Mus musculus

66 known processes

Brd4

bromodomain containing 4

(Aliases: WI-11513,Brd5,MCAP,HUNK1)

Brd4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 10 0.986
chromatin organization GO:0006325 206 0.984
dna metabolic process GO:0006259 303 0.918
regulation of transcription during meiosis GO:0051037 1 0.825
Mouse
chromatin modification GO:0016568 187 0.818
cellular response to dna damage stimulus GO:0006974 207 0.798
Human
histone lysine methylation GO:0034968 50 0.736
male meiosis i GO:0007141 16 0.721
Mouse
aromatic compound catabolic process GO:0019439 286 0.634
regulation of chromosome organization GO:0033044 83 0.623
covalent chromatin modification GO:0016569 163 0.609
histone deubiquitination GO:0016578 2 0.605
mrna processing GO:0006397 63 0.603
nuclear division GO:0000280 158 0.598
Mouse
histone modification GO:0016570 159 0.565
macromolecule catabolic process GO:0009057 281 0.443
blastocyst growth GO:0001832 23 0.442
protein dna complex subunit organization GO:0071824 28 0.435
Mouse
histone methylation GO:0016571 71 0.432
methylation GO:0032259 134 0.419
regulation of cell cycle GO:0051726 281 0.416
Human
stem cell fate specification GO:0048866 3 0.405
Worm
embryonic organ morphogenesis GO:0048562 276 0.369
mrna metabolic process GO:0016071 84 0.361
dna methylation GO:0006306 43 0.361
nucleosome disassembly GO:0006337 1 0.357
protein dna complex disassembly GO:0032986 1 0.356
regulation of histone modification GO:0031056 56 0.337
purine containing compound metabolic process GO:0072521 311 0.337
regulation of organelle organization GO:0033043 289 0.336
dna repair GO:0006281 107 0.314
olfactory learning GO:0008355 2 0.311
negative regulation of protein metabolic process GO:0051248 282 0.306
male gamete generation GO:0048232 285 0.265
Mouse
spermatogenesis GO:0007283 284 0.261
Mouse
lateral inhibition GO:0046331 1 0.258
positive regulation of histone methylation GO:0031062 16 0.251
regulation of histone methylation GO:0031060 30 0.248
negative regulation of cell cycle GO:0045786 123 0.243
Human
regulation of chromatin modification GO:1903308 57 0.236
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.229
Human
ribonucleotide metabolic process GO:0009259 291 0.227
stem cell differentiation GO:0048863 268 0.218
Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.207
endocytosis GO:0006897 168 0.205
peptidyl lysine modification GO:0018205 77 0.204
chromatin remodeling GO:0006338 32 0.203
Human Mouse
protein methylation GO:0006479 81 0.203
regulation of cell cycle process GO:0010564 160 0.200
Human
histone h4 k12 acetylation GO:0043983 2 0.200
nucleoside phosphate metabolic process GO:0006753 338 0.195
nucleoside metabolic process GO:0009116 246 0.195
habituation GO:0046959 3 0.188
axonogenesis GO:0007409 274 0.186
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.186
macromolecule methylation GO:0043414 120 0.185
organic cyclic compound catabolic process GO:1901361 295 0.183
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.178
cellular macromolecule catabolic process GO:0044265 206 0.176
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.173
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.170
digestive system development GO:0055123 200 0.169
germ cell development GO:0007281 185 0.168
organelle fission GO:0048285 170 0.164
Mouse
lipid localization GO:0010876 126 0.161
cellular nitrogen compound catabolic process GO:0044270 280 0.155
posttranscriptional gene silencing GO:0016441 10 0.148
maintenance of chromatin silencing GO:0006344 2 0.146
regulation of cellular response to stress GO:0080135 159 0.145
Human
negative regulation of cell cycle process GO:0010948 69 0.143
Human
ribose phosphate metabolic process GO:0019693 291 0.142
purine containing compound catabolic process GO:0072523 213 0.140
mitotic cell cycle process GO:1903047 159 0.138
Human
chromatin assembly or disassembly GO:0006333 16 0.137
compound eye development GO:0048749 1 0.136
purine nucleotide catabolic process GO:0006195 211 0.135
segmentation GO:0035282 93 0.131
Fly
cellular amino acid metabolic process GO:0006520 103 0.126
internal peptidyl lysine acetylation GO:0018393 42 0.124
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.124
