Mus musculus

198 known processes

Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

(Aliases: Xnp,MRXS3,Hp1bp2,XH2,RAD54L,4833408C14Rik,DXHXS6677E,Rad54,AI447451,ATR2,Hp1bp38,HP1-BP38,ZNF-HX)

Atrx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 71 0.985
regulation of dna endoreduplication GO:0032875 3 0.954
protein methylation GO:0006479 81 0.940
negative regulation of dna dependent dna replication GO:2000104 1 0.908
genetic imprinting GO:0071514 27 0.885
mitotic sister chromatid cohesion GO:0007064 1 0.862
regulation of gene expression by genetic imprinting GO:0006349 15 0.842
chromatin modification GO:0016568 187 0.827
Human
chromatin organization GO:0006325 206 0.826
Human Fly
macromolecule methylation GO:0043414 120 0.774
cellular response to dna damage stimulus GO:0006974 207 0.720
covalent chromatin modification GO:0016569 163 0.622
methylation GO:0032259 134 0.592
ribonucleoside triphosphate metabolic process GO:0009199 220 0.579
Human Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.556
glycosyl compound metabolic process GO:1901657 246 0.491
Human Fly
histone lysine methylation GO:0034968 50 0.480
cellular amine metabolic process GO:0044106 44 0.443
synapsis GO:0007129 34 0.416
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.387
purine nucleoside triphosphate metabolic process GO:0009144 226 0.371
Human Fly
regulation of chromatin modification GO:1903308 57 0.371
meiotic cell cycle GO:0051321 122 0.367
protein localization to organelle GO:0033365 185 0.367
purine nucleoside metabolic process GO:0042278 241 0.367
Human Fly
cellular ketone metabolic process GO:0042180 84 0.367
response to radiation GO:0009314 165 0.354
stem cell differentiation GO:0048863 268 0.345
negative regulation of dna replication GO:0008156 4 0.342
regulation of histone methylation GO:0031060 30 0.341
ribonucleotide metabolic process GO:0009259 291 0.338
Human Fly
response to uv GO:0009411 44 0.337
double strand break repair GO:0006302 48 0.337
chromosome segregation GO:0007059 48 0.328
regulation of cellular amine metabolic process GO:0033238 20 0.319
atp metabolic process GO:0046034 75 0.316
Human Fly
regulation of cell cycle GO:0051726 281 0.292
protein alkylation GO:0008213 81 0.290
ribonucleoside monophosphate metabolic process GO:0009161 80 0.288
Human Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.284
peptidyl amino acid modification GO:0018193 336 0.282
histone modification GO:0016570 159 0.281
stem cell maintenance GO:0019827 130 0.275
cellular amino acid metabolic process GO:0006520 103 0.267
regulation of cellular component biogenesis GO:0044087 181 0.266
development of primary sexual characteristics GO:0045137 143 0.258
sister chromatid cohesion GO:0007062 12 0.258
glutamine family amino acid metabolic process GO:0009064 15 0.252
mitotic cell cycle GO:0000278 195 0.246
dna repair GO:0006281 107 0.242
positive regulation of cellular component biogenesis GO:0044089 94 0.241
meiotic nuclear division GO:0007126 115 0.235
dna endoreduplication GO:0042023 4 0.224
glycerophospholipid metabolic process GO:0006650 71 0.224
response to light stimulus GO:0009416 135 0.209
negative regulation of protein metabolic process GO:0051248 282 0.209
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.205
Human Fly
meiosis ii GO:0007135 7 0.202
meiotic sister chromatid cohesion GO:0051177 6 0.198
aromatic compound catabolic process GO:0019439 286 0.198
Human Fly
cell type specific apoptotic process GO:0097285 268 0.193
heterocycle catabolic process GO:0046700 280 0.191
Human Fly
negative regulation of cell cycle GO:0045786 123 0.190
learning or memory GO:0007611 148 0.184
nucleoside triphosphate metabolic process GO:0009141 230 0.183
Human Fly
nucleotide metabolic process GO:0009117 332 0.181
Human Fly
purine ribonucleotide metabolic process GO:0009150 290 0.177
Human Fly
ribonucleotide catabolic process GO:0009261 208 0.169
Human Fly
regulation of cell cycle phase transition GO:1901987 77 0.166
endocytosis GO:0006897 168 0.163
protein acylation GO:0043543 64 0.161
histone h3 k9 trimethylation GO:0036124 6 0.158
chromatin silencing GO:0006342 15 0.158
Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.156
axonogenesis GO:0007409 274 0.153
Fly
