Mus musculus

64 known processes

Cbx1

chromobox homolog 1 (Drosophila HP1 beta)

(Aliases: MOD1,Cbx-rs2,M31,E430007M08Rik,Cbx,HP1B)

Cbx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna alkylation GO:0006305 43 0.788
Fly
dna metabolic process GO:0006259 303 0.717
Fly
chromatin assembly GO:0031497 13 0.710
Fly
methylation GO:0032259 134 0.704
Fly
macromolecule methylation GO:0043414 120 0.630
Fly
dna dealkylation GO:0035510 11 0.546
dna modification GO:0006304 50 0.517
Fly
chromatin organization GO:0006325 206 0.486
Fly
dna methylation GO:0006306 43 0.463
Fly
negative regulation of cell cycle GO:0045786 123 0.422
protein catabolic process GO:0030163 221 0.420
macromolecule catabolic process GO:0009057 281 0.419
signal transduction by p53 class mediator GO:0072331 51 0.414
chromatin assembly or disassembly GO:0006333 16 0.374
Fly
dna repair GO:0006281 107 0.363
histone h3 k9 dimethylation GO:0036123 4 0.348
Fly
cellular response to dna damage stimulus GO:0006974 207 0.312
dna conformation change GO:0071103 37 0.225
Fly
dna packaging GO:0006323 30 0.222
Fly
chromatin modification GO:0016568 187 0.216
Fly
protein modification by small protein conjugation GO:0032446 187 0.205
genetic imprinting GO:0071514 27 0.197
cellular amine metabolic process GO:0044106 44 0.196
mitotic cell cycle GO:0000278 195 0.181
negative regulation of cellular component organization GO:0051129 194 0.170
cellular ketone metabolic process GO:0042180 84 0.167
regulation of cell cycle GO:0051726 281 0.164
nuclear division GO:0000280 158 0.153
response to vitamin d GO:0033280 3 0.152
regulation of cellular amine metabolic process GO:0033238 20 0.147
protein methylation GO:0006479 81 0.145
Fly
cellular response to vitamin GO:0071295 2 0.145
cellular response to nutrient levels GO:0031669 64 0.142
cellular macromolecule catabolic process GO:0044265 206 0.141
histone h3 k9 methylation GO:0051567 17 0.140
Fly
covalent chromatin modification GO:0016569 163 0.137
Fly
protein dna complex subunit organization GO:0071824 28 0.135
mesenchymal cell differentiation GO:0048762 107 0.135
histone modification GO:0016570 159 0.133
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.124
protein modification by small protein conjugation or removal GO:0070647 207 0.123
amine metabolic process GO:0009308 45 0.122
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
developmental growth involved in morphogenesis GO:0060560 138 0.118
peptidyl amino acid modification GO:0018193 336 0.116
Fly
negative regulation of nuclear division GO:0051784 19 0.106
convergent extension GO:0060026 14 0.106
regulation of organelle organization GO:0033043 289 0.105
Fly
positive regulation of histone h3 k9 methylation GO:0051574 4 0.100
Fly
cellular response to lipid GO:0071396 145 0.098
negative regulation of cell proliferation GO:0008285 296 0.098
organelle fission GO:0048285 170 0.095
modification dependent macromolecule catabolic process GO:0043632 133 0.094
protein ubiquitination GO:0016567 171 0.093
nucleotide excision repair GO:0006289 13 0.092
protein processing GO:0016485 163 0.091
regulation of dna methylation GO:0044030 12 0.091
Fly
double strand break repair GO:0006302 48 0.091
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
embryonic placenta development GO:0001892 98 0.089
stem cell differentiation GO:0048863 268 0.088
regulation of transcription by chromatin organization GO:0034401 0 0.087
intracellular receptor signaling pathway GO:0030522 74 0.087
regulation of vitamin d receptor signaling pathway GO:0070562 2 0.086
peptidyl lysine modification GO:0018205 77 0.086
Fly
negative regulation of protein metabolic process GO:0051248 282 0.086
cellular response to extracellular stimulus GO:0031668 81 0.085
multi multicellular organism process GO:0044706 109 0.083
response to organic cyclic compound GO:0014070 198 0.083
regulation of histone methylation GO:0031060 30 0.081
Fly
negative regulation of cellular catabolic process GO:0031330 47 0.081
changes to dna methylation involved in embryo development GO:1901538 6 0.080
protein maturation GO:0051604 176 0.079
mitotic cell cycle process GO:1903047 159 0.077
cellular response to external stimulus GO:0071496 88 0.076
anatomical structure homeostasis GO:0060249 145 0.076
Fly
divalent inorganic cation homeostasis GO:0072507 138 0.075
mesenchyme development GO:0060485 152 0.074
regulation of chromosome organization GO:0033044 83 0.072
Fly
protein autophosphorylation GO:0046777 61 0.071
axis elongation GO:0003401 30 0.071
negative regulation of cell cycle process GO:0010948 69 0.070
regulation of chromatin modification GO:1903308 57 0.069