negative regulation of cellular protein metabolic process GO:0032269 247 0.123
nucleotide metabolic process GO:0009117 332 0.122
leukocyte differentiation GO:0002521 342 0.121
protein alkylation GO:0008213 81 0.117
positive regulation of dna templated transcription elongation GO:0032786 2 0.115
Human
histone h4 acetylation GO:0043967 10 0.111
immune effector process GO:0002252 321 0.110
negative regulation of intracellular signal transduction GO:1902532 167 0.110
dna alkylation GO:0006305 43 0.107
nucleotide catabolic process GO:0009166 217 0.103
hypermethylation of cpg island GO:0044027 3 0.103
nucleoside monophosphate metabolic process GO:0009123 85 0.101
histone h3 k4 methylation GO:0051568 23 0.099
regulation of mrna processing GO:0050684 41 0.097
purine ribonucleotide metabolic process GO:0009150 290 0.097
dna methylation involved in gamete generation GO:0043046 15 0.096
maintenance of location GO:0051235 89 0.095
negative regulation of protein modification process GO:0031400 163 0.095
glycosyl compound metabolic process GO:1901657 246 0.094
nucleobase containing small molecule metabolic process GO:0055086 352 0.094
neuron projection guidance GO:0097485 141 0.094
meiosis i GO:0007127 60 0.093
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.093
Human
chromatin disassembly GO:0031498 1 0.092
canonical wnt signaling pathway GO:0060070 130 0.091
blastocyst development GO:0001824 80 0.091
purine ribonucleoside metabolic process GO:0046128 241 0.090
ribonucleoside metabolic process GO:0009119 245 0.088
peptidyl amino acid modification GO:0018193 336 0.088
chromatin silencing GO:0006342 15 0.088
regulation of cellular ketone metabolic process GO:0010565 66 0.087
purine nucleoside triphosphate catabolic process GO:0009146 203 0.087
atp metabolic process GO:0046034 75 0.085
positive regulation of histone h3 k9 methylation GO:0051574 4 0.085
gonad development GO:0008406 141 0.085
amine metabolic process GO:0009308 45 0.083
histone acetylation GO:0016573 41 0.082
stem cell maintenance GO:0019827 130 0.082
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.082
Human
rhythmic process GO:0048511 174 0.081
negative regulation of phosphorus metabolic process GO:0010563 184 0.081
nucleoside phosphate catabolic process GO:1901292 222 0.080
multicellular organism growth GO:0035264 161 0.079
cell cycle checkpoint GO:0000075 47 0.078
Human
regulation of cellular catabolic process GO:0031329 242 0.078
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.078
n terminal protein amino acid modification GO:0031365 6 0.077
dna modification GO:0006304 50 0.077
sensory organ morphogenesis GO:0090596 242 0.075
mitotic cell cycle GO:0000278 195 0.074
Human
histone h3 k14 acetylation GO:0044154 3 0.074
purine ribonucleotide catabolic process GO:0009154 208 0.074
purine nucleoside metabolic process GO:0042278 241 0.073
gene silencing by rna GO:0031047 19 0.073
ribonucleoside monophosphate catabolic process GO:0009158 57 0.073
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.072
chromatin assembly GO:0031497 13 0.072
myeloid cell differentiation GO:0030099 233 0.070
negative regulation of gene expression epigenetic GO:0045814 15 0.070
rna catabolic process GO:0006401 29 0.070
heterocycle catabolic process GO:0046700 280 0.069
cognition GO:0050890 149 0.069
positive regulation of chromosome organization GO:2001252 33 0.069
learning or memory GO:0007611 148 0.068
rna processing GO:0006396 105 0.067
Mouse
oogenesis GO:0048477 56 0.067
ribonucleoside triphosphate catabolic process GO:0009203 199 0.066
generation of precursor metabolites and energy GO:0006091 103 0.065
wnt signaling pathway GO:0016055 188 0.065
muscle tissue development GO:0060537 308 0.065
negative regulation of mitotic cell cycle GO:0045930 58 0.064
protein catabolic process GO:0030163 221 0.064
striated muscle tissue development GO:0014706 293 0.063
purine ribonucleoside catabolic process GO:0046130 205 0.062
cellular protein catabolic process GO:0044257 155 0.062
regulation of chromatin organization GO:1902275 57 0.061
cellular ketone metabolic process GO:0042180 84 0.060
receptor mediated endocytosis GO:0006898 51 0.059
pole plasm assembly GO:0007315 2 0.059
positive regulation of histone modification GO:0031058 28 0.059
