Mus musculus

0 known processes

Casp14

caspase 14

(Aliases: MGC123949,MGC123948,MICE,mini-ICE)

Casp14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of secretion GO:0051046 274 0.670
Mouse
regulation of body fluid levels GO:0050878 162 0.290
regulation of cellular amine metabolic process GO:0033238 20 0.273
positive regulation of cellular amine metabolic process GO:0033240 5 0.250
regulation of cellular amino acid metabolic process GO:0006521 5 0.247
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.225
gland development GO:0048732 330 0.218
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.215
regulation of cell migration GO:0030334 219 0.205
sensory perception GO:0007600 245 0.205
Mouse
cell maturation GO:0048469 127 0.200
Fly
negative regulation of cell proliferation GO:0008285 296 0.184
Mouse Fly
cellular amine metabolic process GO:0044106 44 0.172
extrinsic apoptotic signaling pathway GO:0097191 126 0.164
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.164
nucleotide biosynthetic process GO:0009165 78 0.158
purine nucleotide biosynthetic process GO:0006164 65 0.156
epithelial cell proliferation GO:0050673 174 0.153
regulation of cell motility GO:2000145 236 0.143
negative regulation of immune system process GO:0002683 209 0.130
Mouse
skin development GO:0043588 220 0.128
Mouse
aromatic compound catabolic process GO:0019439 286 0.127
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.127
amine metabolic process GO:0009308 45 0.125
vitamin d biosynthetic process GO:0042368 3 0.124
wound healing GO:0042060 157 0.123
regulation of secretion by cell GO:1903530 249 0.122
Mouse
positive regulation of protein modification process GO:0031401 299 0.121
cellular ketone metabolic process GO:0042180 84 0.118
regulation of keratinocyte differentiation GO:0045616 11 0.115
nucleotide metabolic process GO:0009117 332 0.113
nucleobase containing small molecule metabolic process GO:0055086 352 0.111
nucleoside phosphate metabolic process GO:0006753 338 0.111
t cell activation GO:0042110 289 0.107
Mouse
regulation of saliva secretion GO:0046877 2 0.107
blood vessel morphogenesis GO:0048514 285 0.106
Mouse
cell type specific apoptotic process GO:0097285 268 0.104
Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.101
epithelial cell development GO:0002064 159 0.098
developmental maturation GO:0021700 193 0.097
Fly
establishment of skin barrier GO:0061436 14 0.095
response to organic cyclic compound GO:0014070 198 0.093
Mouse
linoleic acid metabolic process GO:0043651 6 0.091
negative regulation of phosphate metabolic process GO:0045936 184 0.091
Mouse
leukocyte chemotaxis GO:0030595 69 0.091
intermediate filament cytoskeleton organization GO:0045104 26 0.090
regulation of epithelial cell proliferation GO:0050678 141 0.090
peptidyl tyrosine phosphorylation GO:0018108 143 0.089
hematopoietic progenitor cell differentiation GO:0002244 143 0.086
axonogenesis GO:0007409 274 0.085
regulation of transferase activity GO:0051338 263 0.085
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.083
digestive system development GO:0055123 200 0.083
regulation of t cell activation GO:0050863 170 0.083
Mouse
positive regulation of cell migration GO:0030335 109 0.082
cell chemotaxis GO:0060326 81 0.079
peptidyl tyrosine modification GO:0018212 145 0.078
purine nucleotide metabolic process GO:0006163 302 0.077
regulation of water loss via skin GO:0033561 16 0.076
regulation of glial cell differentiation GO:0045685 41 0.074
cellular response to cytokine stimulus GO:0071345 189 0.073
blood circulation GO:0008015 195 0.071
negative regulation of secretion GO:0051048 61 0.070
keratinocyte differentiation GO:0030216 48 0.070
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.070
maintenance of location GO:0051235 89 0.069
urogenital system development GO:0001655 261 0.069
regulation of inflammatory response GO:0050727 147 0.068
Mouse
forebrain development GO:0030900 302 0.065
response to organonitrogen compound GO:0010243 246 0.065
Mouse
cellular homeostasis GO:0019725 240 0.064
heterocycle catabolic process GO:0046700 280 0.064
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.064
regulation of defense response GO:0031347 233 0.063
Mouse Fly
multicellular organismal homeostasis GO:0048871 164 0.063
cellular nitrogen compound catabolic process GO:0044270 280 0.062
Mouse
