Mus musculus

0 known processes

Cbr1

carbonyl reductase 1

(Aliases: Cbr,CR,AW261796)

Cbr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.551
Rat
glutathione metabolic process GO:0006749 16 0.543
cellular amino acid metabolic process GO:0006520 103 0.435
cellular modified amino acid metabolic process GO:0006575 63 0.308
monocyte chemotactic protein 1 production GO:0071605 1 0.282
sulfur compound metabolic process GO:0006790 100 0.271
monocarboxylic acid metabolic process GO:0032787 191 0.227
cellular lipid metabolic process GO:0044255 323 0.196
fatty acid metabolic process GO:0006631 121 0.144
peptide metabolic process GO:0006518 46 0.143
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 1 0.124
negative regulation of cellular protein metabolic process GO:0032269 247 0.101
organic heteropentacyclic compound catabolic process GO:1901377 1 0.096
negative regulation of cell proliferation GO:0008285 296 0.090
response to organonitrogen compound GO:0010243 246 0.088
secondary metabolite catabolic process GO:0090487 1 0.088
regulation of cellular amino acid metabolic process GO:0006521 5 0.077
response to organic cyclic compound GO:0014070 198 0.076
Rat
cellular amide metabolic process GO:0043603 58 0.075
amine metabolic process GO:0009308 45 0.073
aflatoxin metabolic process GO:0046222 1 0.070
negative regulation of protein metabolic process GO:0051248 282 0.069
lipid oxidation GO:0034440 29 0.067
regulation of reactive oxygen species metabolic process GO:2000377 40 0.067
reactive oxygen species metabolic process GO:0072593 84 0.066
mapk cascade GO:0000165 281 0.065
cellular amine metabolic process GO:0044106 44 0.058
regulation of protein kinase activity GO:0045859 232 0.058
negative regulation of protein modification process GO:0031400 163 0.058
negative regulation of phosphate metabolic process GO:0045936 184 0.057
erk1 and erk2 cascade GO:0070371 77 0.056
negative regulation of peroxidase activity GO:2000469 1 0.055
toxin catabolic process GO:0009407 1 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.050
negative regulation of chemokine production GO:0032682 4 0.050
regulation of mapk cascade GO:0043408 248 0.049
regulation of transferase activity GO:0051338 263 0.047
regulation of kinase activity GO:0043549 249 0.046
lipid biosynthetic process GO:0008610 179 0.044
leukocyte proliferation GO:0070661 172 0.044
transmembrane transport GO:0055085 412 0.042
response to inorganic substance GO:0010035 96 0.042
negative regulation of monocyte chemotactic protein 1 production GO:0071638 1 0.041
negative regulation of phosphorylation GO:0042326 166 0.041
negative regulation of phosphorus metabolic process GO:0010563 184 0.040
regulation of leukocyte proliferation GO:0070663 121 0.040
xenobiotic catabolic process GO:0042178 1 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
negative regulation of molecular function GO:0044092 258 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
protein oligomerization GO:0051259 67 0.037
maintenance of location GO:0051235 89 0.036
regulation of cytokine production GO:0001817 266 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.036
nucleotide metabolic process GO:0009117 332 0.035
small molecule catabolic process GO:0044282 71 0.034
Rat
macromolecule catabolic process GO:0009057 281 0.033
negative regulation of apoptotic signaling pathway GO:2001234 104 0.033
fatty acid derivative metabolic process GO:1901568 33 0.033
regulation of organelle organization GO:0033043 289 0.033
cellular response to lipid GO:0071396 145 0.032
renal system development GO:0072001 225 0.032
kidney development GO:0001822 213 0.032
cellular response to lipopolysaccharide GO:0071222 77 0.031
apoptotic signaling pathway GO:0097190 306 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
microtubule based process GO:0007017 236 0.031
negative regulation of intracellular signal transduction GO:1902532 167 0.030
regulation of hormone levels GO:0010817 211 0.030
response to metal ion GO:0010038 47 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
response to lipopolysaccharide GO:0032496 128 0.029
Rat
nucleoside phosphate metabolic process GO:0006753 338 0.029
steroid metabolic process GO:0008202 119 0.029
nucleoside metabolic process GO:0009116 246 0.029
cellular ketone metabolic process GO:0042180 84 0.029
Rat
cellular response to molecule of bacterial origin GO:0071219 83 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
response to oxidative stress GO:0006979 123 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
response to extracellular stimulus GO:0009991 127 0.028
protein tetramerization GO:0051262 23 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.028
regulation of cellular response to stress GO:0080135 159 0.028
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.027
cytokine production GO:0001816 319 0.027
unsaturated fatty acid metabolic process GO:0033559 31 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
cellular response to inorganic substance GO:0071241 37 0.026
response to reactive oxygen species GO:0000302 56 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
negative regulation of kinase activity GO:0033673 81 0.026
ossification GO:0001503 216 0.026
negative regulation of transferase activity GO:0051348 85 0.026
