Mus musculus

197 known processes

Bbs2

Bardet-Biedl syndrome 2 (human)

(Aliases: 2410125H22Rik,AI447581)

Bbs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cilium assembly GO:1902017 7 1.000
regulation of cilium movement GO:0003352 6 1.000
intraciliary retrograde transport GO:0035721 3 1.000
establishment of melanosome localization GO:0032401 11 1.000
Zebrafish
cilium assembly GO:0042384 81 1.000
cilium or flagellum dependent cell motility GO:0001539 6 0.999
melanosome localization GO:0032400 12 0.998
Zebrafish
regulation of cilium beat frequency involved in ciliary motility GO:0060296 5 0.998
cellular response to leptin stimulus GO:0044320 6 0.998
nonmotile primary cilium assembly GO:0035058 8 0.996
Worm
cilium movement involved in cell motility GO:0060294 5 0.996
cilium dependent cell motility GO:0060285 6 0.994
cilium morphogenesis GO:0060271 102 0.991
microtubule based movement GO:0007018 84 0.991
microtubule anchoring at microtubule organizing center GO:0072393 5 0.988
pigment granule localization GO:0051875 13 0.986
Zebrafish
regulation of cilium dependent cell motility GO:1902019 5 0.986
cellular component assembly involved in morphogenesis GO:0010927 139 0.981
intraciliary transport GO:0042073 9 0.977
regulation of microtubule based movement GO:0060632 8 0.975
regulation of cilium movement involved in cell motility GO:0060295 5 0.970
fat cell differentiation GO:0045444 160 0.962
cilium movement GO:0003341 28 0.938
response to leptin GO:0044321 7 0.921
organelle assembly GO:0070925 177 0.921
cytoskeleton dependent intracellular transport GO:0030705 50 0.876
striatum development GO:0021756 14 0.867
eye photoreceptor cell differentiation GO:0001754 41 0.864
melanosome transport GO:0032402 11 0.852
Zebrafish
establishment of vesicle localization GO:0051650 81 0.850
Zebrafish
photoreceptor cell maintenance GO:0045494 19 0.828
photoreceptor cell differentiation GO:0046530 52 0.785
retina homeostasis GO:0001895 23 0.753
mitotic cytokinesis GO:0000281 4 0.742
microtubule based transport GO:0010970 50 0.740
maintenance of protein location in nucleus GO:0051457 2 0.713
negative regulation of systemic arterial blood pressure GO:0003085 15 0.702
axis elongation involved in somitogenesis GO:0090245 4 0.679
regulation of response to food GO:0032095 10 0.674
photoreceptor cell development GO:0042461 40 0.649
eye photoreceptor cell development GO:0042462 31 0.556
negative regulation of appetite GO:0032099 7 0.556
forebrain development GO:0030900 302 0.551
retinal rod cell development GO:0046548 10 0.533
sensory perception of smell GO:0007608 26 0.508
regulation of cell division GO:0051302 76 0.491
organelle localization GO:0051640 179 0.489
Zebrafish
regulation of appetite GO:0032098 12 0.483
spermatid development GO:0007286 108 0.475
cellular pigmentation GO:0033059 20 0.474
Zebrafish
smoothened signaling pathway GO:0007224 105 0.470
response to food GO:0032094 17 0.468
establishment of organelle localization GO:0051656 122 0.459
Zebrafish
pallium development GO:0021543 120 0.456
regulation of microtubule based process GO:0032886 52 0.450
regionalization GO:0003002 337 0.446
microtubule based process GO:0007017 236 0.429
spermatid differentiation GO:0048515 115 0.420
sensory organ morphogenesis GO:0090596 242 0.414
telencephalon development GO:0021537 186 0.410
embryonic organ morphogenesis GO:0048562 276 0.410
embryonic epithelial tube formation GO:0001838 130 0.395
spermatogenesis GO:0007283 284 0.385
epithelial tube formation GO:0072175 130 0.380
tube closure GO:0060606 91 0.360
brain morphogenesis GO:0048854 32 0.352
primary neural tube formation GO:0014020 95 0.348
morphogenesis of embryonic epithelium GO:0016331 159 0.345
multicellular organism growth GO:0035264 161 0.344
cytokine mediated signaling pathway GO:0019221 115 0.339
cerebral cortex development GO:0021987 86 0.339
neural tube closure GO:0001843 90 0.321
regulation of systemic arterial blood pressure GO:0003073 61 0.308
regulation of organelle assembly GO:1902115 19 0.305
adult behavior GO:0030534 135 0.302
protein localization to microtubule cytoskeleton GO:0072698 8 0.300
protein localization to organelle GO:0033365 185 0.293
limbic system development GO:0021761 72 0.290
sensory perception of chemical stimulus GO:0007606 51 0.289
epithelial tube morphogenesis GO:0060562 303 0.278
skeletal system development GO:0001501 356 0.268
notch signaling pathway GO:0007219 71 0.261
positive regulation of cellular component biogenesis GO:0044089 94 0.251
developmental pigmentation GO:0048066 40 0.241
