Mus musculus

151 known processes

C3

complement component 3

(Aliases: HSE-MSF,ASP,AI255234,Plp)

C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.980
immune effector process GO:0002252 321 0.967
humoral immune response GO:0006959 57 0.958
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.924
protein activation cascade GO:0072376 19 0.860
regulation of inflammatory response GO:0050727 147 0.845
positive regulation of protein phosphorylation GO:0001934 242 0.814
Human
hemostasis GO:0007599 78 0.783
complement activation GO:0006956 16 0.755
positive regulation of inflammatory response GO:0050729 47 0.755
activation of immune response GO:0002253 138 0.752
regulation of acute inflammatory response GO:0002673 27 0.745
fatty acid metabolic process GO:0006631 121 0.698
triglyceride metabolic process GO:0006641 51 0.687
Human
lymphocyte mediated immunity GO:0002449 139 0.683
regulation of cellular amino acid metabolic process GO:0006521 5 0.675
acute inflammatory response GO:0002526 41 0.675
cellular response to cytokine stimulus GO:0071345 189 0.674
defense response to gram positive bacterium GO:0050830 50 0.662
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.636
cholesterol metabolic process GO:0008203 56 0.636
inflammatory response GO:0006954 244 0.571
innate immune response GO:0045087 157 0.568
cdc42 protein signal transduction GO:0032488 0 0.542
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.531
positive regulation of cytokine production GO:0001819 174 0.530
Human
b cell mediated immunity GO:0019724 71 0.526
adaptive immune response GO:0002250 155 0.510
acylglycerol metabolic process GO:0006639 55 0.508
Human
regulation of kinase activity GO:0043549 249 0.500
regulation of angiogenesis GO:0045765 81 0.492
sterol metabolic process GO:0016125 58 0.492
regulation of cellular ketone metabolic process GO:0010565 66 0.489
regulation of lymphocyte mediated immunity GO:0002706 84 0.463
regulation of innate immune response GO:0045088 91 0.448
cytokine production GO:0001816 319 0.428
Human
apoptotic signaling pathway GO:0097190 306 0.421
acute inflammatory response to antigenic stimulus GO:0002438 12 0.421
negative regulation of defense response GO:0031348 77 0.418
divalent inorganic cation homeostasis GO:0072507 138 0.415
myeloid leukocyte activation GO:0002274 83 0.410
regulation of response to wounding GO:1903034 189 0.401
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.399
response to lipopolysaccharide GO:0032496 128 0.392
regulation of adaptive immune response GO:0002819 90 0.380
angiogenesis GO:0001525 201 0.376
positive regulation of defense response GO:0031349 124 0.366
cellular amine metabolic process GO:0044106 44 0.365
negative regulation of immune system process GO:0002683 209 0.336
regulation of cellular amine metabolic process GO:0033238 20 0.327
regulation of protein kinase activity GO:0045859 232 0.326
defense response to bacterium GO:0042742 119 0.323
positive regulation of protein kinase activity GO:0045860 144 0.321
cellular lipid metabolic process GO:0044255 323 0.297
Human
regulation of cytokine production involved in immune response GO:0002718 26 0.296
neuron apoptotic process GO:0051402 142 0.288
positive regulation of type ii hypersensitivity GO:0002894 4 0.288
cellular chemical homeostasis GO:0055082 215 0.286
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.276
positive regulation of kinase activity GO:0033674 155 0.271
positive regulation of cellular amine metabolic process GO:0033240 5 0.271
regulation of cell activation GO:0050865 289 0.268
defense response to other organism GO:0098542 197 0.267
positive regulation of sterol transport GO:0032373 9 0.267
oxidation reduction process GO:0055114 342 0.255
blood vessel morphogenesis GO:0048514 285 0.252
regulation of type ii hypersensitivity GO:0002892 4 0.247
positive regulation of immune effector process GO:0002699 107 0.240
regulation of endocytosis GO:0030100 69 0.238
regulation of cell motility GO:2000145 236 0.235
cation homeostasis GO:0055080 212 0.234
cellular ketone metabolic process GO:0042180 84 0.234
lipid modification GO:0030258 65 0.233
cytokine mediated signaling pathway GO:0019221 115 0.232
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.231
regulation of immunoglobulin mediated immune response GO:0002889 37 0.230
monocarboxylic acid metabolic process GO:0032787 191 0.227
granulocyte chemotaxis GO:0071621 39 0.221
blood coagulation GO:0007596 76 0.219
regulation of leukocyte proliferation GO:0070663 121 0.218
