Mus musculus

0 known processes

Blk

B lymphoid kinase

Blk biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.885
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.885
Human Mouse
immune response activating signal transduction GO:0002757 116 0.865
Human Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.851
Human Mouse
activation of immune response GO:0002253 138 0.822
Human Mouse
immune response regulating signaling pathway GO:0002764 125 0.778
Human Mouse
positive regulation of cytokine production GO:0001819 174 0.772
Mouse
regulation of cytokine production GO:0001817 266 0.756
Mouse
regulation of defense response GO:0031347 233 0.729
Mouse
cytokine secretion GO:0050663 72 0.663
Mouse
glial cell differentiation GO:0010001 131 0.660
regulation of lymphocyte activation GO:0051249 240 0.656
Mouse
adaptive immune response GO:0002250 155 0.636
Mouse
inflammatory response GO:0006954 244 0.626
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.603
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.592
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.569
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.568
regulation of mapk cascade GO:0043408 248 0.561
Mouse
innate immune response GO:0045087 157 0.556
Mouse
regulation of t cell costimulation GO:2000523 2 0.552
negative regulation of eosinophil degranulation GO:0043310 1 0.551
monocyte extravasation GO:0035696 2 0.551
negative regulation of immune system process GO:0002683 209 0.535
Mouse
eosinophil activation GO:0043307 1 0.524
regulation of response to wounding GO:1903034 189 0.521
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.520
positive regulation of immunological synapse formation GO:2000522 1 0.509
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.508
cation transport GO:0006812 399 0.499
Mouse
positive regulation of secretion GO:0051047 130 0.496
Human Mouse
cytokine biosynthetic process GO:0042089 68 0.480
sequestering of calcium ion GO:0051208 18 0.473
Mouse
defense response to other organism GO:0098542 197 0.464
Mouse
helper t cell chemotaxis GO:0035704 1 0.463
antigen processing and presentation GO:0019882 47 0.453
regulation of eosinophil degranulation GO:0043309 1 0.450
regulation of cytokine secretion GO:0050707 61 0.442
Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.439
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.436
microglial cell activation involved in immune response GO:0002282 1 0.433
immune effector process GO:0002252 321 0.433
Mouse
leukocyte mediated immunity GO:0002443 174 0.419
Mouse
leukocyte differentiation GO:0002521 342 0.413
Mouse
tumor necrosis factor production GO:0032640 50 0.411
regulation of inflammatory response GO:0050727 147 0.409
Mouse
positive regulation of mapk cascade GO:0043410 170 0.393
Mouse
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.384
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.384
leukocyte proliferation GO:0070661 172 0.375
Mouse
defense response to bacterium GO:0042742 119 0.369
Mouse
regulation of monocyte extravasation GO:2000437 2 0.367
positive regulation of cell activation GO:0050867 158 0.366
Mouse
t cell extravasation GO:0072683 4 0.366
positive regulation of t cell activation GO:0050870 101 0.363
Mouse
response to molecule of bacterial origin GO:0002237 143 0.356
Mouse
regulation of adaptive immune response GO:0002819 90 0.354
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.354
divalent inorganic cation transport GO:0072511 178 0.354
Mouse
action potential GO:0001508 78 0.354
lymphocyte proliferation GO:0046651 164 0.351
Mouse
calcium ion transport GO:0006816 159 0.348
Mouse
detection of bacterium GO:0016045 7 0.342
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.342
gliogenesis GO:0042063 141 0.340
positive regulation of cytokine biosynthetic process GO:0042108 40 0.338
detection of other organism GO:0098543 8 0.335
regulation of secretion GO:0051046 274 0.332
Human Mouse
regulation of leukocyte proliferation GO:0070663 121 0.331
Mouse