membrane organization GO:0061024 245 0.026
protein catabolic process GO:0030163 221 0.025
cellular lipid catabolic process GO:0044242 52 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
nitrogen compound transport GO:0071705 271 0.025
homeostasis of number of cells GO:0048872 210 0.024
lipid localization GO:0010876 126 0.024
heterocycle catabolic process GO:0046700 280 0.024
small molecule biosynthetic process GO:0044283 132 0.024
stress activated mapk cascade GO:0051403 80 0.023
stress activated protein kinase signaling cascade GO:0031098 81 0.023
urogenital system development GO:0001655 261 0.023
protein homooligomerization GO:0051260 43 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
lipid catabolic process GO:0016042 69 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
coenzyme metabolic process GO:0006732 52 0.022
Rat
superoxide metabolic process GO:0006801 27 0.022
response to light stimulus GO:0009416 135 0.022
cofactor metabolic process GO:0051186 80 0.022
Rat
regulation of peroxidase activity GO:2000468 1 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
organic acid catabolic process GO:0016054 51 0.021
carboxylic acid catabolic process GO:0046395 51 0.021
peptidyl amino acid modification GO:0018193 336 0.021
response to nutrient levels GO:0031667 109 0.021
regulation of protein localization GO:0032880 231 0.020
i kappab kinase nf kappab signaling GO:0007249 85 0.020
cation transport GO:0006812 399 0.020
ion transmembrane transport GO:0034220 361 0.020
regulation of intracellular transport GO:0032386 159 0.020
germ cell development GO:0007281 185 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
regulation of monocyte chemotactic protein 1 production GO:0071637 1 0.020
positive regulation of organelle organization GO:0010638 128 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cell type specific apoptotic process GO:0097285 268 0.019
ketone catabolic process GO:0042182 3 0.019
Rat
positive regulation of protein modification process GO:0031401 299 0.019
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
regulation of membrane potential GO:0042391 192 0.019
icosanoid metabolic process GO:0006690 33 0.019
regulation of map kinase activity GO:0043405 120 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
myeloid cell differentiation GO:0030099 233 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
sensory perception GO:0007600 245 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
lipid modification GO:0030258 65 0.019
sensory organ morphogenesis GO:0090596 242 0.018
monocarboxylic acid catabolic process GO:0072329 27 0.018
neuronal action potential GO:0019228 54 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
defense response to other organism GO:0098542 197 0.018
regulation of cell activation GO:0050865 289 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
synaptic transmission GO:0007268 329 0.018
response to radiation GO:0009314 165 0.018
purine containing compound metabolic process GO:0072521 311 0.018
regulation of chemokine production GO:0032642 30 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
negative regulation of map kinase activity GO:0043407 34 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
regulation of secretion GO:0051046 274 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
jnk cascade GO:0007254 72 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
regulation of jnk cascade GO:0046328 62 0.017
hormone metabolic process GO:0042445 86 0.017
aflatoxin catabolic process GO:0046223 1 0.017
regulation of stress activated mapk cascade GO:0032872 69 0.017
chemokine production GO:0032602 34 0.017
male gamete generation GO:0048232 285 0.017
multicellular organismal signaling GO:0035637 91 0.017
energy derivation by oxidation of organic compounds GO:0015980 77 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
negative regulation of cytokine production GO:0001818 84 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.017
branched chain amino acid catabolic process GO:0009083 2 0.016
fatty acid alpha oxidation GO:0001561 2 0.016
fatty acid oxidation GO:0019395 28 0.016
spermatogenesis GO:0007283 284 0.016
kidney epithelium development GO:0072073 121 0.016
regulation of secretion by cell GO:1903530 249 0.016
negative regulation of leukocyte proliferation GO:0070664 46 0.016
response to growth factor GO:0070848 198 0.016
developmental maturation GO:0021700 193 0.016
regulation of defense response GO:0031347 233 0.016
skeletal system development GO:0001501 356 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
positive regulation of cell development GO:0010720 237 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
transmission of nerve impulse GO:0019226 76 0.016
muscle tissue development GO:0060537 308 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
toxin metabolic process GO:0009404 5 0.015
skin development GO:0043588 220 0.015
intracellular protein transport GO:0006886 204 0.015
cytoplasmic transport GO:0016482 234 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
protein localization to organelle GO:0033365 185 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
camera type eye development GO:0043010 266 0.015
