|
|
pigment accumulation
|
GO:0043476 |
1 |
1.000
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
1.000
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.999
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
10 |
0.999
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.997
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.997
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.996
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.995
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.994
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.994
|
|
|
|
negative regulation of cell growth involved in cardiac muscle cell development
|
GO:0061052 |
2 |
0.994
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.992
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.992
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.991
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.991
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.990
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.989
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.989
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.988
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.987
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.987
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.984
|
|
|
|
cell proliferation involved in heart valve morphogenesis
|
GO:0003249 |
1 |
0.983
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.983
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.982
|
|
|
|
nephrogenic mesenchyme morphogenesis
|
GO:0072134 |
2 |
0.979
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.978
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.977
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.975
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.975
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.973
|
|
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.973
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.973
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.972
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.971
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
6 |
0.969
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.969
|
|
|
|
osteoblast development
|
GO:0002076 |
17 |
0.967
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.966
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.964
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.961
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.961
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.961
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.960
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.957
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.956
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.954
|
|
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.953
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.953
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.952
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.951
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.947
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.946
|
|
|
|
kidney mesenchyme morphogenesis
|
GO:0072131 |
4 |
0.945
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.945
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.944
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.943
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.941
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.941
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.939
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.939
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.939
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.938
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.933
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.932
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.932
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.931
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.930
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.928
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.927
|
|
|
|
endothelial cell activation
|
GO:0042118 |
1 |
0.926
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.925
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.925
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.921
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.920
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.915
|
|
|
|
hypermethylation of cpg island
|
GO:0044027 |
3 |
0.914
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.912
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.910
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.907
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.906
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.905
|
|
|
|
regulation of cell growth involved in cardiac muscle cell development
|
GO:0061050 |
3 |
0.902
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
3 |
0.901
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.897
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
2 |
0.897
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.893
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.892
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.891
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.889
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.887
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.883
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.881
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.878
|
|
|
|
epithelial to mesenchymal transition involved in endocardial cushion formation
|
GO:0003198 |
10 |
0.878
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.876
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.875
|
|
|
|
regulation of planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:2000163 |
1 |
0.874
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.871
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.871
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.868
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
11 |
0.868
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.867
|
Mouse |
|
|
regulation of peptidyl threonine phosphorylation
|
GO:0010799 |
12 |
0.865
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.864
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.862
|
|
|
|
negative regulation of nfat protein import into nucleus
|
GO:0051534 |
3 |
0.857
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.855
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.852
|
|
|
|
nephrogenic mesenchyme development
|
GO:0072076 |
3 |
0.851
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.850
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.848
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.846
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.844
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.841
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.840
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.839
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.839
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.839
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.836
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.835
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.831
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.831
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.829
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.828
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.827
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.827
|
|
|
|
negative regulation of cholesterol transport
|
GO:0032375 |
4 |
0.826
|
|
|
|
regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003250 |
1 |
0.826
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.823
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.822
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
1 |
0.819
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.819
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
7 |
0.818
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.818
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.817
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.808
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.808
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.808
|
|
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.808
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.805
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.800
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
13 |
0.798
|
|
|
|
regulation of calcineurin nfat signaling cascade
|
GO:0070884 |
5 |
0.795
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.794
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.793
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.790
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.790
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.790
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
4 |
0.789
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
8 |
0.789
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
12 |
0.781
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.780
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.776
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.772
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.768
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.767
|
|
|
|
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:2000148 |
1 |
0.764
|
|
|
|
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000166 |
1 |
0.764
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.759
|
|
|
|
negative regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000587 |
2 |
0.755
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.754
|
Zebrafish Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.754
|
Worm |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.752
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.750
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.749
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.748
|
|
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.747
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.746
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.739
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.738
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.736
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.734
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.732
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.730
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.730
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.725
|
|
|
|
regulation of phospholipase a2 activity
|
GO:0032429 |
3 |
0.721
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.718
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.717
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.706
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.706
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.703
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.702
|
|
|
|
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:2000162 |
1 |
0.698
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.697
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.693
|
|
|
|
negative regulation of planar cell polarity pathway involved in heart morphogenesis
|
GO:2000160 |
1 |
0.693
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.692
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.689
|
Fly |
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.689
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.684
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.683
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.679
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.674
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.670
|
|
|
|
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:2000149 |
1 |
0.670
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.668
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.662
|
Worm |
|
|
nuclear import
|
GO:0051170 |
95 |
0.662
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.660
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.657
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.655
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.654
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.654
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.653
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.652
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.652
|
|
|
|
social behavior
|
GO:0035176 |
21 |
0.649
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.649
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.648
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.646
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.645
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.641
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.634
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.631
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.629
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.629
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.627
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.626
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.625
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
13 |
0.624
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.622
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.622
|
|
|
|
brainstem development
|
GO:0003360 |
3 |
0.618
|
|
|
|
physiological muscle hypertrophy
|
GO:0003298 |
3 |
0.617
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.616
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.616
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.609
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.608
|
Worm |
|
|
habituation
|
GO:0046959 |
3 |
0.606
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.605
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.602
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.598
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.596
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.593
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.586
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.585
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.578
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.577
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.576
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.576
|
|
|
|
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
|
GO:0061324 |
2 |
0.574
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.574
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.571
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.569
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.564
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.554
|
Worm |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.554
|
|
|
|
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport
