|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.999
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.998
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.998
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.996
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.995
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.995
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.995
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.994
|
Fly |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.993
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.992
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.992
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.992
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.986
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.986
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.986
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.984
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.984
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.984
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.983
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.982
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.982
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.978
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.978
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.977
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.976
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.973
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.971
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.969
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.963
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.963
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.961
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.959
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.958
|
Mouse |
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.954
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.952
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.948
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.947
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.947
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.945
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.943
|
Fly |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.942
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.939
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.938
|
Mouse |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.936
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.936
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.933
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.932
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.931
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.929
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.929
|
Mouse |
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
3 |
0.927
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.924
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.922
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.920
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.920
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.919
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.919
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.919
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.918
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.917
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.916
|
Fly |
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.906
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.902
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.900
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.900
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.900
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.899
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.895
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.893
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.883
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.883
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.883
|
Fly |
|
|
response to insulin
|
GO:0032868 |
100 |
0.882
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.881
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.876
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.875
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
7 |
0.874
|
Fly |
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.874
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.872
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.872
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.870
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.869
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.868
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.867
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.857
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.856
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.854
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.854
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.852
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.850
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.849
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.846
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.845
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.844
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.839
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.835
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.834
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.834
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.833
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.833
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.830
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.828
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.828
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.825
|
Fly |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.823
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.823
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.822
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.822
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.821
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.821
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.820
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.817
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.813
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.811
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.810
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.803
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.802
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.800
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.798
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.797
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.795
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.793
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.792
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.789
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.789
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.776
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.775
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.774
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.774
|
Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.774
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.770
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.762
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.756
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.755
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.753
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.753
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.750
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.747
|
Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.737
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.736
|
|
|
|
negative regulation of receptor activity
|
GO:2000272 |
5 |
0.735
|
Fly |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.734
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.731
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.731
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
14 |
0.730
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.730
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.729
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.729
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.728
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.725
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.724
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.723
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.719
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.717
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.712
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.709
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.707
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.700
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.698
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.695
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.694
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.693
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.693
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.691
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.691
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.690
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.689
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.685
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.683
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.674
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.672
|
Fly |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.668
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.668
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.666
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.658
|
Mouse |
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.651
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.649
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.646
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.643
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.639
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.635
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.632
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.630
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.628
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.627
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.620
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.619
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.619
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.619
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.618
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.617
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.617
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
7 |
0.614
|
Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.611
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.610
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.609
|
Fly |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.607
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.603
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.596
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.594
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.593
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.590
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.590
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.580
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.577
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.575
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.566
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.564
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.563
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.557
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.555
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.555
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.553
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.552
|
Fly |
|
|
gonad development
|
GO:0008406 |
141 |
0.550
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.546
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.544
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.543
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.543
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.542
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.542
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.540
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.538
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.537
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.537
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.533
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.532
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.531
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.529
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.525
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.521
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.520
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.515
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.511
|
Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.511
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.510
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.507
|
Fly |
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.506
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.501
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.500
|
Fly |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.499
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.499
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.496
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
3 |
0.496
|
Fly |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.494
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.492
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.490
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.485
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.485
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.485
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
6 |
0.483
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.481
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.478
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.477
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.475
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.474
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.466
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.466
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.463
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.463
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.461
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.460
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.459
|
Fly |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.455
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.454
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.452
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.452
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.450
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.449
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.448
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.446
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.440
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.439
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.438
|
Fly |
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.437
|
Mouse |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.433
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.429
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.425
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.424
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.424
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.422
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.422
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.421
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.421
|
Fly |
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.417
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.414
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.412
|
Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.407
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.407
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
0.404
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.403
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.402
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.402
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.402
|
Fly |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.401
|
Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.401
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.400
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.399
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.395
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.392
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.392
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.390
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.390
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.390
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.388
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.388
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.385
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.383
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.381
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.377
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.376
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.375
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.374
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.368
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.365
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.364
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.364
|
|
|
|
smooth muscle cell chemotaxis
|
GO:0071670 |
2 |
0.361
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.359
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.356
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.354
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.354
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.354
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.352
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.351
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.350
|
Fly |
|
|
blood circulation
|
GO:0008015 |
195 |
0.350
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.350
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.349
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.348
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.345
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.343
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.342
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.342
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.341
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.341
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.338
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.329
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.329
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.328
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.328
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.328
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.327
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.325
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.323
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.322
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.320
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.319
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.319
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.318
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.318
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.318
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.318
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.314
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.310
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.309
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.308
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.307
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.307
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.301
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.298
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.297
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.296
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.295
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.293
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.293
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.292
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.292
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.290
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.290
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.289
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.289
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.287
|
Fly |
|
|
regulation of pigment cell differentiation
|
GO:0050932 |
7 |
0.287
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.286
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.286
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.285
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.285
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.284
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.284
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.283
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.282
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.281
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.280
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.279
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.279
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.279
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.279
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.274
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.274
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.272
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.271
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.268
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.266
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.265
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.264
|
|
|
|
metanephric glomerular mesangium development
|
GO:0072223 |
3 |
0.263
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.262
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.262
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.261
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.260
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.259
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.257
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.257
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.256
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.256
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.254
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.252
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.251
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.251
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.250
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.250
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
9 |
0.250
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.249
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.247
|
Fly |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.247
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.246
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.246
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.243
|
Fly |
|
|
phosphatidylinositol biosynthetic process
|
GO:0006661 |
15 |
0.242
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.242
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.241
|
Mouse |
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.238
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.238
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.236
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.236
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.236
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.236
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.235
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.234
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.231
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.230
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.230
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.228
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.228
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.227
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.227
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.224
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.224
|
|
|
|
developmental pigmentation
|
GO:0048066 |
40 |
0.224
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.223
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.221
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.221
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.221
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.220
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.220
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.220
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.220
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.219
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.219
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.216
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.216
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.216
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.215
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.213
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.213
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.212
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.212
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.211
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.209
|
Human |
|
|
exocrine system development
|
GO:0035272 |
45 |
0.208
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.208
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.207
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.207
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.206
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.206
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.206
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.205
|
|
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.205
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.205
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.205
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.203
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.200
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.200
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
3 |
0.199
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.198
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.198
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.197
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.197
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.197
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.196
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.196
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.196
|
|
|
|
intercellular bridge organization
|
GO:0043063 |
1 |
0.195
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.193
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.193
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.193
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.192
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.192
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.191
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.191
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.190
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.190
|
|
