Mus musculus

503 known processes

Bax

BCL2-associated X protein

Bax biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 1.000
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 1.000
mitochondrial fusion GO:0008053 9 1.000
release of cytochrome c from mitochondria GO:0001836 23 1.000
cellular response to gamma radiation GO:0071480 4 1.000
Mouse
positive regulation of mitochondrion organization GO:0010822 17 1.000
Human Worm
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 1.000
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.999
cd8 positive alpha beta t cell lineage commitment GO:0043375 1 0.999
Mouse
regulation of mitochondrial membrane permeability GO:0046902 17 0.998
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.998
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.998
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.997
positive regulation of pigment cell differentiation GO:0050942 5 0.996
Mouse
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 3 0.994
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 3 0.993
Mouse
positive regulation of neuron maturation GO:0014042 2 0.993
Mouse
cochlear nucleus development GO:0021747 4 0.993
Mouse
positive regulation of melanocyte differentiation GO:0045636 5 0.991
Mouse
positive regulation of developmental pigmentation GO:0048087 6 0.990
response to uv b GO:0010224 5 0.990
Mouse
positive regulation of b cell apoptotic process GO:0002904 4 0.989
negative regulation of b cell apoptotic process GO:0002903 7 0.987
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.986
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.982
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.981
positive regulation of peptidase activity GO:0010952 49 0.980
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 4 0.979
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.978
positive regulation of neuroepithelial cell differentiation GO:1902913 5 0.977
Mouse
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.975
Mouse
post embryonic eye morphogenesis GO:0048050 4 0.972
regulation of melanocyte differentiation GO:0045634 7 0.968
Mouse
response to ischemia GO:0002931 14 0.960
Mouse
apoptotic process involved in mammary gland involution GO:0060057 4 0.955
response to endoplasmic reticulum stress GO:0034976 53 0.954
regulation of nitrogen utilization GO:0006808 2 0.954
sphingolipid metabolic process GO:0006665 45 0.948
regulation of membrane permeability GO:0090559 18 0.947
mitochondrial membrane organization GO:0007006 26 0.945
mitochondrial outer membrane permeabilization GO:0097345 10 0.943
t cell homeostatic proliferation GO:0001777 4 0.938
regulation of mitochondrion organization GO:0010821 27 0.934
Human Worm
hepatocyte apoptotic process GO:0097284 11 0.932
Mouse
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.920
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.916
positive regulation of cellular response to oxidative stress GO:1900409 6 0.913
Mouse
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.912
amine metabolic process GO:0009308 45 0.911
regulation of cell cycle GO:0051726 281 0.906
cytosolic calcium ion transport GO:0060401 48 0.904
organelle fusion GO:0048284 28 0.899
male gamete generation GO:0048232 285 0.898
cellular response to glucose starvation GO:0042149 5 0.897
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.895
membrane fusion GO:0061025 38 0.894
cellular response to radiation GO:0071478 28 0.894
b cell selection GO:0002339 3 0.893
positive regulation of cell maturation GO:1903431 4 0.885
Mouse
negative regulation of neuron death GO:1901215 98 0.881
positive regulation of skeletal muscle fiber development GO:0048743 3 0.880
Mouse
cytoplasmic transport GO:0016482 234 0.880
t cell homeostasis GO:0043029 35 0.879
extrinsic apoptotic signaling pathway GO:0097191 126 0.879
glycosyl compound catabolic process GO:1901658 206 0.879
Worm
cellular response to dna damage stimulus GO:0006974 207 0.875
regulation of cellular response to oxidative stress GO:1900407 19 0.866
