|
|
cytokine production
|
GO:0001816 |
319 |
0.680
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.656
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.502
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.488
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.448
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.446
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.443
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.416
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.410
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.388
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.379
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.377
|
Mouse Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.357
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.353
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.352
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.350
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.336
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.306
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.289
|
Mouse Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.287
|
Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.280
|
Mouse Worm Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.267
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
21 |
0.245
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.242
|
Mouse Worm Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.241
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.232
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.227
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.218
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.207
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.200
|
Fly |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.199
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.196
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.191
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.188
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.185
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.176
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.174
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.170
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.169
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.165
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.164
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.161
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.160
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.157
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.151
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.148
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.144
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.142
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.140
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.135
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.134
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.133
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.131
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.130
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.130
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.128
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.128
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.128
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.127
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.126
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.125
|
Mouse Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.121
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.120
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.119
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.117
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.116
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.112
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.111
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.108
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.106
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.104
|
Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.102
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.102
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.100
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.099
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.098
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.097
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.097
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.097
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.094
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.094
|
Mouse |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.091
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.089
|
Fly |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.089
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.088
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.088
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.086
|
Mouse |
|
|
cartilage development
|
GO:0051216 |
140 |
0.085
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.085
|
Mouse Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.085
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.084
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.077
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.076
|
Mouse |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.076
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.076
|
Mouse Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.075
|
Mouse Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.075
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.075
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.075
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.075
|
Fly |
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.075
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.074
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.074
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.074
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.074
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.074
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.073
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.073
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.073
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.073
|
Mouse Fly |
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.073
|
Fly |
|
|
regulation of macrophage migration inhibitory factor signaling pathway
|
GO:2000446 |
1 |
0.072
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.072
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.072
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.071
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.071
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.071
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.071
|
Mouse Fly |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.070
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.068
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.068
|
Fly |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.067
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.065
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.065
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.064
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.064
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.064
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.064
|
Mouse Fly |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.063
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.063
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.063
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.059
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.058
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.058
|
Mouse |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.057
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.057
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.056
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.055
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.055
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.055
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.054
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.054
|
Mouse Fly |
|
|
protein import
|
GO:0017038 |
101 |
0.054
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.053
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.053
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.053
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.053
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.052
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.052
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.052
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.052
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.052
|
Mouse Fly |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.052
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.051
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.051
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.051
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.050
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.050
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.049
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.049
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.049
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.049
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.048
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.048
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.048
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.047
|
Fly |
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.046
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.046
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.046
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.045
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.045
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.045
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.045
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.045
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.045
|
Mouse Fly |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.045
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.045
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.045
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.045
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.044
|
|
|
|
cellular response to interferon alpha
|
GO:0035457 |
4 |
0.044
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.043
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.042
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.042
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.042
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.042
|
Worm |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.042
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.042
|
|
|
|
response to interferon beta
|
GO:0035456 |
22 |
0.041
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.041
|
Mouse Fly |
|
|
anion transport
|
GO:0006820 |
177 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.041
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.041
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.041
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.040
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.040
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.040
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.040
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.039
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.039
|
Fly |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.039
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.039
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.039
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.038
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.038
|
Mouse Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.038
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.038
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.037
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.037
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.037
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.037
|
Mouse |
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.037
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.036
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.036
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.036
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.036
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
5 |
0.036
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.036
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.036
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.035
|
|
|
|
macrophage migration inhibitory factor signaling pathway
|
GO:0035691 |
2 |
0.035
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.035
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.035
|
Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.035
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.034
|
Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.034
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.034
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.034
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.034
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.034
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.034
|
Mouse Worm |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.034
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.032
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.032
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.032
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.032
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.032
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.032
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.032
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.032
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.032