Fly
regulation of protein stability GO:0031647 52 0.069
regulation of mitotic cell cycle phase transition GO:1901990 73 0.068
negative regulation of cell cycle phase transition GO:1901988 48 0.067
negative regulation of protein processing GO:0010955 79 0.067
axonogenesis GO:0007409 274 0.067
chromosome segregation GO:0007059 48 0.066
posttranscriptional regulation of gene expression GO:0010608 155 0.066
negative regulation of mitotic cell cycle GO:0045930 58 0.064
regulation of cell cycle process GO:0010564 160 0.064
positive regulation of histone methylation GO:0031062 16 0.063
Fly
ubiquitin dependent protein catabolic process GO:0006511 129 0.062
heterochromatin organization GO:0070828 4 0.061
Fly
multicellular organism growth GO:0035264 161 0.058
Worm
regulation of protein maturation GO:1903317 96 0.058
response to radiation GO:0009314 165 0.058
stem cell development GO:0048864 219 0.058
histone methylation GO:0016571 71 0.057
Fly
dna methylation involved in embryo development GO:0043045 6 0.057
microtubule cytoskeleton organization GO:0000226 157 0.056
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.056
regulation of genetic imprinting GO:2000653 5 0.056
mesenchymal cell development GO:0014031 93 0.056
dna endoreduplication GO:0042023 4 0.055
cellular amino acid metabolic process GO:0006520 103 0.055
cellular response to vitamin d GO:0071305 2 0.053
peptidyl lysine methylation GO:0018022 29 0.053
Fly
demethylation GO:0070988 23 0.052
regulation of response to alcohol GO:1901419 2 0.050
regulation of histone h3 k9 methylation GO:0051570 8 0.050
Fly
chromosome separation GO:0051304 14 0.050
negative regulation of cellular protein catabolic process GO:1903363 22 0.049
mitotic cell cycle checkpoint GO:0007093 31 0.049
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.048
microtubule based process GO:0007017 236 0.047
regulation of protein processing GO:0070613 96 0.047
germ cell development GO:0007281 185 0.047
Worm
cellular response to hormone stimulus GO:0032870 150 0.046
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.045
response to ionizing radiation GO:0010212 42 0.044
epithelial to mesenchymal transition GO:0001837 47 0.044
negative regulation of proteolysis GO:0045861 74 0.044
chromatin remodeling GO:0006338 32 0.043
Fly
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.043
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.043
negative regulation of protein catabolic process GO:0042177 36 0.042
chemotaxis GO:0006935 247 0.042
neuron projection guidance GO:0097485 141 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.041
regulation of nuclear division GO:0051783 56 0.041
proteasomal protein catabolic process GO:0010498 98 0.041
negative regulation of protein maturation GO:1903318 79 0.040
response to extracellular stimulus GO:0009991 127 0.040
meiotic cell cycle process GO:1903046 77 0.040
vitamin d receptor signaling pathway GO:0070561 2 0.039
cellular protein catabolic process GO:0044257 155 0.038
ras protein signal transduction GO:0007265 77 0.038
Worm
mitotic nuclear division GO:0007067 48 0.036
cell division GO:0051301 120 0.035
negative regulation of organelle organization GO:0010639 90 0.035
meiotic cell cycle GO:0051321 122 0.035
modification dependent protein catabolic process GO:0019941 133 0.035
negative regulation of chromosome organization GO:2001251 30 0.035
positive regulation of apoptotic process GO:0043065 217 0.034
regulation of hydrolase activity GO:0051336 246 0.032
heterochromatin assembly GO:0031507 2 0.032
Fly
regulation of mitosis GO:0007088 29 0.031
positive regulation of programmed cell death GO:0043068 218 0.031
regulation of histone modification GO:0031056 56 0.031
Fly
dendrite development GO:0016358 115 0.031
convergent extension involved in axis elongation GO:0060028 7 0.030
dna recombination GO:0006310 92 0.030
response to alcohol GO:0097305 48 0.029
embryonic placenta morphogenesis GO:0060669 25 0.029
negative regulation of cell division GO:0051782 24 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
Worm
regulation of proteolysis GO:0030162 164 0.028
muscle cell differentiation GO:0042692 261 0.028
b cell activation GO:0042113 161 0.027
axon guidance GO:0007411 141 0.027
negative regulation of molecular function GO:0044092 258 0.027
positive regulation of cellular component biogenesis GO:0044089 94 0.027
Fly
response to nutrient levels GO:0031667 109 0.027
dna replication GO:0006260 52 0.027
apoptotic signaling pathway GO:0097190 306 0.025
negative regulation of dna demethylation GO:1901536 2 0.025
regulation of chromosome segregation GO:0051983 21 0.025