regulation of immunological synapse formation GO:2000520 2 0.330
regulation of t cell extravasation GO:2000407 3 0.329
regulation of cell activation GO:0050865 289 0.318
Mouse
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.318
multicellular organismal signaling GO:0035637 91 0.308
hematopoietic stem cell migration GO:0035701 1 0.306
mapk cascade GO:0000165 281 0.302
Mouse
cell recognition GO:0008037 83 0.296
lymphocyte differentiation GO:0030098 242 0.293
Mouse
regulation of endocytosis GO:0030100 69 0.289
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.289
Mouse
positive regulation of inflammatory response GO:0050729 47 0.288
eosinophil activation involved in immune response GO:0002278 1 0.287
positive regulation of lymphocyte activation GO:0051251 140 0.285
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.285
forebrain development GO:0030900 302 0.284
Mouse
cellular response to lipid GO:0071396 145 0.284
Mouse
negative regulation of cell activation GO:0050866 111 0.283
Mouse
immune complex clearance GO:0002434 2 0.273
leukocyte degranulation GO:0043299 27 0.271
Mouse
transmission of nerve impulse GO:0019226 76 0.267
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.265
neuronal action potential GO:0019228 54 0.260
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.256
positive regulation of protein secretion GO:0050714 52 0.254
Mouse
b cell proliferation GO:0042100 53 0.251
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.247
regulation of t cell activation GO:0050863 170 0.247
Mouse
positive regulation of t cell extravasation GO:2000409 2 0.244
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.237
positive regulation of monocyte extravasation GO:2000439 1 0.235
i kappab kinase nf kappab signaling GO:0007249 85 0.234
Mouse
membrane organization GO:0061024 245 0.230
regulation of cytokine biosynthetic process GO:0042035 59 0.228
positive regulation of tumor necrosis factor production GO:0032760 30 0.225
tumor necrosis factor biosynthetic process GO:0042533 10 0.225
wound healing GO:0042060 157 0.225
Mouse
exocytosis GO:0006887 121 0.225
Mouse
cation homeostasis GO:0055080 212 0.224
Mouse
positive regulation of defense response GO:0031349 124 0.222
Mouse
sequestering of metal ion GO:0051238 19 0.221
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.217
negative regulation of cell proliferation GO:0008285 296 0.211
Mouse
positive regulation of secretion by cell GO:1903532 114 0.210
Human Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.209
Mouse
lymphocyte mediated immunity GO:0002449 139 0.206
t helper 17 cell chemotaxis GO:0035705 1 0.199
positive regulation of innate immune response GO:0045089 80 0.197
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.197
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.197
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.196
thymic t cell selection GO:0045061 22 0.192
regulation of phagocytosis GO:0050764 33 0.188
Mouse
calcium ion transport into cytosol GO:0060402 48 0.188
Mouse
positive regulation of response to wounding GO:1903036 66 0.187
morphogenesis of a branching structure GO:0001763 203 0.186
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.184
metal ion homeostasis GO:0055065 189 0.184
Mouse
phagocytosis GO:0006909 66 0.183
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.182
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.180
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.179
negative regulation of homeostatic process GO:0032845 71 0.176
Mouse
activation of innate immune response GO:0002218 56 0.174
Mouse
protein secretion GO:0009306 111 0.171
Mouse
cellular ketone metabolic process GO:0042180 84 0.171
chemokine mediated signaling pathway GO:0070098 17 0.170
cell killing GO:0001906 67 0.169
mature dendritic cell differentiation GO:0097029 3 0.164
positive regulation of leukocyte mediated immunity GO:0002705 70 0.163
Mouse
detection of external biotic stimulus GO:0098581 9 0.162
maintenance of location GO:0051235 89 0.162