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.207
lymphocyte activation involved in immune response GO:0002285 93 0.206
wound healing GO:0042060 157 0.206
regulation of mapk cascade GO:0043408 248 0.204
regulation of blood coagulation GO:0030193 28 0.202
cell activation involved in immune response GO:0002263 126 0.195
immunoglobulin mediated immune response GO:0016064 69 0.194
stress activated protein kinase signaling cascade GO:0031098 81 0.193
epithelial cell proliferation GO:0050673 174 0.191
regulation of transferase activity GO:0051338 263 0.190
regulation of cytokine production GO:0001817 266 0.189
Human
positive regulation of response to wounding GO:1903036 66 0.188
gland development GO:0048732 330 0.187
cellular response to hormone stimulus GO:0032870 150 0.185
regulation of insulin receptor signaling pathway GO:0046626 21 0.182
leukocyte activation involved in immune response GO:0002366 126 0.178
regulation of cholesterol metabolic process GO:0090181 14 0.175
positive regulation of cell death GO:0010942 224 0.173
regulation of body fluid levels GO:0050878 162 0.173
response to molecule of bacterial origin GO:0002237 143 0.172
small molecule biosynthetic process GO:0044283 132 0.170
male gamete generation GO:0048232 285 0.169
regulation of interleukin 6 production GO:0032675 55 0.169
regulation of protein serine threonine kinase activity GO:0071900 157 0.168
regulation of stress activated mapk cascade GO:0032872 69 0.168
cellular response to organonitrogen compound GO:0071417 145 0.167
cellular response to molecule of bacterial origin GO:0071219 83 0.165
negative regulation of inflammatory response GO:0050728 61 0.164
cellular amino acid metabolic process GO:0006520 103 0.164
brown fat cell differentiation GO:0050873 36 0.159
positive regulation of mapk cascade GO:0043410 170 0.153
regulation of leukocyte mediated immunity GO:0002703 104 0.152
stress activated mapk cascade GO:0051403 80 0.150
positive regulation of transferase activity GO:0051347 167 0.150
cell type specific apoptotic process GO:0097285 268 0.149
positive regulation of cell activation GO:0050867 158 0.147
production of molecular mediator of immune response GO:0002440 103 0.147
response to tumor necrosis factor GO:0034612 26 0.146
cholesterol homeostasis GO:0042632 44 0.146
positive regulation of lymphocyte proliferation GO:0050671 70 0.146
growth involved in symbiotic interaction GO:0044110 23 0.142
mapk cascade GO:0000165 281 0.141
regulation of neuron apoptotic process GO:0043523 122 0.138
cytokine production involved in immune response GO:0002367 34 0.138
regulation of map kinase activity GO:0043405 120 0.137
amine metabolic process GO:0009308 45 0.136
glycerolipid metabolic process GO:0046486 122 0.136
Human
positive regulation of map kinase activity GO:0043406 84 0.133
positive regulation of innate immune response GO:0045089 80 0.131
lipid localization GO:0010876 126 0.130
Human
leukocyte differentiation GO:0002521 342 0.129
regulation of tumor necrosis factor production GO:0032680 49 0.129
regulation of secretion by cell GO:1903530 249 0.125
neuron death GO:0070997 154 0.124
positive regulation of activation of membrane attack complex GO:0001970 2 0.123
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.122
regulation of neuron death GO:1901214 134 0.121
phagocytosis GO:0006909 66 0.120
dendritic cell differentiation GO:0097028 26 0.120
positive regulation of interleukin 6 production GO:0032755 37 0.119
coagulation GO:0050817 78 0.118
positive regulation of type iia hypersensitivity GO:0001798 4 0.115
granulocyte migration GO:0097530 43 0.115
small gtpase mediated signal transduction GO:0007264 97 0.113
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.112
regulation of nucleocytoplasmic transport GO:0046822 73 0.112
regulation of reactive oxygen species metabolic process GO:2000377 40 0.111
lipid transport GO:0006869 98 0.111
regulation of lymphocyte activation GO:0051249 240 0.111
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.110
cellular response to insulin stimulus GO:0032869 78 0.108
regulation of jnk cascade GO:0046328 62 0.107
response to organonitrogen compound GO:0010243 246 0.107
cation transport GO:0006812 399 0.106
cytoplasmic transport GO:0016482 234 0.106
positive regulation of cytokine production involved in immune response GO:0002720 19 0.106
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.105
regulation of homeostatic process GO:0032844 182 0.105
positive regulation of leukocyte proliferation GO:0070665 73 0.105
positive regulation of cytokine secretion GO:0050715 41 0.104
