|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.984
|
Mouse Worm |
|
|
regulation of saliva secretion
|
GO:0046877 |
2 |
0.981
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.980
|
Mouse |
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.980
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.975
|
Mouse |
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.968
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
16 |
0.967
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.966
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.961
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.958
|
|
|
|
opioid receptor signaling pathway
|
GO:0038003 |
5 |
0.953
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.949
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.949
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.941
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.939
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.934
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.933
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.926
|
Human Mouse Rat Worm |
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.926
|
Mouse |
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.921
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.912
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.908
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.905
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.900
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.899
|
Mouse |
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.895
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
7 |
0.894
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.892
|
|
|
|
positive regulation of heart rate
|
GO:0010460 |
10 |
0.884
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.881
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.872
|
Mouse Rat |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.871
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.868
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.863
|
Mouse |
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.858
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.851
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.850
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.844
|
Human |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.838
|
Mouse |
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.836
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.835
|
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.832
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.827
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.826
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.823
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.813
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.808
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.802
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.800
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.796
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.794
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.791
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.784
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.783
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.780
|
Rat |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.779
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.778
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.777
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.763
|
Rat |
|
|
heart contraction
|
GO:0060047 |
93 |
0.762
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
16 |
0.754
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.751
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.747
|
Rat |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.746
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.745
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.743
|
Rat |
|
|
operant conditioning
|
GO:0035106 |
2 |
0.741
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.736
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
13 |
0.725
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.724
|
Mouse |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.718
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.715
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
8 |
0.713
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.706
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.701
|
Human |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.695
|
Rat |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.691
|
Human |
|
|
cognition
|
GO:0050890 |
149 |
0.685
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.677
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.676
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.674
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.674
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.673
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.673
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.658
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.654
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.649
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.648
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.640
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.640
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.632
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.627
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.625
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.615
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.603
|
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
14 |
0.599
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.596
|
Mouse |
|
|
negative regulation of cyclic nucleotide metabolic process
|
GO:0030800 |
5 |
0.596
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.586
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.586
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.585
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.585
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.581
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.578
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
22 |
0.578
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.572
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.567
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.566
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.564
|
|
|
|
cerebral cortex gabaergic interneuron migration
|
GO:0021853 |
6 |
0.561
|
|
|
|
substrate independent telencephalic tangential migration
|
GO:0021826 |
8 |
0.554
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.549
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.547
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.533
|
Human |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.530
|
Rat |
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
6 |
0.528
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.527
|
Rat |
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.522
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.507
|
Mouse |
|
|
associative learning
|
GO:0008306 |
61 |
0.506
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.501
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.495
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.492
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
18 |
0.488
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
6 |
0.474
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.472
|
Rat |
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.466
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
10 |
0.463
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.463
|
|
|
|
negative regulation of camp metabolic process
|
GO:0030815 |
5 |
0.462
|
|
|
|
negative regulation of adenylate cyclase activity
|
GO:0007194 |
1 |
0.444
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.439
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.438
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.421
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
12 |
0.421
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.419
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.419
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.415
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.414
|
Mouse |
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.410
|
Rat |
|
|
peristalsis
|
GO:0030432 |
8 |
0.406
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.402
|
Rat |
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.402
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.399
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.398
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.396
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.395
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.386
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
13 |
0.384
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.383
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.381
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.378
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.376
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.373
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.365
|
Mouse |
|
|
cerebral cortex gabaergic interneuron differentiation
|
GO:0021892 |
9 |
0.364
|
|
|
|
response to amine
|
GO:0014075 |
16 |
0.360
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.360
|
|
|
|
memory
|
GO:0007613 |
58 |
0.359
|
|
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.358
|
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.355
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.354
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.351
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.344
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.343
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.342
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.340
