Mus musculus

30 known processes

Bnip3

BCL2/adenovirus E1B interacting protein 3

(Aliases: Nip3)

Bnip3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.332
cellular lipid metabolic process GO:0044255 323 0.295
oxidation reduction process GO:0055114 342 0.194
cellular amino acid metabolic process GO:0006520 103 0.146
carbohydrate metabolic process GO:0005975 230 0.127
nucleotide metabolic process GO:0009117 332 0.126
nucleobase containing small molecule metabolic process GO:0055086 352 0.121
coenzyme biosynthetic process GO:0009108 23 0.110
cellular ketone metabolic process GO:0042180 84 0.085
apoptotic signaling pathway GO:0097190 306 0.081
cofactor metabolic process GO:0051186 80 0.078
nucleoside phosphate metabolic process GO:0006753 338 0.074
lipid catabolic process GO:0016042 69 0.073
organic hydroxy compound metabolic process GO:1901615 203 0.072
cellular carbohydrate metabolic process GO:0044262 119 0.070
coenzyme metabolic process GO:0006732 52 0.069
hexose metabolic process GO:0019318 98 0.068
fat cell differentiation GO:0045444 160 0.068
cellular response to hormone stimulus GO:0032870 150 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.066
response to oxygen levels GO:0070482 62 0.064
Human
response to oxidative stress GO:0006979 123 0.061
cellular response to organonitrogen compound GO:0071417 145 0.057
carbohydrate biosynthetic process GO:0016051 74 0.056
purine containing compound metabolic process GO:0072521 311 0.056
alpha amino acid metabolic process GO:1901605 59 0.055
response to organonitrogen compound GO:0010243 246 0.054
response to extracellular stimulus GO:0009991 127 0.053
thioester biosynthetic process GO:0035384 7 0.053
glycerolipid metabolic process GO:0046486 122 0.052
fatty acid metabolic process GO:0006631 121 0.052
lipid biosynthetic process GO:0008610 179 0.051
negative regulation of protein metabolic process GO:0051248 282 0.050
glucose metabolic process GO:0006006 92 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
response to decreased oxygen levels GO:0036293 59 0.045
Human
cellular amine metabolic process GO:0044106 44 0.043
monosaccharide metabolic process GO:0005996 106 0.043
pyruvate metabolic process GO:0006090 28 0.042
organophosphate biosynthetic process GO:0090407 122 0.042
response to peptide GO:1901652 136 0.042
amine metabolic process GO:0009308 45 0.042
heterocycle catabolic process GO:0046700 280 0.040
positive regulation of apoptotic process GO:0043065 217 0.040
Human Mouse
regulation of glucose metabolic process GO:0010906 60 0.040
gluconeogenesis GO:0006094 39 0.040
peptidyl amino acid modification GO:0018193 336 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
positive regulation of programmed cell death GO:0043068 218 0.039
Human Mouse
regulation of mitochondrial fission GO:0090140 3 0.039
Human
spermatogenesis GO:0007283 284 0.039
glycogen metabolic process GO:0005977 32 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
generation of precursor metabolites and energy GO:0006091 103 0.037
hexose catabolic process GO:0019320 3 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.036
macromolecule catabolic process GO:0009057 281 0.036
Human
anion transport GO:0006820 177 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.035
energy derivation by oxidation of organic compounds GO:0015980 77 0.035
lipid homeostasis GO:0055088 63 0.034
hexose biosynthetic process GO:0019319 39 0.034
peptidyl proline hydroxylation GO:0019511 3 0.034
cellular lipid catabolic process GO:0044242 52 0.033
cellular response to peptide GO:1901653 92 0.033
transmembrane transport GO:0055085 412 0.033
organophosphate catabolic process GO:0046434 232 0.032
organic anion transport GO:0015711 137 0.032
cholesterol homeostasis GO:0042632 44 0.032
acetyl coa biosynthetic process GO:0006085 5 0.032
lipid transport GO:0006869 98 0.032
response to radiation GO:0009314 165 0.031
organic acid biosynthetic process GO:0016053 86 0.031
aromatic compound catabolic process GO:0019439 286 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
cation transport GO:0006812 399 0.030
cellular response to insulin stimulus GO:0032869 78 0.030
circadian regulation of gene expression GO:0032922 48 0.030
negative regulation of phosphorylation GO:0042326 166 0.030
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.030
response to nutrient levels GO:0031667 109 0.029
lipoprotein metabolic process GO:0042157 43 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
regulation of cell cycle GO:0051726 281 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