positive regulation of adaptive immune response GO:0002821 61 0.104
regulation of fatty acid metabolic process GO:0019217 28 0.103
positive regulation of cell migration GO:0030335 109 0.102
metal ion homeostasis GO:0055065 189 0.102
positive regulation of type iii hypersensitivity GO:0001805 3 0.102
reverse cholesterol transport GO:0043691 6 0.102
positive regulation of leukocyte mediated immunity GO:0002705 70 0.101
positive regulation of lymphocyte activation GO:0051251 140 0.100
cellular response to peptide GO:1901653 92 0.100
positive regulation of cell motility GO:2000147 116 0.099
regulation of hemostasis GO:1900046 28 0.099
regulation of b cell mediated immunity GO:0002712 37 0.099
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.098
antigen processing and presentation GO:0019882 47 0.096
leukocyte mediated immunity GO:0002443 174 0.096
negative regulation of cholesterol transport GO:0032375 4 0.095
cell killing GO:0001906 67 0.094
anion transport GO:0006820 177 0.094
regulation of leukocyte differentiation GO:1902105 159 0.094
small molecule catabolic process GO:0044282 71 0.093
response to peptide hormone GO:0043434 127 0.092
homeostasis of number of cells GO:0048872 210 0.092
positive regulation of programmed cell death GO:0043068 218 0.092
cell cell adhesion GO:0098609 41 0.090
immune response regulating signaling pathway GO:0002764 125 0.090
lymphocyte proliferation GO:0046651 164 0.090
insulin receptor signaling pathway GO:0008286 49 0.090
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.089
myeloid cell differentiation GO:0030099 233 0.089
response to insulin GO:0032868 100 0.088
positive regulation of tumor necrosis factor production GO:0032760 30 0.088
gliogenesis GO:0042063 141 0.088
b cell activation GO:0042113 161 0.087
fat cell differentiation GO:0045444 160 0.087
ras protein signal transduction GO:0007265 77 0.087
myeloid leukocyte differentiation GO:0002573 119 0.086
negative regulation of neuron apoptotic process GO:0043524 92 0.086
organic anion transport GO:0015711 137 0.085
positive regulation of angiogenesis GO:0045766 46 0.083
response to interferon gamma GO:0034341 34 0.083
positive regulation of cholesterol transport GO:0032376 9 0.083
activation of mapk activity GO:0000187 59 0.082
peptidyl amino acid modification GO:0018193 336 0.081
cellular metal ion homeostasis GO:0006875 151 0.081
cholesterol efflux GO:0033344 24 0.081
positive regulation of beta amyloid formation GO:1902004 4 0.081
maintenance of location GO:0051235 89 0.080
Human
regulation of neutrophil chemotaxis GO:0090022 14 0.080
negative regulation of cytokine production GO:0001818 84 0.080
defense response to gram negative bacterium GO:0050829 28 0.079
protein lipid complex subunit organization GO:0071825 12 0.079
t cell activation GO:0042110 289 0.079
positive regulation of neuron apoptotic process GO:0043525 25 0.079
cellular calcium ion homeostasis GO:0006874 119 0.079
positive regulation of phagocytosis GO:0050766 26 0.078
negative regulation of cell proliferation GO:0008285 296 0.078
negative regulation of cellular amide metabolic process GO:0034249 4 0.078
urogenital system development GO:0001655 261 0.078
carbohydrate metabolic process GO:0005975 230 0.078
positive regulation of presynaptic membrane organization GO:1901631 1 0.078
spermatogenesis GO:0007283 284 0.077
regulation of cytokine biosynthetic process GO:0042035 59 0.077
cellular homeostasis GO:0019725 240 0.076
glycerolipid biosynthetic process GO:0045017 50 0.076
Human
alcohol metabolic process GO:0006066 116 0.076
sterol homeostasis GO:0055092 45 0.076
regulation of endopeptidase activity GO:0052548 89 0.074
Mouse
positive regulation of t cell activation GO:0050870 101 0.074
regulation of secretion GO:0051046 274 0.074
regulation of epithelial cell proliferation GO:0050678 141 0.073
endocytosis GO:0006897 168 0.073
positive regulation of acute inflammatory response GO:0002675 16 0.072
cell adhesion GO:0007155 329 0.072
reactive oxygen species metabolic process GO:0072593 84 0.072
regulation of establishment of protein localization GO:0070201 181 0.072
leukocyte proliferation GO:0070661 172 0.071
cytokine biosynthetic process GO:0042089 68 0.070
response to nutrient levels GO:0031667 109 0.070
negative regulation of intracellular signal transduction GO:1902532 167 0.070
lipid homeostasis GO:0055088 63 0.070
regulation of protein transport GO:0051223 163 0.070
i kappab kinase nf kappab signaling GO:0007249 85 0.069
negative regulation of response to wounding GO:1903035 77 0.069