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.158
detection of fungus GO:0016046 2 0.157
response to lipopolysaccharide GO:0032496 128 0.157
Mouse
regulation of metal ion transport GO:0010959 106 0.156
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.153
Human Mouse
interleukin 12 secretion GO:0072610 3 0.151
regulation of exocytosis GO:0017157 61 0.147
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.145
Mouse
negative regulation of immune effector process GO:0002698 55 0.144
single organismal cell cell adhesion GO:0016337 131 0.142
Mouse Fly
interferon gamma production GO:0032609 67 0.142
Mouse
negative regulation of defense response GO:0031348 77 0.142
cytokine metabolic process GO:0042107 71 0.139
ensheathment of neurons GO:0007272 76 0.138
regulation of hematopoietic stem cell migration GO:2000471 1 0.136
cellular extravasation GO:0045123 17 0.136
hemostasis GO:0007599 78 0.136
Mouse
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.135
regulation of ion homeostasis GO:2000021 64 0.135
Mouse
regulation of dendritic cell chemotaxis GO:2000508 1 0.134
regulation of interferon gamma production GO:0032649 57 0.133
telencephalon development GO:0021537 186 0.132
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.131
glycoprotein biosynthetic process GO:0009101 89 0.129
positive regulation of cell migration GO:0030335 109 0.129
Mouse
regulation of body fluid levels GO:0050878 162 0.127
Mouse
blood coagulation GO:0007596 76 0.127
Mouse
eosinophil degranulation GO:0043308 1 0.126
synaptic transmission GO:0007268 329 0.126
Fly
cellular calcium ion homeostasis GO:0006874 119 0.126
Mouse
homeostasis of number of cells GO:0048872 210 0.124
Mouse
eosinophil mediated immunity GO:0002447 1 0.123
neural precursor cell proliferation GO:0061351 121 0.121
b cell activation GO:0042113 161 0.121
Mouse
cellular amino acid metabolic process GO:0006520 103 0.119
muscle tissue development GO:0060537 308 0.119
negative thymic t cell selection GO:0045060 12 0.119
positive regulation of interferon gamma production GO:0032729 39 0.116
positive regulation of cell development GO:0010720 237 0.116
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.116
regulation of leukocyte apoptotic process GO:2000106 56 0.115
Mouse
coagulation GO:0050817 78 0.114
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.114
Mouse
t cell differentiation in thymus GO:0033077 77 0.113
regulation of protein serine threonine kinase activity GO:0071900 157 0.112
Mouse
positive regulation of immune effector process GO:0002699 107 0.112
Mouse
regulation of secretion by cell GO:1903530 249 0.112
Human Mouse
angiogenesis GO:0001525 201 0.111
cell type specific apoptotic process GO:0097285 268 0.111
Mouse
alpha beta t cell activation GO:0046631 91 0.110
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.108
interleukin 2 production GO:0032623 33 0.108
ameboidal type cell migration GO:0001667 128 0.108
inflammatory response to antigenic stimulus GO:0002437 30 0.107
endocytosis GO:0006897 168 0.107
Mouse
cell adhesion GO:0007155 329 0.107
Mouse Fly
cellular response to biotic stimulus GO:0071216 92 0.104
Mouse
divalent metal ion transport GO:0070838 172 0.104
Mouse
regulation of map kinase activity GO:0043405 120 0.104
Mouse
positive regulation of phagocytosis GO:0050766 26 0.103
regulation of acute inflammatory response GO:0002673 27 0.102
extrinsic apoptotic signaling pathway GO:0097191 126 0.102
cellular chemical homeostasis GO:0055082 215 0.102
Mouse
response to bacterial lipoprotein GO:0032493 4 0.099
detection of stimulus GO:0051606 84 0.099
Mouse
regulation of homeostatic process GO:0032844 182 0.098
Mouse
positive regulation of protein modification process GO:0031401 299 0.096
Mouse Fly
positive regulation of adaptive immune response GO:0002821 61 0.096
antigen processing and presentation of exogenous antigen GO:0019884 26 0.096
microglial cell activation GO:0001774 3 0.096
positive regulation of monocyte chemotaxis GO:0090026 2 0.095