nucleoside metabolic process GO:0009116 246 0.029
regulation of homeostatic process GO:0032844 182 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
response to hypoxia GO:0001666 58 0.028
Human
carbohydrate catabolic process GO:0016052 32 0.028
protein catabolic process GO:0030163 221 0.028
Human
regulation of membrane potential GO:0042391 192 0.028
Human
cytokine production GO:0001816 319 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
Human
nitrogen compound transport GO:0071705 271 0.028
acylglycerol metabolic process GO:0006639 55 0.028
negative regulation of molecular function GO:0044092 258 0.027
negative regulation of protein modification process GO:0031400 163 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
Human
glucose homeostasis GO:0042593 128 0.027
cellular response to peptide hormone stimulus GO:0071375 92 0.026
regulation of carbohydrate metabolic process GO:0006109 75 0.026
response to light stimulus GO:0009416 135 0.026
sterol homeostasis GO:0055092 45 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
lipid localization GO:0010876 126 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
sulfur compound metabolic process GO:0006790 100 0.026
sulfur compound biosynthetic process GO:0044272 37 0.026
response to peptide hormone GO:0043434 127 0.026
sterol metabolic process GO:0016125 58 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
response to organic cyclic compound GO:0014070 198 0.025
regulation of response to wounding GO:1903034 189 0.025
maintenance of location GO:0051235 89 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
positive regulation of cell death GO:0010942 224 0.024
Human Mouse
male gamete generation GO:0048232 285 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
polysaccharide metabolic process GO:0005976 39 0.024
regulation of cytokine production GO:0001817 266 0.023
thioester metabolic process GO:0035383 19 0.023
protein hydroxylation GO:0018126 4 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
pyridine nucleotide biosynthetic process GO:0019363 4 0.023
small molecule biosynthetic process GO:0044283 132 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
mitochondrion organization GO:0007005 134 0.023
Human
cation homeostasis GO:0055080 212 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
purine nucleotide catabolic process GO:0006195 211 0.022
neuron death GO:0070997 154 0.022
lipid modification GO:0030258 65 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
cellular homeostasis GO:0019725 240 0.022
heart morphogenesis GO:0003007 178 0.021
regulation of hydrolase activity GO:0051336 246 0.021
monosaccharide biosynthetic process GO:0046364 44 0.021
mapk cascade GO:0000165 281 0.021
cellular response to extracellular stimulus GO:0031668 81 0.021
regulation of coenzyme metabolic process GO:0051196 4 0.021
glycerolipid biosynthetic process GO:0045017 50 0.020
gpi anchor metabolic process GO:0006505 7 0.020
nucleoside phosphate biosynthetic process GO:1901293 79 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
neutral lipid metabolic process GO:0006638 57 0.020
positive regulation of protein modification process GO:0031401 299 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
glucan metabolic process GO:0044042 32 0.020
cellular protein catabolic process GO:0044257 155 0.020
Human
homeostasis of number of cells GO:0048872 210 0.019
carbohydrate homeostasis GO:0033500 128 0.019
cell type specific apoptotic process GO:0097285 268 0.019
energy reserve metabolic process GO:0006112 39 0.019
alcohol metabolic process GO:0006066 116 0.019
microtubule based process GO:0007017 236 0.019
response to insulin GO:0032868 100 0.019
protein ubiquitination GO:0016567 171 0.019
protein processing GO:0016485 163 0.019
nucleotide catabolic process GO:0009166 217 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
Human
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
regulation of transferase activity GO:0051338 263 0.019
protein maturation GO:0051604 176 0.019
regulation of kinase activity GO:0043549 249 0.019
transmission of nerve impulse GO:0019226 76 0.019
blood circulation GO:0008015 195 0.018
pyruvate transport GO:0006848 2 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
regulation of organelle organization GO:0033043 289 0.018
Human
long chain fatty acid import GO:0044539 2 0.018
regulation of hormone levels GO:0010817 211 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
atp metabolic process GO:0046034 75 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
respiratory system development GO:0060541 190 0.018