Mouse
membrane organization GO:0061024 245 0.860
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.856
regulation of developmental pigmentation GO:0048070 14 0.852
ureteric bud morphogenesis GO:0060675 62 0.850
Mouse
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.850
negative regulation of homeostatic process GO:0032845 71 0.849
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.840
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death GO:1902445 2 0.840
regulation of cellular amine metabolic process GO:0033238 20 0.839
signal transduction in absence of ligand GO:0038034 55 0.838
negative regulation of osteoblast proliferation GO:0033689 4 0.836
Mouse
cellular amino acid metabolic process GO:0006520 103 0.836
guanosine containing compound metabolic process GO:1901068 144 0.831
Worm
regulation of mitotic cell cycle phase transition GO:1901990 73 0.829
Mouse
viral process GO:0016032 41 0.827
Mouse
g1 s transition of mitotic cell cycle GO:0000082 57 0.823
Mouse
protein maturation GO:0051604 176 0.821
pons development GO:0021548 13 0.816
Mouse
positive regulation of response to oxidative stress GO:1902884 6 0.813
Mouse
positive regulation of proteolysis GO:0045862 85 0.812
nephron tubule morphogenesis GO:0072078 68 0.811
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.809
Worm
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 10 0.809
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.804
reactive oxygen species metabolic process GO:0072593 84 0.804
Mouse
muscle cell differentiation GO:0042692 261 0.799
Mouse
regulation of peptidyl serine phosphorylation GO:0033135 39 0.788
response to mycotoxin GO:0010046 1 0.786
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.784
apoptotic signaling pathway GO:0097190 306 0.779
spermatogenesis GO:0007283 284 0.776
nucleotide catabolic process GO:0009166 217 0.775
Worm
aromatic compound catabolic process GO:0019439 286 0.768
Human Worm
regulation of gtp catabolic process GO:0033124 113 0.767
Worm
viral genome replication GO:0019079 17 0.766
Mouse
kidney epithelium development GO:0072073 121 0.764
Mouse
renal tubule development GO:0061326 87 0.762
Mouse
mitochondrial transport GO:0006839 36 0.761
leukocyte homeostasis GO:0001776 79 0.758
purine ribonucleoside catabolic process GO:0046130 205 0.757
Worm
camera type eye development GO:0043010 266 0.754
release of sequestered calcium ion into cytosol GO:0051209 42 0.752
regulation of membrane potential GO:0042391 192 0.751
Human Mouse
development of primary sexual characteristics GO:0045137 143 0.751
mammary gland epithelial cell proliferation GO:0033598 24 0.743
mesonephric tubule development GO:0072164 94 0.740
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.737
Worm
nephron tubule development GO:0072080 84 0.735
Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.734
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.734
positive regulation of oxidative stress induced neuron death GO:1903223 3 0.729
Mouse
organophosphate catabolic process GO:0046434 232 0.726
Worm
apoptotic mitochondrial changes GO:0008637 48 0.726
melanocyte differentiation GO:0030318 25 0.725
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.711
Worm
ribonucleoside metabolic process GO:0009119 245 0.710
Worm
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.709
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.708
Mouse
regulation of cell cycle phase transition GO:1901987 77 0.707
Mouse
regulation of response to oxidative stress GO:1902882 19 0.703
Mouse
ribonucleotide metabolic process GO:0009259 291 0.703
Worm
purine nucleotide catabolic process GO:0006195 211 0.697
Worm
positive regulation of myotube differentiation GO:0010831 24 0.695
Mouse
focal adhesion assembly GO:0048041 19 0.691
Mouse
regulation of proteolysis GO:0030162 164 0.691
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.690
Human
carbohydrate derivative catabolic process GO:1901136 231 0.689
Worm
positive regulation of protein oligomerization GO:0032461 4 0.688
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.685
