabolic process GO:0009116 246 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
dephosphorylation GO:0016311 129 0.020
transmission of nerve impulse GO:0019226 76 0.020
protein processing GO:0016485 163 0.020
heart morphogenesis GO:0003007 178 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
lytic vacuole organization GO:0080171 21 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
regulation of protein transport GO:0051223 163 0.019
positive regulation of cell activation GO:0050867 158 0.019
lipid localization GO:0010876 126 0.019
intrahepatic bile duct development GO:0035622 2 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
receptor mediated endocytosis GO:0006898 51 0.019
Worm
single fertilization GO:0007338 82 0.019
regulation of systemic arterial blood pressure GO:0003073 61 0.019
purine containing compound catabolic process GO:0072523 213 0.019
epidermis development GO:0008544 187 0.019
regulation of organelle organization GO:0033043 289 0.018
multicellular organism growth GO:0035264 161 0.018
sensory perception of sound GO:0007605 97 0.018
positive regulation of cell death GO:0010942 224 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
regulation of neuron projection development GO:0010975 169 0.018
response to inorganic substance GO:0010035 96 0.018
development of primary sexual characteristics GO:0045137 143 0.018
response to copper ion GO:0046688 3 0.018
glycosphingolipid catabolic process GO:0046479 5 0.018
wound healing GO:0042060 157 0.018
regulation of protein kinase activity GO:0045859 232 0.018
circadian sleep wake cycle rem sleep GO:0042747 1 0.018
retina morphogenesis in camera type eye GO:0060042 45 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
regulation of hormone levels GO:0010817 211 0.018
early endosome to late endosome transport GO:0045022 2 0.018
regulation of transmembrane transport GO:0034762 128 0.018
organic hydroxy compound transport GO:0015850 93 0.017
action potential GO:0001508 78 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
necrotic cell death GO:0070265 30 0.017
aminoglycan metabolic process GO:0006022 34 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
regulation of cell projection organization GO:0031344 206 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
gene silencing by rna GO:0031047 19 0.017
muscle system process GO:0003012 141 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
ketone catabolic process GO:0042182 3 0.017
cellular calcium ion homeostasis GO:0006874 119 0.016
regulation of cell cycle GO:0051726 281 0.016
endomembrane system organization GO:0010256 147 0.016
snare complex disassembly GO:0035494 2 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
ensheathment of neurons GO:0007272 76 0.016
positive regulation of growth GO:0045927 104 0.016
sphingosine metabolic process GO:0006670 4 0.016
hormone metabolic process GO:0042445 86 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
establishment of protein localization to membrane GO:0090150 54 0.016
male courtship behavior GO:0008049 2 0.016
negative regulation of nervous system development GO:0051961 156 0.016
regulation of cellular response to stress GO:0080135 159 0.015
establishment of vesicle localization GO:0051650 81 0.015
protein localization to organelle GO:0033365 185 0.015
potassium ion transport GO:0006813 52 0.015
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.015
liposaccharide metabolic process GO:1903509 27 0.015
exocytosis GO:0006887 121 0.015
small molecule biosynthetic process GO:0044283 132 0.015
cell adhesion GO:0007155 329 0.015
sterol transport GO:0015918 38 0.015
regulation of secretion GO:0051046 274 0.015
organelle localization GO:0051640 179 0.015
regulation of calcium ion transport GO:0051924 69 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
glycosaminoglycan metabolic process GO:0030203 34 0.014
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.014
nucleotide catabolic process GO:0009166 217 0.014
immune effector process GO:0002252 321 0.014
response to oxidative stress GO:0006979 123 0.014
cellular response to oxidative stress GO:0034599 76 0.014
sensory organ morphogenesis GO:0090596 242 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
ceramide catabolic process GO:0046514 7 0.014
signal transduction in absence of ligand GO:0038034 55 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
negative regulation of cell development GO:0010721 169 0.014
inter male aggressive behavior GO:0002121 3 0.014
transition metal ion transport GO:0000041 38 0.014
organic acid biosynthetic process GO:0016053 86 0.014
learning or memory GO:0007611 148 0.014
response to fibroblast growth factor GO:0071774 47 0.014
striated muscle tissue development GO:0014706 293 0.014
blood circulation GO:0008015 195 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cell growth GO:0016049 130 0.013
regulation of blood pressure GO:0008217 93 0.013
molting cycle GO:0042303 90 0.013
Worm
purine nucleotide catabolic process GO:0006195 211 0.013
negative regulation of neuron death GO:1901215 98 0.013
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.013
regulation of cell growth GO:0001558 91 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
stem cell differentiation GO:0048863 268 0.013
germ cell development GO:0007281 185 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
leukocyte mediated immunity GO:0002443 174 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
protein localization to plasma membrane GO:0072659 57 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
phospholipid biosynthetic process GO:0008654 36 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
organic anion transport GO:0015711 137 0.013
neuromuscular process GO:0050905 99 0.013