t cell differentiation GO:0030217 174 0.095
Mouse
t cell activation GO:0042110 289 0.095
Mouse
regulation of interleukin 1 production GO:0032652 26 0.095
production of molecular mediator of immune response GO:0002440 103 0.095
regulation of b cell proliferation GO:0030888 39 0.095
Mouse
wnt signaling pathway GO:0016055 188 0.094
Mouse
epithelial cell proliferation GO:0050673 174 0.093
regulation of kinase activity GO:0043549 249 0.093
Mouse Fly
positive regulation of ion transport GO:0043270 65 0.093
myelination GO:0042552 74 0.092
acute inflammatory response to antigenic stimulus GO:0002438 12 0.092
regulation of blood coagulation GO:0030193 28 0.091
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.090
cell activation involved in immune response GO:0002263 126 0.090
Mouse
cellular amine metabolic process GO:0044106 44 0.090
acute inflammatory response GO:0002526 41 0.090
tissue remodeling GO:0048771 102 0.089
Mouse
myeloid cell activation involved in immune response GO:0002275 34 0.088
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.087
b cell mediated immunity GO:0019724 71 0.087
humoral immune response GO:0006959 57 0.086
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.086
regulation of cell motility GO:2000145 236 0.085
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.084
regulation of cell migration GO:0030334 219 0.084
Mouse
cerebral cortex development GO:0021987 86 0.084
lymphocyte activation involved in immune response GO:0002285 93 0.084
cell fate commitment GO:0045165 210 0.083
Worm
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.082
Mouse
cytosolic calcium ion transport GO:0060401 48 0.082
Mouse
regulation of t cell proliferation GO:0042129 92 0.081
bone resorption GO:0045453 38 0.080
Mouse
cellular homeostasis GO:0019725 240 0.079
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.078
negative regulation of t cell activation GO:0050868 65 0.077
cellular metal ion homeostasis GO:0006875 151 0.076
Mouse
digestive tract development GO:0048565 190 0.075
Mouse Worm
reactive nitrogen species metabolic process GO:2001057 0 0.075
sensory perception GO:0007600 245 0.075
Mouse
oligodendrocyte differentiation GO:0048709 53 0.075
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.074
axon ensheathment GO:0008366 76 0.074
innate immune response activating signal transduction GO:0002758 50 0.073
Mouse
epidermis development GO:0008544 187 0.072
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
positive regulation of lymphocyte proliferation GO:0050671 70 0.072
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.072
respiratory system development GO:0060541 190 0.071
Fly
apoptotic signaling pathway GO:0097190 306 0.071
regulation of membrane potential GO:0042391 192 0.071
positive regulation of leukocyte proliferation GO:0070665 73 0.071
leukocyte migration GO:0050900 124 0.070
cellular divalent inorganic cation homeostasis GO:0072503 127 0.070
Mouse
positive regulation of interleukin 2 production GO:0032743 19 0.069
embryonic placenta development GO:0001892 98 0.069
cellular lipid metabolic process GO:0044255 323 0.069
Mouse
positive regulation of programmed cell death GO:0043068 218 0.068
Mouse
stem cell development GO:0048864 219 0.068
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.067
multicellular organismal homeostasis GO:0048871 164 0.067
Mouse
erythrocyte differentiation GO:0030218 88 0.066
Mouse
response to molecule of fungal origin GO:0002238 4 0.065
detection of biotic stimulus GO:0009595 10 0.065
regulation of interleukin 8 production GO:0032677 3 0.065
cognition GO:0050890 149 0.065
Fly
defense response to gram positive bacterium GO:0050830 50 0.065
Mouse
heart morphogenesis GO:0003007 178 0.065
negative regulation of leukocyte mediated immunity GO:0002704 29 0.064
gamma delta t cell lineage commitment GO:0002365 1 0.064
myeloid leukocyte activation GO:0002274 83 0.064
Mouse
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.064
interleukin 1 beta production GO:0032611 30 0.064