Human Worm
positive regulation of cell death GO:0010942 224 0.685
actin cytoskeleton organization GO:0030036 220 0.682
Mouse
signal transduction by p53 class mediator GO:0072331 51 0.679
fertilization GO:0009566 127 0.678
cellular response to light stimulus GO:0071482 19 0.673
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.673
Mouse
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.668
positive regulation of neuron death GO:1901216 28 0.666
b cell differentiation GO:0030183 78 0.665
regulation of pigment cell differentiation GO:0050932 7 0.664
Mouse
response to ionizing radiation GO:0010212 42 0.663
regulation of b cell apoptotic process GO:0002902 13 0.663
purine nucleoside triphosphate catabolic process GO:0009146 203 0.663
Worm
urogenital system development GO:0001655 261 0.660
positive regulation of protein phosphorylation GO:0001934 242 0.658
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.656
nucleoside phosphate catabolic process GO:1901292 222 0.654
Worm
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.652
nitrogen utilization GO:0019740 2 0.644
programmed necrotic cell death GO:0097300 28 0.642
nucleoside triphosphate metabolic process GO:0009141 230 0.641
Worm
neuron death GO:0070997 154 0.641
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.633
Worm
positive regulation of gtpase activity GO:0043547 85 0.632
Worm
morphogenesis of a branching structure GO:0001763 203 0.623
regulation of intracellular transport GO:0032386 159 0.619
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.619
Mouse
positive regulation of organelle organization GO:0010638 128 0.618
Human Worm
retinal cell programmed cell death GO:0046666 8 0.617
developmental pigmentation GO:0048066 40 0.617
thymocyte apoptotic process GO:0070242 19 0.616
calcium ion transport into cytosol GO:0060402 48 0.616
protein processing GO:0016485 163 0.613
sertoli cell proliferation GO:0060011 5 0.611
mitochondrion organization GO:0007005 134 0.610
embryonic appendage morphogenesis GO:0035113 126 0.608
ectopic germ cell programmed cell death GO:0035234 9 0.607
regulation of retinal cell programmed cell death GO:0046668 5 0.598
Mouse
protein localization to organelle GO:0033365 185 0.596
regulation of cellular response to stress GO:0080135 159 0.595
Human Mouse
regulation of neuron death GO:1901214 134 0.589
establishment of protein localization to membrane GO:0090150 54 0.586
t cell differentiation in thymus GO:0033077 77 0.583
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.581
ovarian follicle development GO:0001541 40 0.580
calcium ion transport GO:0006816 159 0.580
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.577
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.576
t cell lineage commitment GO:0002360 13 0.575
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.574
Mouse
neural nucleus development GO:0048857 22 0.572
Mouse
regulation of calcium ion transport into cytosol GO:0010522 31 0.568
b cell lineage commitment GO:0002326 4 0.567
Mouse
protein insertion into mitochondrial membrane GO:0051204 4 0.567
lymphocyte apoptotic process GO:0070227 54 0.562
negative regulation of retinal cell programmed cell death GO:0046671 2 0.560
Mouse
divalent metal ion transport GO:0070838 172 0.558
b cell homeostasis GO:0001782 34 0.557
muscle cell development GO:0055001 133 0.554
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.554
Worm
guanosine containing compound catabolic process GO:1901069 144 0.553
Worm
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.547
regulation of cysteine type endopeptidase activity GO:2000116 65 0.543
gtp metabolic process GO:0046039 144 0.543
Worm
rhythmic process GO:0048511 174 0.540
cellular ketone metabolic process GO:0042180 84 0.539
response to oxidative stress GO:0006979 123 0.537
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.535
positive regulation of muscle cell differentiation GO:0051149 39 0.534
Mouse
negative regulation of calcium ion transport into cytosol GO:0010523 2 0.532
Mouse