circadian rhythm GO:0007623 114 0.059
body morphogenesis GO:0010171 45 0.059
development of primary sexual characteristics GO:0045137 143 0.058
cell cell signaling involved in cell fate commitment GO:0045168 35 0.058
negative regulation of cell cycle phase transition GO:1901988 48 0.058
proteasomal protein catabolic process GO:0010498 98 0.058
gene silencing GO:0016458 38 0.057
leukocyte mediated immunity GO:0002443 174 0.057
modification dependent macromolecule catabolic process GO:0043632 133 0.057
positive regulation of notch signaling pathway GO:0045747 18 0.056
placenta development GO:0001890 140 0.056
positive regulation of organelle organization GO:0010638 128 0.056
chemotaxis GO:0006935 247 0.056
peptidyl lysine acetylation GO:0018394 45 0.056
oxidation reduction process GO:0055114 342 0.056
cardiac muscle cell differentiation GO:0055007 69 0.055
regulation of rna splicing GO:0043484 37 0.055
Mouse
histone h3 k9 methylation GO:0051567 17 0.055
cartilage development GO:0051216 140 0.054
regulation of mitotic cell cycle phase transition GO:1901990 73 0.054
Human
positive regulation of mrna 3 end processing GO:0031442 5 0.054
regulation of mrna 3 end processing GO:0031440 6 0.054
nucleosome positioning GO:0016584 4 0.053
regulation of wnt signaling pathway GO:0030111 123 0.053
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 2 0.053
purine nucleotide metabolic process GO:0006163 302 0.053
protein modification by small protein conjugation or removal GO:0070647 207 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.052
ribonucleotide catabolic process GO:0009261 208 0.051
heart morphogenesis GO:0003007 178 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
regulation of nuclear division GO:0051783 56 0.050
female gamete generation GO:0007292 74 0.049
skeletal system development GO:0001501 356 0.049
intracellular mrna localization GO:0008298 4 0.049
asymmetric stem cell division GO:0098722 3 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.049
epithalamus development GO:0021538 2 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.049
embryonic placenta development GO:0001892 98 0.049
negative regulation of molecular function GO:0044092 258 0.048
peptidyl lysine methylation GO:0018022 29 0.047
phagocytosis GO:0006909 66 0.047
meiotic cell cycle GO:0051321 122 0.047
Mouse
germ line stem cell division GO:0042078 2 0.046
mitotic cytokinesis GO:0000281 4 0.046
lipid biosynthetic process GO:0008610 179 0.046
regionalization GO:0003002 337 0.045
Fly
positive regulation of growth GO:0045927 104 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
regulation of histone h3 k9 methylation GO:0051570 8 0.045
mrna catabolic process GO:0006402 22 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.045
regulation of histone h3 k4 methylation GO:0051569 12 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
posttranscriptional regulation of gene expression GO:0010608 155 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.044
positive regulation of mrna metabolic process GO:1903313 17 0.044
organism emergence from protective structure GO:0071684 4 0.044
negative regulation of gene silencing GO:0060969 2 0.044
purine nucleoside catabolic process GO:0006152 205 0.044
meiotic nuclear division GO:0007126 115 0.043
Mouse
protein modification by small protein conjugation GO:0032446 187 0.043
transcription from rna polymerase iii promoter GO:0006383 3 0.043
purine nucleoside monophosphate metabolic process GO:0009126 81 0.042
skeletal system morphogenesis GO:0048705 203 0.042
rna splicing GO:0008380 54 0.042
Mouse
chromatin silencing at rdna GO:0000183 3 0.042
negative regulation of cell proliferation GO:0008285 296 0.042
regulation of chromatin silencing GO:0031935 2 0.042
somitogenesis GO:0001756 69 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.041
memory GO:0007613 58 0.040
nucleoside catabolic process GO:0009164 206 0.040
atp dependent chromatin remodeling GO:0043044 9 0.040
internal protein amino acid acetylation GO:0006475 42 0.040
regulation of organ growth GO:0046620 61 0.040
protein modification by small protein removal GO:0070646 21 0.039
cell division GO:0051301 120 0.039
locomotory behavior GO:0007626 195 0.038