stem cell differentiation GO:0048863 268 0.064
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.063
regulation of interleukin 2 production GO:0032663 28 0.063
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.063
t cell receptor signaling pathway GO:0050852 46 0.062
Mouse
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.062
regulation of protein kinase activity GO:0045859 232 0.062
Mouse Fly
monocarboxylic acid metabolic process GO:0032787 191 0.061
t cell selection GO:0045058 34 0.061
positive regulation of kinase activity GO:0033674 155 0.061
Mouse Fly
regulation of hypersensitivity GO:0002883 10 0.061
learning GO:0007612 98 0.061
Fly
positive regulation of acute inflammatory response GO:0002675 16 0.061
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.060
detection of yeast GO:0001879 2 0.060
regulation of cellular response to stress GO:0080135 159 0.060
regulation of gliogenesis GO:0014013 50 0.060
positive regulation of cell motility GO:2000147 116 0.060
Mouse
glial cell development GO:0021782 54 0.060
regulation of neuron differentiation GO:0045664 281 0.059
Mouse
mitotic cell cycle process GO:1903047 159 0.059
Worm
cytosolic calcium ion homeostasis GO:0051480 70 0.059
Mouse
calcium ion homeostasis GO:0055074 127 0.059
Mouse
positive regulation of protein transport GO:0051222 93 0.059
Mouse
jnk cascade GO:0007254 72 0.059
positive regulation of cell death GO:0010942 224 0.059
Mouse
positive regulation of apoptotic process GO:0043065 217 0.059
Mouse
lipid biosynthetic process GO:0008610 179 0.059
regulation of organelle organization GO:0033043 289 0.058
Mouse Fly
negative regulation of lymphocyte activation GO:0051250 91 0.058
Mouse
positive regulation of jnk cascade GO:0046330 46 0.058
signal transduction in absence of ligand GO:0038034 55 0.058
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.058
locomotory behavior GO:0007626 195 0.058
granulocyte activation GO:0036230 10 0.058
interleukin 6 production GO:0032635 58 0.057
interleukin 8 secretion GO:0072606 3 0.057
myeloid cell differentiation GO:0030099 233 0.056
Mouse
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.056
Mouse
regulation of leukocyte degranulation GO:0043300 20 0.056
Mouse
pallium development GO:0021543 120 0.055
blood vessel morphogenesis GO:0048514 285 0.055
regulation of interleukin 8 secretion GO:2000482 2 0.055
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.055
Mouse
negative regulation of exocytosis GO:0045920 12 0.054
positive regulation of interferon alpha production GO:0032727 4 0.054
fatty acid biosynthetic process GO:0006633 41 0.054
organic hydroxy compound metabolic process GO:1901615 203 0.054
glycoprotein metabolic process GO:0009100 116 0.053
forebrain cell migration GO:0021885 58 0.053
response to acid chemical GO:0001101 111 0.053
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.053
Mouse
single fertilization GO:0007338 82 0.053
toll like receptor signaling pathway GO:0002224 38 0.052
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.052
Mouse
interleukin 8 production GO:0032637 4 0.052
hypersensitivity GO:0002524 10 0.052
immunoglobulin mediated immune response GO:0016064 69 0.051
microtubule based process GO:0007017 236 0.051
Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.051
cellular response to lipopolysaccharide GO:0071222 77 0.050
Mouse
small molecule biosynthetic process GO:0044283 132 0.050
regulation of monocyte chemotaxis GO:0090025 3 0.050
endomembrane system organization GO:0010256 147 0.050
cytokine mediated signaling pathway GO:0019221 115 0.049
alpha beta t cell proliferation GO:0046633 21 0.048
b cell activation involved in immune response GO:0002312 50 0.048
peptidyl amino acid modification GO:0018193 336 0.048
Human Mouse Worm Fly
b cell differentiation GO:0030183 78 0.048
organelle localization GO:0051640 179 0.048
Mouse Worm
regulation of mast cell activation involved in immune response GO:0033006 17 0.048
Mouse
regulation of glial cell differentiation GO:0045685 41 0.047