negative regulation of blood pressure GO:0045776 22 0.241
neural tube development GO:0021915 160 0.233
negative regulation of response to food GO:0032096 7 0.232
tube formation GO:0035148 140 0.228
pigment metabolic process GO:0042440 32 0.226
hippocampus development GO:0021766 52 0.224
appendage development GO:0048736 166 0.217
dendrite development GO:0016358 115 0.217
circulatory system process GO:0003013 197 0.207
convergent extension GO:0060026 14 0.200
eye pigmentation GO:0048069 3 0.199
sensory perception GO:0007600 245 0.199
maintenance of protein localization in organelle GO:0072595 2 0.195
positive regulation of cell projection organization GO:0031346 95 0.171
subpallium development GO:0021544 20 0.170
centrosome organization GO:0051297 26 0.167
protein localization to nucleus GO:0034504 121 0.167
determination of left right symmetry GO:0007368 80 0.166
Zebrafish
positive regulation of organelle organization GO:0010638 128 0.162
photoreceptor cell morphogenesis GO:0008594 3 0.162
regulation of notch signaling pathway GO:0008593 35 0.161
mitotic cell cycle process GO:1903047 159 0.157
positive regulation of organelle assembly GO:1902117 8 0.154
heart morphogenesis GO:0003007 178 0.154
blood circulation GO:0008015 195 0.153
tissue homeostasis GO:0001894 115 0.151
digestive tract development GO:0048565 190 0.150
Zebrafish
cellular response to cytokine stimulus GO:0071345 189 0.148
segmentation GO:0035282 93 0.147
limb development GO:0060173 166 0.144
axis elongation GO:0003401 30 0.143
mitotic cell cycle GO:0000278 195 0.141
microtubule anchoring at centrosome GO:0034454 3 0.137
photoreceptor cell outer segment organization GO:0035845 5 0.134
protein localization to cytoskeleton GO:0044380 9 0.133
multicellular organismal homeostasis GO:0048871 164 0.130
developmental growth involved in morphogenesis GO:0060560 138 0.130
cellular response to hormone stimulus GO:0032870 150 0.129
germ cell development GO:0007281 185 0.126
maintenance of location GO:0051235 89 0.126
anatomical structure homeostasis GO:0060249 145 0.126
somitogenesis GO:0001756 69 0.122
regulation of cell projection assembly GO:0060491 38 0.122
regulation of organelle organization GO:0033043 289 0.122
regulation of lipid metabolic process GO:0019216 118 0.120
regulation of blood pressure GO:0008217 93 0.119
regulation of cytokinesis GO:0032465 5 0.118
microtubule organizing center organization GO:0031023 28 0.118
gastrulation GO:0007369 116 0.117
Zebrafish
regulation of cell cycle GO:0051726 281 0.112
response to nutrient levels GO:0031667 109 0.109
vesicle localization GO:0051648 86 0.106
Zebrafish
embryonic heart tube morphogenesis GO:0003143 51 0.103
microtubule cytoskeleton organization GO:0000226 157 0.102
positive regulation of growth GO:0045927 104 0.101
ubiquitin dependent protein catabolic process GO:0006511 129 0.094
regulation of cell projection organization GO:0031344 206 0.093
somite development GO:0061053 81 0.088
regulation of cellular component biogenesis GO:0044087 181 0.088
cellular macromolecule catabolic process GO:0044265 206 0.087
microtubule anchoring GO:0034453 9 0.086
determination of heart left right asymmetry GO:0061371 48 0.086
embryonic heart tube development GO:0035050 65 0.085
maintenance of location in cell GO:0051651 24 0.082
digestive system development GO:0055123 200 0.080
Zebrafish
response to extracellular stimulus GO:0009991 127 0.079
macromolecule catabolic process GO:0009057 281 0.075
cellular lipid metabolic process GO:0044255 323 0.073
ventricular system development GO:0021591 27 0.068
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.067
protein catabolic process GO:0030163 221 0.065
neural precursor cell proliferation GO:0061351 121 0.064
olfactory learning GO:0008355 2 0.064
cellular protein catabolic process GO:0044257 155 0.061
cellular amino acid metabolic process GO:0006520 103 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
maintenance of protein location in cell GO:0032507 20 0.055
renal tubule development GO:0061326 87 0.055
regulation of cell motility GO:2000145 236 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.050
positive regulation of cellular catabolic process GO:0031331 148 0.049
amine metabolic process GO:0009308 45 0.048
proteasomal protein catabolic process GO:0010498 98 0.048
modification dependent protein catabolic process GO:0019941 133 0.048
modification dependent macromolecule catabolic process GO:0043632 133 0.046
palate development GO:0060021 76 0.046
positive regulation of proteolysis GO:0045862 85 0.045
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.045