erythrocyte differentiation GO:0030218 88 0.038
ribonucleoside monophosphate metabolic process GO:0009161 80 0.038
regulation of hormone levels GO:0010817 211 0.038
regulation of lymphocyte activation GO:0051249 240 0.038
organ growth GO:0035265 117 0.038
organonitrogen compound catabolic process GO:1901565 264 0.037
negative regulation of protein maturation GO:1903318 79 0.037
gland development GO:0048732 330 0.037
nuclear transcribed mrna catabolic process GO:0000956 16 0.037
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.036
regulation of fat cell differentiation GO:0045598 81 0.036
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.036
pre mirna processing GO:0031054 3 0.036
positive regulation of binding GO:0051099 49 0.036
digestive tract development GO:0048565 190 0.036
myeloid cell homeostasis GO:0002262 114 0.036
modification dependent protein catabolic process GO:0019941 133 0.036
male meiosis GO:0007140 37 0.035
Mouse
oocyte differentiation GO:0009994 35 0.035
regulation of kinase activity GO:0043549 249 0.035
lung epithelium development GO:0060428 37 0.035
atp catabolic process GO:0006200 55 0.035
rho protein signal transduction GO:0007266 32 0.035
locomotor rhythm GO:0045475 8 0.035
neuromuscular process GO:0050905 99 0.034
cardiac chamber morphogenesis GO:0003206 93 0.034
organelle assembly GO:0070925 177 0.034
histone h3 acetylation GO:0043966 14 0.034
response to organic cyclic compound GO:0014070 198 0.033
positive regulation of mrna processing GO:0050685 16 0.033
negative regulation of secretion GO:0051048 61 0.033
regulation of meiotic cell cycle GO:0051445 34 0.033
genitalia development GO:0048806 37 0.033
ribonucleoside catabolic process GO:0042454 206 0.033
oocyte construction GO:0007308 2 0.033
positive regulation of cellular catabolic process GO:0031331 148 0.033
regulation of adaptive immune response GO:0002819 90 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
neural precursor cell proliferation GO:0061351 121 0.032
cellular amine metabolic process GO:0044106 44 0.032
response to sterol GO:0036314 4 0.032
protein acylation GO:0043543 64 0.032
intracellular receptor signaling pathway GO:0030522 74 0.032
peptidyl lysine trimethylation GO:0018023 12 0.032
embryonic skeletal system development GO:0048706 120 0.032
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.032
protein autophosphorylation GO:0046777 61 0.032
regulation of leukocyte mediated immunity GO:0002703 104 0.032
bone development GO:0060348 120 0.031
regulation of cell cycle phase transition GO:1901987 77 0.031
Human
alpha beta t cell differentiation GO:0046632 69 0.031
negative regulation of mapk cascade GO:0043409 65 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
cellular lipid metabolic process GO:0044255 323 0.031
rna interference GO:0016246 2 0.030
lung development GO:0030324 164 0.030
regulation of clathrin mediated endocytosis GO:2000369 4 0.030
myeloid leukocyte differentiation GO:0002573 119 0.030
germ cell migration GO:0008354 8 0.030
thick ascending limb development GO:0072023 2 0.030
carbohydrate metabolic process GO:0005975 230 0.030
rna splicing via transesterification reactions GO:0000375 43 0.029
associative learning GO:0008306 61 0.029
viral gene expression GO:0019080 3 0.029
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.029
regulation of transferase activity GO:0051338 263 0.029
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.029
purine nucleotide biosynthetic process GO:0006164 65 0.029
limb morphogenesis GO:0035108 149 0.029
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.028
actin cytoskeleton organization GO:0030036 220 0.028
stem cell development GO:0048864 219 0.028
glial cell differentiation GO:0010001 131 0.028
regulation of protein kinase activity GO:0045859 232 0.028
transforming growth factor beta2 production GO:0032906 2 0.028
regulation of bmp signaling pathway GO:0030510 60 0.028
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.028
organelle localization GO:0051640 179 0.028
respiratory tube development GO:0030323 167 0.027
regulation of cell motility GO:2000145 236 0.027
cell adhesion GO:0007155 329 0.027
cardiocyte differentiation GO:0035051 87 0.027