negative regulation of protein modification process GO:0031400 163 0.532
adherens junction assembly GO:0034333 22 0.528
Mouse
protein homooligomerization GO:0051260 43 0.527
cellular response to decreased oxygen levels GO:0036294 18 0.520
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.518
Worm
sequestering of calcium ion GO:0051208 18 0.517
nucleobase containing small molecule metabolic process GO:0055086 352 0.513
Worm
renal tubule morphogenesis GO:0061333 72 0.512
Mouse
positive regulation of nervous system development GO:0051962 221 0.512
Mouse
regulation of peptidase activity GO:0052547 96 0.506
regulation of neuron apoptotic process GO:0043523 122 0.506
regulation of smooth muscle cell migration GO:0014910 6 0.506
Mouse
mitotic cell cycle GO:0000278 195 0.501
Mouse
nucleotide metabolic process GO:0009117 332 0.499
Worm
intrinsic apoptotic signaling pathway GO:0097193 132 0.497
morphogenesis of a branching epithelium GO:0061138 193 0.497
purine ribonucleotide catabolic process GO:0009154 208 0.496
Worm
regulation of hydrolase activity GO:0051336 246 0.496
positive regulation of cellular component biogenesis GO:0044089 94 0.492
Human
female sex differentiation GO:0046660 84 0.491
embryonic digit morphogenesis GO:0042733 56 0.488
post embryonic organ morphogenesis GO:0048563 8 0.485
glycosyl compound metabolic process GO:1901657 246 0.479
Worm
interspecies interaction between organisms GO:0044419 83 0.479
Mouse
regulation of ion homeostasis GO:2000021 64 0.477
cellular response to hypoxia GO:0071456 17 0.476
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.476
Worm
cellular response to oxygen levels GO:0071453 20 0.476
Mouse
regulation of protein stability GO:0031647 52 0.475
Mouse
cation homeostasis GO:0055080 212 0.475
ribonucleoside triphosphate catabolic process GO:0009203 199 0.471
Worm
cellular ion homeostasis GO:0006873 165 0.471
protein localization to membrane GO:0072657 108 0.468
positive regulation of nucleotide metabolic process GO:0045981 114 0.467
Worm
neuron apoptotic process GO:0051402 142 0.465
regulation of lymphocyte apoptotic process GO:0070228 41 0.458
spermatid differentiation GO:0048515 115 0.458
response to cycloheximide GO:0046898 1 0.451
Mouse
regulation of cell cycle process GO:0010564 160 0.449
Mouse
alpha beta t cell lineage commitment GO:0002363 7 0.445
Mouse
divalent inorganic cation transport GO:0072511 178 0.444
negative regulation of phosphorus metabolic process GO:0010563 184 0.440
secondary metabolic process GO:0019748 18 0.440
Mouse
retina development in camera type eye GO:0060041 119 0.438
regulation of mammary gland involution GO:1903519 4 0.438
appendage morphogenesis GO:0035107 149 0.432
pigment metabolic process GO:0042440 32 0.432
Mouse
cell type specific apoptotic process GO:0097285 268 0.430
regulation of cell cycle g1 s phase transition GO:1902806 35 0.430
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.427
response to alkaloid GO:0043279 34 0.425
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.424
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.420
skeletal muscle fiber development GO:0048741 58 0.419
Mouse
mesonephric epithelium development GO:0072163 94 0.418
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.415
t cell proliferation GO:0042098 120 0.414
hair follicle morphogenesis GO:0031069 29 0.414
Mouse
negative regulation of fibroblast proliferation GO:0048147 14 0.413
positive regulation of striated muscle cell differentiation GO:0051155 35 0.413
Mouse
regulation of ion transport GO:0043269 215 0.410
skeletal muscle organ development GO:0060538 163 0.408
Mouse
positive regulation of neuron apoptotic process GO:0043525 25 0.407
development of primary female sexual characteristics GO:0046545 73 0.401
lymphocyte proliferation GO:0046651 164 0.396
activation of cysteine type endopeptidase activity GO:0097202 27 0.392
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.387
Mouse
negative regulation of cell proliferation GO:0008285 296 0.386
pigmentation GO:0043473 71 0.385