hormone secretion GO:0046879 128 0.061
positive regulation of secretion GO:0051047 130 0.061
Mouse
oligodendrocyte differentiation GO:0048709 53 0.061
cellular response to lipid GO:0071396 145 0.060
Mouse
regulation of response to wounding GO:1903034 189 0.060
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.059
regulation of lymphocyte activation GO:0051249 240 0.059
Mouse
positive regulation of mapk cascade GO:0043410 170 0.059
digestive tract development GO:0048565 190 0.059
axon guidance GO:0007411 141 0.058
defense response to other organism GO:0098542 197 0.058
Fly
inorganic ion transmembrane transport GO:0098660 234 0.058
vitamin metabolic process GO:0006766 23 0.058
cellular potassium ion transport GO:0071804 43 0.057
unsaturated fatty acid metabolic process GO:0033559 31 0.057
cellular amino acid metabolic process GO:0006520 103 0.057
response to stilbenoid GO:0035634 22 0.057
positive regulation of lipid transport GO:0032370 22 0.057
leukocyte differentiation GO:0002521 342 0.056
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.056
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.056
endocytosis GO:0006897 168 0.055
Worm
regulation of gliogenesis GO:0014013 50 0.055
metal ion homeostasis GO:0055065 189 0.054
cellular ion homeostasis GO:0006873 165 0.054
positive regulation of cell death GO:0010942 224 0.054
Mouse Fly
chemotaxis GO:0006935 247 0.053
negative regulation of multi organism process GO:0043901 68 0.053
regulation of anatomical structure size GO:0090066 178 0.053
regulation of mapk cascade GO:0043408 248 0.053
intermediate filament organization GO:0045109 15 0.052
organic hydroxy compound metabolic process GO:1901615 203 0.052
Fly
glial cell differentiation GO:0010001 131 0.051
neuron migration GO:0001764 122 0.051
stem cell differentiation GO:0048863 268 0.051
immune effector process GO:0002252 321 0.051
Fly
locomotory behavior GO:0007626 195 0.051
positive regulation of nervous system development GO:0051962 221 0.050
neuron projection guidance GO:0097485 141 0.050
cellular calcium ion homeostasis GO:0006874 119 0.050
epidermis development GO:0008544 187 0.050
Mouse
t cell proliferation GO:0042098 120 0.048
Mouse
forebrain generation of neurons GO:0021872 63 0.048
negative regulation of cell activation GO:0050866 111 0.048
Mouse
regulation of membrane potential GO:0042391 192 0.048
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.048
apoptotic signaling pathway GO:0097190 306 0.047
Mouse Fly
protein autophosphorylation GO:0046777 61 0.047
regulation of ion transport GO:0043269 215 0.046
innate immune response GO:0045087 157 0.046
Fly
tissue remodeling GO:0048771 102 0.046
adaptive immune response GO:0002250 155 0.045
regulation of kinase activity GO:0043549 249 0.045
Mouse
regulation of protein localization GO:0032880 231 0.045
Mouse
intermediate filament based process GO:0045103 27 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
angiogenesis GO:0001525 201 0.044
Mouse
organophosphate biosynthetic process GO:0090407 122 0.044
negative regulation of molecular function GO:0044092 258 0.044
Mouse
cellular alcohol metabolic process GO:0044107 3 0.044
potassium ion transmembrane transport GO:0071805 43 0.044
positive regulation of t cell activation GO:0050870 101 0.043
cyclic purine nucleotide metabolic process GO:0052652 43 0.043
gabaergic neuron differentiation GO:0097154 11 0.043
cation homeostasis GO:0055080 212 0.043
sensory organ morphogenesis GO:0090596 242 0.043
Fly
carbohydrate transport GO:0008643 62 0.042
regulation of epidermal cell differentiation GO:0045604 21 0.042
leukocyte mediated immunity GO:0002443 174 0.042
anatomical structure homeostasis GO:0060249 145 0.042
regulation of nucleotide metabolic process GO:0006140 169 0.041
macromolecule catabolic process GO:0009057 281 0.041
Mouse Worm
cell adhesion GO:0007155 329 0.041
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.041
regulation of cell growth GO:0001558 91 0.041
positive regulation of leukocyte differentiation GO:1902107 86 0.040
sensory perception of mechanical stimulus GO:0050954 107 0.040
Mouse
regulation of t cell differentiation GO:0045580 83 0.040
positive regulation of cell motility GO:2000147 116 0.040
regulation of vesicle mediated transport GO:0060627 139 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
