Mus musculus

0 known processes

C8a

complement component 8, alpha polypeptide

(Aliases: MGC29381)

C8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to stilbenoid GO:0035634 22 0.185
activation of membrane attack complex GO:0001905 4 0.182
Mouse
protein processing GO:0016485 163 0.175
Mouse
glucuronate metabolic process GO:0019585 2 0.165
small molecule biosynthetic process GO:0044283 132 0.138
positive regulation of activation of membrane attack complex GO:0001970 2 0.137
Mouse
regulation of response to wounding GO:1903034 189 0.134
Mouse
oxidation reduction process GO:0055114 342 0.118
coagulation GO:0050817 78 0.116
lipid biosynthetic process GO:0008610 179 0.115
organic hydroxy compound metabolic process GO:1901615 203 0.114
monocarboxylic acid metabolic process GO:0032787 191 0.111
regulation of protein maturation GO:1903317 96 0.111
Mouse
protein maturation GO:0051604 176 0.109
Mouse
cellular lipid metabolic process GO:0044255 323 0.099
hemostasis GO:0007599 78 0.099
cellular response to hormone stimulus GO:0032870 150 0.096
naphthalene containing compound metabolic process GO:0090420 1 0.092
immune effector process GO:0002252 321 0.084
Human Mouse
regulation of protein processing GO:0070613 96 0.077
Mouse
steroid metabolic process GO:0008202 119 0.076
wound healing GO:0042060 157 0.074
response to peptide GO:1901652 136 0.074
carbohydrate metabolic process GO:0005975 230 0.074
protein catabolic process GO:0030163 221 0.068
neutral lipid metabolic process GO:0006638 57 0.068
negative regulation of protein metabolic process GO:0051248 282 0.067
response to organic cyclic compound GO:0014070 198 0.067
uronic acid metabolic process GO:0006063 2 0.065
carboxylic acid biosynthetic process GO:0046394 86 0.065
negative regulation of cellular protein metabolic process GO:0032269 247 0.063
regulation of hormone levels GO:0010817 211 0.061
cellular amine metabolic process GO:0044106 44 0.057
regulation of proteolysis GO:0030162 164 0.057
organic acid biosynthetic process GO:0016053 86 0.053
negative regulation of molecular function GO:0044092 258 0.053
blood coagulation GO:0007596 76 0.053
response to phenylpropanoid GO:0080184 22 0.053
fatty acid metabolic process GO:0006631 121 0.050
macromolecule catabolic process GO:0009057 281 0.050
monocarboxylic acid biosynthetic process GO:0072330 61 0.050
response to testosterone GO:0033574 3 0.049
response to acid chemical GO:0001101 111 0.049
organic cyclic compound catabolic process GO:1901361 295 0.047
regulation of body fluid levels GO:0050878 162 0.045
establishment of blood nerve barrier GO:0008065 3 0.044
positive regulation of complement activation GO:0045917 2 0.044
Mouse
fibrinolysis GO:0042730 3 0.044
regulation of hydrolase activity GO:0051336 246 0.043
regulation of anatomical structure size GO:0090066 178 0.041
negative regulation of endopeptidase activity GO:0010951 44 0.041
negative regulation of protein maturation GO:1903318 79 0.040
nitrogen compound transport GO:0071705 271 0.040
negative regulation of peptidase activity GO:0010466 46 0.039
amine metabolic process GO:0009308 45 0.039
cellular ketone metabolic process GO:0042180 84 0.039
negative regulation of proteolysis GO:0045861 74 0.039
cholesterol metabolic process GO:0008203 56 0.038
regulation of defense response GO:0031347 233 0.038
Mouse
renal tubular secretion GO:0097254 2 0.038
regulation of blood coagulation GO:0030193 28 0.037
negative regulation of protein processing GO:0010955 79 0.036
urogenital system development GO:0001655 261 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.035
response to peptide hormone GO:0043434 127 0.035
regulation of lipid metabolic process GO:0019216 118 0.034
monosaccharide metabolic process GO:0005996 106 0.033
regulation of cell adhesion GO:0030155 154 0.033
lipid catabolic process GO:0016042 69 0.033
diterpenoid metabolic process GO:0016101 24 0.032
inflammatory response GO:0006954 244 0.032
Mouse
regulation of inflammatory response GO:0050727 147 0.032
Mouse
regulation of vasculature development GO:1901342 88 0.031
Mouse
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.031
sterol metabolic process GO:0016125 58 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
naphthalene metabolic process GO:0018931 1 0.030
cell adhesion GO:0007155 329 0.030
diterpenoid biosynthetic process GO:0016102 7 0.030
positive regulation of protein activation cascade GO:2000259 2 0.030
Mouse
regulation of peptidase activity GO:0052547 96 0.030
regulation of complement activation GO:0030449 7 0.030
Mouse
protein activation cascade GO:0072376 19 0.029
Human Mouse
spermatogenesis GO:0007283 284 0.028
regulation of wound healing GO:0061041 40 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
aromatic compound catabolic process GO:0019439 286 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