positive regulation of striated muscle tissue development GO:0045844 31 0.385
Mouse
response to acid chemical GO:0001101 111 0.381
Mouse
limb development GO:0060173 166 0.381
purine ribonucleoside metabolic process GO:0046128 241 0.378
Worm
glomerulus development GO:0032835 40 0.374
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.373
Worm
regulation of cellular catabolic process GO:0031329 242 0.372
Human Worm
positive regulation of intracellular transport GO:0032388 70 0.371
cell substrate adherens junction assembly GO:0007045 19 0.367
Mouse
calcium ion homeostasis GO:0055074 127 0.366
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.364
negative regulation of neuron apoptotic process GO:0043524 92 0.363
digestive tract morphogenesis GO:0048546 147 0.360
Mouse
response to radiation GO:0009314 165 0.358
viral life cycle GO:0019058 36 0.356
Mouse
germ cell development GO:0007281 185 0.356
kidney morphogenesis GO:0060993 83 0.355
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.352
Worm
meiotic cell cycle GO:0051321 122 0.350
appendage development GO:0048736 166 0.348
forebrain development GO:0030900 302 0.346
purine nucleoside triphosphate metabolic process GO:0009144 226 0.342
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.341
positive regulation of muscle tissue development GO:1901863 32 0.340
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.339
Human Worm
lymphocyte homeostasis GO:0002260 64 0.338
stem cell differentiation GO:0048863 268 0.338
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.337
nephron epithelium development GO:0072009 92 0.336
Mouse
cellular response to oxidative stress GO:0034599 76 0.334
Mouse
negative regulation of cell cycle process GO:0010948 69 0.334
Mouse
cell cycle g1 s phase transition GO:0044843 57 0.332
Mouse
gtp catabolic process GO:0006184 143 0.332
Worm
nephron morphogenesis GO:0072028 69 0.331
Mouse
purine nucleotide metabolic process GO:0006163 302 0.331
Worm
male sex differentiation GO:0046661 109 0.330
purine containing compound metabolic process GO:0072521 311 0.330
Worm
organ growth GO:0035265 117 0.329
Mouse
establishment of protein localization to mitochondrion GO:0072655 11 0.329
ribonucleoside triphosphate metabolic process GO:0009199 220 0.326
Worm
response to oxygen levels GO:0070482 62 0.325
Mouse
response to organonitrogen compound GO:0010243 246 0.325
Mouse
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.321
Mouse
nephron development GO:0072006 109 0.318
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.316
Mouse
ossification GO:0001503 216 0.312
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.310
purine nucleoside metabolic process GO:0042278 241 0.307
Worm
muscle tissue development GO:0060537 308 0.303
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.302
Worm
heterocycle catabolic process GO:0046700 280 0.298
Human Worm
negative regulation of intracellular transport GO:0032387 38 0.297
Mouse
mitochondrion morphogenesis GO:0070584 13 0.295
positive regulation of mammary gland involution GO:1903521 4 0.294
regulation of organ morphogenesis GO:2000027 144 0.292
negative regulation of cytoplasmic transport GO:1903650 29 0.292
Mouse
cellular homeostasis GO:0019725 240 0.290
establishment of protein localization to organelle GO:0072594 118 0.290
adherens junction organization GO:0034332 28 0.286
Mouse
regulation of cellular component size GO:0032535 121 0.281
regulation of skeletal muscle fiber development GO:0048742 36 0.281
Mouse
lymphocyte differentiation GO:0030098 242 0.280
regulation of myotube differentiation GO:0010830 62 0.280
Mouse
ribose phosphate metabolic process GO:0019693 291 0.279
Worm
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 9 0.279
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.279
Mouse
actin filament organization GO:0007015 113 0.278
Mouse
protein localization to mitochondrion GO:0070585 15 0.275
response to amino acid GO:0043200 37 0.274
Mouse
myotube differentiation GO:0014902 105 0.274
Mouse
cellular amine metabolic process GO:0044106 44 0.273