regulation of metal ion transport GO:0010959 106 0.040
defense response to bacterium GO:0042742 119 0.040
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.040
Mouse
regulation of hormone levels GO:0010817 211 0.039
carbohydrate metabolic process GO:0005975 230 0.039
gliogenesis GO:0042063 141 0.039
somatostatin receptor signaling pathway GO:0038169 2 0.039
ribose phosphate biosynthetic process GO:0046390 59 0.038
positive regulation of lymphocyte activation GO:0051251 140 0.038
ribonucleotide biosynthetic process GO:0009260 59 0.038
negative regulation of secretion by cell GO:1903531 54 0.038
positive regulation of cell development GO:0010720 237 0.038
Fly
developmental growth involved in morphogenesis GO:0060560 138 0.038
regulation of hydrolase activity GO:0051336 246 0.037
Mouse Fly
cyclic nucleotide biosynthetic process GO:0009190 44 0.037
myeloid leukocyte migration GO:0097529 57 0.037
engulfment of apoptotic cell GO:0043652 3 0.037
Worm
positive regulation of steroid hormone secretion GO:2000833 2 0.037
alpha beta t cell activation GO:0046631 91 0.037
calcitriol biosynthetic process from calciol GO:0036378 3 0.036
regulation of purine nucleotide metabolic process GO:1900542 169 0.036
arachidonic acid metabolic process GO:0019369 14 0.036
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.036
respiratory system development GO:0060541 190 0.036
peptide hormone secretion GO:0030072 109 0.036
olfactory learning GO:0008355 2 0.035
leukocyte migration GO:0050900 124 0.035
lymphocyte differentiation GO:0030098 242 0.035
multicellular organismal signaling GO:0035637 91 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
Mouse
muscle cell differentiation GO:0042692 261 0.035
muscle tissue development GO:0060537 308 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
Mouse
mapk cascade GO:0000165 281 0.034
nucleoside phosphate biosynthetic process GO:1901293 79 0.034
divalent inorganic cation transport GO:0072511 178 0.033
lymphocyte proliferation GO:0046651 164 0.033
Mouse
cytokine metabolic process GO:0042107 71 0.033
regulation of system process GO:0044057 200 0.032
cell fate commitment GO:0045165 210 0.032
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.032
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.032
regulation of cytokine production GO:0001817 266 0.032
Mouse
peptidyl amino acid modification GO:0018193 336 0.032
regulation of thyroid hormone generation GO:2000609 4 0.031
naphthalene containing compound metabolic process GO:0090420 1 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
regulation of protein transport GO:0051223 163 0.031
Mouse
lipid biosynthetic process GO:0008610 179 0.031
protein maturation GO:0051604 176 0.031
Mouse Worm Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.031
porphyrin containing compound metabolic process GO:0006778 22 0.031
purine containing compound catabolic process GO:0072523 213 0.030
protein processing GO:0016485 163 0.030
Mouse Worm Fly
purine ribonucleotide metabolic process GO:0009150 290 0.030
transmission of nerve impulse GO:0019226 76 0.030
leukocyte homeostasis GO:0001776 79 0.030
Mouse
lipid localization GO:0010876 126 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
Mouse Fly
regulation of translation GO:0006417 71 0.030
glial cell development GO:0021782 54 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of exocytosis GO:0017157 61 0.029
leukocyte proliferation GO:0070661 172 0.029
Mouse
dendritic cell differentiation GO:0097028 26 0.029
tissue regeneration GO:0042246 22 0.029
regulation of cellular component size GO:0032535 121 0.028
small molecule biosynthetic process GO:0044283 132 0.028
response to acid chemical GO:0001101 111 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
protein localization to organelle GO:0033365 185 0.028
striated muscle tissue development GO:0014706 293 0.028
lymphocyte apoptotic process GO:0070227 54 0.028
Mouse
detection of stimulus GO:0051606 84 0.028
myeloid cell differentiation GO:0030099 233 0.028
Mouse
compound eye development GO:0048749 1 0.028
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.028
sensory perception of sound GO:0007605 97 0.028
Mouse
regulation of neuron differentiation GO:0045664 281 0.027
erk1 and erk2 cascade GO:0070371 77 0.027
neuronal action potential GO:0019228 54 0.027
positive regulation of immune effector process GO:0002699 107 0.027