|
Rat |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.338
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.337
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.334
|
Rat |
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.334
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.332
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.331
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.330
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.327
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.325
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.325
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
5 |
0.322
|
|
|
|
cerebral cortex neuron differentiation
|
GO:0021895 |
19 |
0.321
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.320
|
|
|
|
cerebral cortex gabaergic interneuron development
|
GO:0021894 |
6 |
0.320
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.314
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.312
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.307
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.307
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.306
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.303
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.303
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.301
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.301
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.300
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.298
|
Rat |
|
|
bronchiole morphogenesis
|
GO:0060436 |
1 |
0.295
|
|
|
|
learning
|
GO:0007612 |
98 |
0.291
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.291
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.288
|
Rat |
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.287
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.285
|
Rat |
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.283
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.282
|
Human |
|
|
cell maturation
|
GO:0048469 |
127 |
0.279
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.273
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.273
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.269
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.268
|
|
|
|
regulation of inward rectifier potassium channel activity
|
GO:1901979 |
1 |
0.267
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.266
|
|
|
|
negative regulation of lyase activity
|
GO:0051350 |
1 |
0.265
|
|
|
|
negative regulation of camp biosynthetic process
|
GO:0030818 |
5 |
0.264
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
5 |
0.263
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.263
|
Human |
|
|
interneuron migration from the subpallium to the cortex
|
GO:0021830 |
7 |
0.263
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
20 |
0.259
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.256
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.253
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.253
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.248
|
Mouse |
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.246
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.245
|
|
|
|
dopamine metabolic process
|
GO:0042417 |
23 |
0.245
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.243
|
Human |
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.242
|
Mouse Rat |
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.240
|
Mouse |
|
|
hippocampus development
|
GO:0021766 |
52 |
0.240
|
|
|
|
behavioral response to cocaine
|
GO:0048148 |
10 |
0.239
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
7 |
0.239
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.238
|
|
|
|
regulation of g protein activated inward rectifier potassium channel activity
|
GO:1900128 |
1 |
0.237
|
|
|
|
regulation of dopamine metabolic process
|
GO:0042053 |
10 |
0.237
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.235
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.235
|
Rat |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.232
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.231
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.228
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.228
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.225
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.223
|
Mouse |
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.220
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.218
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.217
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.217
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
5 |
0.214
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.214
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.213
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
3 |
0.212
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.212
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.212
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
10 |
0.212
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.211
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.210
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.210
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.209
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.209
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.207
|
|
|
|
regulation of appetite
|
GO:0032098 |
12 |
0.207
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.206
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
21 |
0.206
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.205
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.205
|
Mouse |
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.204
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.200
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.199
|
|
|
|
catecholamine transport
|
GO:0051937 |
21 |
0.198
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.198
|
|
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
6 |
0.197
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.197
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.196
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.195
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.193
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.191
|
Rat |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.190
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.188
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.188
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.187
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.187
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.186
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.185
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.183
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.181
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.181
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.177
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.176
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.176
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.176
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.173
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.172
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.172
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.170
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.168
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.166
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.166
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.166
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.165
|
Human |
|
|
male sex determination
|
GO:0030238 |
14 |
0.165
|
|
|
|
behavioral defense response
|
GO:0002209 |
28 |
0.164
|
Rat |
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.163
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.161
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.160
|
|
|
|
gabaergic neuron differentiation
|
GO:0097154 |
11 |
0.159
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.158
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.158
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.157
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.156
|
Mouse Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.155
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.155
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.154
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.153
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.153
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.152
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.150
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.149
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.149
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.149
|
Mouse |
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.149
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.149
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.147
|
|
|
|
endocrine pancreas development
|
GO:0031018 |
29 |
0.147
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.146
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.145
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.145
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.144
|
Human |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.142
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.141
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.140
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.138
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.134
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.134
|
|
|
|
negative regulation of smooth muscle contraction
|
GO:0045986 |
10 |
0.134
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
21 |
0.132
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.132
|
|
|
|
central nervous system myelination
|
GO:0022010 |
12 |
0.130
|
|
|
|
positive regulation of high voltage gated calcium channel activity
|
GO:1901843 |
1 |
0.129
