|
|
b cell activation
|
GO:0042113 |
161 |
0.999
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.992
|
Mouse |
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.991
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.988
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.985
|
Mouse |
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.975
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.973
|
Mouse Rat |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.972
|
Mouse |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.961
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.935
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.934
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.928
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.925
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.916
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.905
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.904
|
Mouse |
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.903
|
|
|
|
negative regulation of zinc ion transmembrane transport
|
GO:0071583 |
2 |
0.902
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.897
|
Mouse Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.875
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.872
|
Mouse |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.855
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.853
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.849
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.843
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.843
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.842
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.839
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.839
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.835
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.828
|
Mouse |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.826
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.823
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.821
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.819
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.818
|
Mouse |
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
8 |
0.802
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.796
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.776
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.774
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.769
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.769
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.766
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.760
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.758
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.758
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.743
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.740
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.738
|
Mouse |
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.737
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.722
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.721
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.718
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.709
|
Mouse |
|
|
bone resorption
|
GO:0045453 |
38 |
0.708
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.700
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.692
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.683
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.681
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.680
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.677
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.674
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.671
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.651
|
Mouse |
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.650
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.640
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.617
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.604
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.596
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.595
|
Mouse Rat |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.593
|
Mouse |
|
|
lymph node development
|
GO:0048535 |
18 |
0.577
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.574
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.563
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.556
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.553
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.548
|
Mouse |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.548
|
Mouse |
|
|
icosanoid transport
|
GO:0071715 |
14 |
0.546
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.544
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.539
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.538
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.533
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.532
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.531
|
Mouse |
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.527
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.527
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.524
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.522
|
Mouse |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.522
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.517
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.515
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.509
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.507
|
Mouse |
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.507
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.498
|
Mouse |
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.491
|
Mouse |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.489
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.488
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.486
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.484
|
Mouse |
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.483
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.474
|
Mouse |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.465
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.461
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.458
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.453
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.452
|
Mouse Rat |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.451
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.451
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.447
|
Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.446
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.446
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.445
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.441
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.440
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.436
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.432
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.429
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.429
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.427
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.425
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.421
|
Mouse |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.420
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.416
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.411
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.406
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.397
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.394
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.393
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.387
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.387
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.383
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.383
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.382
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.376
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.373
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.372
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.369
|
Mouse |
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.364
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.360
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.359
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.354
|
Mouse |
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.353
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.353
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.351
|
|
|
|
phosphatidylinositol biosynthetic process
|
GO:0006661 |
15 |
0.347
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.346
|
Mouse Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.342
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.341
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.339
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.337
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.336
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.335
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.335
|
Mouse |
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.332
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.327
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.323
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.322
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.322
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.321
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.321
|
Mouse |
|
|
mast cell activation
|
GO:0045576 |
27 |
0.319
|
Mouse Rat |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.319
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.315
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.309
|
Mouse |
|
|
regulation of zinc ion transport
|
GO:0071579 |
2 |
0.307
|
|
|
|
negative regulation of interleukin 13 secretion
|
GO:2000666 |
1 |
0.306
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.306
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.305
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.305
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.301
|
Mouse |
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.301
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.299
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.297
|
Mouse |
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.293
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.293
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.290
|
Mouse |
|
|
negative regulation of zinc ion transport
|
GO:0071582 |
2 |
0.289
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.287
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.284
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.284
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.283
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.282
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.278
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.277
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.271
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.269
|
Mouse |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.269
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.268
|
Mouse |
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.261
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.259
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.259
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.258
|
|
|
|
regulation of zinc ion transmembrane transport
|
GO:0071580 |
2 |
0.257
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.255
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.254
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.245
|
Mouse |
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.245
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.240
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.238
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.238
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.237
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.235
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.234
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.234
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.231
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.230
|
Mouse |
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.229
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.228
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.225
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.224
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.221
|
Fly |
|
|
negative regulation of odontogenesis
|
GO:0042483 |
3 |
0.220
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.219
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.219
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.218
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.218
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.217
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.216
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.214
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.213
|
Mouse |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.213
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.211
|
Mouse |
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
6 |
0.211
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.210
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.207
|
Mouse |
|
|
transition metal ion transport
|
GO:0000041 |
38 |
0.203
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.203
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.202
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.201
|
Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.201
|
Mouse |
|
|
dna alkylation
|
GO:0006305 |
43 |
0.199
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.198
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.197
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.190
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.190
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.188
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.187
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.187
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.186
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.183
