Mus musculus

0 known processes

C2

complement component 2 (within H-2S)

C2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein activation cascade GO:0072376 19 0.717
innate immune response GO:0045087 157 0.429
activation of immune response GO:0002253 138 0.382
complement activation GO:0006956 16 0.287
sterol metabolic process GO:0016125 58 0.214
immune effector process GO:0002252 321 0.209
protein maturation GO:0051604 176 0.195
regulation of defense response GO:0031347 233 0.176
regulation of endopeptidase activity GO:0052548 89 0.152
positive regulation of defense response GO:0031349 124 0.151
negative regulation of proteolysis GO:0045861 74 0.144
alcohol metabolic process GO:0006066 116 0.142
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.128
regulation of protein maturation GO:1903317 96 0.125
cellular response to cytokine stimulus GO:0071345 189 0.122
regulation of angiogenesis GO:0045765 81 0.118
regulation of peptidase activity GO:0052547 96 0.112
negative regulation of endopeptidase activity GO:0010951 44 0.107
regulation of proteolysis GO:0030162 164 0.104
lymphocyte mediated immunity GO:0002449 139 0.104
response to molecule of bacterial origin GO:0002237 143 0.104
protein processing GO:0016485 163 0.103
negative regulation of hydrolase activity GO:0051346 71 0.101
complement activation lectin pathway GO:0001867 5 0.101
cytokine production GO:0001816 319 0.099
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.089
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.085
negative regulation of protein metabolic process GO:0051248 282 0.084
negative regulation of protein maturation GO:1903318 79 0.083
negative regulation of molecular function GO:0044092 258 0.083
interspecies interaction between organisms GO:0044419 83 0.082
regulation of protein processing GO:0070613 96 0.079
angiogenesis GO:0001525 201 0.078
cholesterol metabolic process GO:0008203 56 0.075
protein kinase b signaling GO:0043491 74 0.073
positive regulation of activation of membrane attack complex GO:0001970 2 0.072
reactive nitrogen species metabolic process GO:2001057 0 0.069
b cell chemotaxis GO:0035754 3 0.067
regulation of cytokine production GO:0001817 266 0.066
phagocytosis GO:0006909 66 0.066
positive regulation of cytokine production GO:0001819 174 0.063
cell adhesion GO:0007155 329 0.061
negative regulation of gluconeogenesis GO:0045721 9 0.061
regulation of hormone levels GO:0010817 211 0.061
negative regulation of protein processing GO:0010955 79 0.061
regulation of hydrolase activity GO:0051336 246 0.060
positive regulation of protein kinase activity GO:0045860 144 0.059
regulation of complement activation GO:0030449 7 0.058
regulation of lipid metabolic process GO:0019216 118 0.057
regulation of vasculature development GO:1901342 88 0.056
negative regulation of cell proliferation GO:0008285 296 0.055
regulation of secretion GO:0051046 274 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.051
male gamete generation GO:0048232 285 0.051
response to organonitrogen compound GO:0010243 246 0.051
oxidation reduction process GO:0055114 342 0.050
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.050
response to organic cyclic compound GO:0014070 198 0.050
regulation of carbohydrate biosynthetic process GO:0043255 40 0.049
leukocyte mediated cytotoxicity GO:0001909 62 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
regulation of glucose metabolic process GO:0010906 60 0.048
glycoprotein biosynthetic process GO:0009101 89 0.048
carbohydrate metabolic process GO:0005975 230 0.048
fatty acid metabolic process GO:0006631 121 0.047
protein glycosylation GO:0006486 55 0.047
cellular ketone metabolic process GO:0042180 84 0.046
carbohydrate biosynthetic process GO:0016051 74 0.046
cellular response to interferon gamma GO:0071346 25 0.046
response to lipopolysaccharide GO:0032496 128 0.045
response to interferon gamma GO:0034341 34 0.045
negative regulation of lipid metabolic process GO:0045833 30 0.044
regulation of lymphocyte activation GO:0051249 240 0.044
activation of membrane attack complex GO:0001905 4 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.044
glycerolipid metabolic process GO:0046486 122 0.044
cation homeostasis GO:0055080 212 0.043
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.043
homeostasis of number of cells GO:0048872 210 0.043
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.043
regulation of protein kinase b signaling GO:0051896 56 0.043
lipid biosynthetic process GO:0008610 179 0.043
disruption by host of symbiont cells GO:0051852 11 0.042
monosaccharide biosynthetic process GO:0046364 44 0.042
positive regulation of angiogenesis GO:0045766 46 0.042
spermatogenesis GO:0007283 284 0.042
regulation of cellular component biogenesis GO:0044087 181 0.042
positive regulation of programmed cell death GO:0043068 218 0.042