myeloid cell homeostasis GO:0002262 114 0.272
negative regulation of cell cycle GO:0045786 123 0.269
Mouse
peptidyl serine phosphorylation GO:0018105 74 0.269
cellular macromolecule catabolic process GO:0044265 206 0.265
Human
regulation of protein complex assembly GO:0043254 83 0.264
Human
zymogen activation GO:0031638 41 0.261
cellular response to ionizing radiation GO:0071479 11 0.258
Mouse
mesenchymal cell differentiation GO:0048762 107 0.257
Mouse
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.254
Mouse
pallium development GO:0021543 120 0.254
positive regulation of protein modification process GO:0031401 299 0.252
Mouse
t cell apoptotic process GO:0070231 39 0.250
myotube cell development GO:0014904 60 0.249
Mouse
positive regulation of programmed cell death GO:0043068 218 0.247
regulation of muscle tissue development GO:1901861 97 0.246
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.246
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.246
Human Worm
response to hypoxia GO:0001666 58 0.244
Mouse
skin morphogenesis GO:0043589 38 0.239
Mouse
vesicle organization GO:0016050 60 0.238
Mouse
cell substrate adhesion GO:0031589 130 0.237
Mouse
angiogenesis GO:0001525 201 0.235
leukocyte apoptotic process GO:0071887 71 0.234
branching involved in ureteric bud morphogenesis GO:0001658 56 0.231
Mouse
positive regulation of homeostatic process GO:0032846 64 0.230
positive regulation of endopeptidase activity GO:0010950 43 0.230
regulation of cell motility GO:2000145 236 0.230
Mouse
cellular chemical homeostasis GO:0055082 215 0.229
stem cell development GO:0048864 219 0.229
Mouse
blood vessel remodeling GO:0001974 33 0.229
metanephros development GO:0001656 79 0.228
Mouse
response to light stimulus GO:0009416 135 0.226
regulation of cellular ph reduction GO:0032847 2 0.224
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.223
Mouse
leukocyte proliferation GO:0070661 172 0.221
regulation of glycoprotein biosynthetic process GO:0010559 12 0.219
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.218
regulation of organelle organization GO:0033043 289 0.218
Human Worm
cellular response to amino acid stimulus GO:0071230 29 0.217
Mouse
positive regulation of apoptotic process GO:0043065 217 0.217
protein catabolic process GO:0030163 221 0.216
negative regulation of cell growth GO:0030308 44 0.215
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.214
sequestering of metal ion GO:0051238 19 0.209
positive regulation of cell motility GO:2000147 116 0.208
Mouse
negative regulation of anoikis GO:2000811 2 0.205
nuclear division GO:0000280 158 0.202
organelle localization GO:0051640 179 0.202
metencephalon development GO:0022037 89 0.201
Mouse
cell aging GO:0007569 35 0.200
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.200
Worm
positive regulation of growth GO:0045927 104 0.198
Mouse
behavioral fear response GO:0001662 28 0.197
Mouse
melanin metabolic process GO:0006582 12 0.197
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.196
Mouse
homeostasis of number of cells GO:0048872 210 0.196
regulation of cell migration GO:0030334 219 0.195
Mouse
regulation of metal ion transport GO:0010959 106 0.195
regulation of canonical wnt signaling pathway GO:0060828 82 0.193
response to osmotic stress GO:0006970 21 0.193
leukocyte differentiation GO:0002521 342 0.192
regulation of osteoblast proliferation GO:0033688 15 0.190
Mouse
regulation of protein localization GO:0032880 231 0.189
Mouse
modulation by virus of host morphology or physiology GO:0019048 3 0.187
regulation of ossification GO:0030278 112 0.186
Mouse
positive regulation of release of cytochrome c from mitochondria GO:0090200 5 0.185
Human
positive regulation of protein complex assembly GO:0031334 45 0.183
Human
peptidyl serine modification GO:0018209 83 0.181
positive regulation of smooth muscle cell migration GO:0014911 4 0.177
Mouse
striated muscle cell development GO:0055002 125 0.174
Mouse
pigment cell differentiation GO:0050931 27 0.174
Mouse
axonogenesis GO:0007409 274 0.173
Mouse
epithelial tube morphogenesis GO:0060562 303 0.173