Fly
regulation of protein catabolic process GO:0042176 108 0.027
regulation of hormone secretion GO:0046883 88 0.027
positive regulation of vasoconstriction GO:0045907 4 0.026
negative regulation of interleukin 13 production GO:0032696 2 0.026
regulation of oligodendrocyte differentiation GO:0048713 23 0.026
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.026
response to inorganic substance GO:0010035 96 0.026
positive regulation of response to wounding GO:1903036 66 0.026
stem cell development GO:0048864 219 0.026
translation GO:0006412 93 0.026
production of molecular mediator of immune response GO:0002440 103 0.026
Fly
cation transmembrane transport GO:0098655 266 0.026
nitrogen compound transport GO:0071705 271 0.026
skeletal system development GO:0001501 356 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.025
cellular chemical homeostasis GO:0055082 215 0.025
vitamin d3 metabolic process GO:0070640 3 0.025
regulation of protein kinase activity GO:0045859 232 0.025
Mouse
muscle cell development GO:0055001 133 0.025
limb development GO:0060173 166 0.025
sequestering of metal ion GO:0051238 19 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
Mouse
vascular process in circulatory system GO:0003018 62 0.024
response to alcohol GO:0097305 48 0.024
Mouse
intestinal epithelial cell differentiation GO:0060575 14 0.024
viral process GO:0016032 41 0.024
tissue homeostasis GO:0001894 115 0.024
positive regulation of cell activation GO:0050867 158 0.024
regulation of cell activation GO:0050865 289 0.024
Mouse
morphogenesis of a branching structure GO:0001763 203 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.024
regulation of epidermis development GO:0045682 33 0.024
sensory perception of pain GO:0019233 47 0.023
protein secretion GO:0009306 111 0.023
Mouse
fatty acid derivative metabolic process GO:1901568 33 0.023
protein catabolic process GO:0030163 221 0.023
Worm
reactive oxygen species metabolic process GO:0072593 84 0.023
neutrophil chemotaxis GO:0030593 36 0.023
regulation of receptor activity GO:0010469 41 0.023
cerebral cortex neuron differentiation GO:0021895 19 0.023
regulation of lymphocyte apoptotic process GO:0070228 41 0.023
Mouse
glycosyl compound metabolic process GO:1901657 246 0.023
cation transport GO:0006812 399 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
monocarboxylic acid biosynthetic process GO:0072330 61 0.022
g protein coupled receptor internalization GO:0002031 3 0.022
second messenger mediated signaling GO:0019932 73 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
Mouse Fly
signal transduction in absence of ligand GO:0038034 55 0.022
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.022
purine ribonucleotide biosynthetic process GO:0009152 59 0.022
negative regulation of homeostatic process GO:0032845 71 0.022
cellular metal ion homeostasis GO:0006875 151 0.021
regulation of cytokine secretion GO:0050707 61 0.021
Mouse
organ growth GO:0035265 117 0.021
lymphocyte activation involved in immune response GO:0002285 93 0.021
ameboidal type cell migration GO:0001667 128 0.021
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.021
positive regulation of t cell differentiation GO:0045582 52 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
somatostatin signaling pathway GO:0038170 2 0.021
glycoprotein metabolic process GO:0009100 116 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
Fly
keratinization GO:0031424 9 0.021
myeloid cell homeostasis GO:0002262 114 0.021
oxidation reduction process GO:0055114 342 0.021
granulocyte migration GO:0097530 43 0.021
associative learning GO:0008306 61 0.020
regulation of fat cell proliferation GO:0070344 4 0.020
positive regulation of t cell costimulation GO:2000525 2 0.020
receptor mediated endocytosis GO:0006898 51 0.020
monosaccharide transport GO:0015749 58 0.020
digestion GO:0007586 40 0.020
regulation of renal sodium excretion GO:0035813 3 0.020
positive regulation of organelle organization GO:0010638 128 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
negative regulation of cell migration GO:0030336 59 0.020
negative regulation of lymphocyte activation GO:0051250 91 0.020
Mouse
skin morphogenesis GO:0043589 38 0.020
glossopharyngeal nerve morphogenesis GO:0021615 4 0.020
fat cell differentiation GO:0045444 160 0.020