regulation of cholesterol metabolic process GO:0090181 14 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
killing by host of symbiont cells GO:0051873 11 0.041
leukocyte mediated immunity GO:0002443 174 0.041
hemostasis GO:0007599 78 0.041
hexose biosynthetic process GO:0019319 39 0.041
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.040
regulation of cell killing GO:0031341 40 0.040
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.040
epithelial cell proliferation GO:0050673 174 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.039
regulation of acute inflammatory response GO:0002673 27 0.039
positive regulation of secretion GO:0051047 130 0.039
negative regulation of peptidase activity GO:0010466 46 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.038
endocytosis GO:0006897 168 0.038
regulation of epithelial cell proliferation GO:0050678 141 0.037
cellular lipid metabolic process GO:0044255 323 0.037
inflammatory response GO:0006954 244 0.036
regulation of cell activation GO:0050865 289 0.036
regulation of adaptive immune response GO:0002819 90 0.036
cellular homeostasis GO:0019725 240 0.036
glucose metabolic process GO:0006006 92 0.035
cellular response to molecule of bacterial origin GO:0071219 83 0.035
positive regulation of protein kinase b signaling GO:0051897 32 0.035
blood circulation GO:0008015 195 0.035
regulation of angiotensin levels in blood GO:0002002 4 0.035
gluconeogenesis GO:0006094 39 0.035
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.035
monosaccharide metabolic process GO:0005996 106 0.034
regulation of angiotensin metabolic process GO:0060177 4 0.034
single organism cell adhesion GO:0098602 156 0.034
glycoprotein metabolic process GO:0009100 116 0.034
hexose metabolic process GO:0019318 98 0.034
antigen processing and presentation GO:0019882 47 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
cytokine secretion GO:0050663 72 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
neutral lipid metabolic process GO:0006638 57 0.033
regulation of glucose transport GO:0010827 32 0.033
macromolecule glycosylation GO:0043413 55 0.033
water soluble vitamin metabolic process GO:0006767 10 0.032
endocrine process GO:0050886 39 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.032
regulation of protein kinase c activity GO:1900019 1 0.032
regulation of protein secretion GO:0050708 82 0.031
acute inflammatory response GO:0002526 41 0.031
response to peptide GO:1901652 136 0.031
regulation of lipid biosynthetic process GO:0046890 54 0.031
aromatic compound catabolic process GO:0019439 286 0.031
nitrogen compound transport GO:0071705 271 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
regulation of renal output by angiotensin GO:0002019 2 0.030
triglyceride metabolic process GO:0006641 51 0.030
reactive oxygen species metabolic process GO:0072593 84 0.029
positive regulation of map kinase activity GO:0043406 84 0.029
positive regulation of innate immune response GO:0045089 80 0.029
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.029
defense response to other organism GO:0098542 197 0.028
defense response to gram positive bacterium GO:0050830 50 0.028
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.028
peptide metabolic process GO:0006518 46 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
transmembrane transport GO:0055085 412 0.028
fatty acid biosynthetic process GO:0006633 41 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
cellular response to peptide hormone stimulus GO:0071375 92 0.027
regulation of innate immune response GO:0045088 91 0.027
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.027
cellular macromolecule catabolic process GO:0044265 206 0.026
acylglycerol metabolic process GO:0006639 55 0.026
leukocyte activation involved in immune response GO:0002366 126 0.026
antimicrobial peptide biosynthetic process GO:0002777 2 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
protein catabolic process GO:0030163 221 0.026
blood vessel morphogenesis GO:0048514 285 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
cellular amine metabolic process GO:0044106 44 0.026
iron ion homeostasis GO:0055072 36 0.026
cofactor metabolic process GO:0051186 80 0.026
regulation of inflammatory response GO:0050727 147 0.025
cell killing GO:0001906 67 0.025
cofactor transport GO:0051181 4 0.025
humoral immune response GO:0006959 57 0.025
mapk cascade GO:0000165 281 0.025
lymphocyte differentiation GO:0030098 242 0.025
positive regulation of cell activation GO:0050867 158 0.025
fat cell differentiation GO:0045444 160 0.025
purine containing compound metabolic process GO:0072521 311 0.025
organic acid biosynthetic process GO:0016053 86 0.024
circulatory system process GO:0003013 197 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.024