positive regulation of protein catabolic process GO:0045732 60 0.045
pigment granule transport GO:0051904 12 0.043
Zebrafish
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.043
negative regulation of cell proliferation GO:0008285 296 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
urogenital system development GO:0001655 261 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
establishment of anatomical structure orientation GO:0048560 1 0.039
pigmentation GO:0043473 71 0.037
Zebrafish
hormone metabolic process GO:0042445 86 0.037
regulation of smoothened signaling pathway GO:0008589 58 0.036
neural retina development GO:0003407 41 0.035
cellular amine metabolic process GO:0044106 44 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.032
cellular ketone metabolic process GO:0042180 84 0.031
regulation of proteolysis GO:0030162 164 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of cellular protein catabolic process GO:1903362 61 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
kidney development GO:0001822 213 0.030
regulation of hormone levels GO:0010817 211 0.030
heterocycle catabolic process GO:0046700 280 0.030
skin development GO:0043588 220 0.029
positive regulation of cellular protein catabolic process GO:1903364 34 0.029
retina development in camera type eye GO:0060041 119 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
regulation of protein catabolic process GO:0042176 108 0.028
olfactory lobe development GO:0021988 32 0.026
cellular protein complex assembly GO:0043623 116 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
dna metabolic process GO:0006259 303 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
purine containing compound metabolic process GO:0072521 311 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
response to organonitrogen compound GO:0010243 246 0.021
cell adhesion GO:0007155 329 0.021
regulation of proteasomal protein catabolic process GO:0061136 46 0.021
regulation of protein localization GO:0032880 231 0.021
purine nucleoside metabolic process GO:0042278 241 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.019
muscle tissue development GO:0060537 308 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
positive regulation of cell death GO:0010942 224 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
neuronal action potential GO:0019228 54 0.018
striated muscle tissue development GO:0014706 293 0.018
dna repair GO:0006281 107 0.018
homeostasis of number of cells GO:0048872 210 0.018
epidermis development GO:0008544 187 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
sensory perception of light stimulus GO:0050953 54 0.017
membrane organization GO:0061024 245 0.017
apoptotic signaling pathway GO:0097190 306 0.017
immune effector process GO:0002252 321 0.017
inclusion body assembly GO:0070841 3 0.017
olfactory behavior GO:0042048 7 0.017
cartilage development GO:0051216 140 0.017
sensory perception of sound GO:0007605 97 0.017
ras protein signal transduction GO:0007265 77 0.017
peptidyl amino acid modification GO:0018193 336 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
wnt signaling pathway GO:0016055 188 0.017
action potential GO:0001508 78 0.016
negative regulation of protein modification process GO:0031400 163 0.016
renal system development GO:0072001 225 0.016
male gamete generation GO:0048232 285 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
camera type eye development GO:0043010 266 0.016
nucleotide metabolic process GO:0009117 332 0.015
transmembrane transport GO:0055085 412 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
regulation of cell activation GO:0050865 289 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
oocyte axis specification GO:0007309 2 0.015
aromatic compound catabolic process GO:0019439 286 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
asymmetric stem cell division GO:0098722 3 0.015
muscle cell differentiation GO:0042692 261 0.015
axoneme assembly GO:0035082 15 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.014
regulation of homeostatic process GO:0032844 182 0.014
cation transport GO:0006812 399 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
nuclear division GO:0000280 158 0.014
protein acylation GO:0043543 64 0.014
transmission of nerve impulse GO:0019226 76 0.014
organophosphate catabolic process GO:0046434 232 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
innate immune response in mucosa GO:0002227 3 0.014
b cell activation GO:0042113 161 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.014