intracellular protein transport GO:0006886 204 0.018
cellular response to oxidative stress GO:0034599 76 0.017
cholesterol metabolic process GO:0008203 56 0.017
steroid metabolic process GO:0008202 119 0.017
regulation of protein localization GO:0032880 231 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
Human
regulation of mapk cascade GO:0043408 248 0.017
cellular glucan metabolic process GO:0006073 32 0.017
brown fat cell differentiation GO:0050873 36 0.017
regulation of protein kinase activity GO:0045859 232 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
neuronal action potential GO:0019228 54 0.017
cation transmembrane transport GO:0098655 266 0.017
locomotory behavior GO:0007626 195 0.017
regulation of mitochondrion organization GO:0010821 27 0.017
Human
negative regulation of organelle organization GO:0010639 90 0.017
Human
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.017
ion transmembrane transport GO:0034220 361 0.017
synaptic transmission GO:0007268 329 0.017
circulatory system process GO:0003013 197 0.016
acyl coa metabolic process GO:0006637 19 0.016
lipid oxidation GO:0034440 29 0.016
cellular response to hypoxia GO:0071456 17 0.016
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.016
triglyceride metabolic process GO:0006641 51 0.016
cytoplasmic transport GO:0016482 234 0.016
myeloid cell differentiation GO:0030099 233 0.016
organic hydroxy compound biosynthetic process GO:1901617 77 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.016
skeletal system development GO:0001501 356 0.016
dna metabolic process GO:0006259 303 0.016
blood vessel morphogenesis GO:0048514 285 0.016
cell growth GO:0016049 130 0.016
fatty acid alpha oxidation GO:0001561 2 0.016
peptidyl serine modification GO:0018209 83 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
multicellular organismal signaling GO:0035637 91 0.015
chromatin organization GO:0006325 206 0.015
positive regulation of organelle organization GO:0010638 128 0.015
Human
organonitrogen compound biosynthetic process GO:1901566 192 0.015
small molecule catabolic process GO:0044282 71 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
response to inorganic substance GO:0010035 96 0.015
Human
regulation of cell cycle process GO:0010564 160 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
sensory perception GO:0007600 245 0.015
fatty acid oxidation GO:0019395 28 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
myeloid cell homeostasis GO:0002262 114 0.015
regulation of secretion GO:0051046 274 0.015
cellular response to nutrient levels GO:0031669 64 0.015
protein oligomerization GO:0051259 67 0.015
mitotic cell cycle process GO:1903047 159 0.015
cellular chemical homeostasis GO:0055082 215 0.015
glycogen biosynthetic process GO:0005978 14 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
rho protein signal transduction GO:0007266 32 0.014
acyl coa biosynthetic process GO:0071616 7 0.014
negative regulation of translational initiation GO:0045947 4 0.014
substantia nigra development GO:0021762 2 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
cardiac muscle tissue development GO:0048738 130 0.014
neuron apoptotic process GO:0051402 142 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of lipid biosynthetic process GO:0046890 54 0.014
tissue homeostasis GO:0001894 115 0.014
purine containing compound catabolic process GO:0072523 213 0.014
regulation of proteolysis GO:0030162 164 0.014
cholesterol transport GO:0030301 38 0.014
skeletal system morphogenesis GO:0048705 203 0.014
anatomical structure homeostasis GO:0060249 145 0.014
action potential GO:0001508 78 0.014
nicotinamide nucleotide metabolic process GO:0046496 12 0.014
organic hydroxy compound transport GO:0015850 93 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
muscle tissue development GO:0060537 308 0.013
regulation of translation GO:0006417 71 0.013
oxidoreduction coenzyme metabolic process GO:0006733 16 0.013
regulation of neuron death GO:1901214 134 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
gpi anchor biosynthetic process GO:0006506 6 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
carboxylic acid transport GO:0046942 100 0.013
regulation of anatomical structure size GO:0090066 178 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
positive regulation of kinase activity GO:0033674 155 0.013
histone modification GO:0016570 159 0.013
response to acid chemical GO:0001101 111 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
germ cell development GO:0007281 185 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