response to testosterone GO:0033574 3 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
response to insulin GO:0032868 100 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
regulation of kinase activity GO:0043549 249 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.024
regulation of mapk cascade GO:0043408 248 0.024
cellular response to organonitrogen compound GO:0071417 145 0.023
adiponectin secretion GO:0070162 2 0.023
striated muscle cell development GO:0055002 125 0.023
lipid transport GO:0006869 98 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of systemic arterial blood pressure GO:0003073 61 0.023
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.023
blood coagulation GO:0007596 76 0.023
regulation of protein kinase activity GO:0045859 232 0.023
insulin receptor signaling pathway GO:0008286 49 0.023
inositol lipid mediated signaling GO:0048017 41 0.023
immunoglobulin mediated immune response GO:0016064 69 0.023
regulation of carbohydrate metabolic process GO:0006109 75 0.022
regulation of gluconeogenesis GO:0006111 30 0.022
adaptive immune response GO:0002250 155 0.022
positive regulation of protein activation cascade GO:2000259 2 0.022
muscle tissue development GO:0060537 308 0.022
regulation of natural killer cell mediated immunity GO:0002715 19 0.022
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.022
apoptotic signaling pathway GO:0097190 306 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
cell type specific apoptotic process GO:0097285 268 0.021
positive regulation of cytokine secretion GO:0050715 41 0.021
muscle cell differentiation GO:0042692 261 0.021
positive regulation of chemotaxis GO:0050921 38 0.021
defense response to bacterium GO:0042742 119 0.021
regulation of secretion by cell GO:1903530 249 0.021
regulation of organelle organization GO:0033043 289 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
antibacterial peptide biosynthetic process GO:0002780 2 0.020
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.020
chemotaxis GO:0006935 247 0.020
extracellular matrix organization GO:0030198 147 0.020
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.020
positive regulation of protein modification process GO:0031401 299 0.020
cellular amino acid metabolic process GO:0006520 103 0.020
regulation of endocytosis GO:0030100 69 0.020
phosphatidylinositol mediated signaling GO:0048015 41 0.020
regulation of anatomical structure size GO:0090066 178 0.020
macromolecule catabolic process GO:0009057 281 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
regulation of multi organism process GO:0043900 111 0.019
interferon gamma production GO:0032609 67 0.019
nucleotide metabolic process GO:0009117 332 0.019
regulation of system process GO:0044057 200 0.019
t cell activation GO:0042110 289 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
heterocycle catabolic process GO:0046700 280 0.019
glycosylation GO:0070085 62 0.019
positive regulation of type 2 immune response GO:0002830 9 0.019
negative regulation of angiogenesis GO:0016525 25 0.019
positive regulation of transferase activity GO:0051347 167 0.019
cellular chemical homeostasis GO:0055082 215 0.019
regulation of steroid metabolic process GO:0019218 39 0.019
interaction with symbiont GO:0051702 14 0.019
regulation of chemotaxis GO:0050920 53 0.019
extracellular structure organization GO:0043062 148 0.019
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.019
regulation of protein localization GO:0032880 231 0.018
t cell activation involved in immune response GO:0002286 43 0.018
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
steroid metabolic process GO:0008202 119 0.018
response to peptide hormone GO:0043434 127 0.018
regulation of protein transport GO:0051223 163 0.018
amine metabolic process GO:0009308 45 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
killing of cells of other organism GO:0031640 13 0.018
leukocyte migration GO:0050900 124 0.018
astrocyte activation GO:0048143 2 0.018
olfactory learning GO:0008355 2 0.018
anatomical structure homeostasis GO:0060249 145 0.018
negative regulation of cell activation GO:0050866 111 0.018
cellular response to lipid GO:0071396 145 0.018
negative regulation of defense response GO:0031348 77 0.018
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.018
regulation of adiponectin secretion GO:0070163 2 0.018
protein n linked glycosylation GO:0006487 12 0.017
positive regulation of kinase activity GO:0033674 155 0.017
response to steroid hormone GO:0048545 56 0.017
regulation of cellular response to stress GO:0080135 159 0.017
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
positive regulation of protein kinase c activity GO:1900020 1 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
positive regulation of inflammatory response GO:0050729 47 0.017
wound healing GO:0042060 157 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