positive regulation of organelle organization GO:0010638 128 0.152
purine nucleoside monophosphate metabolic process GO:0009126 81 0.149
Human Fly
meiotic sister chromatid segregation GO:0045144 6 0.146
organelle fission GO:0048285 170 0.144
synaptonemal complex assembly GO:0007130 13 0.144
purine containing compound catabolic process GO:0072523 213 0.142
Human Fly
regulation of neuron projection development GO:0010975 169 0.141
chromosome organization involved in meiosis GO:0070192 39 0.139
organonitrogen compound catabolic process GO:1901565 264 0.134
Human Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.132
meiotic cell cycle process GO:1903046 77 0.132
negative regulation of protein modification process GO:0031400 163 0.131
ribose phosphate metabolic process GO:0019693 291 0.122
Human Fly
purine containing compound metabolic process GO:0072521 311 0.121
Human Fly
long term memory GO:0007616 15 0.120
amine metabolic process GO:0009308 45 0.117
nucleoside metabolic process GO:0009116 246 0.115
Human Fly
regulation of organelle organization GO:0033043 289 0.115
ribonucleoside metabolic process GO:0009119 245 0.115
Human Fly
peptidyl lysine modification GO:0018205 77 0.112
ribonucleoside catabolic process GO:0042454 206 0.110
Human Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.107
nucleoside catabolic process GO:0009164 206 0.107
Human Fly
nucleoside monophosphate metabolic process GO:0009123 85 0.107
Human Fly
negative regulation of cellular component organization GO:0051129 194 0.106
nuclear division GO:0000280 158 0.105
histone h3 k4 methylation GO:0051568 23 0.105
organophosphate catabolic process GO:0046434 232 0.104
Human Fly
regulation of histone modification GO:0031056 56 0.104
stem cell development GO:0048864 219 0.103
dendrite development GO:0016358 115 0.103
histone h3 k4 trimethylation GO:0080182 5 0.103
regulation of mitotic cell cycle GO:0007346 126 0.100
nucleoside phosphate metabolic process GO:0006753 338 0.098
Human Fly
ventricular system development GO:0021591 27 0.097
negative regulation of gene expression epigenetic GO:0045814 15 0.097
Fly
positive regulation of apoptotic process GO:0043065 217 0.097
regulation of system process GO:0044057 200 0.095
purine nucleotide metabolic process GO:0006163 302 0.095
Human Fly
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.095
cognition GO:0050890 149 0.094
histone h4 k20 methylation GO:0034770 8 0.093
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.093
proprioception GO:0019230 4 0.091
developmental maturation GO:0021700 193 0.090
organic cyclic compound catabolic process GO:1901361 295 0.089
Human Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.087
response to x ray GO:0010165 11 0.087
social behavior GO:0035176 21 0.087
dna dependent dna replication GO:0006261 24 0.087
internal protein amino acid acetylation GO:0006475 42 0.086
purine ribonucleoside metabolic process GO:0046128 241 0.084
Human Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.083
synapse organization GO:0050808 125 0.082
cell maturation GO:0048469 127 0.082
neuron maturation GO:0042551 29 0.079
male gamete generation GO:0048232 285 0.078
positive regulation of protein modification process GO:0031401 299 0.078
regulation of membrane potential GO:0042391 192 0.077
blood circulation GO:0008015 195 0.077
negative regulation of cell cycle phase transition GO:1901988 48 0.074
regulation of cell cycle process GO:0010564 160 0.074
cerebellum development GO:0021549 77 0.074
regulation of peptidyl serine phosphorylation GO:0033135 39 0.074
regulation of hydrolase activity GO:0051336 246 0.072
protein ubiquitination GO:0016567 171 0.072
cell cycle checkpoint GO:0000075 47 0.072
histone h3 k9 methylation GO:0051567 17 0.069
negative regulation of chromosome organization GO:2001251 30 0.067
negative regulation of phosphorylation GO:0042326 166 0.067
histone acetylation GO:0016573 41 0.066
purine nucleoside triphosphate catabolic process GO:0009146 203 0.066
Human Fly
memory GO:0007613 58 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.065
Human Fly
hindbrain development GO:0030902 128 0.065
carbohydrate derivative catabolic process GO:1901136 231 0.065
Human Fly
glycosyl compound catabolic process GO:1901658 206 0.064
Human Fly