regulation of establishment of protein localization GO:0070201 181 0.047
Mouse
regulated secretory pathway GO:0045055 32 0.047
Mouse
renal system development GO:0072001 225 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
lymphocyte apoptotic process GO:0070227 54 0.047
Mouse
interleukin 1 production GO:0032612 31 0.047
response to extracellular stimulus GO:0009991 127 0.047
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.047
negative regulation of leukocyte proliferation GO:0070664 46 0.047
Mouse
carbohydrate homeostasis GO:0033500 128 0.046
positive regulation of map kinase activity GO:0043406 84 0.046
cellular response to hormone stimulus GO:0032870 150 0.046
regulation of synaptic plasticity GO:0048167 87 0.046
regulation of cell projection organization GO:0031344 206 0.046
Mouse
striated muscle cell development GO:0055002 125 0.046
response to drug GO:0042493 75 0.046
positive regulation of lymphocyte differentiation GO:0045621 61 0.045
Mouse
negative regulation of phagocytosis GO:0050765 4 0.045
positive regulation of nervous system development GO:0051962 221 0.045
Mouse
regulation of interleukin 6 production GO:0032675 55 0.045
ion transmembrane transport GO:0034220 361 0.044
negative regulation of phosphorus metabolic process GO:0010563 184 0.044
Mouse
response to organic cyclic compound GO:0014070 198 0.044
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.044
Mouse
negative regulation of macrophage apoptotic process GO:2000110 3 0.044
negative regulation of b cell activation GO:0050869 27 0.044
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.044
telencephalon cell migration GO:0022029 55 0.043
stress activated mapk cascade GO:0051403 80 0.043
regulation of cell division GO:0051302 76 0.043
regulation of ion transport GO:0043269 215 0.043
Mouse
oxidation reduction process GO:0055114 342 0.043
negative regulation of leukocyte degranulation GO:0043301 7 0.043
cerebral cortex cell migration GO:0021795 44 0.043
cell cell recognition GO:0009988 44 0.043
negative regulation of intracellular signal transduction GO:1902532 167 0.042
Mouse
lung development GO:0030324 164 0.042
regulation of immunoglobulin mediated immune response GO:0002889 37 0.042
negative regulation of apoptotic signaling pathway GO:2001234 104 0.042
regulation of coagulation GO:0050818 31 0.042
Mouse
response to peptide hormone GO:0043434 127 0.042
b cell receptor signaling pathway GO:0050853 20 0.042
Human Mouse
regulation of jnk cascade GO:0046328 62 0.041
learning or memory GO:0007611 148 0.041
Fly
striated muscle tissue development GO:0014706 293 0.041
positive regulation of stress activated mapk cascade GO:0032874 48 0.041
regulation of transferase activity GO:0051338 263 0.041
Mouse Fly
stem cell maintenance GO:0019827 130 0.040
regulation of wnt signaling pathway GO:0030111 123 0.040
Mouse
protein maturation GO:0051604 176 0.040
regulation of innate immune response GO:0045088 91 0.040
Mouse
cellular defense response GO:0006968 6 0.040
modulation by symbiont of host immune response GO:0052553 1 0.040
positive regulation of intracellular transport GO:0032388 70 0.040
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.040
plasma membrane organization GO:0007009 90 0.040
regulation of reactive oxygen species metabolic process GO:2000377 40 0.039
developmental maturation GO:0021700 193 0.039
Mouse
organic acid biosynthetic process GO:0016053 86 0.039
platelet activation GO:0030168 40 0.039
Mouse
establishment of organelle localization GO:0051656 122 0.039
Worm
mitotic cell cycle GO:0000278 195 0.039
Worm
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.039
Mouse
dendritic cell differentiation GO:0097028 26 0.038
Mouse
negative regulation of lymphocyte proliferation GO:0050672 45 0.038
Mouse
ras protein signal transduction GO:0007265 77 0.038
regulation of protein transport GO:0051223 163 0.038
Mouse
leukocyte homeostasis GO:0001776 79 0.038
Mouse
response to organonitrogen compound GO:0010243 246 0.038
placenta development GO:0001890 140 0.038
