Mus musculus

0 known processes

C8b

complement component 8, beta polypeptide

(Aliases: AI595927,4930439B20Rik)

C8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein maturation GO:0051604 176 0.193
Mouse
regulation of protein maturation GO:1903317 96 0.113
Mouse
cellular ketone metabolic process GO:0042180 84 0.098
lipid biosynthetic process GO:0008610 179 0.093
spermatogenesis GO:0007283 284 0.092
fibrinolysis GO:0042730 3 0.088
regulation of mapk cascade GO:0043408 248 0.088
terpenoid metabolic process GO:0006721 25 0.085
cell adhesion GO:0007155 329 0.082
cellular amino acid metabolic process GO:0006520 103 0.082
regulation of protein kinase activity GO:0045859 232 0.080
carbohydrate metabolic process GO:0005975 230 0.076
positive regulation of transferase activity GO:0051347 167 0.075
regulation of proteolysis GO:0030162 164 0.072
cellular lipid metabolic process GO:0044255 323 0.071
amine metabolic process GO:0009308 45 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.071
positive regulation of activation of membrane attack complex GO:0001970 2 0.069
Mouse
protein processing GO:0016485 163 0.069
Mouse
neutral lipid metabolic process GO:0006638 57 0.069
transmembrane transport GO:0055085 412 0.068
Mouse
cellular amine metabolic process GO:0044106 44 0.068
regulation of protein serine threonine kinase activity GO:0071900 157 0.068
nitrogen compound transport GO:0071705 271 0.067
positive regulation of mapk cascade GO:0043410 170 0.066
peptidyl amino acid modification GO:0018193 336 0.065
mapk cascade GO:0000165 281 0.063
diterpenoid metabolic process GO:0016101 24 0.063
regulation of protein processing GO:0070613 96 0.061
Mouse
negative regulation of molecular function GO:0044092 258 0.061
negative regulation of protein metabolic process GO:0051248 282 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.060
male gamete generation GO:0048232 285 0.060
regulation of kinase activity GO:0043549 249 0.060
activation of membrane attack complex GO:0001905 4 0.059
Mouse
macromolecule glycosylation GO:0043413 55 0.058
regulation of apoptotic signaling pathway GO:2001233 197 0.058
regulation of hormone levels GO:0010817 211 0.055
regulation of defense response GO:0031347 233 0.055
Mouse
response to organonitrogen compound GO:0010243 246 0.055
small molecule biosynthetic process GO:0044283 132 0.055
response to organic cyclic compound GO:0014070 198 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
anion transport GO:0006820 177 0.050
glycoprotein metabolic process GO:0009100 116 0.050
meiotic nuclear division GO:0007126 115 0.049
regulation of transferase activity GO:0051338 263 0.049
organic hydroxy compound metabolic process GO:1901615 203 0.048
isoprenoid metabolic process GO:0006720 29 0.048
macromolecule catabolic process GO:0009057 281 0.046
regulation of fibrinolysis GO:0051917 1 0.045
response to peptide GO:1901652 136 0.045
sterol metabolic process GO:0016125 58 0.044
blood coagulation GO:0007596 76 0.043
establishment of blood nerve barrier GO:0008065 3 0.041
ion transmembrane transport GO:0034220 361 0.041
oxidation reduction process GO:0055114 342 0.040
vitamin a metabolic process GO:0006776 2 0.040
glycosylation GO:0070085 62 0.039
negative regulation of protein processing GO:0010955 79 0.038
amide transport GO:0042886 138 0.036
peptide transport GO:0015833 133 0.036
coagulation GO:0050817 78 0.036
apoptotic signaling pathway GO:0097190 306 0.035
inflammatory response GO:0006954 244 0.035
Mouse
regulation of endopeptidase activity GO:0052548 89 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
cellular response to organonitrogen compound GO:0071417 145 0.035
hexose metabolic process GO:0019318 98 0.034
retinoid metabolic process GO:0001523 24 0.034
regulation of response to wounding GO:1903034 189 0.034
Mouse
response to peptide hormone GO:0043434 127 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
innate immune response GO:0045087 157 0.033
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.032
hemostasis GO:0007599 78 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
cell substrate adhesion GO:0031589 130 0.032
positive regulation of protein kinase activity GO:0045860 144 0.032
regulation of insulin receptor signaling pathway GO:0046626 21 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
alcohol metabolic process GO:0006066 116 0.031
organelle fission GO:0048285 170 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
regulation of anatomical structure size GO:0090066 178 0.030
regulation of hydrolase activity GO:0051336 246 0.030
regulation of peptidase activity GO:0052547 96 0.030
positive regulation of protein modification process GO:0031401 299 0.030
response to testosterone GO:0033574 3 0.030