|
GO:0090118 |
1 |
0.554
|
|
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
10 |
0.549
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.544
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.541
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.539
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.538
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.538
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.537
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.536
|
Fly |
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.535
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.533
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.533
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.533
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
2 |
0.531
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.528
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.527
|
|
|
|
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:2000164 |
1 |
0.526
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.526
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.524
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.524
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.522
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.520
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.518
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.515
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.514
|
|
|
|
protein localization to microtubule cytoskeleton
|
GO:0072698 |
8 |
0.514
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.513
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.509
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.506
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.505
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.500
|
|
|
|
calcineurin nfat signaling cascade
|
GO:0033173 |
8 |
0.496
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.493
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.492
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.492
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.489
|
|
|
|
wnt signaling pathway involved in somitogenesis
|
GO:0090244 |
4 |
0.486
|
Zebrafish |
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.483
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
14 |
0.483
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.482
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.482
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.481
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
4 |
0.479
|
|
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.479
|
|
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.478
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.477
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.475
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.475
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.472
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.471
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.469
|
Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.468
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
10 |
0.467
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.465
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.462
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.462
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.458
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.457
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.455
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.455
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.454
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.453
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.449
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.443
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.441
|
Worm |
|
|
negative regulation of planar cell polarity pathway involved in neural tube closure
|
GO:2000168 |
1 |
0.440
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.439
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.436
|
|
|
|
regulation of planar cell polarity pathway involved in heart morphogenesis
|
GO:2000159 |
1 |
0.435
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.435
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.431
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.430
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
10 |
0.427
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.425
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.423
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.420
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.419
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.419
|
Zebrafish |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.418
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.418
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.414
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.414
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.414
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.412
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.409
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.409
|
Mouse |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.408
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.408
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.406
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.403
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.402
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.400
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.399
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.399
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.398
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.397
|
|
|
|
negative regulation of sterol transport
|
GO:0032372 |
4 |
0.396
|
|
|
|
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:2000161 |
1 |
0.394
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.394
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.393
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.393
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.392
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.390
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.385
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.385
|
Mouse |
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.385
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.383
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.379
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.378
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.375
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.375
|
|
|
|
protein localization to microtubule
|
GO:0035372 |
3 |
0.375
|
|
|
|
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:2000151 |
1 |
0.374
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.374
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.374
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.373
|
Mouse |
|
|
regulation of planar cell polarity pathway involved in neural tube closure
|
GO:2000167 |
1 |
0.373
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.372
|
|
|
|
regulation of presynaptic membrane organization
|
GO:1901629 |
3 |
0.368
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.367
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.367
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.366
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.366
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.361
|
Zebrafish Mouse |
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.361
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.361
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.359
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.355
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.354
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.354
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.354
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.353
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.351
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
18 |
0.351
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.351
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.350
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
56 |
0.349
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.348
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.346
|
|
|
|
regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000586 |
2 |
0.341
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.341
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.340
|
|
|
|
presynaptic membrane assembly
|
GO:0097105 |
7 |
0.336
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.334
|
|
|
|
planar cell polarity pathway involved in pericardium morphogenesis
|
GO:0061354 |
2 |
0.333
|
|
|
|
non canonical wnt signaling pathway involved in heart development
|
GO:0061341 |
3 |
0.332
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.332
|
|
|
|
intracellular cholesterol transport
|
GO:0032367 |
3 |
0.332
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.330
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.328
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.327
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.327
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.326
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.325
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.324
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.323
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.323
|
|
|
|
dna hypermethylation
|
GO:0044026 |
3 |
0.322
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.318
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
10 |
0.317
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.315
|
|
|
|
planar cell polarity pathway involved in heart morphogenesis
|
GO:0061346 |
3 |
0.315
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.313
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.313
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.312
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.312
|
|
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
2 |
0.311
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.308
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.308
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.307
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.307
|
Worm |
|
|
neural tube closure
|
GO:0001843 |
90 |
0.305
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.300
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.300
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.298
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
29 |
0.297
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.296
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.296
|
|
|
|
endocardial cushion formation
|
GO:0003272 |
13 |
0.296
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.295
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
22 |
0.293
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.290
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.288
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.287
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
2 |
0.283
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.280
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.279
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.279
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.278
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.278
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
4 |
0.275
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.274
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.273
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.271
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.270
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.270
|
|
|
|
midbrain development
|
GO:0030901 |
35 |
0.269
|
|
|
|
regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000165 |
1 |
0.269
|
|
|
|
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:2000150 |
1 |
0.269
|
|
|
|
wnt signaling pathway involved in forebrain neuroblast division
|
GO:0021874 |
2 |
0.268
|
|
|
|
skeletal muscle acetylcholine gated channel clustering
|
GO:0071340 |
7 |
0.267
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.267
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.264
|
|
|
|
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development
|
GO:0061310 |
1 |
0.263
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.261
|
|
|
|
sebaceous gland development
|
GO:0048733 |
7 |
0.258
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.258
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.257
|
|
|
|
planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:0061349 |
2 |
0.256
|
|
|
|
canonical wnt signaling pathway involved in neural crest cell differentiation
|
GO:0044335 |
1 |
0.253
|
|
|
|
establishment of planar polarity of embryonic epithelium
|
GO:0042249 |
16 |
0.253
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.252
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.251
|
|
|
|
neural tube patterning
|
GO:0021532 |
43 |
0.250
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.247
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
7 |
0.246
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.246
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.246
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.244
|
Fly |
|
|
smad protein signal transduction
|
GO:0060395 |
21 |
0.243
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.242
|
Mouse |
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.241
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.239
|
|
|
|
cell proliferation involved in outflow tract morphogenesis
|
GO:0061325 |
4 |
0.239
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.237
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.237
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.237
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
10 |
0.235
|
Worm |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.232
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.231
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.230
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.230
|
|
|
|
negative regulation of cardiac chamber morphogenesis
|
GO:1901220 |
2 |
0.229
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.228
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.227
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.226
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.226
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.225
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.225
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.222
|
|
|
|
endocardium development
|
GO:0003157 |
10 |
0.222
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.221
|
|
|
|
planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:0061347 |
2 |
0.221
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.220
|
|