locomotory behavior GO:0007626 195 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
Rat
regulation of neuron death GO:1901214 134 0.015
forebrain development GO:0030900 302 0.015
dna metabolic process GO:0006259 303 0.014
mesonephros development GO:0001823 97 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of superoxide anion generation GO:0032928 4 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
negative regulation of jun kinase activity GO:0043508 9 0.014
regulation of cell motility GO:2000145 236 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
cellular protein catabolic process GO:0044257 155 0.014
negative regulation of interleukin 1 beta production GO:0032691 5 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
hydrogen ion transmembrane transport GO:1902600 25 0.013
nuclear division GO:0000280 158 0.013
aromatic compound catabolic process GO:0019439 286 0.013
chromatin organization GO:0006325 206 0.013
glial cell differentiation GO:0010001 131 0.013
action potential GO:0001508 78 0.013
gland development GO:0048732 330 0.013
adult behavior GO:0030534 135 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
cation transmembrane transport GO:0098655 266 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
nuclear transport GO:0051169 139 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
ras protein signal transduction GO:0007265 77 0.013
lymphocyte proliferation GO:0046651 164 0.013
leukocyte differentiation GO:0002521 342 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
proton transport GO:0015992 35 0.013
mesonephric epithelium development GO:0072163 94 0.013
cellular response to cadmium ion GO:0071276 3 0.013
regulation of ion transport GO:0043269 215 0.013
inflammatory response GO:0006954 244 0.013
positive regulation of secretion GO:0051047 130 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
lateral inhibition GO:0046331 1 0.012
retinoid metabolic process GO:0001523 24 0.012
regulation of binding GO:0051098 111 0.012
innate immune response GO:0045087 157 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
endocytosis GO:0006897 168 0.012
regulation of ossification GO:0030278 112 0.012
mitochondrion organization GO:0007005 134 0.012
striated muscle tissue development GO:0014706 293 0.012
organelle fission GO:0048285 170 0.012
cellular protein complex assembly GO:0043623 116 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
cellular response to metal ion GO:0071248 31 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
secondary metabolic process GO:0019748 18 0.012
amide transport GO:0042886 138 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
bone development GO:0060348 120 0.012
muscle cell differentiation GO:0042692 261 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
positive regulation of protein kinase activity GO:0045860 144 0.011
neuron apoptotic process GO:0051402 142 0.011
protein ubiquitination GO:0016567 171 0.011
bile acid secretion GO:0032782 2 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of t cell activation GO:0050863 170 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.011
regulation of hydrolase activity GO:0051336 246 0.011
cation homeostasis GO:0055080 212 0.011
cellular response to external stimulus GO:0071496 88 0.011
organic hydroxy compound transport GO:0015850 93 0.011
terpenoid metabolic process GO:0006721 25 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of proteolysis GO:0030162 164 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
positive regulation of transferase activity GO:0051347 167 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of jun kinase activity GO:0043506 40 0.011
regulation of interleukin 1 production GO:0032652 26 0.011
cellular homeostasis GO:0019725 240 0.011
protein localization to membrane GO:0072657 108 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of fibroblast proliferation GO:0048145 34 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
response to stilbenoid GO:0035634 22 0.011
asymmetric stem cell division GO:0098722 3 0.011
epithelial cell development GO:0002064 159 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
membrane depolarization GO:0051899 64 0.011
metal ion homeostasis GO:0055065 189 0.011
nucleoside catabolic process GO:0009164 206 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine containing compound catabolic process GO:0072523 213 0.010
protein localization to nucleus GO:0034504 121 0.010
cell division GO:0051301 120 0.010
negative regulation of organelle organization GO:0010639 90 0.010
circulatory system process GO:0003013 197 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
anatomical structure homeostasis GO:0060249 145 0.010
visual behavior GO:0007632 45 0.010
substantia nigra development GO:0021762 2 0.010
organelle localization GO:0051640 179 0.010
glial cell development GO:0021782 54 0.010
protein acylation GO:0043543 64 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
protein targeting GO:0006605 143 0.010
response to drug GO:0042493 75 0.010
positive regulation of chromosome segregation GO:0051984 4 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.010

Cbr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.053
inherited metabolic disorder DOID:655 0 0.017