pallium development GO:0021543 120 0.020
hexose transport GO:0008645 56 0.020
endomembrane system organization GO:0010256 147 0.020
skeletal system morphogenesis GO:0048705 203 0.020
syncytium formation GO:0006949 43 0.020
heart morphogenesis GO:0003007 178 0.020
sequestering of calcium ion GO:0051208 18 0.019
negative regulation of growth GO:0045926 99 0.019
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.019
mast cell proliferation GO:0070662 4 0.019
membrane organization GO:0061024 245 0.019
Worm
prevention of polyspermy GO:0060468 4 0.019
regulation of chemotaxis GO:0050920 53 0.019
hematopoietic stem cell migration GO:0035701 1 0.019
divalent metal ion transport GO:0070838 172 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.019
negative regulation of epithelial cell proliferation GO:0050680 64 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
male gamete generation GO:0048232 285 0.019
Fly
positive regulation of glial cell differentiation GO:0045687 21 0.019
regulation of astrocyte differentiation GO:0048710 20 0.019
metanephric dct cell differentiation GO:0072240 3 0.018
organic acid biosynthetic process GO:0016053 86 0.018
secondary alcohol metabolic process GO:1902652 3 0.018
negative regulation of muscle cell differentiation GO:0051148 33 0.018
blastocyst development GO:0001824 80 0.018
regulation of cell size GO:0008361 72 0.018
positive regulation of glial cell proliferation GO:0060252 4 0.018
cellular alcohol biosynthetic process GO:0044108 3 0.018
positive regulation of chemotaxis GO:0050921 38 0.018
glucose transport GO:0015758 56 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
Mouse
peptide transport GO:0015833 133 0.018
nuclear transport GO:0051169 139 0.018
regulation of calcium ion transport GO:0051924 69 0.018
negative regulation of t cell activation GO:0050868 65 0.018
Mouse
fertilization GO:0009566 127 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.018
alpha beta t cell differentiation GO:0046632 69 0.018
regulation of engulfment of apoptotic cell GO:1901074 2 0.018
regulation of neuron death GO:1901214 134 0.018
Mouse
regulation of brown fat cell proliferation GO:0070347 1 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
Mouse
regulation of lipid transport GO:0032368 36 0.017
regulation of organelle organization GO:0033043 289 0.017
neuron apoptotic process GO:0051402 142 0.017
Mouse
telencephalon development GO:0021537 186 0.017
action potential GO:0001508 78 0.017
nucleotide catabolic process GO:0009166 217 0.017
tube formation GO:0035148 140 0.017
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.017
cell recognition GO:0008037 83 0.017
steroid metabolic process GO:0008202 119 0.017
cellular response to cadmium ion GO:0071276 3 0.017
organophosphate catabolic process GO:0046434 232 0.017
transmembrane transport GO:0055085 412 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
insulin secretion GO:0030073 89 0.016
estrogen secretion GO:0035937 1 0.016
hair follicle morphogenesis GO:0031069 29 0.016
calcium ion homeostasis GO:0055074 127 0.016
regulation of feeding behavior GO:0060259 3 0.016
amide transport GO:0042886 138 0.016
positive regulation of neutrophil migration GO:1902624 12 0.016
columnar cuboidal epithelial cell development GO:0002066 29 0.016
circulatory system process GO:0003013 197 0.016
response to iron ion GO:0010039 4 0.016
cofactor metabolic process GO:0051186 80 0.016
steroid biosynthetic process GO:0006694 47 0.016
positive regulation of gliogenesis GO:0014015 27 0.016
intracellular protein transport GO:0006886 204 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
response to drug GO:0042493 75 0.016
forebrain cell migration GO:0021885 58 0.016
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.016
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.016
cellular response to inorganic substance GO:0071241 37 0.016
metanephric loop of henle development GO:0072236 4 0.016
response to phenylpropanoid GO:0080184 22 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
Mouse Fly
t cell differentiation GO:0030217 174 0.016
striated muscle cell development GO:0055002 125 0.015
positive regulation of interleukin 6 production GO:0032755 37 0.015
negative regulation of hydrolase activity GO:0051346 71 0.015
regulation of skeletal muscle fiber development GO:0048742 36 0.015
regulation of vasculature development GO:1901342 88 0.015