regulation of chromosome organization GO:0033044 83 0.064
regulation of cell projection organization GO:0031344 206 0.063
negative regulation of cell proliferation GO:0008285 296 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.062
Human Fly
positive regulation of nervous system development GO:0051962 221 0.060
organic hydroxy compound metabolic process GO:1901615 203 0.060
positive regulation of programmed cell death GO:0043068 218 0.059
microtubule cytoskeleton organization GO:0000226 157 0.057
learning GO:0007612 98 0.056
nuclear import GO:0051170 95 0.056
regulation of neuron apoptotic process GO:0043523 122 0.056
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.056
myeloid cell differentiation GO:0030099 233 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
Human Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.055
regulation of neuron death GO:1901214 134 0.055
cellular response to organonitrogen compound GO:0071417 145 0.054
negative regulation of intracellular signal transduction GO:1902532 167 0.054
regulation of cellular response to stress GO:0080135 159 0.054
Fly
cellularization GO:0007349 1 0.054
response to organonitrogen compound GO:0010243 246 0.053
reciprocal dna recombination GO:0035825 16 0.053
purine ribonucleotide catabolic process GO:0009154 208 0.053
Human Fly
positive regulation of chromatin modification GO:1903310 28 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.051
positive regulation of apoptotic signaling pathway GO:2001235 95 0.051
sensory perception GO:0007600 245 0.050
mitotic cell cycle process GO:1903047 159 0.049
mitotic nuclear division GO:0007067 48 0.049
gene silencing GO:0016458 38 0.049
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.048
regulation of cytoplasmic transport GO:1903649 112 0.048
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.047
purine ribonucleoside catabolic process GO:0046130 205 0.046
Human Fly
peptidyl serine phosphorylation GO:0018105 74 0.046
regulation of intracellular transport GO:0032386 159 0.046
defecation GO:0030421 1 0.046
regulation of meiotic cell cycle GO:0051445 34 0.046
regionalization GO:0003002 337 0.046
negative regulation of histone methylation GO:0031061 10 0.046
bone development GO:0060348 120 0.046
glycerolipid metabolic process GO:0046486 122 0.045
leukocyte differentiation GO:0002521 342 0.045
cellular biogenic amine metabolic process GO:0006576 28 0.045
nucleotide catabolic process GO:0009166 217 0.045
Human Fly
establishment of protein localization to organelle GO:0072594 118 0.044
ras protein signal transduction GO:0007265 77 0.044
nucleoside triphosphate catabolic process GO:0009143 205 0.044
Human Fly
negative regulation of neuron death GO:1901215 98 0.043
regulation of protein targeting GO:1903533 61 0.043
nuclear transport GO:0051169 139 0.043
regulation of dna replication GO:0006275 17 0.043
regulation of synapse assembly GO:0051963 29 0.043
circulatory system process GO:0003013 197 0.043
axon guidance GO:0007411 141 0.043
Fly
cytoplasmic transport GO:0016482 234 0.042
reciprocal meiotic recombination GO:0007131 16 0.042
negative regulation of neuron apoptotic process GO:0043524 92 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.041
dna replication GO:0006260 52 0.041
mitotic sister chromatid segregation GO:0000070 14 0.040
negative regulation of cell cycle process GO:0010948 69 0.040
regulation of mitotic cell cycle phase transition GO:1901990 73 0.040
formation of primary germ layer GO:0001704 77 0.040
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.040
palate development GO:0060021 76 0.040
meiosis i GO:0007127 60 0.039
synaptonemal complex organization GO:0070193 15 0.038
regulation of chromatin organization GO:1902275 57 0.038
positive regulation of protein complex assembly GO:0031334 45 0.037
positive regulation of stress activated mapk cascade GO:0032874 48 0.037
protein targeting GO:0006605 143 0.037
cellular response to organic cyclic compound GO:0071407 87 0.037
neural tube development GO:0021915 160 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.036
Human Fly
gonad development GO:0008406 141 0.036
meiotic chromosome segregation GO:0045132 19 0.036
cellular lipid metabolic process GO:0044255 323 0.035
