Mus musculus

109 known processes

Axin2

axin2

(Aliases: Axil,Conductin,Axi1)

Axin2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell development GO:0048864 219 0.798
Human Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.736
Mouse
skeletal system development GO:0001501 356 0.732
bmp signaling pathway GO:0030509 93 0.731
regionalization GO:0003002 337 0.723
canonical wnt signaling pathway GO:0060070 130 0.693
Human Mouse Worm
mapk cascade GO:0000165 281 0.668
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.664
fat cell differentiation GO:0045444 160 0.633
Mouse
embryonic organ morphogenesis GO:0048562 276 0.606
Mouse
segmentation GO:0035282 93 0.600
cell fate commitment GO:0045165 210 0.586
Worm
digestive system development GO:0055123 200 0.575
Mouse
regulation of neuron differentiation GO:0045664 281 0.575
gland development GO:0048732 330 0.565
hindbrain development GO:0030902 128 0.557
t cell differentiation GO:0030217 174 0.546
neural tube closure GO:0001843 90 0.537
forebrain development GO:0030900 302 0.526
striated muscle tissue development GO:0014706 293 0.522
digestive tract morphogenesis GO:0048546 147 0.513
Mouse
stem cell maintenance GO:0019827 130 0.510
Fly
negative regulation of cell proliferation GO:0008285 296 0.499
regulation of neuron projection development GO:0010975 169 0.499
regulation of cellular response to growth factor stimulus GO:0090287 82 0.489
Mouse
muscle tissue development GO:0060537 308 0.489
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.488
Human
polarity specification of proximal distal axis GO:0010085 2 0.485
telencephalon development GO:0021537 186 0.477
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.466
Mouse
positive regulation of cell development GO:0010720 237 0.457
Human
neural precursor cell proliferation GO:0061351 121 0.451
negative regulation of bmp signaling pathway GO:0030514 35 0.446
regulation of cell migration GO:0030334 219 0.441
mesenchyme development GO:0060485 152 0.437
Human
microtubule based process GO:0007017 236 0.432
Mouse Worm
chemotaxis GO:0006935 247 0.429
Worm
regulation of canonical wnt signaling pathway GO:0060828 82 0.422
Human Mouse
epithelial tube morphogenesis GO:0060562 303 0.420
cell adhesion GO:0007155 329 0.408
positive regulation of protein phosphorylation GO:0001934 242 0.408
Human Mouse Rat
respiratory system development GO:0060541 190 0.404
morphogenesis of a branching structure GO:0001763 203 0.401
forebrain generation of neurons GO:0021872 63 0.401
t cell activation GO:0042110 289 0.398
wnt signaling pathway GO:0016055 188 0.396
response to growth factor GO:0070848 198 0.385
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.383
ear morphogenesis GO:0042471 118 0.383
morphogenesis of a branching epithelium GO:0061138 193 0.379
stem cell proliferation GO:0072089 117 0.373
cell fate specification GO:0001708 72 0.369
Worm
embryonic genitalia morphogenesis GO:0030538 4 0.364
mesenchymal cell development GO:0014031 93 0.354
Human
lymphocyte differentiation GO:0030098 242 0.350
neuron projection guidance GO:0097485 141 0.349
Worm
negative regulation of cell development GO:0010721 169 0.344
neural tube development GO:0021915 160 0.339
blood vessel morphogenesis GO:0048514 285 0.336
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.331
Mouse
secretory granule localization GO:0032252 3 0.330
cerebellum development GO:0021549 77 0.328
homeostasis of number of cells GO:0048872 210 0.325
Mouse
regulation of muscle tissue development GO:1901861 97 0.325
negative regulation of nervous system development GO:0051961 156 0.321
muscle cell differentiation GO:0042692 261 0.321
central nervous system neuron differentiation GO:0021953 162 0.320
somitogenesis GO:0001756 69 0.317
cellular response to growth factor stimulus GO:0071363 197 0.317
Mouse
determination of left right symmetry GO:0007368 80 0.316