extracellular structure organization GO:0043062 148 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
heterocycle catabolic process GO:0046700 280 0.027
cellular alcohol biosynthetic process GO:0044108 3 0.027
fat soluble vitamin biosynthetic process GO:0042362 4 0.027
regulation of endopeptidase activity GO:0052548 89 0.027
cofactor metabolic process GO:0051186 80 0.027
transmembrane transport GO:0055085 412 0.027
cellular response to peptide hormone stimulus GO:0071375 92 0.026
immunoglobulin mediated immune response GO:0016064 69 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
acylglycerol metabolic process GO:0006639 55 0.026
regulation of lymphocyte mediated immunity GO:0002706 84 0.026
blood circulation GO:0008015 195 0.025
extracellular matrix organization GO:0030198 147 0.025
negative regulation of response to wounding GO:1903035 77 0.025
purine containing compound metabolic process GO:0072521 311 0.025
cellular response to peptide GO:1901653 92 0.025
response to inorganic substance GO:0010035 96 0.024
angiogenesis GO:0001525 201 0.024
Mouse
positive regulation of response to wounding GO:1903036 66 0.024
cellular response to lipid GO:0071396 145 0.024
endocytosis GO:0006897 168 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
regulation of fibrinolysis GO:0051917 1 0.024
negative regulation of hydrolase activity GO:0051346 71 0.024
response to organonitrogen compound GO:0010243 246 0.024
cell type specific apoptotic process GO:0097285 268 0.023
vitamin d biosynthetic process GO:0042368 3 0.023
maintenance of location GO:0051235 89 0.023
regulation of protein kinase activity GO:0045859 232 0.023
activation of mapk activity involved in innate immune response GO:0035419 2 0.023
regulation of hemostasis GO:1900046 28 0.023
negative regulation of immune system process GO:0002683 209 0.023
acute inflammatory response GO:0002526 41 0.023
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
alcohol metabolic process GO:0006066 116 0.022
regulation of blood vessel size GO:0050880 56 0.022
regulation of coagulation GO:0050818 31 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
regulation of plasminogen activation GO:0010755 4 0.022
regulation of kinase activity GO:0043549 249 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
cytokine production GO:0001816 319 0.022
cellular response to organonitrogen compound GO:0071417 145 0.021
positive regulation of steroid hormone secretion GO:2000833 2 0.021
male gamete generation GO:0048232 285 0.021
response to steroid hormone GO:0048545 56 0.021
response to metal ion GO:0010038 47 0.021
regulation of secretion GO:0051046 274 0.021
gland development GO:0048732 330 0.021
regulation of blood pressure GO:0008217 93 0.021
hormone metabolic process GO:0042445 86 0.021
organophosphate catabolic process GO:0046434 232 0.021
macromolecule glycosylation GO:0043413 55 0.021
positive regulation of protein modification process GO:0031401 299 0.021
nucleotide catabolic process GO:0009166 217 0.021
carnitine transmembrane transport GO:1902603 3 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
lipid localization GO:0010876 126 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
positive regulation of protein maturation GO:1903319 7 0.020
Mouse
retinoid metabolic process GO:0001523 24 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
innate immune response GO:0045087 157 0.020
isoprenoid metabolic process GO:0006720 29 0.020
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.019
fatty acid derivative metabolic process GO:1901568 33 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
multicellular organism growth GO:0035264 161 0.019
nucleoside catabolic process GO:0009164 206 0.019
anion transport GO:0006820 177 0.019
sulfur compound metabolic process GO:0006790 100 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
sensory organ morphogenesis GO:0090596 242 0.019
response to radiation GO:0009314 165 0.019
glycoprotein metabolic process GO:0009100 116 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
actin filament organization GO:0007015 113 0.018
purine containing compound catabolic process GO:0072523 213 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
mapk cascade GO:0000165 281 0.018
lipid transport GO:0006869 98 0.018
blood vessel morphogenesis GO:0048514 285 0.018
Mouse
negative regulation of fibrinolysis GO:0051918 1 0.018
neurotransmitter transport GO:0006836 76 0.018
regulation of jnk cascade GO:0046328 62 0.018
liver development GO:0001889 66 0.018
insulin receptor signaling pathway GO:0008286 49 0.018
response to insulin GO:0032868 100 0.017
regulation of organelle organization GO:0033043 289 0.017
apoptotic signaling pathway GO:0097190 306 0.017
renal system development GO:0072001 225 0.017
vitamin d3 metabolic process GO:0070640 3 0.017
cellular homeostasis GO:0019725 240 0.017
regulation of angiogenesis GO:0045765 81 0.017