epidermis morphogenesis GO:0048730 33 0.015
regulation of cell adhesion GO:0030155 154 0.015
metanephric ascending thin limb development GO:0072218 2 0.015
actin cytoskeleton organization GO:0030036 220 0.015
negative regulation of defense response GO:0031348 77 0.015
ras protein signal transduction GO:0007265 77 0.015
interspecies interaction between organisms GO:0044419 83 0.015
positive regulation of angiogenesis GO:0045766 46 0.015
response to lipopolysaccharide GO:0032496 128 0.015
Mouse
germ cell development GO:0007281 185 0.015
Fly
axon ensheathment GO:0008366 76 0.015
myotube differentiation GO:0014902 105 0.015
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.015
intracellular receptor signaling pathway GO:0030522 74 0.015
regulation of mast cell proliferation GO:0070666 4 0.015
naphthalene metabolic process GO:0018931 1 0.015
regulation of estrogen secretion GO:2000861 1 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
myoblast differentiation GO:0045445 52 0.015
sulfur compound metabolic process GO:0006790 100 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
regulation of myotube differentiation GO:0010830 62 0.014
positive regulation of keratinocyte differentiation GO:0045618 3 0.014
regulation of heart rate GO:0002027 36 0.014
b cell activation GO:0042113 161 0.014
Mouse
peptide secretion GO:0002790 114 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
defense response to gram positive bacterium GO:0050830 50 0.014
neutrophil migration GO:1990266 37 0.014
homeostasis of number of cells GO:0048872 210 0.014
Mouse
glycosyl compound catabolic process GO:1901658 206 0.014
spermatogenesis GO:0007283 284 0.014
Fly
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.014
type 2 immune response GO:0042092 23 0.014
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.014
t cell extravasation GO:0072683 4 0.014
brown fat cell proliferation GO:0070342 1 0.014
regulation of protein complex assembly GO:0043254 83 0.014
ceramide biosynthetic process GO:0046513 20 0.014
positive regulation of kinase activity GO:0033674 155 0.014
exocytosis GO:0006887 121 0.014
neural precursor cell proliferation GO:0061351 121 0.014
leukocyte apoptotic process GO:0071887 71 0.014
Mouse
inner ear receptor cell development GO:0060119 39 0.014
regulation of cell projection assembly GO:0060491 38 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
calcium ion transport GO:0006816 159 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
negative regulation of interleukin 5 production GO:0032714 4 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of immunological synapse formation GO:2000520 2 0.013
gastric acid secretion GO:0001696 6 0.013
monovalent inorganic cation homeostasis GO:0055067 33 0.013
neuron death GO:0070997 154 0.013
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
response to steroid hormone GO:0048545 56 0.013
Mouse
appendage development GO:0048736 166 0.013
regulation of transmembrane transport GO:0034762 128 0.013
myeloid cell activation involved in immune response GO:0002275 34 0.013
regulation of monocyte chemotaxis GO:0090025 3 0.013
positive regulation of translation GO:0045727 19 0.013
negative regulation of glial cell differentiation GO:0045686 21 0.013
regulation of ion homeostasis GO:2000021 64 0.013
long chain fatty acid metabolic process GO:0001676 26 0.013
negative regulation of gliogenesis GO:0014014 23 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
negative regulation of nervous system development GO:0051961 156 0.013
fat cell proliferation GO:0070341 4 0.013
hepatocyte apoptotic process GO:0097284 11 0.013
Mouse
tachykinin receptor signaling pathway GO:0007217 1 0.013
acid secretion GO:0046717 33 0.013
cellular response to metal ion GO:0071248 31 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.013
subpallium neuron fate commitment GO:0060163 2 0.013
granulocyte chemotaxis GO:0071621 39 0.013
bone development GO:0060348 120 0.013
regulation of blood pressure GO:0008217 93 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
defecation GO:0030421 1 0.012
forebrain neuron differentiation GO:0021879 52 0.012

Casp14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
mouth disease DOID:403 0 0.014
disease of anatomical entity DOID:7 0 0.014
gastrointestinal system disease DOID:77 0 0.014