organic acid transport GO:0015849 101 0.013
connective tissue development GO:0061448 179 0.013
cognition GO:0050890 149 0.013
inflammatory response GO:0006954 244 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
meiotic cell cycle GO:0051321 122 0.012
regulation of cell activation GO:0050865 289 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
rhythmic process GO:0048511 174 0.012
translation GO:0006412 93 0.012
response to lipopolysaccharide GO:0032496 128 0.012
regulation of system process GO:0044057 200 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
protein lipidation GO:0006497 28 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
ossification GO:0001503 216 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of peptidase activity GO:0052547 96 0.012
striated muscle tissue development GO:0014706 293 0.012
immune effector process GO:0002252 321 0.012
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.012
cellular ion homeostasis GO:0006873 165 0.012
pyridine containing compound metabolic process GO:0072524 14 0.012
cellular response to external stimulus GO:0071496 88 0.012
Human
circadian rhythm GO:0007623 114 0.012
learning or memory GO:0007611 148 0.012
nuclear transport GO:0051169 139 0.012
renal system development GO:0072001 225 0.012
organelle fission GO:0048285 170 0.012
Human
cellular protein complex assembly GO:0043623 116 0.012
multi multicellular organism process GO:0044706 109 0.012
negative regulation of growth GO:0045926 99 0.012
divalent inorganic cation transport GO:0072511 178 0.012
cellular polysaccharide metabolic process GO:0044264 38 0.012
ras protein signal transduction GO:0007265 77 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of intracellular transport GO:0032386 159 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.011
muscle cell differentiation GO:0042692 261 0.011
phospholipid metabolic process GO:0006644 87 0.011
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
Human
amide transport GO:0042886 138 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
negative regulation of cell cycle GO:0045786 123 0.011
angiogenesis GO:0001525 201 0.011
nuclear division GO:0000280 158 0.011
regulation of ph GO:0006885 26 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of cellular response to stress GO:0080135 159 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
regulation of defense response GO:0031347 233 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.011
cellular response to lipid GO:0071396 145 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
skin development GO:0043588 220 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
chemotaxis GO:0006935 247 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
sterol transport GO:0015918 38 0.011
diacylglycerol biosynthetic process GO:0006651 2 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
glucan biosynthetic process GO:0009250 14 0.011
respiratory tube development GO:0030323 167 0.011
camera type eye development GO:0043010 266 0.011
response to uv GO:0009411 44 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
adult behavior GO:0030534 135 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
telencephalon development GO:0021537 186 0.010
membrane organization GO:0061024 245 0.010
Human
response to steroid hormone GO:0048545 56 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
forebrain development GO:0030900 302 0.010
regionalization GO:0003002 337 0.010
cofactor biosynthetic process GO:0051188 41 0.010
response to reactive oxygen species GO:0000302 56 0.010
cellular amide metabolic process GO:0043603 58 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
oxygen homeostasis GO:0032364 2 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
bone development GO:0060348 120 0.010
negative regulation of cytokine production GO:0001818 84 0.010
insulin receptor signaling pathway GO:0008286 49 0.010
endomembrane system organization GO:0010256 147 0.010
meiotic nuclear division GO:0007126 115 0.010
hormone secretion GO:0046879 128 0.010
positive regulation of secretion GO:0051047 130 0.010
muscle system process GO:0003012 141 0.010

Bnip3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.118
disease of metabolism DOID:0014667 0 0.118
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
carbohydrate metabolic disorder DOID:2978 0 0.016
neuromuscular disease DOID:440 0 0.014
neuropathy DOID:870 0 0.014
central nervous system disease DOID:331 0 0.013
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010
neurodegenerative disease DOID:1289 0 0.010