cell activation involved in immune response GO:0002263 126 0.027
b cell activation GO:0042113 161 0.027
alpha beta t cell activation GO:0046631 91 0.026
cytoplasmic transport GO:0016482 234 0.026
stress activated mapk cascade GO:0051403 80 0.026
positive regulation of transferase activity GO:0051347 167 0.026
regulation of b cell activation GO:0050864 81 0.026
regulation of mapk cascade GO:0043408 248 0.026
cell fate commitment GO:0045165 210 0.026
Worm
lymphocyte proliferation GO:0046651 164 0.026
learning GO:0007612 98 0.026
habenula development GO:0021986 2 0.026
t cell differentiation GO:0030217 174 0.026
septum primum development GO:0003284 4 0.025
production of sirna involved in rna interference GO:0030422 1 0.025
anatomical structure homeostasis GO:0060249 145 0.025
regulation of cell division GO:0051302 76 0.025
negative regulation of chromatin silencing GO:0031936 1 0.025
dna hypermethylation GO:0044026 3 0.025
trna wobble uridine modification GO:0002098 2 0.025
negative regulation of bmp signaling pathway GO:0030514 35 0.025
lipid storage GO:0019915 36 0.025
negative regulation of growth GO:0045926 99 0.025
embryonic appendage morphogenesis GO:0035113 126 0.024
regulation of intracellular transport GO:0032386 159 0.024
response to retinoic acid GO:0032526 56 0.024
regulation of mrna catabolic process GO:0061013 6 0.024
positive regulation of cell death GO:0010942 224 0.024
purine nucleoside monophosphate catabolic process GO:0009128 58 0.024
oocyte axis specification GO:0007309 2 0.023
regulation of transcription by chromatin organization GO:0034401 0 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.023
ear morphogenesis GO:0042471 118 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
sister chromatid segregation GO:0000819 20 0.023
rna 3 end processing GO:0031123 20 0.023
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.023
purine ribonucleotide biosynthetic process GO:0009152 59 0.023
embryonic limb morphogenesis GO:0030326 126 0.023
fat cell differentiation GO:0045444 160 0.023
regulation of binding GO:0051098 111 0.022
organophosphate catabolic process GO:0046434 232 0.022
regulation of system process GO:0044057 200 0.022
negative regulation of organelle organization GO:0010639 90 0.022
heart trabecula morphogenesis GO:0061384 26 0.022
inner ear morphogenesis GO:0042472 101 0.022
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
meiotic cell cycle process GO:1903046 77 0.022
Mouse
adult behavior GO:0030534 135 0.022
regulation of protein localization GO:0032880 231 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
neural tube development GO:0021915 160 0.022
ribonucleoprotein complex subunit organization GO:0071826 28 0.022
cardiac muscle tissue development GO:0048738 130 0.022
erbb signaling pathway GO:0038127 32 0.021
cell growth involved in cardiac muscle cell development GO:0061049 3 0.021
forebrain development GO:0030900 302 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
spermatid differentiation GO:0048515 115 0.021
lung cell differentiation GO:0060479 30 0.021
schwann cell proliferation GO:0014010 2 0.021
t cell proliferation GO:0042098 120 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
regulation of neurological system process GO:0031644 22 0.020
male germ line stem cell asymmetric division GO:0048133 2 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
nitrogen compound transport GO:0071705 271 0.020
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
gastrulation GO:0007369 116 0.020
interspecies interaction between organisms GO:0044419 83 0.020
regulation of mrna metabolic process GO:1903311 43 0.020
negative regulation of wnt signaling pathway GO:0030178 73 0.020
positive regulation of mrna catabolic process GO:0061014 5 0.020
oocyte anterior posterior axis specification GO:0007314 2 0.020
skeletal muscle cell differentiation GO:0035914 66 0.020
exocytosis GO:0006887 121 0.020
negative regulation of kinase activity GO:0033673 81 0.020
actin filament based movement GO:0030048 23 0.020
response to oxidative stress GO:0006979 123 0.020
response to acid chemical GO:0001101 111 0.020
camera type eye development GO:0043010 266 0.020
regulation of canonical wnt signaling pathway GO:0060828 82 0.020