carbohydrate homeostasis GO:0033500 128 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
germ cell development GO:0007281 185 0.016
regulation of response to wounding GO:1903034 189 0.016
positive regulation of leukocyte mediated immunity GO:0002705 70 0.016
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.016
positive regulation of camp mediated signaling GO:0043950 3 0.016
b cell mediated immunity GO:0019724 71 0.016
cation transport GO:0006812 399 0.016
lipid localization GO:0010876 126 0.016
regulation of humoral immune response GO:0002920 22 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of transferase activity GO:0051338 263 0.016
leukocyte differentiation GO:0002521 342 0.016
regulation of natural killer cell chemotaxis GO:2000501 1 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
metal ion homeostasis GO:0055065 189 0.016
thymocyte migration GO:0072679 2 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
negative regulation of growth GO:0045926 99 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
t helper 17 cell lineage commitment GO:0072540 4 0.016
cell activation involved in immune response GO:0002263 126 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
growth involved in symbiotic interaction GO:0044110 23 0.016
hormone metabolic process GO:0042445 86 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
negative regulation of fat cell differentiation GO:0045599 36 0.015
response to hypoxia GO:0001666 58 0.015
protein ubiquitination GO:0016567 171 0.015
regulation of defense response to bacterium GO:1900424 3 0.015
response to stilbenoid GO:0035634 22 0.015
negative regulation of cytokine production GO:0001818 84 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
nuclear transport GO:0051169 139 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
muscle cell development GO:0055001 133 0.015
small molecule biosynthetic process GO:0044283 132 0.015
positive regulation of acute inflammatory response GO:0002675 16 0.015
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of membrane potential GO:0042391 192 0.015
response to oxidative stress GO:0006979 123 0.015
renal sodium excretion GO:0035812 3 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.015
positive regulation of behavior GO:0048520 40 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
transition metal ion transport GO:0000041 38 0.015
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.015
spermatid development GO:0007286 108 0.015
negative regulation of epithelial cell proliferation GO:0050680 64 0.015
positive regulation of eosinophil migration GO:2000418 2 0.015
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.015
carbohydrate transport GO:0008643 62 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
alpha beta t cell activation involved in immune response GO:0002287 31 0.014
neutrophil mediated cytotoxicity GO:0070942 8 0.014
medium chain fatty acid metabolic process GO:0051791 1 0.014
collagen fibril organization GO:0030199 32 0.014
apoptotic cell clearance GO:0043277 17 0.014
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.014
striated muscle tissue development GO:0014706 293 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.014
cellular ion homeostasis GO:0006873 165 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.014
ear development GO:0043583 200 0.014
negative regulation of carbohydrate metabolic process GO:0045912 19 0.014
growth of symbiont in host GO:0044117 23 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
gland development GO:0048732 330 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
regulation of renal sodium excretion GO:0035813 3 0.014
rhythmic process GO:0048511 174 0.014
protein secretion GO:0009306 111 0.014
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.014
positive regulation of protein transport GO:0051222 93 0.014
mitochondrion organization GO:0007005 134 0.014
activation of mapk activity GO:0000187 59 0.014
hexose transport GO:0008645 56 0.014
activation of innate immune response GO:0002218 56 0.014
ion transmembrane transport GO:0034220 361 0.014
positive regulation of protein maturation GO:1903319 7 0.014
organ regeneration GO:0031100 2 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.014
ribonucleoside metabolic process GO:0009119 245 0.013
myeloid leukocyte activation GO:0002274 83 0.013
regulation of alpha beta t cell activation GO:0046634 53 0.013
cellular amide metabolic process GO:0043603 58 0.013
positive regulation of proteolysis GO:0045862 85 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
positive regulation of nervous system development GO:0051962 221 0.013
cellular response to gonadotropin stimulus GO:0071371 4 0.013
cellular protein catabolic process GO:0044257 155 0.013
renin angiotensin regulation of aldosterone production GO:0002018 3 0.013