insulin secretion GO:0030073 89 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
protein catabolic process GO:0030163 221 0.029
positive regulation of growth GO:0045927 104 0.028
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
regulation of cytokine production GO:0001817 266 0.028
glycerolipid metabolic process GO:0046486 122 0.028
monosaccharide metabolic process GO:0005996 106 0.028
multicellular organism growth GO:0035264 161 0.028
acylglycerol metabolic process GO:0006639 55 0.028
negative regulation of hydrolase activity GO:0051346 71 0.027
diterpenoid biosynthetic process GO:0016102 7 0.027
nuclear division GO:0000280 158 0.027
anion transmembrane transport GO:0098656 71 0.026
meiotic cell cycle GO:0051321 122 0.026
cation transmembrane transport GO:0098655 266 0.026
immune effector process GO:0002252 321 0.026
Mouse
sulfur compound metabolic process GO:0006790 100 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.025
actin cytoskeleton organization GO:0030036 220 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
cofactor metabolic process GO:0051186 80 0.025
negative regulation of protein maturation GO:1903318 79 0.025
wound healing GO:0042060 157 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of inflammatory response GO:0050727 147 0.025
Mouse
activation of immune response GO:0002253 138 0.024
Mouse
cellular response to hormone stimulus GO:0032870 150 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
cell growth GO:0016049 130 0.024
cellular protein catabolic process GO:0044257 155 0.024
protein glycosylation GO:0006486 55 0.024
aromatic compound catabolic process GO:0019439 286 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
sperm egg recognition GO:0035036 37 0.024
regulation of cholesterol metabolic process GO:0090181 14 0.024
anatomical structure homeostasis GO:0060249 145 0.023
exocytosis GO:0006887 121 0.023
activation of mapk activity GO:0000187 59 0.023
organic hydroxy compound transport GO:0015850 93 0.023
meiotic cell cycle process GO:1903046 77 0.023
cholesterol metabolic process GO:0008203 56 0.023
protein ubiquitination GO:0016567 171 0.023
spermatid differentiation GO:0048515 115 0.023
regulation of map kinase activity GO:0043405 120 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
positive regulation of kinase activity GO:0033674 155 0.022
cytokine production GO:0001816 319 0.022
regulation of complement activation GO:0030449 7 0.022
Mouse
regulation of glucose metabolic process GO:0010906 60 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
germ cell development GO:0007281 185 0.022
small molecule catabolic process GO:0044282 71 0.022
hexose biosynthetic process GO:0019319 39 0.022
cellular homeostasis GO:0019725 240 0.021
negative regulation of proteolysis GO:0045861 74 0.021
microtubule based process GO:0007017 236 0.021
fatty acid metabolic process GO:0006631 121 0.021
negative regulation of response to wounding GO:1903035 77 0.021
gland development GO:0048732 330 0.021
cell matrix adhesion GO:0007160 68 0.021
cellular response to peptide GO:1901653 92 0.021
regulation of secretion by cell GO:1903530 249 0.021
heterocycle catabolic process GO:0046700 280 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
acetylcholine secretion neurotransmission GO:0014055 2 0.020
membrane organization GO:0061024 245 0.020
organic acid biosynthetic process GO:0016053 86 0.020
regulation of hormone secretion GO:0046883 88 0.020
regulation of protein localization GO:0032880 231 0.020
terpenoid biosynthetic process GO:0016114 7 0.020
regulation of ketone biosynthetic process GO:0010566 2 0.020
phosphatidylinositol mediated signaling GO:0048015 41 0.020
positive regulation of protein activation cascade GO:2000259 2 0.020
Mouse
cellular chemical homeostasis GO:0055082 215 0.020
glucose metabolic process GO:0006006 92 0.020
rhythmic process GO:0048511 174 0.020
regulation of cell cycle GO:0051726 281 0.019
organic acid transport GO:0015849 101 0.019
negative regulation of endopeptidase activity GO:0010951 44 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
dna metabolic process GO:0006259 303 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
lipid localization GO:0010876 126 0.019
defense response to other organism GO:0098542 197 0.019
Mouse
activation of mapk activity involved in innate immune response GO:0035419 2 0.019
steroid metabolic process GO:0008202 119 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
hormone secretion GO:0046879 128 0.018
regulation of lipid biosynthetic process GO:0046890 54 0.018
cellular response to lipid GO:0071396 145 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
cell division GO:0051301 120 0.018
regulation of body fluid levels GO:0050878 162 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