positive regulation of glial cell differentiation GO:0045687 21 0.038
regulation of b cell activation GO:0050864 81 0.038
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.038
Fly
nitric oxide metabolic process GO:0046209 25 0.037
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
regulation of epithelial cell proliferation GO:0050678 141 0.037
cellular response to growth factor stimulus GO:0071363 197 0.036
Mouse
regulation of cell killing GO:0031341 40 0.036
associative learning GO:0008306 61 0.036
Fly
immunoglobulin production GO:0002377 73 0.036
regulation of cellular component size GO:0032535 121 0.036
Fly
antigen processing and presentation of peptide antigen GO:0048002 29 0.035
regulation of production of molecular mediator of immune response GO:0002700 65 0.035
interleukin 12 production GO:0032615 32 0.035
mast cell activation GO:0045576 27 0.035
Mouse
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.035
gamma delta t cell differentiation GO:0042492 11 0.035
Mouse
keratinocyte differentiation GO:0030216 48 0.034
intracellular receptor signaling pathway GO:0030522 74 0.034
Mouse
negative regulation of multi organism process GO:0043901 68 0.034
activation of mapk activity GO:0000187 59 0.033
regulation of platelet activation GO:0010543 17 0.033
Mouse
nuclear division GO:0000280 158 0.033
negative t cell selection GO:0043383 13 0.033
response to growth factor GO:0070848 198 0.033
Mouse
cell chemotaxis GO:0060326 81 0.033
response to insulin GO:0032868 100 0.033
myeloid leukocyte mediated immunity GO:0002444 42 0.033
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.033
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.032
regulation of calcium mediated signaling GO:0050848 19 0.032
meiotic cell cycle GO:0051321 122 0.032
regulation of antigen processing and presentation GO:0002577 10 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.032
Mouse
regulation of calcium ion transport GO:0051924 69 0.032
Mouse
skin development GO:0043588 220 0.032
positive regulation of calcium ion transport GO:0051928 27 0.032
leukocyte mediated cytotoxicity GO:0001909 62 0.031
negative regulation of adaptive immune response GO:0002820 25 0.031
canonical wnt signaling pathway GO:0060070 130 0.031
Mouse
growth of symbiont in host GO:0044117 23 0.031
respiratory tube development GO:0030323 167 0.031
t cell proliferation GO:0042098 120 0.031
Mouse
lymphocyte costimulation GO:0031294 15 0.031
regulation of t cell differentiation GO:0045580 83 0.031
Mouse
interspecies interaction between organisms GO:0044419 83 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
Mouse Fly
activation of phospholipase c activity GO:0007202 2 0.031
Mouse
monoamine transport GO:0015844 33 0.031
regulation of b cell mediated immunity GO:0002712 37 0.030
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.030
detection of molecule of bacterial origin GO:0032490 2 0.030
positive regulation of b cell mediated immunity GO:0002714 26 0.030
regulation of canonical wnt signaling pathway GO:0060828 82 0.030
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.030
production of molecular mediator involved in inflammatory response GO:0002532 21 0.030
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.030
neuron migration GO:0001764 122 0.029
Mouse
leukocyte chemotaxis GO:0030595 69 0.029
cation transmembrane transport GO:0098655 266 0.029
negative regulation of response to wounding GO:1903035 77 0.029
regulation of protein localization GO:0032880 231 0.029
Mouse
regulation of blood pressure GO:0008217 93 0.029
regulation of erk1 and erk2 cascade GO:0070372 71 0.029
Mouse
t helper 1 type immune response GO:0042088 25 0.029
skeletal system development GO:0001501 356 0.029
cell division GO:0051301 120 0.028
neuron projection guidance GO:0097485 141 0.028
Fly

Blk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.243
immune system disease DOID:2914 0 0.243
primary immunodeficiency disease DOID:612 0 0.076
hematopoietic system disease DOID:74 0 0.038