Mouse
vascular process in circulatory system GO:0003018 62 0.017
regulation of cell activation GO:0050865 289 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
inter male aggressive behavior GO:0002121 3 0.016
leukocyte mediated immunity GO:0002443 174 0.016
rhythmic process GO:0048511 174 0.016
cellular response to testosterone stimulus GO:0071394 1 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
positive regulation of protein transport GO:0051222 93 0.016
zymogen activation GO:0031638 41 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
positive regulation of cytokine production GO:0001819 174 0.016
nucleotide metabolic process GO:0009117 332 0.016
regulation of tube size GO:0035150 57 0.016
regulation of actin filament based process GO:0032970 99 0.016
gonad development GO:0008406 141 0.016
positive regulation of apoptotic process GO:0043065 217 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
negative regulation of cell development GO:0010721 169 0.015
photoreceptor cell development GO:0042461 40 0.015
sulfur compound biosynthetic process GO:0044272 37 0.015
glycosylation GO:0070085 62 0.015
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.015
regulation of endocytosis GO:0030100 69 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
muscle tissue development GO:0060537 308 0.015
female gamete generation GO:0007292 74 0.015
protein oligomerization GO:0051259 67 0.015
sensory perception GO:0007600 245 0.015
circulatory system process GO:0003013 197 0.015
cellular chemical homeostasis GO:0055082 215 0.015
hexose metabolic process GO:0019318 98 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
amide transport GO:0042886 138 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of cell cycle GO:0051726 281 0.015
skeletal system morphogenesis GO:0048705 203 0.015
triglyceride metabolic process GO:0006641 51 0.015
small molecule catabolic process GO:0044282 71 0.015
regulation of transferase activity GO:0051338 263 0.015
terpenoid biosynthetic process GO:0016114 7 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
cellular response to cadmium ion GO:0071276 3 0.014
endothelium development GO:0003158 45 0.014
atp catabolic process GO:0006200 55 0.014
regulation of systemic arterial blood pressure GO:0003073 61 0.014
cell recognition GO:0008037 83 0.014
cellular response to ethanol GO:0071361 3 0.014
organic hydroxy compound transport GO:0015850 93 0.014
icosanoid metabolic process GO:0006690 33 0.014
urate transport GO:0015747 1 0.014
terpenoid metabolic process GO:0006721 25 0.014
positive regulation of cell death GO:0010942 224 0.014
nuclear division GO:0000280 158 0.014
regulation of secretion by cell GO:1903530 249 0.014
organic acid transport GO:0015849 101 0.014
regulation of cellular response to stress GO:0080135 159 0.014
rho protein signal transduction GO:0007266 32 0.013
unsaturated fatty acid metabolic process GO:0033559 31 0.013
testosterone biosynthetic process GO:0061370 2 0.013
response to amino acid GO:0043200 37 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
protein localization to organelle GO:0033365 185 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
positive regulation of kinase activity GO:0033674 155 0.013
protein glycosylation GO:0006486 55 0.013
carboxylic acid transport GO:0046942 100 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
regulation of system process GO:0044057 200 0.013
negative regulation of endothelial cell migration GO:0010596 4 0.013
humoral immune response GO:0006959 57 0.013
Human Mouse
organelle localization GO:0051640 179 0.013
response to growth factor GO:0070848 198 0.013
regulation of mapk cascade GO:0043408 248 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.013
porphyrin containing compound metabolic process GO:0006778 22 0.013
cell matrix adhesion GO:0007160 68 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
phagocytosis GO:0006909 66 0.013
carboxylic acid catabolic process GO:0046395 51 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
regulation of protein localization GO:0032880 231 0.013
secondary alcohol metabolic process GO:1902652 3 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
arachidonic acid metabolic process GO:0019369 14 0.013
response to lipopolysaccharide GO:0032496 128 0.013
positive regulation of secretion GO:0051047 130 0.012
actin cytoskeleton organization GO:0030036 220 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
olfactory learning GO:0008355 2 0.012
regulation of neuron death GO:1901214 134 0.012
cation transmembrane transport GO:0098655 266 0.012
phospholipid metabolic process GO:0006644 87 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of protein transport GO:0051223 163 0.012
long chain fatty acid metabolic process GO:0001676 26 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