regulation of mrna export from nucleus GO:0010793 3 0.035
response to peptide hormone GO:0043434 127 0.035
genitalia development GO:0048806 37 0.035
Worm
response to growth factor GO:0070848 198 0.035
insulin receptor signaling pathway GO:0008286 49 0.035
double strand break repair via homologous recombination GO:0000724 21 0.035
forebrain development GO:0030900 302 0.035
synaptic transmission GO:0007268 329 0.034
protein polymerization GO:0051258 57 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.034
locomotory behavior GO:0007626 195 0.034
purine nucleoside monophosphate catabolic process GO:0009128 58 0.034
Human Fly
peptidyl lysine methylation GO:0018022 29 0.034
positive regulation of innate immune response GO:0045089 80 0.034
camera type eye development GO:0043010 266 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
endodermal cell fate specification GO:0001714 4 0.033
cellular carbohydrate metabolic process GO:0044262 119 0.033
actin filament organization GO:0007015 113 0.033
lipid localization GO:0010876 126 0.032
positive regulation of synapse assembly GO:0051965 18 0.032
mapk cascade GO:0000165 281 0.032
Fly
nitrogen compound transport GO:0071705 271 0.032
atp catabolic process GO:0006200 55 0.031
Human Fly
dna metabolic process GO:0006259 303 0.031
rna interference GO:0016246 2 0.031
negative regulation of molecular function GO:0044092 258 0.031
regulation of secretion GO:0051046 274 0.030
positive regulation of histone methylation GO:0031062 16 0.030
protein localization to nucleus GO:0034504 121 0.030
regulation of neuron differentiation GO:0045664 281 0.030
metencephalon development GO:0022037 89 0.029
chemotaxis GO:0006935 247 0.029
Fly
carbohydrate metabolic process GO:0005975 230 0.029
positive regulation of lymphocyte activation GO:0051251 140 0.029
dna templated transcription initiation GO:0006352 13 0.029
regulation of cell migration GO:0030334 219 0.029
male gonad development GO:0008584 88 0.029
maintenance of location GO:0051235 89 0.029
response to amino acid GO:0043200 37 0.029
positive regulation of cell death GO:0010942 224 0.028
positive regulation of chromosome organization GO:2001252 33 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
lateral inhibition GO:0046331 1 0.028
intracellular protein transport GO:0006886 204 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.027
Human Fly
cellular response to peptide GO:1901653 92 0.027
positive regulation of protein localization to nucleus GO:1900182 30 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
positive regulation of cell cycle GO:0045787 92 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
regulation of neurotransmitter levels GO:0001505 87 0.026
heterochromatin organization GO:0070828 4 0.026
Fly
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.026
regulation of protein complex assembly GO:0043254 83 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
Human Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.026
action potential GO:0001508 78 0.026
mitotic cell cycle checkpoint GO:0007093 31 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
skin development GO:0043588 220 0.026
sister chromatid segregation GO:0000819 20 0.025
lymphocyte differentiation GO:0030098 242 0.025
protein catabolic process GO:0030163 221 0.025
muscle contraction GO:0006936 101 0.025
regulation of systemic arterial blood pressure GO:0003073 61 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
Human Fly
intraspecies interaction between organisms GO:0051703 21 0.025
oxidation reduction process GO:0055114 342 0.025
regulation of hormone levels GO:0010817 211 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
positive regulation of cell activation GO:0050867 158 0.024
positive regulation of endocytosis GO:0045807 42 0.024
homeostasis of number of cells GO:0048872 210 0.024
regulation of respiratory gaseous exchange GO:0043576 18 0.024
blastocyst development GO:0001824 80 0.024
positive regulation of cell migration GO:0030335 109 0.024
innate immune response GO:0045087 157 0.024
regulation of cell motility GO:2000145 236 0.024
regulation of nuclear division GO:0051783 56 0.024
microtubule based process GO:0007017 236 0.024