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.316
b cell activation GO:0042113 161 0.315
male sex differentiation GO:0046661 109 0.315
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.312
positive regulation of cell adhesion GO:0045785 80 0.304
regulation of bmp signaling pathway GO:0030510 60 0.300
formation of radial glial scaffolds GO:0021943 4 0.296
epithelial cell proliferation GO:0050673 174 0.287
lung development GO:0030324 164 0.287
regulation of gliogenesis GO:0014013 50 0.284
regulation of wnt signaling pathway GO:0030111 123 0.282
nucleoside phosphate metabolic process GO:0006753 338 0.281
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.280
regulation of cell cycle GO:0051726 281 0.279
glial cell differentiation GO:0010001 131 0.279
angiogenesis GO:0001525 201 0.277
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.274
neural tube formation GO:0001841 108 0.272
positive regulation of neuron differentiation GO:0045666 141 0.271
regulation of mapk cascade GO:0043408 248 0.269
Mouse
limbic system development GO:0021761 72 0.262
sensory organ morphogenesis GO:0090596 242 0.261
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.259
Mouse
mesodermal cell migration GO:0008078 4 0.259
endodermal cell fate specification GO:0001714 4 0.257
somatic stem cell maintenance GO:0035019 47 0.257
Fly
leukocyte differentiation GO:0002521 342 0.256
appendage development GO:0048736 166 0.253
Fly
regulation of stem cell proliferation GO:0072091 78 0.247
limb development GO:0060173 166 0.243
ossification GO:0001503 216 0.241
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.241
skeletal system morphogenesis GO:0048705 203 0.241
response to transforming growth factor beta GO:0071559 88 0.240
Mouse
positive regulation of programmed cell death GO:0043068 218 0.239
metencephalon development GO:0022037 89 0.238
muscle cell development GO:0055001 133 0.237
axonogenesis GO:0007409 274 0.237
Worm
kidney morphogenesis GO:0060993 83 0.235
cellular macromolecule catabolic process GO:0044265 206 0.233
Mouse
spinal cord development GO:0021510 81 0.232
regulation of cellular ketone metabolic process GO:0010565 66 0.231
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.230
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.229
Mouse
mitotic cell cycle GO:0000278 195 0.228
Worm
liver development GO:0001889 66 0.228
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.227
morphogenesis of embryonic epithelium GO:0016331 159 0.224
trachea gland development GO:0061153 3 0.223
myotube differentiation GO:0014902 105 0.222
developmental growth involved in morphogenesis GO:0060560 138 0.222
positive regulation of cell death GO:0010942 224 0.222
Human
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.222
nephric duct formation GO:0072179 4 0.220
embryonic epithelial tube formation GO:0001838 130 0.219
axon guidance GO:0007411 141 0.218
Worm
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.217
defecation GO:0030421 1 0.213
cerebral cortex development GO:0021987 86 0.211
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.211
Human Mouse
response to fibroblast growth factor GO:0071774 47 0.208
ureteric bud development GO:0001657 94 0.207
oligodendrocyte development GO:0014003 20 0.206
inner ear morphogenesis GO:0042472 101 0.201
regulation of stem cell differentiation GO:2000736 50 0.201
Human
embryonic appendage morphogenesis GO:0035113 126 0.201
cell type specific apoptotic process GO:0097285 268 0.199
positive regulation of protein modification process GO:0031401 299 0.199
Human Mouse Rat
hormone secretion GO:0046879 128 0.199
regulation of epithelial cell proliferation GO:0050678 141 0.196
regulation of chemotaxis GO:0050920 53 0.196
digestive tract development GO:0048565 190 0.193
Mouse
epithelial tube formation GO:0072175 130 0.191
purine nucleotide catabolic process GO:0006195 211 0.189
appendage morphogenesis GO:0035107 149 0.189
Fly