adult walking behavior GO:0007628 41 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
eye pigmentation GO:0048069 3 0.013
nuclear transport GO:0051169 139 0.012
progesterone metabolic process GO:0042448 4 0.012
establishment of protein localization to plasma membrane GO:0090002 34 0.012
male gamete generation GO:0048232 285 0.012
response to reactive oxygen species GO:0000302 56 0.012
protein localization to endosome GO:0036010 2 0.012
renal system development GO:0072001 225 0.012
interspecies interaction between organisms GO:0044419 83 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
axonogenesis GO:0007409 274 0.012
protein localization to membrane GO:0072657 108 0.012
adult locomotory behavior GO:0008344 91 0.012
sphingolipid catabolic process GO:0030149 7 0.012
regulation of intracellular transport GO:0032386 159 0.012
negative regulation of hormone biosynthetic process GO:0032353 4 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
embryonic heart tube morphogenesis GO:0003143 51 0.012
natural killer cell activation involved in immune response GO:0002323 10 0.012
protein localization to vacuole GO:0072665 4 0.012
regulation of body fluid levels GO:0050878 162 0.012
regulation of circadian sleep wake cycle GO:0042749 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
l ascorbic acid metabolic process GO:0019852 4 0.012
cellular response to thyroid hormone stimulus GO:0097067 1 0.012
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.012
response to radiation GO:0009314 165 0.012
plasma membrane organization GO:0007009 90 0.011
non canonical wnt signaling pathway GO:0035567 33 0.011
extracellular structure organization GO:0043062 148 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of removal of superoxide radicals GO:2000121 4 0.011
amino acid transport GO:0006865 61 0.011
glycerolipid metabolic process GO:0046486 122 0.011
protein targeting GO:0006605 143 0.011
regulation of secretion by cell GO:1903530 249 0.011
gene silencing GO:0016458 38 0.011
axon ensheathment GO:0008366 76 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of monocyte chemotaxis GO:0090025 3 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
lipoprotein biosynthetic process GO:0042158 33 0.011
regulation of kinase activity GO:0043549 249 0.011
ear development GO:0043583 200 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
macroautophagy GO:0016236 21 0.011
negative regulation of multi organism process GO:0043901 68 0.011
regulation of cell activation GO:0050865 289 0.011
sequestering of metal ion GO:0051238 19 0.011
negative regulation of protein transport GO:0051224 46 0.011
muscle contraction GO:0006936 101 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
cholesterol metabolic process GO:0008203 56 0.011
regulation of beta amyloid clearance GO:1900221 1 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
regulation of proteolysis GO:0030162 164 0.011
t cell activation GO:0042110 289 0.011
c21 steroid hormone biosynthetic process GO:0006700 3 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
regulation of androgen receptor signaling pathway GO:0060765 3 0.011
response to organic cyclic compound GO:0014070 198 0.011
meiotic cell cycle GO:0051321 122 0.011
nucleoside catabolic process GO:0009164 206 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
water soluble vitamin biosynthetic process GO:0042364 3 0.011
posttranscriptional gene silencing by rna GO:0035194 10 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
peptidyl amino acid modification GO:0018193 336 0.010
trivalent inorganic cation transport GO:0072512 5 0.010
microglia differentiation GO:0014004 2 0.010
nitrogen compound transport GO:0071705 271 0.010
cellular sodium ion homeostasis GO:0006883 1 0.010
ras protein signal transduction GO:0007265 77 0.010
endodermal cell fate specification GO:0001714 4 0.010
single organism nuclear import GO:1902593 95 0.010
protein ubiquitination GO:0016567 171 0.010
localization within membrane GO:0051668 4 0.010
detection of abiotic stimulus GO:0009582 60 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
cellular modified amino acid biosynthetic process GO:0042398 12 0.010
central nervous system morphogenesis GO:0021551 2 0.010
carbohydrate catabolic process GO:0016052 32 0.010
negative regulation of growth GO:0045926 99 0.010
detection of stimulus GO:0051606 84 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
spermatogenesis GO:0007283 284 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
lipid transport GO:0006869 98 0.010
negative regulation of cellular component organization GO:0051129 194 0.010

Atp6ap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.480
lipid storage disease DOID:9455 0 0.480
lysosomal storage disease DOID:3211 0 0.480
inherited metabolic disorder DOID:655 0 0.480
sphingolipidosis DOID:1927 0 0.222
central nervous system disease DOID:331 0 0.103
disease of anatomical entity DOID:7 0 0.103
nervous system disease DOID:863 0 0.103
brain disease DOID:936 0 0.086
immune system disease DOID:2914 0 0.045
cerebral degeneration DOID:1443 0 0.029
acquired metabolic disease DOID:0060158 0 0.028
non syndromic intellectual disability DOID:0050889 0 0.020
disease of mental health DOID:150 0 0.020
developmental disorder of mental health DOID:0060037 0 0.020
specific developmental disorder DOID:0060038 0 0.020
intellectual disability DOID:1059 0 0.020
retinal disease DOID:5679 0 0.020
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
musculoskeletal system disease DOID:17 0 0.017
neurodegenerative disease DOID:1289 0 0.015
connective tissue disease DOID:65 0 0.015
lymphatic system disease DOID:75 0 0.012
bone disease DOID:0080001 0 0.011
retinal degeneration DOID:8466 0 0.011
hematopoietic system disease DOID:74 0 0.010