protein ubiquitination GO:0016567 171 0.014
purine containing compound catabolic process GO:0072523 213 0.014
fertilization GO:0009566 127 0.014
associative learning GO:0008306 61 0.014
methylation GO:0032259 134 0.014
regulation of cell adhesion GO:0030155 154 0.013
skeletal muscle organ development GO:0060538 163 0.013
regulation of membrane potential GO:0042391 192 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
learning or memory GO:0007611 148 0.013
regulation of neuron differentiation GO:0045664 281 0.013
negative regulation of immune system process GO:0002683 209 0.013
actin cytoskeleton organization GO:0030036 220 0.013
protein localization to membrane GO:0072657 108 0.013
bone development GO:0060348 120 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
skeletal system morphogenesis GO:0048705 203 0.013
multicellular organismal signaling GO:0035637 91 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
neuron projection guidance GO:0097485 141 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
nucleoside metabolic process GO:0009116 246 0.013
cation transmembrane transport GO:0098655 266 0.013
covalent chromatin modification GO:0016569 163 0.013
leukocyte differentiation GO:0002521 342 0.013
regulation of transferase activity GO:0051338 263 0.013
protein maturation GO:0051604 176 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
negative regulation of molecular function GO:0044092 258 0.012
response to organic cyclic compound GO:0014070 198 0.012
response to radiation GO:0009314 165 0.012
oxidation reduction process GO:0055114 342 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.012
cytoplasmic transport GO:0016482 234 0.012
negative regulation of nervous system development GO:0051961 156 0.012
rho protein signal transduction GO:0007266 32 0.012
epithelial cell proliferation GO:0050673 174 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
protein processing GO:0016485 163 0.012
cell fate commitment GO:0045165 210 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
neural tube formation GO:0001841 108 0.012
positive regulation of nervous system development GO:0051962 221 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
dephosphorylation GO:0016311 129 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
lymphocyte differentiation GO:0030098 242 0.012
learning GO:0007612 98 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.011
myelination GO:0042552 74 0.011
organelle fission GO:0048285 170 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
cognition GO:0050890 149 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
response to growth factor GO:0070848 198 0.011
stem cell differentiation GO:0048863 268 0.011
regulation of hydrolase activity GO:0051336 246 0.011
lipid biosynthetic process GO:0008610 179 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
asymmetric neuroblast division GO:0055059 1 0.011
chromatin modification GO:0016568 187 0.011
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of protein complex assembly GO:0043254 83 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
nitrogen compound transport GO:0071705 271 0.011
nucleotide catabolic process GO:0009166 217 0.011
erythrocyte differentiation GO:0030218 88 0.011
rna processing GO:0006396 105 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
chromatin organization GO:0006325 206 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
mrna metabolic process GO:0016071 84 0.011
inflammatory response GO:0006954 244 0.010
positive regulation of cell development GO:0010720 237 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
cell substrate adhesion GO:0031589 130 0.010
embryonic limb morphogenesis GO:0030326 126 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
regulation of chromosome organization GO:0033044 83 0.010
regulation of binding GO:0051098 111 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
muscle contraction GO:0006936 101 0.010
stem cell development GO:0048864 219 0.010
regulation of neuron death GO:1901214 134 0.010
cellular response to lipid GO:0071396 145 0.010
intracellular protein transport GO:0006886 204 0.010
gtp metabolic process GO:0046039 144 0.010

Bbs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.030
sensory system disease DOID:0050155 0 0.030
disease of anatomical entity DOID:7 0 0.030
eye and adnexa disease DOID:1492 0 0.030
nervous system disease DOID:863 0 0.030
eye disease DOID:5614 0 0.030
musculoskeletal system disease DOID:17 0 0.012
retinal degeneration DOID:8466 0 0.010
retinitis pigmentosa DOID:10584 0 0.010