organelle localization GO:0051640 179 0.189
protein targeting GO:0006605 143 0.188
Human Mouse
positive regulation of cartilage development GO:0061036 18 0.188
odontogenesis of dentin containing tooth GO:0042475 66 0.184
positive regulation of cell motility GO:2000147 116 0.184
neuroblast proliferation GO:0007405 49 0.184
regulation of cellular amino acid metabolic process GO:0006521 5 0.184
cardiac muscle tissue growth GO:0055017 37 0.183
modification dependent macromolecule catabolic process GO:0043632 133 0.182
Mouse
vagus nerve development GO:0021564 3 0.181
nucleoside triphosphate catabolic process GO:0009143 205 0.181
heterocycle catabolic process GO:0046700 280 0.180
regulation of cell motility GO:2000145 236 0.180
branching morphogenesis of an epithelial tube GO:0048754 159 0.179
epithelial to mesenchymal transition GO:0001837 47 0.179
Human
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.178
regulation of organ growth GO:0046620 61 0.177
sensory perception GO:0007600 245 0.177
Mouse
limb morphogenesis GO:0035108 149 0.177
palate development GO:0060021 76 0.177
protein modification by small protein conjugation GO:0032446 187 0.176
Mouse
organ growth GO:0035265 117 0.175
negative regulation of neuron differentiation GO:0045665 101 0.174
positive regulation of cell activation GO:0050867 158 0.174
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.173
cardiac muscle tissue development GO:0048738 130 0.173
positive regulation of cell migration GO:0030335 109 0.172
positive regulation of nervous system development GO:0051962 221 0.172
regulation of cardiac muscle tissue growth GO:0055021 26 0.171
purine ribonucleoside catabolic process GO:0046130 205 0.169
cardiocyte differentiation GO:0035051 87 0.169
purine ribonucleotide metabolic process GO:0009150 290 0.169
positive regulation of mapk cascade GO:0043410 170 0.169
Mouse
mesenchymal cell differentiation GO:0048762 107 0.168
Human
developmental cell growth GO:0048588 84 0.166
single organism cell adhesion GO:0098602 156 0.166
regulation of epithelial to mesenchymal transition GO:0010717 22 0.166
Human
respiratory tube development GO:0030323 167 0.164
pituitary gland development GO:0021983 38 0.162
somite development GO:0061053 81 0.162
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.161
lymphocyte proliferation GO:0046651 164 0.160
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.160
Mouse
mesenchyme morphogenesis GO:0072132 32 0.160
regulation of neuron death GO:1901214 134 0.159
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.158
Human
regulation of establishment of protein localization GO:0070201 181 0.157
Human Mouse
stem cell differentiation GO:0048863 268 0.157
Human Fly
apoptotic signaling pathway GO:0097190 306 0.156
protein localization to organelle GO:0033365 185 0.156
Human Mouse
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.155
positive regulation of cellular catabolic process GO:0031331 148 0.154
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.153
Human
nucleoside catabolic process GO:0009164 206 0.153
regulation of anatomical structure size GO:0090066 178 0.153
cardiac septum development GO:0003279 59 0.153
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.152
cellular response to hormone stimulus GO:0032870 150 0.151
regulation of organelle organization GO:0033043 289 0.151
cytoplasmic transport GO:0016482 234 0.151
Human Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.150
alpha beta t cell differentiation GO:0046632 69 0.149
mesoderm morphogenesis GO:0048332 64 0.149
Mouse
hippocampus development GO:0021766 52 0.149
camera type eye development GO:0043010 266 0.149
regulation of cellular catabolic process GO:0031329 242 0.148
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.147
purine containing compound metabolic process GO:0072521 311 0.146
positive regulation of rho gtpase activity GO:0032321 41 0.146