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.128
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.127
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.126
|
Mouse Rat |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.126
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.126
|
|
|
|
positive regulation of synaptic transmission glutamatergic
|
GO:0051968 |
8 |
0.125
|
Rat |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.125
|
|
|
|
serotonin metabolic process
|
GO:0042428 |
8 |
0.124
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.124
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.123
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.123
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.123
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.122
|
|
|
|
positive regulation of renal sodium excretion
|
GO:0035815 |
2 |
0.122
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.120
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
33 |
0.120
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.119
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.119
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.118
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.118
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.118
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.117
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.117
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.116
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.116
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.116
|
Mouse |
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.116
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.115
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.114
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.114
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
23 |
0.114
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.113
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
11 |
0.113
|
|
|
|
response to isoquinoline alkaloid
|
GO:0014072 |
9 |
0.113
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.111
|
Mouse |
|
|
response to cocaine
|
GO:0042220 |
14 |
0.111
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.110
|
|
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.110
|
|
|
|
fear response
|
GO:0042596 |
33 |
0.110
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.109
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.108
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.107
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.107
|
|
|
|
grooming behavior
|
GO:0007625 |
16 |
0.107
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.107
|
|
|
|
central nervous system maturation
|
GO:0021626 |
6 |
0.107
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.106
|
|
|
|
negative regulation of cyclase activity
|
GO:0031280 |
1 |
0.106
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.101
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.101
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.100
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.099
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.099
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.098
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.097
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.097
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.096
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.096
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.095
|
|
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
5 |
0.094
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.094
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.093
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.093
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.093
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.093
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.092
|
|
|
|
indole containing compound metabolic process
|
GO:0042430 |
12 |
0.092
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.092
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.090
|
Mouse |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.090
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.090
|
|
|
|
primary amino compound metabolic process
|
GO:1901160 |
8 |
0.090
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.089
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.089
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.087
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.087
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.087
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.086
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.086
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.086
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.085
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.085
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.085
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.085
|
|
|
|
cardiac pacemaker cell fate commitment
|
GO:0060927 |
1 |
0.084
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.084
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.083
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.083
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.083
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.083
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.083
|
|
|
|
striatum development
|
GO:0021756 |
14 |
0.081
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.081
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.080
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.080
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.080
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.079
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.079
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.078
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.078
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.077
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.077
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.077
|
Rat |
|
|
positive regulation of fat cell proliferation
|
GO:0070346 |
1 |
0.077
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.076
|
|
|
|
regulation of high voltage gated calcium channel activity
|
GO:1901841 |
2 |
0.075
|
|
|
|
mesenchymal epithelial cell signaling involved in lung development
|
GO:0060496 |
1 |
0.075
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.074
|
|
|
|
diet induced thermogenesis
|
GO:0002024 |
7 |
0.074
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.074
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.073
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.072
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
22 |
0.072
|
Rat |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.072
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.072
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.072
|
|
|
|
saliva secretion
|
GO:0046541 |
6 |
0.072
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.071
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.070
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.070
|
|
|
|
adenohypophysis development
|
GO:0021984 |
14 |
0.069
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.069
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.069
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.069
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.069
|
|
|
|
regulation of white fat cell proliferation
|
GO:0070350 |
2 |
0.068
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.068
|
Rat |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.068
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.067
|
|
|
|
ceramide biosynthetic process
|
GO:0046513 |
20 |
0.067
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.066
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
8 |
0.066
|
|
|
|
long term synaptic depression
|
GO:0060292 |
13 |
0.066
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.066
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.065
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.065
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.065
|
|
|
|
regulation of renal sodium excretion
|
GO:0035813 |
3 |
0.065
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
29 |
0.064
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.064
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
5 |
0.064
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.064
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.064
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
27 |
0.063
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.063
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.063
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
14 |
0.063
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.062
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.061
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.061
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.061
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.061
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
16 |
0.060
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.059
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.059
|
|
|
|
developmental induction
|
GO:0031128 |
34 |
0.059
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.059
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.058
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.058
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.058
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.058
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.058
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.058
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.058
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.058
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.058
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.057
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.057
|
|