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.183
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.183
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.182
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.182
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.181
|
Mouse Fly |
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.181
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.181
|
Mouse |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.181
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.179
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
16 |
0.178
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
8 |
0.177
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.176
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.175
|
Mouse |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.174
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.173
|
Mouse |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.172
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.171
|
Mouse |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.170
|
Mouse |
|
|
dendrite development
|
GO:0016358 |
115 |
0.170
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.170
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.169
|
Mouse |
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.169
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.169
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.169
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.169
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.169
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
7 |
0.168
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.167
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.167
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.165
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.162
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.161
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.160
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.160
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.159
|
Rat |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.159
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.157
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.157
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.157
|
Mouse |
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.156
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.156
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.156
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.156
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.156
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.155
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.154
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.152
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.151
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.151
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.151
|
Mouse |
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.150
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.150
|
|
|
|
negative regulation of interleukin 13 production
|
GO:0032696 |
2 |
0.147
|
|
|
|
zinc ion transport
|
GO:0006829 |
12 |
0.147
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.146
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.146
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.145
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.144
|
Mouse |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.144
|
Fly |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.143
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.143
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.141
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.140
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.140
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.139
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.139
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.139
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.138
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.138
|
Mouse Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.137
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.136
|
Mouse |
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.136
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.135
|
Mouse |
|
|
acid secretion
|
GO:0046717 |
33 |
0.135
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.133
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.132
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.132
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.132
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.132
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.130
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.130
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.130
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.129
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.128
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.128
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.127
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.127
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.127
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.126
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.124
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.124
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.124
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.123
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.123
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.122
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.122
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.122
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.121
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.121
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.121
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.121
|
Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.119
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.119
|
Mouse |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.119
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.118
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.116
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.115
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.114
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.114
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.113
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.111
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.111
|
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.111
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.111
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.110
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.110
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.108
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.108
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.108
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.107
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.107
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.107
|
|
|
|
dna hypomethylation
|
GO:0044028 |
1 |
0.107
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.107
|
|
|
|
circadian temperature homeostasis
|
GO:0060086 |
2 |
0.107
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.107
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.106
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.105
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.104
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.103
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.103
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070428 |
3 |
0.102
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.102
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.102
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.101
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.101
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.101
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.100
|
Mouse |
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.100
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.100
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.100
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
26 |
0.100
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.100
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.099
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.098
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.098
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.098
|
Fly |
|
|
organic acid transport
|
GO:0015849 |
101 |
0.097
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.097
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.097
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.097
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.097
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.097
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.097
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.096
|
Mouse |
|
|
anion transport
|
GO:0006820 |
177 |
0.096
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.096
|
Mouse Rat |
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.095
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.095
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.094
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.094
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.093
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.093
|
Mouse Rat |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.093
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.093
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.093
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.093
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.093
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.092
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.092
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.092
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.092
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.091
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.091
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.090
|
Fly |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.090
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.089
|
|
|
|
regulation of interleukin 17 production
|
GO:0032660 |
8 |
0.089
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.089
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.088
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.087
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.087
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.086
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.086
|
Mouse |
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.086
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.085
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.084
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.084
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.084
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.084
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.083
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.083
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.083
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.082
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.081
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.081
|
|
|
|
negative regulation of odontogenesis of dentin containing tooth
|
GO:0042489 |
1 |
0.080
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.080
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.080
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.080
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.079
|
Mouse |
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.079
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.079
|
Mouse |
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.078
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.078
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
2 |
0.077
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.077
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.077
|
|
|
|
hypomethylation of cpg island
|
GO:0044029 |
1 |
0.077
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.077
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.076
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.076
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.076
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.076
|
|
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.075
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.075
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.075
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.075
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.075
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.075
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.074
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.074
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.073
|
Mouse |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.073
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.073
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.073
|
Mouse |
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.072
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.071
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.071
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.070
|
Rat |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.070
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.070
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.070
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.069
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.069
|
Mouse Rat |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.069
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.068
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.068
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.068
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.068
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.067
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.067
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.066
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.066
|
Mouse Fly |