regulation of lymphocyte activation GO:0051249 240 0.144
forebrain neuron differentiation GO:0021879 52 0.144
intracellular protein transport GO:0006886 204 0.144
Human Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.143
ras protein signal transduction GO:0007265 77 0.142
primary neural tube formation GO:0014020 95 0.142
positive regulation of epithelial cell proliferation GO:0050679 68 0.142
regulation of heart growth GO:0060420 31 0.142
negative regulation of neuron projection development GO:0010977 50 0.141
cardiac septum morphogenesis GO:0060411 46 0.140
mesonephric tubule morphogenesis GO:0072171 63 0.140
nephron tubule morphogenesis GO:0072078 68 0.140
regulation of nucleocytoplasmic transport GO:0046822 73 0.139
Human Mouse
striated muscle cell development GO:0055002 125 0.139
cellular nitrogen compound catabolic process GO:0044270 280 0.139
peptide hormone secretion GO:0030072 109 0.138
hepaticobiliary system development GO:0061008 67 0.138
cardiac muscle cell proliferation GO:0060038 31 0.137
embryonic skeletal system development GO:0048706 120 0.137
Mouse
cardiac epithelial to mesenchymal transition GO:0060317 18 0.137
kidney development GO:0001822 213 0.137
germ cell development GO:0007281 185 0.136
Fly
regulation of cardiac muscle cell proliferation GO:0060043 23 0.136
skeletal muscle organ development GO:0060538 163 0.135
rho protein signal transduction GO:0007266 32 0.135
neuronal action potential GO:0019228 54 0.135
gliogenesis GO:0042063 141 0.134
leukocyte proliferation GO:0070661 172 0.133
nephron morphogenesis GO:0072028 69 0.132
pharynx development GO:0060465 1 0.132
lipid biosynthetic process GO:0008610 179 0.132
protein localization to nucleus GO:0034504 121 0.132
Human Mouse
wound healing GO:0042060 157 0.131
negative regulation of cellular component organization GO:0051129 194 0.131
negative regulation of growth GO:0045926 99 0.130
regulation of cardioblast differentiation GO:0051890 3 0.130
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.130
ribonucleoside catabolic process GO:0042454 206 0.129
positive regulation of cell cycle GO:0045787 92 0.129
single organismal cell cell adhesion GO:0016337 131 0.129
bone development GO:0060348 120 0.129
regulation of lymphocyte differentiation GO:0045619 107 0.129
negative regulation of synapse assembly GO:0051964 3 0.129
odontogenesis GO:0042476 78 0.128
Human
small gtpase mediated signal transduction GO:0007264 97 0.127
regulation of cell projection organization GO:0031344 206 0.127
regulation of intracellular transport GO:0032386 159 0.127
Human Mouse
pallium development GO:0021543 120 0.126
mesonephros development GO:0001823 97 0.126
regulation of cartilage development GO:0061035 44 0.126
ventricular septum development GO:0003281 42 0.125
cartilage development GO:0051216 140 0.125
regulation of leukocyte differentiation GO:1902105 159 0.125
regulation of cell activation GO:0050865 289 0.123
alpha beta t cell activation GO:0046631 91 0.123
outflow tract morphogenesis GO:0003151 53 0.122
mitotic cell cycle process GO:1903047 159 0.122
Worm
autonomic nervous system development GO:0048483 43 0.121
nucleobase containing small molecule metabolic process GO:0055086 352 0.121
cellular amino acid metabolic process GO:0006520 103 0.121
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.120
ureteric bud morphogenesis GO:0060675 62 0.120
purine nucleoside triphosphate catabolic process GO:0009146 203 0.119
ribonucleoside metabolic process GO:0009119 245 0.118
cardiac endothelial cell differentiation GO:0003348 4 0.118
cellular protein complex assembly GO:0043623 116 0.118
protein ubiquitination GO:0016567 171 0.118
Mouse
tube formation GO:0035148 140 0.117
regulation of cell adhesion GO:0030155 154 0.117
positive regulation of lymphocyte activation GO:0051251 140 0.117
amide transport GO:0042886 138 0.116
regulation of cellular amine metabolic process GO:0033238 20 0.115