cellular response to organic cyclic compound GO:0071407 87 0.025
regulation of proteasomal protein catabolic process GO:0061136 46 0.024
negative regulation of dna replication GO:0008156 4 0.024
double strand break repair via homologous recombination GO:0000724 21 0.024
regulation of ras protein signal transduction GO:0046578 114 0.023
Worm
cellular response to estrogen stimulus GO:0071391 12 0.023
recombinational repair GO:0000725 21 0.023
regulation of cell activation GO:0050865 289 0.023
mitotic spindle checkpoint GO:0071174 9 0.023
nucleosome assembly GO:0006334 7 0.022
innate immune response GO:0045087 157 0.022
positive regulation of chromatin modification GO:1903310 28 0.022
Fly
calcium ion homeostasis GO:0055074 127 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.022
positive regulation of protein modification process GO:0031401 299 0.022
Fly
regulation of protein localization GO:0032880 231 0.022
regulation of dna demethylation GO:1901535 2 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.021
myeloid cell homeostasis GO:0002262 114 0.021
regulation of chromatin silencing GO:0031935 2 0.021
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of multi organism process GO:0043900 111 0.020
organelle assembly GO:0070925 177 0.020
mitotic sister chromatid separation GO:0051306 9 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
positive regulation of cell death GO:0010942 224 0.019
positive regulation of cell development GO:0010720 237 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
Fly
regulation of binding GO:0051098 111 0.018
aromatic compound catabolic process GO:0019439 286 0.018
cellular response to steroid hormone stimulus GO:0071383 33 0.018
embryonic organ morphogenesis GO:0048562 276 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
positive regulation of histone modification GO:0031058 28 0.017
Fly
regulation of epithelial cell proliferation GO:0050678 141 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
cytoplasmic transport GO:0016482 234 0.017
regulation of kinase activity GO:0043549 249 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
homeostasis of number of cells GO:0048872 210 0.017
peptidyl lysine trimethylation GO:0018023 12 0.017
Fly
regulation of establishment of protein localization GO:0070201 181 0.017
regulation of lymphocyte activation GO:0051249 240 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
spindle checkpoint GO:0031577 12 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of cellular response to stress GO:0080135 159 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
purine containing compound metabolic process GO:0072521 311 0.016
cation homeostasis GO:0055080 212 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.016
nucleoside metabolic process GO:0009116 246 0.016
protein localization to organelle GO:0033365 185 0.016
wnt signaling pathway GO:0016055 188 0.016
positive regulation of cell cycle GO:0045787 92 0.016
regulation of sister chromatid segregation GO:0033045 13 0.015
mrna splicing via spliceosome GO:0000398 43 0.015
protein acylation GO:0043543 64 0.015
response to organonitrogen compound GO:0010243 246 0.015
regulation of mitotic sister chromatid segregation GO:0033047 12 0.015
nucleotide catabolic process GO:0009166 217 0.015
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
sister chromatid segregation GO:0000819 20 0.015
developmental maturation GO:0021700 193 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
cellular response to alcohol GO:0097306 23 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
spermatid development GO:0007286 108 0.014
cation transport GO:0006812 399 0.014
translation GO:0006412 93 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
regulation of protein catabolic process GO:0042176 108 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
positive regulation of organelle organization GO:0010638 128 0.014
Fly
response to molecule of bacterial origin GO:0002237 143 0.014
regionalization GO:0003002 337 0.014
negative regulation of protein modification process GO:0031400 163 0.014
striated muscle tissue development GO:0014706 293 0.014
digestive tract development GO:0048565 190 0.014
negative regulation of mitosis GO:0045839 10 0.014
cellular response to acid chemical GO:0071229 68 0.014
myeloid cell differentiation GO:0030099 233 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of response to dna damage stimulus GO:2001020 34 0.014
positive regulation of cell activation GO:0050867 158 0.014
negative regulation of nervous system development GO:0051961 156 0.013