regulation of protein catabolic process GO:0042176 108 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of blood pressure GO:0008217 93 0.013
carboxylic acid transport GO:0046942 100 0.013
regulation of protein complex assembly GO:0043254 83 0.013
cellular response to acid chemical GO:0071229 68 0.013
nucleoside metabolic process GO:0009116 246 0.013
positive regulation of cell killing GO:0031343 33 0.013
methylation GO:0032259 134 0.013
regulation of blood coagulation GO:0030193 28 0.013
disruption of cells of other organism GO:0044364 13 0.013
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.013
regulation of cell growth GO:0001558 91 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
amide transport GO:0042886 138 0.013
cell growth GO:0016049 130 0.012
protein methylation GO:0006479 81 0.012
regulation of body fluid levels GO:0050878 162 0.012
negative regulation of vasculature development GO:1901343 26 0.012
response to decreased oxygen levels GO:0036293 59 0.012
monosaccharide transport GO:0015749 58 0.012
response to oxygen levels GO:0070482 62 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
protein autoprocessing GO:0016540 2 0.012
viral process GO:0016032 41 0.012
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.012
protein oligomerization GO:0051259 67 0.012
astrocyte cell migration GO:0043615 3 0.012
response to drug GO:0042493 75 0.012
regulation of fatty acid biosynthetic process GO:0042304 12 0.012
negative regulation of lipoprotein lipase activity GO:0051005 1 0.012
cytokine biosynthetic process GO:0042089 68 0.012
regulation of interleukin 1 alpha production GO:0032650 4 0.012
regulation of growth of symbiont in host GO:0044126 19 0.012
response to phenylpropanoid GO:0080184 22 0.012
antigen processing and presentation of peptide antigen GO:0048002 29 0.012
interleukin 8 production GO:0032637 4 0.012
organic hydroxy compound transport GO:0015850 93 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
pattern recognition receptor signaling pathway GO:0002221 47 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
dna metabolic process GO:0006259 303 0.011
t cell proliferation GO:0042098 120 0.011
glucose transport GO:0015758 56 0.011
positive regulation of interferon gamma production GO:0032729 39 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.011
rna interference GO:0016246 2 0.011
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
coagulation GO:0050817 78 0.011
immune response activating signal transduction GO:0002757 116 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
neutrophil mediated killing of symbiont cell GO:0070943 8 0.011
protein localization to organelle GO:0033365 185 0.011
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.011
positive regulation of adiponectin secretion GO:0070165 1 0.011
cytokine metabolic process GO:0042107 71 0.011
negative regulation of interferon beta production GO:0032688 3 0.011
defense response to gram negative bacterium GO:0050829 28 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
spermatid differentiation GO:0048515 115 0.011
multicellular organismal signaling GO:0035637 91 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.011
cellular response to peptide GO:1901653 92 0.011
negative regulation of cell cycle GO:0045786 123 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
interleukin 12 secretion GO:0072610 3 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
positive regulation of glycogen metabolic process GO:0070875 8 0.011
cell chemotaxis GO:0060326 81 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
leukocyte chemotaxis GO:0030595 69 0.011
divalent inorganic cation transport GO:0072511 178 0.011
response to molecule of fungal origin GO:0002238 4 0.011
natural killer cell mediated immunity GO:0002228 29 0.011
positive regulation of t cell mediated immunity GO:0002711 24 0.011
t cell differentiation GO:0030217 174 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
nitric oxide biosynthetic process GO:0006809 25 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011

C2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.060
disease of anatomical entity DOID:7 0 0.060
sensory system disease DOID:0050155 0 0.035
eye and adnexa disease DOID:1492 0 0.034
eye disease DOID:5614 0 0.034
retinal degeneration DOID:8466 0 0.034
retinal disease DOID:5679 0 0.034
disease of metabolism DOID:0014667 0 0.032
immune system disease DOID:2914 0 0.032
hematopoietic system disease DOID:74 0 0.032
hemolytic anemia DOID:583 0 0.026
anemia DOID:2355 0 0.026
hemolytic uremic syndrome DOID:12554 0 0.026
normocytic anemia DOID:720 0 0.026
inherited metabolic disorder DOID:655 0 0.022
neurodegenerative disease DOID:1289 0 0.017
central nervous system disease DOID:331 0 0.017
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011