striated muscle tissue development GO:0014706 293 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
gland development GO:0048732 330 0.023
retina development in camera type eye GO:0060041 119 0.023
negative regulation of histone modification GO:0031057 18 0.023
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.023
membrane organization GO:0061024 245 0.023
membrane depolarization GO:0051899 64 0.023
regulation of protein maturation GO:1903317 96 0.023
cardiolipin metabolic process GO:0032048 3 0.023
adult behavior GO:0030534 135 0.023
cell fate commitment GO:0045165 210 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.022
rna processing GO:0006396 105 0.022
internal peptidyl lysine acetylation GO:0018393 42 0.022
neuron apoptotic process GO:0051402 142 0.022
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.022
regulation of stem cell proliferation GO:0072091 78 0.022
dna conformation change GO:0071103 37 0.022
Human Fly
response to lipopolysaccharide GO:0032496 128 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
associative learning GO:0008306 61 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
protein import into nucleus GO:0006606 95 0.021
inflammatory response GO:0006954 244 0.021
phagocytosis GO:0006909 66 0.021
heterochromatin assembly GO:0031507 2 0.021
heart contraction GO:0060047 93 0.020
regulation of embryonic development GO:0045995 71 0.020
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.020
megakaryocyte differentiation GO:0030219 26 0.020
nucleoside monophosphate catabolic process GO:0009125 59 0.020
Human Fly
histone h4 k20 trimethylation GO:0034773 2 0.020
chromatin mediated maintenance of transcription GO:0048096 2 0.020
gastrulation GO:0007369 116 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
programmed necrotic cell death GO:0097300 28 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
negative regulation of lymphocyte activation GO:0051250 91 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
bmp signaling pathway GO:0030509 93 0.019
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.019
t cell differentiation GO:0030217 174 0.019
neuronal action potential GO:0019228 54 0.019
negative regulation of protein depolymerization GO:1901880 21 0.019
negative regulation of protein maturation GO:1903318 79 0.018
regulation of voltage gated calcium channel activity GO:1901385 4 0.018
response to peptide GO:1901652 136 0.018
protein maturation GO:0051604 176 0.018
peptidyl serine modification GO:0018209 83 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
alcohol metabolic process GO:0006066 116 0.018
somitogenesis GO:0001756 69 0.018
segmentation GO:0035282 93 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.018
male sex differentiation GO:0046661 109 0.018
cell fate specification GO:0001708 72 0.018
regulation of cell adhesion GO:0030155 154 0.018
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.018
regulation of dna templated transcription in response to stress GO:0043620 9 0.018
regulation of ras gtpase activity GO:0032318 88 0.018
gtp catabolic process GO:0006184 143 0.018
regulation of secretion by cell GO:1903530 249 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
protein import GO:0017038 101 0.017
ossification GO:0001503 216 0.017
gene silencing by rna GO:0031047 19 0.017
dna alkylation GO:0006305 43 0.017
regulation of thymocyte migration GO:2000410 2 0.017
steroid metabolic process GO:0008202 119 0.017
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.017
regulation of protein transport GO:0051223 163 0.017
negative regulation of mitotic cell cycle GO:0045930 58 0.017
mrna metabolic process GO:0016071 84 0.017
rna splicing GO:0008380 54 0.017
regulation of peptidyl lysine acetylation GO:2000756 22 0.017
negative regulation of organelle organization GO:0010639 90 0.017
multicellular organismal response to stress GO:0033555 62 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
muscle cell differentiation GO:0042692 261 0.016
rhythmic process GO:0048511 174 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
Human Fly
positive regulation of defense response GO:0031349 124 0.016
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
regulation of blood pressure GO:0008217 93 0.016
visual learning GO:0008542 44 0.016