epithelial tube morphogenesis GO:0060562 303 0.069
regulation of removal of superoxide radicals GO:2000121 4 0.069
cholesterol esterification GO:0034435 3 0.069
positive regulation of cytokine biosynthetic process GO:0042108 40 0.069
hepaticobiliary system development GO:0061008 67 0.068
regulation of beta amyloid clearance GO:1900221 1 0.068
hexose metabolic process GO:0019318 98 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
negative regulation of immune effector process GO:0002698 55 0.068
response to monosaccharide GO:0034284 67 0.067
cytokine secretion GO:0050663 72 0.067
regulation of protein kinase c activity GO:1900019 1 0.067
positive regulation of epithelial cell proliferation GO:0050679 68 0.066
muscle cell differentiation GO:0042692 261 0.066
leukocyte migration GO:0050900 124 0.066
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.066
complement activation lectin pathway GO:0001867 5 0.065
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.064
sterol transport GO:0015918 38 0.064
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.063
fatty acid biosynthetic process GO:0006633 41 0.063
regulation of t cell activation GO:0050863 170 0.063
tumor necrosis factor biosynthetic process GO:0042533 10 0.062
t cell mediated immunity GO:0002456 50 0.062
regulation of b cell activation GO:0050864 81 0.062
chemotaxis GO:0006935 247 0.061
response to radiation GO:0009314 165 0.061
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.060
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.060
positive regulation of stress activated mapk cascade GO:0032874 48 0.060
regulation of cell migration GO:0030334 219 0.059
positive regulation of t cell proliferation GO:0042102 52 0.059
regulation of proteolysis GO:0030162 164 0.059
Mouse
response to organic cyclic compound GO:0014070 198 0.059
interleukin 1 production GO:0032612 31 0.058
urea cycle GO:0000050 2 0.058
positive regulation of secretion by cell GO:1903532 114 0.058
reactive nitrogen species metabolic process GO:2001057 0 0.058
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.057
plasma lipoprotein particle remodeling GO:0034369 6 0.057
steroid metabolic process GO:0008202 119 0.057
cellular ion homeostasis GO:0006873 165 0.057
response to metal ion GO:0010038 47 0.057
negative regulation of cellular amine metabolic process GO:0033239 1 0.057
regulation of lymphocyte proliferation GO:0050670 117 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.056
cellular response to lipid GO:0071396 145 0.056
interspecies interaction between organisms GO:0044419 83 0.055
striated muscle tissue development GO:0014706 293 0.055
regulation of growth of symbiont in host GO:0044126 19 0.055
positive regulation of apoptotic process GO:0043065 217 0.055
jnk cascade GO:0007254 72 0.055
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.055
regulation of protein secretion GO:0050708 82 0.055
negative regulation of molecular function GO:0044092 258 0.055
Mouse
interleukin 8 production GO:0032637 4 0.055
tumor necrosis factor production GO:0032640 50 0.054
positive regulation of toll like receptor 4 signaling pathway GO:0034145 1 0.054
tissue homeostasis GO:0001894 115 0.054
tissue migration GO:0090130 68 0.054
protein targeting GO:0006605 143 0.054
extracellular structure organization GO:0043062 148 0.054
peptidyl serine modification GO:0018209 83 0.052
positive regulation of secretion GO:0051047 130 0.052
nucleotide metabolic process GO:0009117 332 0.052
steroid esterification GO:0034433 3 0.052
regulation of production of molecular mediator of immune response GO:0002700 65 0.052
hexose biosynthetic process GO:0019319 39 0.051
cellular response to acid chemical GO:0071229 68 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.051
kidney development GO:0001822 213 0.051
liver development GO:0001889 66 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.050
extrinsic apoptotic signaling pathway GO:0097191 126 0.050
regulation of cellular response to stress GO:0080135 159 0.050
calcium ion transport GO:0006816 159 0.050
cellular response to dna damage stimulus GO:0006974 207 0.050
fat soluble vitamin biosynthetic process GO:0042362 4 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.049
negative regulation of growth GO:0045926 99 0.049
regulation of coagulation GO:0050818 31 0.049
positive regulation of hypersensitivity GO:0002885 7 0.049
negative regulation of innate immune response GO:0045824 17 0.049
multicellular organismal homeostasis GO:0048871 164 0.049