negative regulation of transferase activity GO:0051348 85 0.013
response to light stimulus GO:0009416 135 0.013
spermatogenesis GO:0007283 284 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
placenta development GO:0001890 140 0.013
skin development GO:0043588 220 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
maintenance of location GO:0051235 89 0.013
inflammatory response GO:0006954 244 0.013
connective tissue development GO:0061448 179 0.013
response to gamma radiation GO:0010332 22 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
protein polymerization GO:0051258 57 0.013
meiotic nuclear division GO:0007126 115 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
cell cycle checkpoint GO:0000075 47 0.013
digestive system development GO:0055123 200 0.013
regulation of hormone levels GO:0010817 211 0.013
mitotic sister chromatid segregation GO:0000070 14 0.013
dna templated transcription termination GO:0006353 4 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to estrogen GO:0043627 24 0.012
rhythmic process GO:0048511 174 0.012
centromere complex assembly GO:0034508 3 0.012
digestive tract morphogenesis GO:0048546 147 0.012
cell maturation GO:0048469 127 0.012
rrna transcription GO:0009303 9 0.012
ear development GO:0043583 200 0.012
skeletal system development GO:0001501 356 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of intracellular transport GO:0032386 159 0.012
interspecies interaction between organisms GO:0044419 83 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
nuclear transport GO:0051169 139 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
dephosphorylation GO:0016311 129 0.012
negative regulation of growth GO:0045926 99 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
regulation of membrane potential GO:0042391 192 0.012
inositol phosphate catabolic process GO:0071545 4 0.012
negative regulation of chromatin modification GO:1903309 19 0.012
cellular protein complex assembly GO:0043623 116 0.012
calcium ion transport GO:0006816 159 0.012
response to steroid hormone GO:0048545 56 0.012
intestinal epithelial structure maintenance GO:0060729 4 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
respiratory tube development GO:0030323 167 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of response to wounding GO:1903034 189 0.011
cellular response to gamma radiation GO:0071480 4 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
neural precursor cell proliferation GO:0061351 121 0.011
cellular response to nutrient GO:0031670 7 0.011
telomere maintenance in response to dna damage GO:0043247 4 0.011
forebrain development GO:0030900 302 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
rna interference GO:0016246 2 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
immune effector process GO:0002252 321 0.011
regulation of protein kinase activity GO:0045859 232 0.011
sensory perception GO:0007600 245 0.011
camera type eye development GO:0043010 266 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of growth GO:0045927 104 0.011
Worm
gland development GO:0048732 330 0.011
protein targeting GO:0006605 143 0.011
compound eye development GO:0048749 1 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
tissue homeostasis GO:0001894 115 0.011
sequestering of calcium ion GO:0051208 18 0.011
male gamete generation GO:0048232 285 0.011
mrna processing GO:0006397 63 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.010
nucleotide metabolic process GO:0009117 332 0.010
regulation of body fluid levels GO:0050878 162 0.010
transmission of nerve impulse GO:0019226 76 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
Worm
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
cation transmembrane transport GO:0098655 266 0.010
response to oxidative stress GO:0006979 123 0.010
regulation of chromatin organization GO:1902275 57 0.010
Fly
metal ion homeostasis GO:0055065 189 0.010
spermatid differentiation GO:0048515 115 0.010
regulation of myeloid cell differentiation GO:0045637 96 0.010
histone acetylation GO:0016573 41 0.010
intracellular mrna localization GO:0008298 4 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.010
organism emergence from protective structure GO:0071684 4 0.010
cognition GO:0050890 149 0.010
Worm

Cbx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.533
disease of cellular proliferation DOID:14566 0 0.533
organ system cancer DOID:0050686 0 0.268
endocrine gland cancer DOID:170 0 0.068
thyroid cancer DOID:1781 0 0.032
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
hematopoietic system disease DOID:74 0 0.013
nervous system disease DOID:863 0 0.012