endoderm formation GO:0001706 20 0.016
regulation of muscle tissue development GO:1901861 97 0.016
synapse assembly GO:0007416 56 0.016
cell division GO:0051301 120 0.016
mrna processing GO:0006397 63 0.016
respiratory system development GO:0060541 190 0.016
posttranscriptional gene silencing GO:0016441 10 0.016
positive regulation of stem cell proliferation GO:2000648 59 0.015
regulation of binding GO:0051098 111 0.015
negative regulation of b cell proliferation GO:0030889 13 0.015
protein deacylation GO:0035601 36 0.015
visual behavior GO:0007632 45 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
regulation of protein processing GO:0070613 96 0.015
oogenesis GO:0048477 56 0.015
stem cell proliferation GO:0072089 117 0.015
positive regulation of mapk cascade GO:0043410 170 0.014
alpha beta t cell activation GO:0046631 91 0.014
protein autophosphorylation GO:0046777 61 0.014
striated muscle contraction GO:0006941 45 0.014
regulation of rna export from nucleus GO:0046831 4 0.014
regulation of rho protein signal transduction GO:0035023 71 0.014
regulation of cell activation GO:0050865 289 0.014
response to acid chemical GO:0001101 111 0.014
response to decreased oxygen levels GO:0036293 59 0.014
negative regulation of protein processing GO:0010955 79 0.014
neuron death GO:0070997 154 0.014
protein deacetylation GO:0006476 32 0.014
calcium ion transport GO:0006816 159 0.014
response to testosterone GO:0033574 3 0.014
transforming growth factor beta1 production GO:0032905 3 0.014
negative regulation of microtubule depolymerization GO:0007026 13 0.014
hepaticobiliary system development GO:0061008 67 0.014
glutamine metabolic process GO:0006541 8 0.014
necrotic cell death GO:0070265 30 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
negative regulation of synapse assembly GO:0051964 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
peptidyl threonine phosphorylation GO:0018107 31 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
cellular response to external stimulus GO:0071496 88 0.013
positive regulation of intracellular protein transport GO:0090316 42 0.013
skeletal system development GO:0001501 356 0.013
negative regulation of defense response GO:0031348 77 0.013
protein processing GO:0016485 163 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
spermatogenesis GO:0007283 284 0.013
axon target recognition GO:0007412 4 0.013
sensory organ morphogenesis GO:0090596 242 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
Human Fly
negative regulation of odontogenesis GO:0042483 3 0.013
cell cycle switching GO:0060184 1 0.013
epithelial to mesenchymal transition GO:0001837 47 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
protein homotrimerization GO:0070207 4 0.013
erk1 and erk2 cascade GO:0070371 77 0.013
female gamete generation GO:0007292 74 0.013
insulin secretion GO:0030073 89 0.013
fear response GO:0042596 33 0.013
positive regulation of cell development GO:0010720 237 0.013
regulation of innate immune response GO:0045088 91 0.013
multicellular organism growth GO:0035264 161 0.012
feeding behavior GO:0007631 62 0.012
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.012
cellular magnesium ion homeostasis GO:0010961 3 0.012
cardiac muscle tissue development GO:0048738 130 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
response to organic cyclic compound GO:0014070 198 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
apoptotic signaling pathway GO:0097190 306 0.012
Fly
negative regulation of neuron differentiation GO:0045665 101 0.012
leukocyte proliferation GO:0070661 172 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
positive regulation of cardiac muscle hypertrophy GO:0010613 2 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
histone h3 k36 methylation GO:0010452 6 0.012

Atrx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cornelia de lange syndrome DOID:11725 0 0.077
pervasive developmental disorder DOID:0060040 0 0.042
autism spectrum disorder DOID:0060041 0 0.042
disease of mental health DOID:150 0 0.042
developmental disorder of mental health DOID:0060037 0 0.042
autistic disorder DOID:12849 0 0.029
x linked disease DOID:0050735 0 0.022
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013