positive regulation of amyloid precursor protein catabolic process GO:1902993 4 0.048
cellular response to external stimulus GO:0071496 88 0.048
positive regulation of interleukin 12 production GO:0032735 21 0.048
negative regulation of phosphorus metabolic process GO:0010563 184 0.048
positive regulation of jnk cascade GO:0046330 46 0.047
sterol esterification GO:0034434 3 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
response to steroid hormone GO:0048545 56 0.047
leukocyte mediated cytotoxicity GO:0001909 62 0.047
cellular amide metabolic process GO:0043603 58 0.047
immune response activating signal transduction GO:0002757 116 0.047
toll like receptor 4 signaling pathway GO:0034142 9 0.046
regulation of vasculature development GO:1901342 88 0.046
membrane organization GO:0061024 245 0.046
cellular divalent inorganic cation homeostasis GO:0072503 127 0.046
triglyceride homeostasis GO:0070328 15 0.045
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
protein localization to organelle GO:0033365 185 0.045
inflammatory response to antigenic stimulus GO:0002437 30 0.045
response to growth factor GO:0070848 198 0.045
negative regulation of phosphorylation GO:0042326 166 0.044
negative regulation of endothelial cell migration GO:0010596 4 0.044
acylglycerol homeostasis GO:0055090 16 0.044
cell substrate adhesion GO:0031589 130 0.044
negative regulation of protein modification process GO:0031400 163 0.043
regulation of toll like receptor signaling pathway GO:0034121 20 0.043
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.043
regulation of carbohydrate metabolic process GO:0006109 75 0.043
organic hydroxy compound metabolic process GO:1901615 203 0.043
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.043
positive regulation of monocyte chemotaxis GO:0090026 2 0.043
positive regulation of protein modification process GO:0031401 299 0.042
Human
glucose metabolic process GO:0006006 92 0.042
negative regulation of protein metabolic process GO:0051248 282 0.042
Mouse
response to low density lipoprotein particle GO:0055098 2 0.042
protein lipid complex remodeling GO:0034368 6 0.042
myeloid leukocyte mediated immunity GO:0002444 42 0.042
long chain fatty acid transport GO:0015909 15 0.042
divalent inorganic cation transport GO:0072511 178 0.042
regulation of ossification GO:0030278 112 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
Mouse
glial cell differentiation GO:0010001 131 0.042
production of molecular mediator involved in inflammatory response GO:0002532 21 0.041
regulation of ion transport GO:0043269 215 0.041
protein secretion GO:0009306 111 0.041
response to acid chemical GO:0001101 111 0.041
positive regulation of apoptotic signaling pathway GO:2001235 95 0.041
regulation of type iii hypersensitivity GO:0001803 3 0.041
regulation of glucose metabolic process GO:0010906 60 0.041
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
placenta development GO:0001890 140 0.041
icosanoid biosynthetic process GO:0046456 15 0.041
detection of molecule of bacterial origin GO:0032490 2 0.041
positive regulation of nervous system development GO:0051962 221 0.041
interleukin 6 production GO:0032635 58 0.041
purine nucleoside metabolic process GO:0042278 241 0.041
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.040
peptide metabolic process GO:0006518 46 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
negative regulation of multi organism process GO:0043901 68 0.040
regulation of leukocyte apoptotic process GO:2000106 56 0.040
organic acid biosynthetic process GO:0016053 86 0.040
response to bacterial lipoprotein GO:0032493 4 0.040
positive regulation of glial cell proliferation GO:0060252 4 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
positive regulation of cellular catabolic process GO:0031331 148 0.039
cellular response to peptidoglycan GO:0071224 4 0.039
response to drug GO:0042493 75 0.039
protein localization to nucleus GO:0034504 121 0.039
reactive oxygen species biosynthetic process GO:1903409 8 0.039
regulation of t helper 2 cell cytokine production GO:2000551 3 0.039
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.039
dna metabolic process GO:0006259 303 0.038
positive regulation of interferon alpha production GO:0032727 4 0.038
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.038
cellular response to amino acid stimulus GO:0071230 29 0.038
regulation of alpha beta t cell proliferation GO:0046640 18 0.038
cellular response to organic cyclic compound GO:0071407 87 0.038
monosaccharide biosynthetic process GO:0046364 44 0.038