regulation of blood vessel size GO:0050880 56 0.018
organic anion transport GO:0015711 137 0.018
organic hydroxy compound biosynthetic process GO:1901617 77 0.018
neurotransmitter transport GO:0006836 76 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
peptidyl serine modification GO:0018209 83 0.017
negative regulation of peptidase activity GO:0010466 46 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
positive regulation of cell death GO:0010942 224 0.017
neuron death GO:0070997 154 0.017
fertilization GO:0009566 127 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
cofactor transport GO:0051181 4 0.017
protein oligomerization GO:0051259 67 0.017
Mouse
extracellular structure organization GO:0043062 148 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
zymogen activation GO:0031638 41 0.017
homeostasis of number of cells GO:0048872 210 0.016
retina development in camera type eye GO:0060041 119 0.016
cell type specific apoptotic process GO:0097285 268 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
positive regulation of secretion GO:0051047 130 0.016
liver development GO:0001889 66 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
organ growth GO:0035265 117 0.016
negative regulation of lipid metabolic process GO:0045833 30 0.016
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.016
regulation of stress activated mapk cascade GO:0032872 69 0.016
regulation of cellular response to stress GO:0080135 159 0.016
regulation of cellular component size GO:0032535 121 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
positive regulation of complement activation GO:0045917 2 0.016
Mouse
cellular protein complex assembly GO:0043623 116 0.016
cation transport GO:0006812 399 0.015
regulation of multi organism process GO:0043900 111 0.015
positive regulation of protein kinase c activity GO:1900020 1 0.015
maintenance of location GO:0051235 89 0.015
positive regulation of proteolysis GO:0045862 85 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
regulation of ion transport GO:0043269 215 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
regulation of system process GO:0044057 200 0.015
female gamete generation GO:0007292 74 0.015
positive regulation of map kinase activity GO:0043406 84 0.015
regulation of protein catabolic process GO:0042176 108 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
retinoic acid metabolic process GO:0042573 12 0.015
cognition GO:0050890 149 0.015
sensory organ morphogenesis GO:0090596 242 0.015
regulation of secretion GO:0051046 274 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.015
chemotaxis GO:0006935 247 0.015
ras protein signal transduction GO:0007265 77 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
binding of sperm to zona pellucida GO:0007339 34 0.014
single organism cell adhesion GO:0098602 156 0.014
innate immune response in mucosa GO:0002227 3 0.014
synaptic transmission GO:0007268 329 0.014
nucleoside metabolic process GO:0009116 246 0.014
monosaccharide biosynthetic process GO:0046364 44 0.014
positive regulation of lipid metabolic process GO:0045834 40 0.014
response to insulin GO:0032868 100 0.014
protein n linked glycosylation GO:0006487 12 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of cell substrate adhesion GO:0010810 73 0.014
negative regulation of neuron death GO:1901215 98 0.014
regulation of cell adhesion GO:0030155 154 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
regulation of gluconeogenesis GO:0006111 30 0.014
camera type eye development GO:0043010 266 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
intracellular protein transport GO:0006886 204 0.014
lipid homeostasis GO:0055088 63 0.014
response to radiation GO:0009314 165 0.014
positive regulation of cytokine production GO:0001819 174 0.014
learning or memory GO:0007611 148 0.014
regulation of peptide transport GO:0090087 91 0.014
muscle cell differentiation GO:0042692 261 0.014
regulation of hemostasis GO:1900046 28 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
regulation of peptide secretion GO:0002791 77 0.014
carbohydrate biosynthetic process GO:0016051 74 0.013
regulation of cell growth GO:0001558 91 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
female gonad development GO:0008585 71 0.013
nucleoside catabolic process GO:0009164 206 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
neuron apoptotic process GO:0051402 142 0.013
insulin receptor signaling pathway GO:0008286 49 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
peptide hormone secretion GO:0030072 109 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
cholesterol transport GO:0030301 38 0.013
stress activated mapk cascade GO:0051403 80 0.013