myoblast differentiation GO:0045445 52 0.115
heart growth GO:0060419 45 0.115
gastrulation GO:0007369 116 0.115
Mouse
purine nucleotide metabolic process GO:0006163 302 0.114
membrane organization GO:0061024 245 0.114
neuron apoptotic process GO:0051402 142 0.114
ribonucleotide metabolic process GO:0009259 291 0.114
nucleoside metabolic process GO:0009116 246 0.114
immune effector process GO:0002252 321 0.113
protein modification by small protein conjugation or removal GO:0070647 207 0.113
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.113
endocrine system development GO:0035270 98 0.112
t cell activation involved in immune response GO:0002286 43 0.112
regulation of myeloid cell differentiation GO:0045637 96 0.112
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.111
regulation of fat cell differentiation GO:0045598 81 0.111
Mouse
spermatogenesis GO:0007283 284 0.110
multi multicellular organism process GO:0044706 109 0.110
Worm
trachea cartilage morphogenesis GO:0060535 4 0.110
regulation of ion transport GO:0043269 215 0.110
glial cell development GO:0021782 54 0.109
glycosyl compound metabolic process GO:1901657 246 0.109
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.109
regulation of cytoskeleton organization GO:0051493 122 0.107
nucleotide metabolic process GO:0009117 332 0.107
female sex differentiation GO:0046660 84 0.107
regulation of lymphocyte proliferation GO:0050670 117 0.107
development of primary sexual characteristics GO:0045137 143 0.106
Worm
regulation of cardiac muscle tissue development GO:0055024 31 0.106
negative regulation of axon extension GO:0030517 19 0.106
tube closure GO:0060606 91 0.106
positive regulation of apoptotic process GO:0043065 217 0.106
erythrocyte differentiation GO:0030218 88 0.106
cytokine production GO:0001816 319 0.105
cardiac right atrium morphogenesis GO:0003213 3 0.104
oligodendrocyte differentiation GO:0048709 53 0.103
muscle fiber development GO:0048747 76 0.103
renal system development GO:0072001 225 0.102
negative regulation of cell cycle GO:0045786 123 0.102
peptide transport GO:0015833 133 0.102
genitalia development GO:0048806 37 0.102
Worm
microtubule cytoskeleton organization GO:0000226 157 0.102
Mouse Worm
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.102
anatomical structure maturation GO:0071695 49 0.100
regulation of membrane potential GO:0042391 192 0.100
cardiac ventricle morphogenesis GO:0003208 50 0.100
axial mesoderm development GO:0048318 8 0.100
Mouse
nuclear transport GO:0051169 139 0.100
Human Mouse
cell cell signaling involved in cell fate commitment GO:0045168 35 0.099
regulation of peptide transport GO:0090087 91 0.099
genitalia morphogenesis GO:0035112 11 0.099
ribonucleoside triphosphate catabolic process GO:0009203 199 0.098
regulation of cell substrate adhesion GO:0010810 73 0.097
guanosine containing compound catabolic process GO:1901069 144 0.097
positive regulation of transferase activity GO:0051347 167 0.097
Mouse Rat
muscular septum morphogenesis GO:0003150 4 0.097
neuron migration GO:0001764 122 0.096
regulation of neuron apoptotic process GO:0043523 122 0.095
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.095
negative regulation of wnt signaling pathway GO:0030178 73 0.095
Human Mouse Rat Worm Fly
regulation of protein maturation GO:1903317 96 0.095
metanephric mesenchyme morphogenesis GO:0072133 4 0.095
ribonucleotide catabolic process GO:0009261 208 0.094
glycosyl compound catabolic process GO:1901658 206 0.094
regulation of axon guidance GO:1902667 13 0.094
smoothened signaling pathway GO:0007224 105 0.093
regulation of hormone secretion GO:0046883 88 0.093
regulation of ras gtpase activity GO:0032318 88 0.093
muscle cell proliferation GO:0033002 52 0.093
regulation of apoptotic signaling pathway GO:2001233 197 0.092
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.092