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.031
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.031
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.031
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.031
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.031
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.031
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.031
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.031
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.030
|
Worm |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.030
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.030
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.030
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.030
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.030
|
|
|
|
negative regulation of odontogenesis
|
GO:0042483 |
3 |
0.029
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.029
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.029
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.029
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.029
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.029
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.029
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.029
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.029
|
Worm |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.028
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.028
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.028
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.028
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.028
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.028
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.028
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.028
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.028
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.028
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.028
|
Fly |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.028
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.027
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.027
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.027
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.027
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.027
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.027
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.027
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.027
|
Mouse |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.026
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.026
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.026
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
21 |
0.026
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.026
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.026
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.026
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.026
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.026
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.026
|
Mouse Fly |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.026
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.025
|
Mouse Fly |
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.025
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.025
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.025
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.025
|
|
|
|
regulation of complement activation
|
GO:0030449 |
7 |
0.025
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.025
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.025
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.025
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.025
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.025
|
Mouse |
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.025
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.025
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.025
|
Mouse |
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.025
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.024
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.024
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.024
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.024
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.024
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.024
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.024
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.024
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.024
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.024
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.024
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.024
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.023
|
Mouse |
|
|
response to amino acid
|
GO:0043200 |
37 |
0.023
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.023
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.023
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.023
|
Mouse |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.023
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.023
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.023
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.023
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.023
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.023
|
Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.023
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.023
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.022
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.022
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.022
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.022
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.022
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.022
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.022
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.022
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.022
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.022
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.022
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.021
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.021
|
Mouse Fly |
|
|
interleukin 17 production
|
GO:0032620 |
11 |
0.021
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.021
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.021
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.021
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.021
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.021
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.021
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.021
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.021
|
|
|
|
regulation of tooth mineralization
|
GO:0070170 |
2 |
0.021
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.021
|
Worm |
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.021
|
Mouse |
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.021
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.021
|
|
|
|
negative regulation of complement activation
|
GO:0045916 |
3 |
0.020
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.020
|
Mouse |
|
|
negative regulation of interferon alpha production
|
GO:0032687 |
1 |
0.020
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.020
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.020
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.020
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.020
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.020
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.020
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.020
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.020
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.020
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.020
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.020
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.020
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.020
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.020
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.020
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.020
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.020
|
Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.020
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.020
|
Mouse |
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.020
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.019
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.019
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.019
|
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
3 |
0.019
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.019
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.019
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
23 |
0.019
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.019
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.019
|
Fly |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.019
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.019
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.019
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.019
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.019
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.019
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.019
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.019
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.019
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.019
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.019
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.019
|
Mouse |
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.018
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.018
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.018
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
3 |
0.018
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.018
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.018
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.018
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.018
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.018
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.018
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.018
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.018
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.018
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.018
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.018
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.018
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.017
|
|
|
|
hematopoietic stem cell proliferation
|
GO:0071425 |
13 |
0.017
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.017
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.017
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.017
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.017
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.017
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.017
|
|
|
|
acute phase response
|
GO:0006953 |
10 |
0.017
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.017
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.017
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.017
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.017
|
|
|
|
viral transcription
|
GO:0019083 |
3 |
0.017
|
|
|
|
regulation of hematopoietic stem cell proliferation
|
GO:1902033 |
3 |
0.017
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.017
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.017
|
Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.017
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.017
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.017
|
Mouse |
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.017
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.017
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.017
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.016
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.016
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.016
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.016
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.016
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.016
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.016
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.016
|
Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.016
|
Mouse |
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.016
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.016
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.016
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.016
|
Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.016
|
|
|
|
regulation of interleukin 1 alpha production
|
GO:0032650 |
4 |
0.016
|
Mouse |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.016
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.016
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.016
|
Mouse |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.016
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.016
|
Worm |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.016
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.016
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.016
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.016
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.016
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.016
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.016
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.015
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.015
|
Mouse |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.015
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.015
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.015
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.015
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.015
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.015
|
Mouse |
|
|
cellularization
|
GO:0007349 |
1 |
0.015
|
Fly |
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.015
|
|