antigen processing and presentation of exogenous antigen GO:0019884 26 0.038
calcium ion homeostasis GO:0055074 127 0.038
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.038
carbohydrate homeostasis GO:0033500 128 0.037
glycoprotein metabolic process GO:0009100 116 0.037
ribose phosphate biosynthetic process GO:0046390 59 0.037
heterocycle catabolic process GO:0046700 280 0.037
regulation of chemotaxis GO:0050920 53 0.037
glial cell apoptotic process GO:0034349 3 0.037
positive regulation of protein secretion GO:0050714 52 0.037
regulation of hydrolase activity GO:0051336 246 0.037
Mouse
glucose homeostasis GO:0042593 128 0.037
glycoprotein biosynthetic process GO:0009101 89 0.037
lipoprotein metabolic process GO:0042157 43 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
organonitrogen compound biosynthetic process GO:1901566 192 0.036
negative regulation of endopeptidase activity GO:0010951 44 0.036
Mouse
glucocorticoid metabolic process GO:0008211 9 0.036
morphogenesis of a branching epithelium GO:0061138 193 0.036
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.036
positive regulation of jun kinase activity GO:0043507 30 0.036
regulation of cellular catabolic process GO:0031329 242 0.036
multicellular organism growth GO:0035264 161 0.036
response to ionizing radiation GO:0010212 42 0.035
negative regulation of angiogenesis GO:0016525 25 0.035
regulation of cholesterol esterification GO:0010872 2 0.035
regulation of inclusion body assembly GO:0090083 1 0.035
response to amino acid GO:0043200 37 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
purine containing compound metabolic process GO:0072521 311 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.035
myeloid cell homeostasis GO:0002262 114 0.035
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.035
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 9 0.034
beta amyloid clearance GO:0097242 2 0.034
regulation of b cell proliferation GO:0030888 39 0.034
regulation of blood pressure GO:0008217 93 0.034
hindbrain morphogenesis GO:0021575 46 0.034
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.034
osteoclast differentiation GO:0030316 62 0.034
negative regulation of cell activation GO:0050866 111 0.034
leukocyte apoptotic process GO:0071887 71 0.034
guanosine containing compound catabolic process GO:1901069 144 0.034
positive regulation of t cell differentiation GO:0045582 52 0.034
morphogenesis of a branching structure GO:0001763 203 0.034
neutrophil migration GO:1990266 37 0.033
organic acid catabolic process GO:0016054 51 0.033
organic hydroxy compound transport GO:0015850 93 0.033
fatty acid derivative biosynthetic process GO:1901570 15 0.033
positive regulation of neuron death GO:1901216 28 0.033
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.033
ear development GO:0043583 200 0.033
interleukin 12 production GO:0032615 32 0.033
sequestering of calcium ion GO:0051208 18 0.033
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.033
lung development GO:0030324 164 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
axonogenesis GO:0007409 274 0.032
negative regulation of hypersensitivity GO:0002884 3 0.032
regulation of interleukin 8 production GO:0032677 3 0.032
interleukin 5 secretion GO:0072603 2 0.032
nitrogen compound transport GO:0071705 271 0.032
renal system development GO:0072001 225 0.032
skin development GO:0043588 220 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.032
positive regulation of protein kinase c activity GO:1900020 1 0.032
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.032
metanephric glomerular visceral epithelial cell differentiation GO:0072248 2 0.032
pattern recognition receptor signaling pathway GO:0002221 47 0.032

C3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.343
Human
disease of anatomical entity DOID:7 0 0.343
Human
disease of metabolism DOID:0014667 0 0.236
inherited metabolic disorder DOID:655 0 0.236
nervous system disease DOID:863 0 0.219
Human
hemolytic anemia DOID:583 0 0.154
Human
hemolytic uremic syndrome DOID:12554 0 0.154
Human
normocytic anemia DOID:720 0 0.154
Human
anemia DOID:2355 0 0.154
Human
hematopoietic system disease DOID:74 0 0.154
Human
disease by infectious agent DOID:0050117 0 0.076
musculoskeletal system disease DOID:17 0 0.055
central nervous system disease DOID:331 0 0.045
sensory system disease DOID:0050155 0 0.039
Human
eye and adnexa disease DOID:1492 0 0.039
Human
hypersensitivity reaction disease DOID:0060056 0 0.035
neurodegenerative disease DOID:1289 0 0.034