digestive tract morphogenesis GO:0048546 147 0.020
anion transport GO:0006820 177 0.020
neuroblast fate determination GO:0007400 1 0.019
actin cytoskeleton reorganization GO:0031532 21 0.019
trna wobble base modification GO:0002097 2 0.019
cardiac chamber development GO:0003205 108 0.019
synaptic transmission GO:0007268 329 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
synapse organization GO:0050808 125 0.019
cellular response to acid chemical GO:0071229 68 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
innate immune response GO:0045087 157 0.019
regulation of microvillus organization GO:0032530 3 0.019
sensory perception of sound GO:0007605 97 0.019
histone h4 k16 acetylation GO:0043984 3 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
cohesin localization to chromatin GO:0071921 1 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
regulation of circadian rhythm GO:0042752 58 0.019
immunoglobulin mediated immune response GO:0016064 69 0.018
circadian regulation of gene expression GO:0032922 48 0.018
midgut development GO:0007494 4 0.018
positive regulation of gene silencing by mirna GO:2000637 1 0.018
sequestering of metal ion GO:0051238 19 0.018
regulation of transforming growth factor beta2 production GO:0032909 2 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
epithelial to mesenchymal transition GO:0001837 47 0.018
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.018
posttranscriptional gene silencing by rna GO:0035194 10 0.018
molting cycle GO:0042303 90 0.018
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.018
negative regulation of mrna processing GO:0050686 12 0.018
homeostasis of number of cells GO:0048872 210 0.018
mrna 3 end processing GO:0031124 16 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
response to transforming growth factor beta GO:0071559 88 0.018
ear development GO:0043583 200 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
physiological cardiac muscle hypertrophy GO:0003301 3 0.018
negative regulation of defense response GO:0031348 77 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.017
somite development GO:0061053 81 0.017
positive regulation of chromatin modification GO:1903310 28 0.017
regulation of anatomical structure size GO:0090066 178 0.017
dna dependent dna replication GO:0006261 24 0.017
regulation of protein catabolic process GO:0042176 108 0.017
regulation of rho protein signal transduction GO:0035023 71 0.017
regulation of schwann cell proliferation GO:0010624 2 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
mitotic cell cycle checkpoint GO:0007093 31 0.017
histone h4 k20 methylation GO:0034770 8 0.017
transcription from rna polymerase i promoter GO:0006360 13 0.017
neuroblast differentiation GO:0014016 2 0.017
Worm
regulation of response to dna damage stimulus GO:2001020 34 0.017
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.017
mrna splicing via spliceosome GO:0000398 43 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.016
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.016
embryonic camera type eye development GO:0031076 36 0.016
metanephric distal convoluted tubule development GO:0072221 5 0.016
positive regulation of glycolytic process GO:0045821 4 0.016
cell recognition GO:0008037 83 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
positive regulation of wnt signaling pathway GO:0030177 45 0.016
regulation of peptidyl lysine acetylation GO:2000756 22 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.016
ossification GO:0001503 216 0.016
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.016
cellular homeostasis GO:0019725 240 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
epithelial tube formation GO:0072175 130 0.016
neural tube closure GO:0001843 90 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.016
mrna transcription GO:0009299 4 0.016
regulation of protein processing GO:0070613 96 0.016
protein ubiquitination GO:0016567 171 0.016
positive regulation of protein binding GO:0032092 29 0.016

Brd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.097
nervous system disease DOID:863 0 0.097
immune system cancer DOID:0060083 0 0.020
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
neuropathy DOID:870 0 0.019