myeloid cell homeostasis GO:0002262 114 0.092
Mouse
placenta development GO:0001890 140 0.092
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.092
regulation of axon extension GO:0030516 43 0.092
neural crest cell differentiation GO:0014033 54 0.091
bone mineralization GO:0030282 54 0.091
maintenance of cell number GO:0098727 3 0.091
myeloid leukocyte differentiation GO:0002573 119 0.091
negative regulation of cell motility GO:2000146 61 0.090
cell differentiation in spinal cord GO:0021515 53 0.090
renal vesicle induction GO:0072034 3 0.090
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.089
myeloid cell differentiation GO:0030099 233 0.089
cell division GO:0051301 120 0.089
guanosine containing compound metabolic process GO:1901068 144 0.089
regulation of cytokine production GO:0001817 266 0.089
insulin secretion GO:0030073 89 0.088
muscle system process GO:0003012 141 0.088
covalent chromatin modification GO:0016569 163 0.088
cardiac chamber morphogenesis GO:0003206 93 0.088
regulation of protein targeting GO:1903533 61 0.087
Human Mouse
nucleotide catabolic process GO:0009166 217 0.087
protein maturation GO:0051604 176 0.087
cerebellar cortex morphogenesis GO:0021696 32 0.087
meiotic nuclear division GO:0007126 115 0.087
pancreas development GO:0031016 57 0.086
ameboidal type cell migration GO:0001667 128 0.086
protein import GO:0017038 101 0.086
Human Mouse
purine nucleoside catabolic process GO:0006152 205 0.085
cerebral cortex cell migration GO:0021795 44 0.085
regulation of osteoblast differentiation GO:0045667 67 0.084
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.084
Mouse
developmental maturation GO:0021700 193 0.084
regulation of organ formation GO:0003156 34 0.083
negative regulation of protein phosphorylation GO:0001933 126 0.083
purine ribonucleoside metabolic process GO:0046128 241 0.082
modification dependent protein catabolic process GO:0019941 133 0.082
Mouse
regulation of receptor binding GO:1900120 4 0.082
regulation of alpha beta t cell differentiation GO:0046637 35 0.082
regulation of secretion by cell GO:1903530 249 0.082
nucleocytoplasmic transport GO:0006913 139 0.082
Human Mouse
t cell differentiation in thymus GO:0033077 77 0.082
biomineral tissue development GO:0031214 64 0.081
purine ribonucleotide catabolic process GO:0009154 208 0.081
skin development GO:0043588 220 0.081
regulation of system process GO:0044057 200 0.081
mammary gland duct morphogenesis GO:0060603 38 0.081
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.081
positive regulation of t cell activation GO:0050870 101 0.081
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.081
negative regulation of apoptotic signaling pathway GO:2001234 104 0.080
embryonic heart tube morphogenesis GO:0003143 51 0.080
developmental induction GO:0031128 34 0.080
mesonephric epithelium development GO:0072163 94 0.080
cardiac muscle cell differentiation GO:0055007 69 0.080
development of primary male sexual characteristics GO:0046546 88 0.080
forebrain neuron fate commitment GO:0021877 13 0.079
cellular homeostasis GO:0019725 240 0.079
glandular epithelial cell differentiation GO:0002067 38 0.079
neuron projection extension GO:1990138 64 0.079
regulation of jnk cascade GO:0046328 62 0.078
Mouse
purine containing compound catabolic process GO:0072523 213 0.078
posttranscriptional gene silencing GO:0016441 10 0.078
leukocyte activation involved in immune response GO:0002366 126 0.078
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.078
regulation of glial cell differentiation GO:0045685 41 0.078
male gamete generation GO:0048232 285 0.078
regulation of neural precursor cell proliferation GO:2000177 70 0.078
cell substrate adhesion GO:0031589 130 0.078
hair follicle development GO:0001942 85 0.078
positive regulation of protein kinase activity GO:0045860 144 0.078
Mouse Rat
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.078