cholesterol esterification GO:0034435 3 0.013
sterol transport GO:0015918 38 0.013
hormone metabolic process GO:0042445 86 0.013
response to light stimulus GO:0009416 135 0.013
regulation of carbohydrate biosynthetic process GO:0043255 40 0.013
methylation GO:0032259 134 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
gluconeogenesis GO:0006094 39 0.013
chromosome segregation GO:0007059 48 0.013
inositol lipid mediated signaling GO:0048017 41 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
glycerophospholipid metabolic process GO:0006650 71 0.012
purine containing compound metabolic process GO:0072521 311 0.012
endocytosis GO:0006897 168 0.012
nucleotide catabolic process GO:0009166 217 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of plasminogen activation GO:0010755 4 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.012
lipid transport GO:0006869 98 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
androgen biosynthetic process GO:0006702 4 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
vesicle localization GO:0051648 86 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of cell size GO:0008361 72 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
circulatory system process GO:0003013 197 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
single fertilization GO:0007338 82 0.012
establishment of organelle localization GO:0051656 122 0.012
glucose homeostasis GO:0042593 128 0.012
rho protein signal transduction GO:0007266 32 0.012
alcohol catabolic process GO:0046164 16 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
blood vessel morphogenesis GO:0048514 285 0.011
Mouse
regulation of blood coagulation GO:0030193 28 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
sensory perception GO:0007600 245 0.011
regulation of protein stability GO:0031647 52 0.011
positive regulation of plasminogen activation GO:0010756 2 0.011
t cell activation GO:0042110 289 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
inter male aggressive behavior GO:0002121 3 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of intestinal cholesterol absorption GO:0030300 4 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
negative regulation of carbohydrate metabolic process GO:0045912 19 0.011
organelle localization GO:0051640 179 0.011
negative regulation of nik nf kappab signaling GO:1901223 2 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
negative regulation of gluconeogenesis GO:0045721 9 0.011
skin development GO:0043588 220 0.011
response to nutrient levels GO:0031667 109 0.011
cellular response to cadmium ion GO:0071276 3 0.011
regulation of cell motility GO:2000145 236 0.011
negative regulation of cell cycle GO:0045786 123 0.011
mitotic cell cycle GO:0000278 195 0.011
organophosphate ester transport GO:0015748 28 0.011
hepaticobiliary system development GO:0061008 67 0.011
organophosphate catabolic process GO:0046434 232 0.011
negative regulation of coagulation GO:0050819 11 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
testosterone biosynthetic process GO:0061370 2 0.011
membrane depolarization GO:0051899 64 0.011
regulation of postsynaptic membrane potential GO:0060078 48 0.011
phospholipid metabolic process GO:0006644 87 0.011
regulation of cell projection organization GO:0031344 206 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
cellular aldehyde metabolic process GO:0006081 12 0.011
myosin filament organization GO:0031033 3 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
regulation of actin filament based process GO:0032970 99 0.010
negative regulation of fibrinolysis GO:0051918 1 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.010
nucleotide metabolic process GO:0009117 332 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
response to inorganic substance GO:0010035 96 0.010
angiogenesis GO:0001525 201 0.010
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
positive regulation of protein transport GO:0051222 93 0.010
cellular response to external stimulus GO:0071496 88 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
amino acid transport GO:0006865 61 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
cytoplasmic transport GO:0016482 234 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
mitochondrion organization GO:0007005 134 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
response to growth factor GO:0070848 198 0.010
neurotransmitter secretion GO:0007269 62 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010

C8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.042
inherited metabolic disorder DOID:655 0 0.028
nervous system disease DOID:863 0 0.020
disease of anatomical entity DOID:7 0 0.020
disease of cellular proliferation DOID:14566 0 0.013