positive regulation of immune effector process GO:0002699 107 0.012
Mouse
mitotic cell cycle GO:0000278 195 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
peripheral nervous system development GO:0007422 53 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
ras protein signal transduction GO:0007265 77 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
regulation of humoral immune response GO:0002920 22 0.012
Mouse
regulation of cell projection organization GO:0031344 206 0.012
regulation of acute inflammatory response GO:0002673 27 0.012
Mouse
interleukin 8 production GO:0032637 4 0.012
regulation of b cell mediated immunity GO:0002712 37 0.012
response to extracellular stimulus GO:0009991 127 0.012
cellular response to inorganic substance GO:0071241 37 0.012
nuclear transport GO:0051169 139 0.012
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.012
meiotic nuclear division GO:0007126 115 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
spinal cord motor neuron migration GO:0097476 4 0.011
regulation of cytokine production GO:0001817 266 0.011
skeletal system development GO:0001501 356 0.011
cellular protein complex assembly GO:0043623 116 0.011
cellular lipid catabolic process GO:0044242 52 0.011
organelle fission GO:0048285 170 0.011
glucose homeostasis GO:0042593 128 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
hepaticobiliary system development GO:0061008 67 0.011
t cell activation GO:0042110 289 0.011
cell substrate adhesion GO:0031589 130 0.011
type b pancreatic cell proliferation GO:0044342 10 0.011
cognition GO:0050890 149 0.011
regulation of protein secretion GO:0050708 82 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
mrna metabolic process GO:0016071 84 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
epithelial cell proliferation GO:0050673 174 0.011
nucleoside metabolic process GO:0009116 246 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
short chain fatty acid catabolic process GO:0019626 2 0.011
membrane organization GO:0061024 245 0.011
eye photoreceptor cell development GO:0042462 31 0.011
protein secretion GO:0009306 111 0.011
atp metabolic process GO:0046034 75 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
negative regulation of carbohydrate metabolic process GO:0045912 19 0.011
cellular glucose homeostasis GO:0001678 52 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
circadian rhythm GO:0007623 114 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
learning or memory GO:0007611 148 0.011
cellular response to carbohydrate stimulus GO:0071322 50 0.011
regulation of immunoglobulin mediated immune response GO:0002889 37 0.011
heme metabolic process GO:0042168 16 0.011
rna processing GO:0006396 105 0.011
eye photoreceptor cell differentiation GO:0001754 41 0.011
response to nutrient levels GO:0031667 109 0.011
complement activation GO:0006956 16 0.011
Human Mouse
response to drug GO:0042493 75 0.011
germ cell development GO:0007281 185 0.011
positive regulation of phagocytosis GO:0050766 26 0.010
regulation of insulin receptor signaling pathway GO:0046626 21 0.010
response to light stimulus GO:0009416 135 0.010
connective tissue development GO:0061448 179 0.010
organic anion transport GO:0015711 137 0.010
regulation of protein catabolic process GO:0042176 108 0.010
regulation of cell motility GO:2000145 236 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
metanephric loop of henle development GO:0072236 4 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
protein import into nucleus GO:0006606 95 0.010
pigment metabolic process GO:0042440 32 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.010
kidney development GO:0001822 213 0.010
mitochondrion organization GO:0007005 134 0.010
platelet activation GO:0030168 40 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
ion transmembrane transport GO:0034220 361 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
muscle fiber development GO:0048747 76 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
9 cis retinoic acid metabolic process GO:0042905 5 0.010
adaptive immune response GO:0002250 155 0.010
regulation of neuron differentiation GO:0045664 281 0.010
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
negative regulation of hemostasis GO:1900047 11 0.010
negative regulation of immune effector process GO:0002698 55 0.010

C8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.054
inherited metabolic disorder DOID:655 0 0.028
nervous system disease DOID:863 0 0.024
disease of anatomical entity DOID:7 0 0.024
acquired metabolic disease DOID:0060158 0 0.014
eye and adnexa disease DOID:1492 0 0.013
sensory system disease DOID:0050155 0 0.013
congenital adrenal hyperplasia DOID:0050811 0 0.012
lipid metabolism disorder DOID:3146 0 0.012
steroid inherited metabolic disorder DOID:1701 0 0.012
immune system disease DOID:2914 0 0.011