bone morphogenesis GO:0060349 78 0.077
purine nucleoside triphosphate metabolic process GO:0009144 226 0.077
blastocyst development GO:0001824 80 0.077
negative regulation of cell fate specification GO:0009996 4 0.077
negative regulation of osteoblast proliferation GO:0033689 4 0.077
positive regulation of gtpase activity GO:0043547 85 0.077
ribose phosphate metabolic process GO:0019693 291 0.076
regulation of organ morphogenesis GO:2000027 144 0.075
regulation of cell growth GO:0001558 91 0.075
positive regulation of growth GO:0045927 104 0.075
Worm
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.075
negative regulation of cell growth GO:0030308 44 0.075
mesonephric tubule development GO:0072164 94 0.075
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.074
methylation GO:0032259 134 0.074
protein catabolic process GO:0030163 221 0.074
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.073
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.073
Mouse
regulation of osteoblast proliferation GO:0033688 15 0.073
asymmetric neuroblast division GO:0055059 1 0.073
lung induction GO:0060492 3 0.073
cellular chemical homeostasis GO:0055082 215 0.072
forebrain cell migration GO:0021885 58 0.071
apoptotic process involved in morphogenesis GO:0060561 25 0.071
positive regulation of glial cell differentiation GO:0045687 21 0.071
regulation of vesicle mediated transport GO:0060627 139 0.071
positive regulation of neuron projection development GO:0010976 79 0.071
regulation of purine nucleotide metabolic process GO:1900542 169 0.071
regulation of hormone levels GO:0010817 211 0.071
cell migration in hindbrain GO:0021535 16 0.070
atrioventricular valve morphogenesis GO:0003181 13 0.070
single organism nuclear import GO:1902593 95 0.070
Human Mouse
negative regulation of cell migration GO:0030336 59 0.070
regulation of asymmetric cell division GO:0009786 4 0.069
embryonic digit morphogenesis GO:0042733 56 0.069
salivary gland development GO:0007431 37 0.069
regulation of hydrolase activity GO:0051336 246 0.069
syncytium formation by plasma membrane fusion GO:0000768 42 0.069
forebrain radial glial cell differentiation GO:0021861 4 0.069
organophosphate catabolic process GO:0046434 232 0.069
neuron death GO:0070997 154 0.069
hemostasis GO:0007599 78 0.068
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.068
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.068
peptidyl amino acid modification GO:0018193 336 0.068
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.068
cardiac muscle tissue morphogenesis GO:0055008 44 0.067
ubiquitin dependent protein catabolic process GO:0006511 129 0.067
Mouse
negative regulation of molecular function GO:0044092 258 0.067
epidermis development GO:0008544 187 0.067
male gonad development GO:0008584 88 0.067
branching involved in salivary gland morphogenesis GO:0060445 26 0.067
cellular protein catabolic process GO:0044257 155 0.067
Mouse
midbrain development GO:0030901 35 0.067
axon extension involved in axon guidance GO:0048846 14 0.066
regulation of myeloid leukocyte differentiation GO:0002761 58 0.066
embryonic skeletal system morphogenesis GO:0048704 91 0.066
Mouse
negative regulation of hormone biosynthetic process GO:0032353 4 0.066
formation of organ boundary GO:0010160 1 0.066
regulation of epidermis development GO:0045682 33 0.066
positive regulation of cell cycle process GO:0090068 61 0.066
regulation of intracellular protein transport GO:0033157 82 0.066
Human Mouse
b cell differentiation GO:0030183 78 0.066
alpha beta t cell activation involved in immune response GO:0002287 31 0.066
macromolecule catabolic process GO:0009057 281 0.065
Mouse
determination of heart left right asymmetry GO:0061371 48 0.065
regulation of binding GO:0051098 111 0.065

Axin2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.177
Human
cancer DOID:162 0 0.157
Human
organ system cancer DOID:0050686 0 0.079
Human