neuron maturation GO:0042551 29 0.172
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.171
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.171
multicellular organism growth GO:0035264 161 0.170
Mouse
histone methylation GO:0016571 71 0.167
ribonucleotide catabolic process GO:0009261 208 0.166
Worm
cellular divalent inorganic cation homeostasis GO:0072503 127 0.165
gonad development GO:0008406 141 0.165
protein oligomerization GO:0051259 67 0.164
mitotic cell cycle process GO:1903047 159 0.164
Mouse
regulation of myeloid cell apoptotic process GO:0033032 19 0.163
Mouse
sensory organ morphogenesis GO:0090596 242 0.163
muscle fiber development GO:0048747 76 0.162
Mouse
response to iron ion GO:0010039 4 0.162
regulation of anoikis GO:2000209 2 0.162
regulation of cell substrate adhesion GO:0010810 73 0.161
Mouse
cation transport GO:0006812 399 0.159
ubiquitin dependent protein catabolic process GO:0006511 129 0.159
cell junction assembly GO:0034329 52 0.157
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.155
anatomical structure homeostasis GO:0060249 145 0.154
response to organic cyclic compound GO:0014070 198 0.153
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.153
Worm
post embryonic organ development GO:0048569 17 0.152
neuronal action potential GO:0019228 54 0.151
telencephalon development GO:0021537 186 0.151
b cell proliferation GO:0042100 53 0.150
regulation of multi organism process GO:0043900 111 0.149
Mouse
blood vessel morphogenesis GO:0048514 285 0.148
cellular pigmentation GO:0033059 20 0.147
Mouse
metal ion homeostasis GO:0055065 189 0.146
positive regulation of calcium ion transport GO:0051928 27 0.143
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.140
response to starvation GO:0042594 65 0.138
Mouse
male gonad development GO:0008584 88 0.137
regulation of purine nucleotide catabolic process GO:0033121 122 0.137
Worm
mammary gland epithelium development GO:0061180 65 0.133
genitalia development GO:0048806 37 0.133
glycolipid metabolic process GO:0006664 25 0.133
ribonucleoside catabolic process GO:0042454 206 0.132
Worm
actin polymerization or depolymerization GO:0008154 54 0.130
regulation of mapk cascade GO:0043408 248 0.130
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.129
purine nucleoside catabolic process GO:0006152 205 0.129
Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.129
Mouse
epidermis development GO:0008544 187 0.129
Mouse
myeloid cell apoptotic process GO:0033028 22 0.127
Mouse
organelle fission GO:0048285 170 0.127
Human
actin filament polymerization GO:0030041 44 0.126
homeostasis of number of cells within a tissue GO:0048873 25 0.125
muscle cell migration GO:0014812 19 0.125
Mouse
renal system development GO:0072001 225 0.125
response to inorganic substance GO:0010035 96 0.124
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
peptidyl amino acid modification GO:0018193 336 0.122
ovulation cycle GO:0042698 59 0.122
regulation of calcium ion transport GO:0051924 69 0.121
hindbrain development GO:0030902 128 0.121
Mouse
cellular lipid metabolic process GO:0044255 323 0.120
membrane lipid metabolic process GO:0006643 53 0.119
macromolecule catabolic process GO:0009057 281 0.119
Human
neuron migration GO:0001764 122 0.119
cell adhesion GO:0007155 329 0.118
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.118
smooth muscle cell migration GO:0014909 10 0.117
Mouse
liposaccharide metabolic process GO:1903509 27 0.117
striated muscle tissue development GO:0014706 293 0.116
Mouse
multicellular organismal homeostasis GO:0048871 164 0.116
alpha beta t cell differentiation GO:0046632 69 0.115
Mouse
necrotic cell death GO:0070265 30 0.115
cellular calcium ion homeostasis GO:0006874 119 0.114
negative regulation of molecular function GO:0044092 258 0.113
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.112
behavioral defense response GO:0002209 28 0.111
Mouse

Bax disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.551
Human
disease of cellular proliferation DOID:14566 0 0.551
Human